Luke Hughes

Luke Hughes
Northumbria University · Sports Exercise and Rehabilitation

Doctor of Philosophy

About

36
Publications
19,027
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Citations
Introduction
Postdoc in Aerospace Physiology & Biomechanics within the Aerospace Medicine and Rehabilitation Laboratory, at Northumbria University. Working in collaboration with ESA and NASA, key projects include: 1) Investigating lumbopelvic deconditioning and reconditioning in astronauts following ISS missions; 2) Investigating lumbopelvic deconditioning and reconditioning during prolonged bedrest. Additional line of research is developing Blood Flow Restriction Exercise as a countermeasure to spaceflight.
Additional affiliations
February 2019 - February 2021
St Mary's University, Twickenham
Position
  • PostDoc Position
December 2016 - present
University College London
Position
  • Lecturer
Description
  • Guest lecturer in blood flow restriction training
September 2016 - present
St. Mary’s University
Position
  • Lecturer
Description
  • Lecturer in Exercise Immunology, Physiology & Anatomy
Education
February 2016 - February 2019
St Mary's University, Twickenham
Field of study
  • Exercise physiology/clinical rehabilitation
September 2014 - September 2015
Loughborough University
Field of study
  • Exercise Physiology/Immunology
September 2011 - July 2014
Loughborough University
Field of study
  • Sport and Exercise Science

Publications

Publications (36)
Article
Full-text available
Background: Blood flow restriction exercise (BFRE) has become a common method to increase skeletal muscle strength and hypertrophy for individuals with a variety of conditions. A substantial literature of BFRE in older adults exists in which significant gains in strength and functional performance have been observed without report of adverse events...
Article
INTRODUCTION: During spaceflight missions, astronauts work in an extreme environment with several hazards to physical health and performance. Exposure to microgravity results in remarkable deconditioning of several physiological systems, leading to impaired physical condition and human performance, posing a major risk to overall mission success and...
Article
During spaceflight missions, astronauts work in an extreme environment with several hazards to physical health and performance. Exposure to microgravity results in remarkable deconditioning of several physiological systems, leading to impaired physical condition and human performance, posing a major risk to overall mission success and crew safety....
Article
Aim: This study examined the effect of aerobic exercise with and without blood flow restriction on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid systems. Methodology: In a randomised crossover design, pain-free individuals performed 20 min of cycling in four experimental trials: 1) Low intensity aerobic exercise (LI-AE)...
Article
Full-text available
Background Development of automatic, pneumatic tourniquet technology and use of personalised tourniquet pressures has improved the safety and accuracy of surgical tourniquet systems. Personalisation of tourniquet pressure requires accurate measurement of limb occlusion pressure (LOP), which can be measured automatically through two different method...
Article
Aim: This study aimed to investigate and compare the magnitude of exercise-induced hypoalgesia (EIH) with low intensity blood flow restriction (BFR) resistance exercise (RE) at varying pressures to other intensities of resistance exercise and examine endogenous mechanisms of pain reduction. Methodology: Twelve individuals performed four experime...
Chapter
In the early phases following surgery of the lower limb, patients experience a loss of skeletal muscle and strength which if untreated can have a negative impact on return to normal function. To date, the techniques used in the rehabilitation process may not fully maximise the potential adaptations a patient may achieve due to the levels of loading...
Article
Full-text available
Background We implemented a blood flow restriction resistance training (BFR-RT) intervention during an 8-week rehabilitation programme in anterior cruciate ligament reconstruction (ACLR) patients within a National Health Service setting. Objective To compare the effectiveness of BFR-RT and standard-care traditional heavy-load resistance training (...
Article
Full-text available
The current manuscript sets out a series of guidelines for blood flow restriction exercise, focusing on the methodology, application and safety of this mode of training. With the emergence of this technique and the wide variety of applications within the literature, the aim of this review is to set out a current research informed guide to blood flo...
Article
Exercise-induced hypoalgesia is characterised by a reduction in pain sensitivity following exercise. Recently, low intensity exercise performed with blood flow restriction has been shown to induce hypoalgesia. The purpose of this manuscript is to discuss the mechanisms of exercise-induced hypoalgesia and provide rationale as to why low intensity ex...
Article
Objective Examine the comfort and pain experienced with blow flow restriction resistance training (BFR-RT) compared to standard care heavy load resistance training (HL-RT) during anterior cruciate ligament reconstruction (ACLR) patient rehabilitation. Design Randomised controlled trial. Setting United Kingdom National Health Service. Participant...
Article
Full-text available
The current manuscript sets out a position stand for blood flow restriction exercise, focusing on the methodology, application and safety of this mode of training. With the emergence of this technique and the wide variety of applications within the literature, the aim of this position stand is to set out a current research informed guide to blood f...
Article
Objectives: To compare the acute perceptual and blood pressure responses to: 1) light load blood flow restriction resistance exercise (BFR-RE) in non-injured individuals and anterior cruciate ligament reconstruction (ACLR) patients; and 2) light load BFR-RE and heavy load RE (HL-RE) in ACLR patients. Design: Between-subjects, partially-randomise...
Article
Full-text available
Background Total arterial occlusive pressure (AOP) is used to prescribe pressures for surgery, blood flow restriction exercise (BFRE) and ischemic preconditioning (IPC). AOP is often measured in a supine position; however, the influence of body position on AOP measurement is unknown and may influence level of occlusion in different positions during...
Article
Full-text available
Background: The aim of this study was to compare the effect of local and remote ischemic preconditioning (IPC) on repeated sprint exercise. Methods: Twelve males (age 22 ± 2 years; stature 1.79±0.07 m; body mass 77.8±8.4 kg; mean ± SD) completed four trials consisting of remote (arm) and local (leg) IPC and SHAM interventions prior to repeated s...
Data
Raw data set for AOP. Raw data for LOP measurement in different body positions.
Article
This study examined the cuff to limb interface pressure during blood flow restriction (BFR), and the perceptual and mean arterial pressure responses, in different BFR systems. Eighteen participants attended three experimental sessions in a randomised, crossover, counterbalanced design. Participants underwent inflations at 40% and 80% limb occlusive...
Article
Anterior cruciate ligament (ACL) rupture is a highly prevalent orthopedic injury, resulting in substantial skeletal muscle atrophy because of changes in muscle protein balance and satellite cell abundance. Neural activation problems also contribute to strength loss, impacting upon a patients’ physical function and rehabilitative capacity. Heavy loa...
Article
Strength training forms a pivotal part of rehabilitation. Heavy-load strength training (60%–70% one-repetition maximum (1RM)) has been traditionally prescribed to improve muscle strength, body mass and function, 1 but may be unat-tainable and/or confer increased risk of adverse consequences in individuals with a musculoskeletal (MSK) impairment. Th...
Article
Background and objective Low-load exercise training with blood flow restriction (BFR) can increase muscle strength and may offer an effective clinical musculoskeletal (MSK) rehabilitation tool. The aim of this review was to systematically analyse the evidence regarding the effectiveness of this novel training modality in clinical MSK rehabilitation...

Projects

Projects (9)
Project
The purpose of this project is to investigate blood flow restriction exercise as a potential exercise countermeasure for spaceflight. This project will utilise the Variable Gravity Suspension System within the Aerospace Medicine and Rehabilitation Laboratory at Northumbria University. Initial project work will involve a series of studies investigating the effectiveness, feasibility and safety of performing blood flow restriction exercise in simulated microgravity and different levels of hypogravity.
Project
The aim of this project is to develop a simple method of evaluating lumbopelvic deconditioning and reconditioning in astronauts and individuals with lower pain back on Earth. This involves conducting research on NASA and ESA astronauts before and after missions to the ISS, and during prolonged bed rest, in collaboration with ESA's Space Medicine Team.
Project
The aim of this project is to examine the influence of different body positions on limb occlusive pressure measurement.