Lynn Hasher

University of Toronto | U of T · Psychology and Rotman Research Institute

Circadian rhythms are powerful timekeepers that drive physiological and intellectual functioning throughout the day. These rhythms vary across individuals, with morning chronotypes rising and peaking early in the day and evening chronotypes showing a later rise in arousal, with peaks in the afternoon or evening. Chronotype also varies with age from...

As a fundamental attention regulation process, inhibition serves to selectively filter out distraction (i.e., access), dampen activation of automatically activated irrelevant or no-longer-relevant information (i.e., deletion), and select for task-appropriate thoughts and/or responses in the face of competition (i.e., restraint). Inhibition allows u...

Background: Amnestic mild cognitive impairment (aMCI), a prodromal phase of Alzheimer's disease (AD), is characterized by episodic memory dysfunction, but inhibitory deficits have also been commonly reported. Time of day (TOD) effects have been confirmed in 1) healthy aging on cognitive processes such as inhibitory control, and 2) on behavior in A...

Healthy aging is accompanied by well-characterized shifts in memory systems: episodic memory tends to decline with age while semantic memory remains relatively intact, with some knowledge domains strengthening. Beyond reflecting on the past, these distinct memory systems often guide decisions about the future. Yet how such age-related memory shifts...

The mere-exposure effect, in which repeated stimuli are liked more than novel stimuli, is a well-known effect. However, little research has studied adult age differences in mere-exposure effects, despite possible applications in helping older adults transition to new living environments. Here, we report four experiments assessing mere-exposure to n...

Time of day (TOD) influences on executive functions have been widely reported, with greater efficiency demonstrated at optimal relative to non-optimal TOD according to one’s chronotype (i.e., synchrony effect). Older adults (OAs) show declines in inhibitory control and are more sensitive to the effects of circadian variation on executive functionin...

According to the inhibitory deficit hypothesis, older adults often fail to selectively inhibit distractors and attend to relevant information in working memory, leading to poorer memory of target items but better recall of irrelevant distractors compared to younger adults. Here, we explored how neural similarity of activity patterns between relevan...

Declines in episodic memory in older adults are typically attributed to differences in encoding strategies and/or retrieval processes. These views omit a critical factor in age-related memory differences: the nature of the representations that are formed. Here, we review evidence that older adults create more cluttered (or richer) representations o...

Aging is associated with altered brain connectivity within the default mode network (DMN). Although research using functional magnetic resonance imaging has quantified age-related alterations in functional connectivity within this network during resting state, it is less clear how this may be reflected in electrophysiological measures, and how this...

In humans, age-related declines in vision, hearing, and touch coincide with changes in amplitude and latency of sensory-evoked potentials. These age-related differences in neural activity may be related to a common deterioration of supra-modal brain areas (e.g., PFC) that mediate activity in sensory cortices or reflect specific sensorineural impair...

Previous work has shown that older adults with typical age-related memory changes (i.e., without cognitive impairment) pick up irrelevant information implicitly, and unknowingly use that information when it becomes relevant to a later task. Here, we address the possibility that implicit processes play a similarly beneficial role in the cognitive ab...

Prior learning can hinder subsequent memory, especially when there is conflict between old and new information. The ability to handle this proactive interference is an important source of differences in memory performance between younger and older participants. In younger participants, Oberauer et al. (2017) report evidence of proactive facilitatio...

The electrophysiological evidence for suppression to date primarily draws upon traditional retrieval-induced forgetting and Think/No-Think paradigms, which involve strategic and intentional restriction of thought. Here event-related potential (ERP) signatures of suppression were examined using a novel task, which unlike traditional paradigms, does...

Objectives Amnestic mild cognitive impairment (aMCI), a prodromal stage of Alzheimer’s disease and other dementias, is characterized by episodic memory impairment. Recent evidence has shown inhibitory control deficits in aMCI, but the extent of these deficits across inhibitory domains (i.e., response inhibition and interference control) and aMCI su...

Prior learning can hinder subsequent memory, especially when there is conflict between old and new information. The ability to handle this proactive interference is an important source of differences in memory performance between younger and older participants. In younger participants, Oberauer et al. (2017) report evidence of proactive facilitatio...

Background Research shows that older adults with memory‐support and complex‐care needs can meaningfully benefit from arts‐based activities because it can make them feel good, promote their sense of connection with personal and community identity, and stimulate thinking and memory. As a result, there is growing interest in integrating participatory...

The efficacy of a technology-driven visual arts recreation activity, delivered virtually, was evaluated for its potential to achieve positive impacts, similar to traditional arts-interventions, on wellbeing in long-term care residents. Thirty-one residents (average age 86.8 years; SD = 9.4) engaged with the arts-intervention for 30-minutes, twice w...

Reduced attentional control with age is associated with the processing and maintenance of task-irrelevant information in memory. Yet the nature of these memory representations remains unclear. We present evidence that, relative to younger adults (n = 48), older adults (n = 48) both (a) store simultaneously presented target and irrelevant informatio...

Inhibitory theory suggests that a major determinant of individual differences in cognitive performance (including differences that are typically observed with increasing age) is the ability to dampen down goal-irrelevant stimuli, thoughts, and actions. While this theory has garnered a lot of support over the years, it has also seen several challeng...

Optimal performance in many tasks requires minimizing the impact of both visual distraction and mind-wandering. Yet, so far, these two types of distraction have been studied in isolation and it remains unclear whether they act in similar or dissociable ways across age groups. Here, we studied the impact of visual distraction and mind-wandering on p...

Goal-relevant information can be maintained in working memory over a brief delay interval to guide an upcoming decision. There is also evidence suggesting the existence of a complementary process: namely, the ability to suppress information that is no longer relevant to ongoing task goals. Moreover, this ability to suppress or inhibit irrelevant in...

Objective Forgetting names is a common memory concern for people with amnestic mild cognitive impairment (aMCI) and is related to explicit memory deficits and pathological changes in the medial temporal lobes at the early stages of Alzheimer’s disease (AD). In the current experiment, we tested a unique method to improve memory for face–name associa...

Cambridge Core - Cognition - The Cambridge Handbook of Cognitive Aging - edited by Ayanna K. Thomas

Amnestic mild cognitive impairment (aMCI) is a prodromal stage of Alzheimer’s disease that is characterized by impairments in episodic memory. Recent evidence has shown that inhibitory control is also impaired in aMCI. The aim of the present meta-analysis was to quantify inhibitory control ability in individuals with aMCI by examining performance a...

Evidence suggests that age differences in associative memory are attenuated for associations that are consistent with prior knowledge. Such knowledge structures have traditionally been associated with the default network (DN), which also shows reduced modulation with age. In the present study, we investigated whether DN activity and connectivity pa...

It has been shown in literature that East Asians are more inclined to process context information than individuals in Western cultures. Using a context memory task that requires studying object images in social contexts (i.e., rating objects in an imagined social or experiential scenario), our recent study revealed an age-invariant advantage for Ch...

The final SPSS dataset “S1_file_PONE-D-18-05261_final data set”. (SAV)

Recent research found that implicit rehearsal of distraction can reduce forgetting for older adults, in part due to their inefficient regulation of irrelevant information. Here, we investigated whether young adults’ memory can also benefit from critical information presented as distraction. Participants recalled a list of words initially and then a...

Cultural differences in information processing affect perceptual judgment, attention, and memory. We investigated whether cultural differences in processing patterns, specifically East Asian participants’ tendency to encode holistically, compared to Western tendencies to process analytically, affect performance on an implicit memory test. First, pa...

We have previously shown that older adults hyper-bind, or form more extraneous associations than younger adults. In this study, we aimed to both replicate the original implicit transfer effect and to test whether younger adults show evidence of hyper-binding when informed about the relevance of past information. Our results suggest that regardless...

We examined the effect of age on listeners' ability to orient attention to an item in auditory short-term memory (ASTM) using high-density electroencephalography, while participants completed a delayed match-to-sample task. During the retention interval, an uninformative or an informative visual retro-cue guided attention to an item in ASTM. Inform...

Forgetting people’s names is a common memory complaint among older adults and one that is consistent with experimental evidence of age-related decline in memory for face-name associations. Despite this difficulty intentionally forming face-name associations, a recent study demonstrated that older adults hyperbind distracting names and attended face...

Older adults typically show poor associative memory performance relative to younger adults. This age-related effect, however, is mediated by the meaningfulness of the materials used, such that age differences are minimized with the use of information that is consistent with prior knowledge. While this effect has been interpreted as facilitative lea...

The presence of noise and interfering information can pose major difficulties during speech perception, particularly for older adults. Analogously, interference from similar representations during retrieval is a major cause of age-related memory failures. To demonstrate a suppression mechanism that underlies such speech and memory difficulties, we...

Previous work has shown that older adults attend to and implicitly remember more distracting information than young adults; however, it is unknown whether they show a corresponding decrease in implicit memory for targets in the presence of distracters. Using implicit memory tests, we asked whether older adults show a tradeoff in memory between targ...

Despite decades of research on younger adults, little is known about the way in which vigilant attention is affected by healthy aging, and the small body of work that does exist has yielded mixed findings. Prior examinations of aging and vigilant attention have focused almost exclusively on sensory/perceptual tasks despite the fact that many real-w...

Leisure participation is associated with health benefits and withdrawal from leisure is a commonly associated outcome of cognitive decline. We investigated the feasibility of a web-based app ‘ArtOnTheBrain’ to promote involvement in enjoyable recreation in seniors with cognitive decline. ArtOnTheBrain employs artwork focused activities involving le...

Using implicit tests, older adults have been found to retain conceptual knowledge of previously seen task-irrelevant information. While younger adults typically do not show the same effect, evidence from one study [Gopie, N., Craik, F. I. M., & Hasher, L. (2011). A double dissociation of implicit and explicit memory in younger and older adults. Psy...

Circadian rhythms influence performance on a broad range of cognitive tasks, including attention shifting, implicit learning, memory retrieval, suppression of distracting information, creativity, and problem solving. Much of the research on circadian arousal and cognition has examined the consequence of testing individuals at times that are synchro...

Interference between competing memory traces is a common cause of memory failure. Recent research has demonstrated a suppression mechanism that operates at retrieval to resolve interference. Using an adaptation of the suppression paradigm in Healey, Ngo, and Hasher [(2014). Below-baseline suppression of competitors during interference resolution by...

Older adults show implicit memory for previously seen distraction, an effect attributed to poor attentional control. It is unclear whether this effect results from lack of control over encoding during the distraction task, lack of retrieval constraint during the test task, or both. In the present study, we simulated poor distraction control in youn...

Cognitive control, the ability to limit attention to goal-relevant information, aids performance on a wide range of laboratory tasks. However, there are many day-to-day functions which require little to no control and others which even benefit from reduced control. We review behavioral and neuroimaging evidence demonstrating that reduced control ca...

Testing older adults in the morning generally improves behavioral performance relative to afternoon testing. Morning testing is also associated with brain activity similar to that of young adults. Here, we used graph theory to explore how time of day (TOD) affects the organization of brain networks in older adults across rest and task states. We us...

Older adults show decrements in the ability to ignore or suppress distraction relative to younger adults. However, age differences in the neural correlates of distraction control and the role of large-scale network interaction in regulating distractors are scarcely examined. In the current study, we investigated age differences in how the anticorre...

We assessed age differences in the ability to resolve competition for figural status in stationary displays using small, enclosed, symmetrical silhouettes that participants classified as depicting "novel" or "familiar" shapes. The silhouettes were biased such that the inside was perceived as the shaped figure, and the outside was perceived as a sha...

We investigated differences between participants of East Asian and Western descent in attention to and implicit memory for irrelevant words which participants were instructed to ignore while completing a target task (a Stroop Task in Experiment 1 and a 1-back task on pictures in Experiment 2). Implicit memory was measured using two conceptual primi...

Difficulty remembering faces and corresponding names is a hallmark of cognitive aging, as is increased susceptibility to distraction. Given evidence that older adults spontaneously encode relationships between target pictures and simultaneously occurring distractors (a hyper-binding phenomenon), we asked whether memory for face–name pairs could be...

The inhibitory deficit hypothesis, or inhibitory theory, is an attention-based, general model of cognition that accounts for age differences in patterns of spared and impaired functioning in healthy older adults, patterns also seen in other populations such as those with attention deficits, those with depression, and individuals who are out of phas...

There is a need for rapid and reliable Internet-based screening tools for cognitive assessment in middle-aged and older adults. We report the psychometric properties of an on-line tool designed to screen for cognitive deficits that require further investigation. The tool is composed of measures of memory and executive attention processes known to b...

Evidence from perceptually based implicit memory tasks demonstrates greater priming from distracting information among older compared with younger adults. We examined whether older adults also show greater conceptually based implicit priming from distracting information. We measured priming using a general-knowledge test that was preceded by an inc...

Behavioral evidence suggests that the attention-based ability to regulate distraction varies across the day in synchrony with a circadian arousal rhythm that changes across the life span. Using functional magnetic resonance imaging (fMRI), we assessed whether neural activity in an attention control network also varies across the day and with behavi...

Older adults’ decreased ability to inhibit irrelevant information makes them especially susceptible to the negative effects of simultaneously occurring distraction. For example, older adults are more likely than young adults to process distraction presented during a task, which can result in delayed response times, decreased reading comprehension,...

Resolving interference from competing memories is a critical factor in efficient memory retrieval, and several accounts of cognitive aging suggest that difficulty resolving interference may underlie memory deficits such as those seen in the elderly. Although many researchers have suggested that the ability to suppress competitors is a key factor in...

Difficulty with memory retrieval is a salient feature of cognitive aging and may be related to a reduction in the ability to suppress items that compete for retrieval. To test this hypothesis directly, we presented a series of words for shallow coding that included pairs of orthographically similar words (e.g., ALLERGY and ANALOGY). After a delay,...

Older adults show hyper- (or excessive) binding effects for simultaneously and sequentially presented distraction. Here, we addressed the potential role of hyper-binding in paired-associate learning. Older and younger adults learned a list of word pairs and then received an associative recognition task in which rearranged pairs were formed from ite...

The current study investigates whether long-term music training and practice are associated with enhancement of general cognitive abilities in late middle-aged to older adults. Professional musicians and non-musicians who were matched on age, education, vocabulary, and general health were compared on a near-transfer task involving auditory processi...

Research suggests that people in Eastern interdependent cultures process information more holistically and attend more to contextual information than do people in Western independent cultures. The current study examined the effects of culture and age on memory for socially meaningful item-context associations in 71 Canadians of Western European des...

In three experiments, we assessed whether older adults' generally greater tendency to process distracting information can be used to minimize widely reported age-related differences in forgetting. Younger and older adults studied and recalled a list of words on an initial test and again on a surprise test after a 15-min delay. In the middle (Experi...

Disorders of the brain and its sensory organs have traditionally been associated with deficits in movement, perception, cognition, emotion, and behavior. It is increasingly evident, however, that positive phenomena may also occur in such conditions, with implications for the individual, science, medicine, and for society. This article provides a se...

Positive mood states are believed to broaden the focus of attention in younger adults, but it is unclear whether the same is true for older adults. Here we examined one consequence of broader attention that has been shown in young adults: that memory for distraction is greater for those in a positive mood. In the current study, positive and neutral...

Introduction: Degraded social function, disinhibition, and stereotypy are defining characteristics of frontotemporal dementia (FTD), manifesting in both the behavioral variant of frontotemporal dementia (bvFTD) and semantic dementia (SD) subtypes. Recent neuroimaging research also associates FTD with alterations in the brain's intrinsic connectivi...

Objectives: Previously relevant information can disrupt the ability of older adults to remember new information. Here, the researchers examined whether prior irrelevant information, or distraction, can also interfere with older adults' memory for new information. Method: Younger and older adults first completed a 1-back task on pictures that wer...

To explore the influence of circadian rhythms on executive function during early adolescence, we administered a battery of executive function measures (including a Go-Nogo task, the Iowa Gambling Task, a Self-ordered Pointing task, and an Intra/Extradimensional Shift task) to Morning-preference and Evening-preference participants (N = 80) between t...

The relationships among working memory, inhibitory control, and reading skills were studied in 966 individuals, 6—49 years old. In addition to a standardized measure of word recognition, they received a working memory (listening span) task in the standard, blocked format (three sets containing two-, three-, or four-item trials) or in a mixed format...

Spina bifida meningomyelocele (SBM) is a neural tube defect that involves dysraphism of the spinal cord and extensive reorganization of the brain. The authors assessed the relationship between chronotype, diurnal preferences, and sleep problems in individuals with SBM and healthy controls. Although individuals with SBM showed the characteristic dec...

A literature on young adults reports that morning-type individuals, or "larks," report higher levels of positive affect compared with evening-type individuals, or "owls" (Clark, Watson, & Leeka, 1989; Hasler et al., 2010). Morning types are relatively rare among young adults but frequent among older adults (May & Hasher, 1998; Mecacci et al., 1986)...

Recent work has shown that older adults' lessened inhibitory control leads them to inadvertently bind co-occurring targets and distractors. Although this hyper-binding effect may lead to the formation of more superfluous associations, and thus greater interference at retrieval for older adults, it may also lead to a greater knowledge of information...

Recent research suggests that inhibition at early stages of visual processing may be age invariant. We test this proposal using a priming of pop-out (PoP) measure developed by Lamy, Antebi, Aviani, and Carmel (2008. Priming of pop-out provides reliable measures of target activation and distractor inhibition in selective attention. Vision Research,...

Three studies explored whether younger and older adults' free recall performance can benefit from prior exposure to distraction that becomes relevant in a memory task. Participants initially read stories that included distracting text. Later, they studied a list of words for free recall, with half of the list consisting of previously distracting wo...

Ageing is characterized by decreased brain volume, changes in general neuronal efficacy and connectivity and by a number of medical conditions, any or all of which contribute to widely reported age- related declines in cognition and memory . However, a number of findings in the recent literature suggest that the age- related declines do not charact...

Schmeichel (2007) reported that performing an initial task before completing a working memory span task can lower span scores and suggested that the effect was due to depleted cognitive resources. We showed that the detrimental effect of prior tasks depends on a match between the stimuli used in the span task and the preceding task. A task requirin...

Emotional states are known to influence how people process relevant information. Here, we address the impact of emotional state on irrelevant information. In this experiment, participants were randomly assigned to a neutral or positive mood induction, and then completed a task that involved viewing a sequence of overlapping pictures and words. They...

This study examined whether age-related differences in cognition influence later memory for irrelevant, or distracting, information. In Experiments 1 and 2, older adults had greater implicit memory for irrelevant information than younger adults did. When explicit memory was assessed, however, the pattern of results reversed: Younger adults performe...