Lungile Pepeta

Lungile Pepeta
Nelson Mandela University | NMMU · Faculty of Health Sciences

MBChB (Unitra), DCH (SA), FC. Paed. (SA), Cert. Cardiology (SA), MMed. (Wits), FSCAI

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17
Publications
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80
Citations

Publications

Publications (17)
Article
Full-text available
Background: This is a report on percutaneous closure of patent ductus arteriosus (PDA) using Amplatzer Duct Occluder type two additional sizes (ADO II AS) in patients under 6 kg. Methods: Prospective data were collected and a review of Patients' records was conducted. Demographics, and angiographic and clinical outcomes are reported in this arti...
Article
We report data from an observational cohort of South African children living with HIV <12 years of age eligible for fast track ART (rapid) initiation. We found that less than half those eligible for rapid ART initiation based on immunologic and disease status started treatment within one week.
Article
Full-text available
We present a case of Fontan fenestration closure using an Occlutech patent ductus arteriosus occluder. The patient was diagnosed with tricuspid atresia, pulmonary atresia and secundum ASD at birth. He had a bilateral modifi ed Blalock-Taussig shunt to promote growth of hypoplastic branch pulmonary arteries. He had a bidirectional Glenn Shunt at 11...
Article
Full-text available
Introduction There are limited data on viral suppression (VS) in children with HIV receiving antiretroviral therapy (ART) in routine care in low‐resource settings. We examined VS in a cohort of children initiating ART in routine HIV care in Eastern Cape Province, South Africa. Methods The Pediatric Enhanced Surveillance Study enrolled HIV‐infected...
Article
Full-text available
We present a case of an 8-year-old girl with bilateral, diffuse, lower lobe pulmonary arteriovenous malformations (PAVMs). These were initially treated by selective embolisation of the feeder arteries with coils and vascular plugs. Due to unsatisfactory results (persistent cyanosis and diffuse residual PAVMs), prolonged procedure time, high contras...
Article
Full-text available
Background: Acute rheumatic fever (ARF) is a post infectious, non-suppurative sequela of pharyngeal infection with Streptococcal pyogens, or group A beta hemolytic streptococcus. Africa has one of the highest prevalence of heart disease in children and young adults, including congenital heart disease (CHD) and rheumatic heart disease (RHD). The inc...
Article
Full-text available
Introduction: Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa. Methods: Electronic medical records for all chi...
Article
Full-text available
Background: Percutaneous closure of patent ductus arteriosus (PDA) has become standard therapy. Experience with the Occlutech® Duct Occluder is limited. Methods: Data regarding ductal closure using Occlutech® Duct Occluder were reviewed and prospectively collected. Demographics, hemodynamic and angiographic characteristics, complications, and outco...
Article
Full-text available
Background: The incidence of acute rheumatic fever (ARF) and rheumatic heart disease (RHD) has waned in Western countries, however that is not the situation in developing nations. Methods: Records were reviewed of patients from the Eastern Cape municipal districts who presented to the Paediatric Cardiology Unit with ARF and RHD from January 2008...
Article
Full-text available
Heart failure is due to failure of ventricular filling with failure of ejection of blood from the ventricles. It may present as volume overload with ventricular dysfunction, volume overload with preserved ventricular function, and pressure overload. Causes of heart failure in the paediatric age group include both congenital and acquired heart disea...
Article
We report on two cases presenting with a rare combination of Ebstein's anomaly and Down's syndrome. The first patient presented with respiratory distress, mild cyanosis and right heart failure immediately after delivery. The symptoms improved with heart failure medication. The patient remained asymptomatic on follow up. The second patient was diagn...
Article
Full-text available
To report outcomes in percutaneous ductal closure using the Amplatzer duct occluder type two (ADO II). Records of patients admitted for percutaneous closure of patent ductus arteriosus (PDA) were reviewed. From May 2009 to July 2012, 36 patients were assigned to closure using the ADO II. There were 21 females and 15 males. The median age was 16.5 (...
Thesis
Full-text available
BACKGROUND Cardiovascular disease is a common complication of advanced HIV disease in both paediatric and adult patient groups and may present with left ventricular (LV) dysfunction. Introduction of Highly Active Antiretroviral Therapy (HAART) has improved outcomes in patients presenting with LV dysfunction. However, mitochondrial toxicity, a compl...
Article
Full-text available
Objective: To analyse the outcome of children with left ventricular dysfunction placed on Highly Active Antiretroviral Therapy. Method: This study is a retrospective review of records of Human Immunodeficiency Virus-positive children with left ventricular dysfunction. Demographic data were collected. Left ventricular fractional shortening, CD4 p...
Article
Full-text available
We report two rare cases of an anomalous origin of the left pulmonary artery (AOLPA) from the ascending aorta, associated with pulmonary atresia, a ventricular septal defect and a left aortic arch. The cases are unusual because AOLPA is more commonly associated with a right aortic arch and it is more usual for the right pulmonary artery to originat...

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