Luisa Margarida Cabral Vieira

• MD
• Central Lisbon Hospital Center

Purpose: To identify systemic and/or ophthalmologic predictors of proliferative sickle retinopathy. Methods: Cross-sectional study comparing clinical, laboratory, and structural choriorretinal aspects between sickle cell disease patients with and without proliferative retinopathy. Patients underwent complete systemic and ophthalmologic evaluatio...

Central retinal artery occlusion (CRAO) is a rare but blinding disorder. We present a case of a 81-year-old woman with multiple cardiovascular comorbidities admitted to the emergency department due to sudden, painless vision loss on left eye (oculus sinister (OS)) on awakening. The patient also reported long standing fatigue associated with effort...

Purpose To evaluate the potential role of Magnetic Resonance Imaging (MRI) in the diagnosis of uveal melanoma. Methods Retrospective case series involving a total of 10 patients, 9 with uveal melanoma and 1 with a suspicious melanocytic lesion, diagnosed by A‐mode and B‐mode ultrasound (US) scan. 6 of the 10 patients simultaneously performed MRI f...

Purpose: To study structural chorioretinal changes in tamoxifen-treated patients. Methods: Cross-sectional case-control study comparing structural chorioretinal aspects in tamoxifen-treated patients and healthy controls. Enhanced depth spectral domain optic coherence tomography with choroidal binarization and optic coherence tomography angiograp...

Purpose: The authors present a case report of age-related macular degeneration (AMD) and provide a review on the clinical and pathological evidence on outer retinal tubulations (ORT) and the clinical utility of spectral-domain optical coherence tomography imaging (SD-OCT) in the evaluation and follow-up of patients with AMD. Methods: Case report an...

Purpose: To analyze the area of retinal nonperfusion in branch retinal vein occlusion (BRVO) and its relation to retinal ganglion cell (RGC) layer thickness. Procedures: Patients with ischemic BRVO, with no signs of fluid, were evaluated by Cirrus HD-OCT-A, Zeiss. Nonperfusion findings and RGC layer thickness were evaluated in a 6x6 mm area centere...

Purpose The differential diagnosis between Irvine‐Gass Syndrome (IGS) and Diabetic Macular Edema (DME) is currently established by angiography, which is an invasive and time‐consuming tool. The aim of this study is to evaluate differences in optic disc's nerve fiber layer thickness (RNFL) in patients with macular edema associated with IGS and Diabe...

Purpose The aim of this study was to evaluate and compare macroscopic and microscopic morphological features of functioning filtering blebs after XEN Gel Stent (XEN) implantation and trabeculectomy. Methods Prospective, observational case-control study of 10 eyes submitted to XEN implantation, 10 eyes submitted to trabeculectomy and 11 control eye...

Purpose Hydroxychloroquine has been used for decades in treatment of rheumatic disorders. Macular toxicity is an adverse effect dependent to duration of treatment and daily dosage. Although, the exactly retinal structure under this toxic effect is not yet totally understandable. To study the sectorial effect of Hydroxychloroquine in all retinal lay...

The purpose of this study is to evaluate the macular ganglion cell layer (GCL) and peripapillary retinal nerve fibre layer (RNFL) thickness in patients with unilateral posterior cerebral artery (PCA) ischaemic lesions using spectral-domain optical coherence tomography (SD-OCT). A prospective, case-control study of patients with unilateral PCA lesio...

Acute lymphoblastic leukemia is a malignant hematopoietic neoplasia, which is rare in adults. Although ocular fundus alterations may be commonly observed in the course of the disease, such alterations are rarely the presenting signs of the disease. Here we describe the case of a patient with painless and progressive loss of visual acuity (right eye...

Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy. Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were an...

Purpose To investigate the prevalence of CYP1B1 mutations in Portuguese children with primary congenital glaucoma (PCG) and to study the possible correlations between the mutation status and clinical features of the disease. Methods DNA sequencing analysis of the CYP1B1 gene was used to screen 21 children with PCG followed on Paediatric Ophthalmol...

To analyze the retinal ganglion cell layer (RGL) by optical coherence tomography (OCT) in toxic and nutritional optic neuropathy and to correlate its thickness and volume with functional damage. We conducted an observational cross-sectional study in healthy subjects and in patients with toxic optic neuropathy observed in the Neuro-Ophthalmology Dep...

Purpose: The authors present a case report of toric IOL and capsular bag tension ring implantation in a patient with zonular dehiscence. Setting: Centro Hospitalar Lisboa Central, Lisbon, Portugal Methods: A 72 years old patient with zonular dehiscence was submitted to phacoemulsification and a capsular bag tension ring (InjectoRing®, AMO) was im...

Purpose: The compression of the optic chiasm by lesions such as pituitary adenoma can compromise visual function. The relationship between functional and structural measurements is extremely important in the management of diseases of the anterior visual pathways. The authors present an analysis of the retinal nerve fiber layer measurements and visu...

Purpose To evaluate macroscopic and microscopic morphological features of filtering blebs after trabeculectomy with Mitomycin C (MMC) or 5‐Fluorouracil (5‐FU) and correlate them with function. Methods Retrospective case control study of 28 eyes (21 patients) submitted to trabeculectomy (15 with MMC and 13 with 5‐FU) and 11 eyes (10 patients) treate...

Purpose To evaluate the clinical presentation, microbiological results and treatment used in cases of infectious keratitis diagnosed in Centro Hospitalar Lisboa Central (CHLC) between July 2009 and July 2013 Methods Retrospective analysis of data from patients who underwent microbiological examination for suspected infectious keratitis between July...

Purpose To determine the reproducibility of keratometric parameters obtained by OCULUS® Pentacam® HR in the evaluation of keratoconus progression. Methods Thirty nine eyes of 25 patients from the Cornea Department of the Centro Hospitalar de Lisboa Central were included in the study. Fourteen eyes presented with clinical and topographic diagnosis o...

Purpose To assess whether corneal confocal microscopy (CCM) can detect alterations in corneal nerve morphology in patients with Parkinson disease. Methods Twenty‐five patients with Parkinson disease and 25 control subjects were examined. Patients underwent neurological and complete ophthalmological evaluation. Corneal sensitivity testing was perfor...

Purpose To analyse corneal nerve morphology alterations in patients with chronic renal failure by in vivo corneal confocal microscopy (CCM). Methods A prospective study was conducted in 30 patients (30 eyes) with pre‐dialysis chronic renal failure (CRF) and 30 aged‐matched healthy volunteers (30 eyes). A complete ophthalmologic examination, esthesi...

Purpose The authors present an analysis of the automated macular ganglion cell complex measurements in patients with compressive chasmal lesions. Methods Observational study of 20 eyes of 20 patients with compressive chiasmal lesions followed at the neurophthalmology outpatient clinic. Optical Coherence Tomography (OCT SPECTRALIS® ‐ Heidelberg Engi...

Purpose To analyze the ganglion cell complex (GCC) by optical coherence tomography (OCT) in Parkinson´s disease and to correlate it with disease´s severity and duration. Methods We conducted a prospective, case‐control study, in healthy subjects and in patients with Parkinson´s disease (PD). Full ophthalmologic examination, OCT (Spectralis ®) and n...

Purpose: To describe the technique of deep sclerectomy with the new Esnoper-Clip® implant, the clinical outcome and the anatomic characteristics of filtering blebs, using anterior segment optical coherence tomography (AS-OCT). Methods: A prospective case-series study was conducted in five eyes (5 patients) with open angle glaucoma. The fornix-ba...

Purpose: The authors present an analysis of subsequent surgical procedures performed and outcomes in patients with keratoconus following intracorneal ring segment insertion. Setting: Department of Ophthalmology - Centro Hospitalar Lisboa Central - Lisbon, Portugal Methods: A retrospective study of 422 eyes (326 patients) with keratoconus submitted...

Purpose: The authors present an analysis of the indications, outcomes and complications of amniotic membrane transplantation in patients with ocular surface disease. Setting/Venue: Department of Ophthalmology - Centro Hospitalar Lisboa Central - Lisbon, Portugal. Methods: A retrospective study of 44 eyes of 42 patients with ocular surface disease s...

Purpose: The authors present a comparison between intraocular pressure (IOP) measurements with dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) after corneal ring segment implantation in patients with keratoconus. Setting/Venue: Department of Ophthalmology - Centro Hospitalar Lisboa Central - Lisbon, Portugal. Methods: A tra...

Purpose: To evaluate the clinical outcomes of patients with suprachoroidal drainage devices. Methods: The authors describe 4 cases of patients presenting with preoperative intraocular pressures (IOP) between 30-40 mmHg, under triple glaucoma medication and history of multiple intraocular surgeries, who underwent suprachoroidal drainage device (Star...

Purpose: To compare intraocular pressure (IOP) measurements with dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) after Descemet’s stripping automated keratoplasty (DSAEK). Setting: Department of Ophthalmology - Centro Hospitalar Lisboa Central - Lisbon, Portugal Methods: Transverse observational study of 22 eyes of 19 pat...

Purpose: To present the surgical management with anterior chamber IOLs of 10 patients with spontaneous IOL and capsular bag subluxation. Introduction: Spontaneous subluxation of the IOL and capsular bag complex after cataract surgery is a recurrent serious but rare complication. Pseudoexfoliation has been associated with this complication. Neverthe...

Purpose: To present a retrospective study of 51 eyes of 47 patients submitted to Descemet Stripping Automated Endothelial Keratoplasty. Introduction: Endotelial keratoplasty is the preferred surgical approach when treating endothelial disease. There are various indications for DSAEK. The most common indication for DSAEK is pseudophakic bullous kera...