Lydia Ior

University of Jos · Department of Pharmacology

Background Environmental concerns over the use of large quantities of synthetic insecticides for termite control owing to the huge pollution burdens and modern environmental health hazards (MEHH) of such chemicals on non-target living beings and other environmental element. To reduce the burden of such chemicals on the environment, the use of plant...

Peptic ulcer disease constitutes a major health challenge resulting in morbidity and in some cases, mortality. This study evaluated the phytochemistry, acute toxicity, and anti-ulcer activity of the methanol extracts of the stem bark of Anogeissus leiocarpus (DC.) Guill. & Perr. Flavonoids, tannins and saponins are some phytochemicals found in the...

Neural stem cells (NSCs) are immature progenitor cells that are found in developing and adult brains that have the potential of dividing actively and renewing themselves, with a complex form of gene expression. The generation of new brain cells in adult individuals was initially considered impossible, however, the landmark discovery of human neural...

The quest for sustainable health, environmental protection, and the conservation of beneficial organisms makes the use of biopesticides a desirable option. This research aimed to identify the botanicals used in the management of farm and household pests in Plateau State, Nigeria. A cross sectional study was carried out using semi-structured questio...

The quest for sustainable health, environmental protection and conservation of beneficial organisms makes the use of biopesticides a desirable option. This research aimed to identify botanicals used in the management of farm and household pest in Plateau State, Nigeria. A cross sectional study was carried out using semi-structured questionnaires an...

Substantial number of studies has been conducted to find alternatives or treatments for psychosis. Psychosis represents a variety of mental disorders characterized by the presence of delusions, hallucinations and grossly disorganized thinking in a clear sensorium. Psychosis is burdensome and difficult to treat given the inability of the typical and...

Psychosis is a chronic neuropsychiatric disorder that affects millions of individuals worldwide and impairs the quality of life and productivity of the patients. Terminalia macroptera Guill & Perr. (Combrataceae) is a plant that is used in the management of anxiety related disorders. The present study investigates the antipsychotic effects of ethyl...

Decoctions of Stereospermum kunthianum Cham are used in Nigeria's folk medicine for the management of epilepsy and their efficacies are commonly applauded among the rural communities of northern Nigeria. The aim of the study is to investigate the behavioural and anticonvulsant properties of the standardized methanol extract of the stem bark of S. k...

Objective: The effect of chronic and sub-chronic oral daily dose administration of the methanolic seed extract of Garcinia kola on serum level of LH, FSH, testosterone and pituitary tissues was investigated in male albino rats. Methods: The extract was administered daily by oral route for 20 and 60 days respectively in treated groups while normal s...

The present study deals with the pharmacognostic, acute toxicity and analgesic studies of the methanolic stem extract of Guiera senegalensis J.F. Gmel, family Combretaceae which is claimed by the Hausa in the Northern Nigeria to be used traditionally for the treatment of pain. The various features of the stem were observed macroscopically using the...

Background: The knowledge of mothers on immunization-a public health intervention that has greatly reduced mortality and morbidity globally-is very vital as they play a great role in child care. Their ability to have the right knowledge will enhance their practice and attitude towards immunization. This study was set to assess the knowledge, attitu...

Abstract- Cryptococcus neoformans is an opportunistic human pathogen that causes cryptococcosis, a life-threatening infection that is usually manifested as menigeoencephalitis mainly in immunocompromised patients. The objective of this study was to evaluate the presence of Cryptococcus neoformans from four environmental sources; water, soil poultry...

Malaria is a serious public health problem in the tropics. This study, investigated the mosquito repellent effect of the plant Azadirachta indica extracts of the seed kernel and fruit bark on human volunteers. Two different mosquito species were used, female anopheles and culex. It was observed that the fruit bark exhibited slight repellent activit...

The problem of increasing drug resistance in malaria therapy has made its treatment a major source of concern globally. This has necessitated the need to explore traditional medicines in the search for new/potential anti-malarials for both prophylaxis and chemotherapy. Cassia singueana and Cymbopogon citrutus are widely spread in northern Nigeria a...

A laboratory study was conducted on the pesticidal potentials of the aromatic plants Ocimum basilicum Linn and Hyptis spicigera Lamarck both of the family Lamiaceae against Callosobruchus maculatus (cowpea weevils), a pest of stored cowpeas. The essential oils produced by these plants which are a complex mixture of terpenes, sesquiterpenes, their o...

Authors' contributions This work was carried out in collaboration between all authors. KIA, NNW and HAI designed the study, wrote the protocol and wrote the first draft of the manuscript. LDI and GOC-O managed the literature searches and managed the analyses of the study. All the authors have read and approved the final manuscript. ABSTRACT Aim: To...

Ethanolic extract of the leaves of Syzygium guineense was investigated in rats and mice for analgesic and anti-inflammatory activities. The activities of the extract was tested on the egg white induced oedema, acetic acid induced writhing and hot plate pain models. The LD 50 of the ethanolic extract of S. guineense was found to be 3.807 g/kg. At co...

The ethanolic extract of the leaves of Paullinia pinnata was evaluated for its analgesic and anti-inflammatory activity. The analgesic effects were studied using two models: acetic acid-induced abdominal constriction test and hot plate method, in mice and rats respectively. The anti-inflammatory effect was investigated using egg white induced paw o...