Lutz Schega

Lutz Schega
OvG University Magdeburg · Health and Physical Activity

PhD, Prof. (Full)

About

104
Publications
27,581
Reads
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1,393
Citations
Additional affiliations
June 2015 - August 2015
The University of Queensland
Position
  • Professor (Visiting)
January 2012 - March 2012
Boston University
Position
  • Scientific Associate
March 2003 - October 2004
KU Leuven
Position
  • Research Assistant

Publications

Publications (104)
Article
Full-text available
Background Intermittent hypoxia applied at rest or in combination with exercise promotes multiple beneficial adaptations with regard to performance and health in humans. It was hypothesized that replacing normoxia by moderate hyperoxia can increase the adaptive response to the intermittent hypoxic stimulus. Objective Our objective was to systemati...
Article
Zusammenfassung Körperliche Aktivität in Form von Kraft- und Ausdauertraining kann zu einer akuten übungsinduzierten Hypoalgesie und chronischen Schmerzreduktion führen. Studien zeigen, dass vor allem hochintensive körperliche Aktivitäten diesen Effekt herbeiführen können. Insbesondere nach Verletzungen oder orthopädischen Eingriffen sind Patienten...
Article
Full-text available
Background: It was recently shown that intermittent hypoxic-hyperoxic exposure (IHHE) applied prior to a multimodal training program promoted additional improvements in cognitive and physical performance in geriatric patients compared to physical training only. However, there is a gap in the literature to which extent the addition of IHHE can enhan...
Article
Full-text available
There are conflicting results regarding the changes in spatio-temporal gait parameters during the 6-min walk test (6MWT) as indicators of gait-related motor performance fatigability (PF) in people with Multiple Sclerosis (pwMS). To further analyze if gait-related motor PF can be quantified using instrumented gait analysis during the 6MWT, we invest...
Article
Full-text available
Fatigue is one of the most limiting symptoms in people with Multiple Sclerosis (pwMS) and can be subdivided into trait and state fatigue. Activity-induced state fatigue describes the temporary decline in motor and/or cognitive performance (motor and cognitive performance fatigability, respectively) and/or the increase in the perception of fatigue (...
Article
Full-text available
There is considerable evidence showing that an acute bout of physical exercises can improve cognitive performance, but the optimal exercise characteristics (e.g., exercise type and exercise intensity) remain elusive. In this regard, there is a gap in the literature to which extent sprint interval training (SIT) can enhance cognitive performance. Th...
Article
Full-text available
Background Accumulating evidence shows that physical exercise has a positive effect on the release of neurotrophic factors and myokines. However, evidence regarding the optimal type of physical exercise for these release is still lacking. The aim of this study was to assess the acute and chronic effects of open-skill exercise (OSE) compared to clos...
Article
Full-text available
Gait phase detection in IMU-based gait analysis has some limitations due to walking style variations and physical impairments of individuals. Therefore, available algorithms may not work properly when the gait data is noisy, or the person rarely reaches a steady state of walking. The aim of this work was to employ Artificial Intelligence (AI), spec...
Article
Bielitzki, R, Behrendt, T, Behrens, M, and Schega, L. Current techniques used for practical blood flow restriction training: a systematic review. J Strength Cond Res XX(X): 000-000, 2021-The purpose of this article was to systematically review the available scientific evidence on current methods used for practical blood flow restriction (pBFR) trai...
Article
The main goal of musculoskeletal rehabilitation is to achieve the pre-injury and/or pre-surgical physical function level with a low risk of re-injury. Blood flow restriction (BFR) training is a promising alternative to conventional therapy approaches during musculoskeletal rehabilitation because various studies support its beneficial effects on mus...
Preprint
Full-text available
Considerable evidence has been accumulated showing that an acute bout of physical exercise can improve cognitive performance but the optimal exercise characteristics (e.g., exercise type and intensity) remain elusive. In this regard, there is a gap in the literature to which extent Sprint Interval Training (SIT) can enhance cognitive performance. T...
Article
Full-text available
Background Chronic low back pain (CLBP) is a common medical condition in adults over the age of 50. It is associated with severe disability, ranging from physical impairments to psychosocial distress. Since current treatments provide only small to moderate short-term effects, alternative interventions are required, whereby guidelines recommended mu...
Article
"Fatigue"has been defined differently depending on the field of research (e.g., neurology, psychology, exercise physiology), which has led to an inconsistent use of the term, limiting scientific progress. Therefore, this article proposes a taxonomy that promotes a better understanding of fatigue in people with multiple sclerosis (pwMS), allowing a...
Article
This article focuses on motor performance fatigability in people with multiple sclerosis (pwMS), which can be defined as the acute and temporary reduction in physical performance induced by a sustained motor task. Here, we provide an overview of the exercise protocols currently used to quantify motor performance fatigability in pwMS. The protocols...
Article
Full-text available
Background: There is growing evidence for a positive correlation between measures of muscular strength and cognitive abilities. However, the neurophysiological correlates of this relationship are not well understood so far. The aim of this study was to investigate cortical hemodynamics [i.e., changes in concentrations of oxygenated (oxyHb) and deo...
Article
Full-text available
Chronic low-back pain is a major individual, social, and economic burden. The impairment ranges from deterioration of gait, limited mobility, to psychosocial distress. Due to this complexity, the demand for multimodal treatments is huge. Our purpose is to compare the effects of a multimodal movement intervention (MI) (coordinative–cognitive exercis...
Article
Full-text available
Many established technologies are limited in analyzing the executive functions in motion, especially while walking. Functional near-infrared spectroscopy (fNIRS) fills this gap. The aim of the study is to investigate the inter-session reliability (ISR) of fNIRS-derived parameters at the prefrontal cortex while walking in people with multiple sclero...
Article
Zusammenfassung Das Primärziel muskuloskelettaler Rehabilitationsmaßnahmen orientiert auf die Wiederherstellung des prätraumatischen Leistungs- und Belastungsniveaus. Besonders infolge von orthopädischen Eingriffen oder nach Verletzungen sollte eine frühzeitige und progressive Rehabilitation erfolgen, um den Genesungsprozess optimal zu unterstützen...
Article
Full-text available
Background: Resistance training (RT) under hypoxic conditions has been used to increase muscular performance under normoxic conditions in young people. However, the effects of RT and thus of RT under hypoxia (RTH) could also be valuable for parameters of physical capacity and body composition across the lifespan. Therefore, we compared the effects...
Conference Paper
Hintergrund und Zielstellung: People suffering from Multiple Sclerosis (MS) are often impaired in locomotion (LaRocca, 2011). Hereby, fatigue is one of the most limiting symptoms in people with MS (pwMS) affecting over 80 % (Newland et al., 2016). (Kluger et al., 2013) differentiated between fatigue, the subjective feeling of exhaustion, and fatig...
Article
Full-text available
Introduction Accumulating evidence shows that acute resistance exercises and long-term resistance training positively influence cognitive functions, but the underlying mechanisms have been rarely investigated. One explanatory approach assumes that the execution of resistance exercises requires higher cognitive processes which, in turn, lead to an ‘...
Article
Full-text available
Background: During the aging process, physical capabilities (e.g., muscular strength) and cognitive functions (e.g., memory) gradually decrease. Regarding cognitive functions, substantial functional (e.g., compensatory brain activity) and structural changes (e.g., shrinking of the hippocampus) in the brain cause this decline. Notably, growing evide...
Article
Full-text available
In diesem Beitrag werden ausgewählte Fakten des aktuellen Kenntnisstandes zum Höhentraining in einem narrativen Überblick präsentiert. Dabei wird hinsichtlich der Wirkung unterschiedlicher Höhentrainingsmethoden vertiefend auf den Schwimmsport eingegangen. Es soll im deutschsprachigen Raum ein neuer Ausgangspunkt für den Einsatz des Höhentrainings...
Article
The aim of the current study was to evaluate the effect of a cognitive dual task on minimum toe clearance (MTC) variability while walking. In a randomized cross-over design, gait kinematics of 25 older (70 ± 6 years) and 45 younger adults (25 ± 2 years) were captured during normal walking and dual-task walking. Variability of stride time, stride le...
Conference Paper
Supervised and unsupervised machine learning algorithms were explored for gait segmentation using wearable sensor platform. Multiple wearable sensors modules were placed at key locations: Four Inertial Measurement Units (IMUs) were attached to the thigh and shank of each leg and a plantar pressure measuring foot insoles were implanted in the shoes....
Conference Paper
Gait is an extraordinary complex function of human body that involves the activation of entire visceral nervous system, making human gait definite to various functional abnormalities. Diagnosis and treatment of such disorders prior to their development can be achieved through integration of modern technologies with state-of-the-art developed method...
Poster
Full-text available
Locomotion is one of the most important capabilities associated with activities of daily living and influences the quality of life directly. People suffering from Multiple Sclerosis (MS) are often impaired in locomotion and most of them have gait deficits. Many studies have already addressed the MS induced change in gait pattern, but the compensato...
Article
Full-text available
The neuromotor control of walking relies on a network of subcortical and cortical structures. While kinematic differences between treadmill and overground walking are extensively studied, the neuromotor control processes are still relatively unknown. Hence, this study aims to investigate cortical activation during steady-state treadmill and overgro...
Article
Full-text available
Purpose: Erythropoietin (EPO) has multifactorial positive effects on health and can be increased by intermittent normobaric hypoxia (IH). Recommendations about the intensity and duration of IH to increase EPO exist, but only for young people. Therefore, the aim of the study was to investigate the dose–response relationship regarding the duration of...
Conference Paper
Introduction: Locomotion is an important capability associated with activities of daily living and influences the quality of life directly. People suffering from an inflammatory disease with neurodegenerative component such as Multiple Sclerosis (MS) are often impaired in locomotion and over 41% of these people with MS (pwMS) have gait deficits [1...
Article
Full-text available
Purpose: We aimed to investigate whether a blood flow restriction training (BFR) prior to a high intensity interval training (HIIT) leads to a higher increase in physical performance than a sole HIIT. Methods: 24 male participants (18 to 30 years) were randomly assigned to a BFR+HIIT or HIIT group which performed 3 times per week over 4 weeks a HII...
Article
Full-text available
Aging is accompanied by a decrease in physical capabilities (e.g., strength loss) and cognitive decline. The observed bidirectional relationship between physical activity and brain health suggests that physical activities could be beneficial to maintain and improve brain functioning (e.g., cognitive performance). However, the exercise type (e.g., r...
Presentation
1. Introduction Walking was generally considered as an automatic motor-task which does not rely on higher central nervous processes. This traditional view is challenged by recent evidence pointing towards a complicated neuromotor control of walking via a wide network of cortical and subcortical structures (Hamacher, Herold, Wiegel, Hamacher, & Sche...
Poster
Full-text available
Walking safely is a crucial ability for accomplishing most of the activities of daily living, independently. However, aging, injury or disease may change the gait and lead to higher risk of fall due to weakened lower-limb, poorer balance or other abnormal sensations. To be able to identify changes in gait pattern at an early stage, it is important...
Article
Background: While the effects of diseases, performance of proprioceptors, anxiety or pain on gait stability or automaticity of walking are well-explored, physical fatigue might be another relevant factor whose consequences are not sufficiently investigated, yet. Research question: The aim of the current study was to evaluate the effect of physical...
Poster
Background: Functional near-infrared spectroscopy (fNIRS) is a promising technique to assess cortical activity with the crucial advantage to be used in motion. An increase in cortical activity during dual-task walking is a predictor of falls in older individuals. Therefore, fNIRS measures could be capable markers to evaluate gait processes and to g...
Article
Full-text available
The demographic change in industrial countries, with increasingly sedentary lifestyles, has a negative impact on mental health. Normal and pathological aging leads to cognitive deficits. This development poses major challenges on national health systems. Therefore, it is necessary to develop efficient cognitive enhancement strategies. The combinati...
Presentation
Objective: Gait variability is an established marker to assess motor control of walking. Especially, the control of trunk movements during walking is pivotal to avoid falls. Another important role in avoiding falls plays the aspect of attention ensuring stable gait kinematics of the trunk. However, our knowledge about the cortical control of trunk...
Article
Full-text available
Hypoxic conditions diminish motor performance and cognitive functions, especially when the motor task and the cognitive task are conducted simultaneously. Hypoxia does further increase prefrontal cortex activity which provokes a reduced capability of efficient resource utilisation. This, again, might evoke that the capacity of the limited mental re...
Article
Full-text available
Safe locomotion is a crucial aspect of human daily living that requires well-functioning motor control processes. The human neuromotor control of daily activities such as walking relies on the complex interaction of subcortical and cortical areas. Technical developments in neuroimaging systems allow the quantification of cortical activation during...
Article
Gait variability is frequently used to evaluate the sensorimotor system and elderly fallers compared to non-fallers exhibit an altered variability in gait parameters during unchanged conditions. While gait variability is often interpreted as movement error, it is also necessary to change the gait pattern in order to react to internal and external p...
Article
Context: The use of isokinetic dynamometers playing an important role in different settings of sports and medicine. Therefore, a high reliability of these devices is required. Objective: The aim of this study was to examine the inter-session reliability of the dynamometer BTE PrimusRS regarding to the isolated single-joint exercises extension /...
Article
Full-text available
Rhythmic auditory cues aim to modulate step times while walking. Their effect on the variability of minimum foot clearance, which is “normally” the most controlled gait parameter in normal overground walking, has not been studied, yet. We aim to analyse the effects of auditory cues on the variability of foot clearance versus the variability of othe...
Article
Background: Pain has disruptive effects on cognitive functions leading to a decreased capability to multi task. This might be the reason why pain is a fall risk factor in dual-task situations. This study aims to relate a decrease/increase in pain severity with a decrease/increase in dual-task costs of gait variability, which is associated with fal...
Article
The control of minimum toe clearance (MTC, as quantified with its stride-to-stride variability during walking) is a promising marker to evaluate motor control. The control of MTC, compared to other gait parameters, was reported to have higher priority. The relationship between the control of MTC and other gait parameters should be examined to eluci...
Conference Paper
Full-text available
A multimodal corpus on human machine interaction in the area of health and fitness is introduced in this paper. It shows the interaction of users with a gait training system. The subjects pace through a training course four times. In the intermissions, they interact with a multimodal platform, where they are given feedback, they re-assess their per...
Article
Fatigue directly affects key features of the sensorimotor system which disorganizes voluntary control of movement accuracy. Local dynamic stability of walking is considered a sensitive measure for neuromuscular performance. To gain greater insight in the role of fatigue in motor behaviour in older and young adults during walking, the current experi...
Article
Die Bewegungstherapie hat sich als supportive Therapiemaßnahme in der Behandlung von Krebserkrankungen etabliert. Die wissenschaftliche Datenlage zur Effektivität bewegungstherapeutischer Interventionen ist für viele Krebsentitäten mittlerweile recht umfangreich, für das Harnblasenkarzinom jedoch noch begrenzt. Ziel des vorliegenden Beitrags ist es...
Article
Full-text available
Objectives: Physical exercise, especially aerobic training, improves physical performance and cognitive function of older people. Furthermore, it has been speculated that age-associated deteriorations in physical performance and cognitive function could be counteracted through exposures to passive intermittent normobaric hypoxia (IH). Thus, the pre...
Article
Gait variability is an important measure in clinical settings to diagnose older individuals with fall risk. This study examines whether a familiarization trial improves test-retest reliability of gait variability. Twenty-two older participants walked twice at 1 day and twice 7 days later. The standard deviations of stride length, swing time, stance...
Article
In the recent years, local dynamic stability of walking was frequently used to quantify motor control. Particularly, dual-task paradigms are used to assess a shift in gait control strategy to test walking in real life situations. Texting short messages while walking is a common motor-cognitive dual task of daily living. To able to monitor possible...
Article
Background Extreme levels of gait variability and local dynamic stability of walking are associated with risk of falling and reduced executive functions. However, it is not sufficiently investigated how gait variability and local dynamic stability of human walking develop in the course of a motor-cognitive intervention. As dancing implies high dema...
Article
Local dynamic stability is a critical aspect of stable gait but its assessment for use in clinical settings has not yet been sufficiently evaluated, particularly with respect to inertial sensors applied on the feet and/or trunk. Furthermore, key questions remain as to which state-space reconstruction is most reliable and valid. In this study, we ev...
Conference Paper
Research Question: Does gait control change when stride times are externally constrained by auditory cues and does an additional cognitive load given to young and older individuals influence this potential effect? Introduction: Movement variability does not always interfere with task performance. Hence, controlling movement variability which does n...
Research
Full-text available
Increase of BDNF in response to normobaric hypoxia in humans Introduction The exposure to natural or simulated altitude leads to multifaceted physiological adaptations. The majority of these adaptations is associated with the hypoxia-inducible factor-1 (HIF-1) which is a master regulator of oxygen homeostasis (Se-menza, 1997). The attendance of HIF...
Article
Increased gait variability is common in chronic low back pain patients, which is a sign of their diminished proprioceptive feedback. When proprioceptive information is reduced, vision partly takes over the role of proprioception. Therefore, a loss of visual feedback would have a more negative effect in individuals with diminished proprioception. To...
Article
Background: After treatment for localized prostate cancer, many survivors experience severe physical and psychological/psychosocial impairments, such as urinary incontinence, erectile dysfunction, fatigue, depressive symptoms and decreased physical functioning. Physical activity and exercise can positively influence such side effects and improve q...
Article
This systematic review provides an overview of the literature deducing information about brain activation during 1) imagined walking using MRI/fMRI or 2) during real walking using measurement systems as fNIRS, EEG and PET. Three independent reviewers undertook an electronic database research browsing six databases. The search request consisted of t...
Article
Augmented feedback is frequently used in gait training to efficiently correct specific gait patterns in patients with different disorders. The patients use this external augmented feedback to align actual movements in a way that predefined gait characteristics can be achieved. Voluntary changes of gait characteristics are reported to reduce local d...
Conference Paper
Introduction/Background: Pain and extreme levels of gait variability in dual-task situations are associated with higher fall risk. Pain, however, is a fall risk factor which seems to be continually disregarded [1, 2]. A possible cause explaining why pain increases fall risk in an everyday dual-task situation might be that pain interferes with execu...
Conference Paper
Background: Extreme levels of gait variability are associated with fall risk (Hamacher et al., 2011) and reduced executive function. As walking demands cognitive effort, gait variability is affected when subjects perform a dual task. It is not verified if dual-task walking improves after a cognitive-motor intervention. Dancing implies high demands...
Conference Paper
Full-text available
Introduction The exposure to hypoxia in both altitude and simulated conditions are valid methods used to improve physical performance at sea-level or altitude. This is affected by a hypoxia-induced increase of erythropoiesis which leads to an increased oxygen uptake. These mechanisms are only investigated for young people, yet. It is promising to u...
Article
Full-text available
Dancing is a complex sensorimotor activity involving physical and mental elements which have positive effects on cognitive functions and motor control. The present randomized controlled trial aims to analyze the effects of a dancing program on the performance on a motor-cognitive dual task. Data of 35 older adults, who were assigned to a dancing gr...
Article
Objective Gait variability is frequently used to identify rehabilitation progresses in orthopedic and neurologic diseases by means of repeated testing. However, learning effects are a significant issue. This study examined if the inter-day reliability of gait variability parameters improves with an additional familiarization trial. Design Within a...