Lungile PepetaNelson Mandela University | NMMU · Faculty of Health Sciences
Lungile Pepeta
MBChB (Unitra), DCH (SA), FC. Paed. (SA), Cert. Cardiology (SA), MMed. (Wits), FSCAI
About
17
Publications
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Introduction
Publications
Publications (17)
Background:
This is a report on percutaneous closure of patent ductus arteriosus (PDA) using Amplatzer Duct Occluder type two additional sizes (ADO II AS) in patients under 6 kg.
Methods:
Prospective data were collected and a review of Patients' records was conducted. Demographics, and angiographic and clinical outcomes are reported in this arti...
We report data from an observational cohort of South African children living with HIV <12 years of age eligible for fast track ART (rapid) initiation. We found that less than half those eligible for rapid ART initiation based on immunologic and disease status started treatment within one week.
We present a case of Fontan fenestration closure using
an Occlutech patent ductus arteriosus occluder. The
patient was diagnosed with tricuspid atresia, pulmonary
atresia and secundum ASD at birth. He had a
bilateral modifi ed Blalock-Taussig shunt to promote
growth of hypoplastic branch pulmonary arteries. He
had a bidirectional Glenn Shunt at 11...
Introduction
There are limited data on viral suppression (VS) in children with HIV receiving antiretroviral therapy (ART) in routine care in low‐resource settings. We examined VS in a cohort of children initiating ART in routine HIV care in Eastern Cape Province, South Africa.
Methods
The Pediatric Enhanced Surveillance Study enrolled HIV‐infected...
We present a case of an 8-year-old girl with bilateral,
diffuse, lower lobe pulmonary arteriovenous malformations
(PAVMs). These were initially treated by selective
embolisation of the feeder arteries with coils and vascular
plugs. Due to unsatisfactory results (persistent
cyanosis and diffuse residual PAVMs), prolonged procedure
time, high contras...
Background: Acute rheumatic fever (ARF) is a post infectious, non-suppurative sequela of pharyngeal infection with Streptococcal
pyogens, or group A beta hemolytic streptococcus. Africa has one of the highest prevalence of heart disease in children and young
adults, including congenital heart disease (CHD) and rheumatic heart disease (RHD). The inc...
Introduction:
Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa.
Methods:
Electronic medical records for all chi...
Background: Percutaneous closure of patent ductus arteriosus (PDA) has become standard therapy. Experience with the Occlutech® Duct Occluder is limited.
Methods: Data regarding ductal closure using Occlutech® Duct Occluder were reviewed and prospectively collected. Demographics, hemodynamic and angiographic characteristics, complications, and outco...
Background:
The incidence of acute rheumatic fever (ARF) and rheumatic heart disease (RHD) has waned in Western countries, however that is not the situation in developing nations.
Methods:
Records were reviewed of patients from the Eastern Cape municipal districts who presented to the Paediatric Cardiology Unit with ARF and RHD from January 2008...
Heart failure is due to failure of ventricular filling with failure of ejection of blood from the ventricles. It may present as volume overload with ventricular dysfunction, volume overload with preserved ventricular function, and pressure overload. Causes of heart failure in the paediatric age group include both congenital and acquired heart disea...
We report on two cases presenting with a rare combination of Ebstein's anomaly and Down's syndrome. The first patient presented with respiratory distress, mild cyanosis and right heart failure immediately after delivery. The symptoms improved with heart failure medication. The patient remained asymptomatic on follow up. The second patient was diagn...
To report outcomes in percutaneous ductal closure using the Amplatzer duct occluder type two (ADO II).
Records of patients admitted for percutaneous closure of patent ductus arteriosus (PDA) were reviewed.
From May 2009 to July 2012, 36 patients were assigned to closure using the ADO II. There were 21 females and 15 males. The median age was 16.5 (...
BACKGROUND
Cardiovascular disease is a common complication of advanced HIV disease in both paediatric and adult patient groups and may present with left ventricular (LV) dysfunction. Introduction of Highly Active Antiretroviral Therapy (HAART) has improved outcomes in patients presenting with LV dysfunction. However, mitochondrial toxicity, a compl...
Objective:
To analyse the outcome of children with left ventricular dysfunction placed on Highly Active Antiretroviral Therapy.
Method:
This study is a retrospective review of records of Human Immunodeficiency Virus-positive children with left ventricular dysfunction. Demographic data were collected. Left ventricular fractional shortening, CD4 p...
We report two rare cases of an anomalous origin of the left pulmonary artery (AOLPA) from the ascending aorta, associated with pulmonary atresia, a ventricular septal defect and a left aortic arch. The cases are unusual because AOLPA is more commonly associated with a right aortic arch and it is more usual for the right pulmonary artery to originat...