Luís Carlos Lopes-Júnior

Universidade Federal do Espírito Santo | UFES · Health Sciences Center

Health information is particularly essential in times of pandemics in which rapid response is crucial for political and stakeholder decision-making processes, and therefore the availability of data as well as its quality analysis are necessary. This study aimed to describe the completeness and quality of the e-Sistema Único de Saúde (SUS) Health Su...

This is a systematic review protocol whose objective is to synthesize and evaluate the prevalence, composition, stability, predictors and outcomes of cancer symptom clusters in children and adolescents undergoing chemotherapy. This systematic review protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protoco...

EDITORIAL. Important advances in cancer management have been made in the beginning of the 21st century. Most of them are associated with patient care and treatment, including development of new or more precise individual therapies and molecular diagnostics, which had implicated in better outcomes and extended survivals, mostly due to personalized...

Heart disease and cancer are the main causes of morbidity and mortality worldwide. As the number of cancer survivors increases, cardiotoxicity associated with cancer treatment has become a major concern as it presents a substantial challenge in the follow-up of these patients. Here, we aimed to map the clinical indicators for cardiovascular risk in...

Uno de los principales propósitos de la Iniciativa Mundial de la OMS contra el Cáncer Infantil y el marco de trabajo CureAll Americas consiste en fortalecer los centros de excelencia y promover la formación de los recursos humanos para la salud, en especial de las enfermeras y los enfermeros de oncología pediátrica, especializados en la atención de...

The pandemic has been characterized by several waves defined by viral strains responsible for the predominance of infections. We aimed to analyze the mean length of hospital stay for patients with COVID-19 during the first three waves of the pandemic and its distribution according to sociodemographic and clinical variables. This retrospective study...

Background: Globally, pancreatic cancer is the seventh most common cause of cancer-related death in both sexes, accounting for 466,003 deaths and 495,773 new cases in 2020. The purpose of this study was to synthesize and evaluate evidence on the effects of omega-3 supplementation on the nutritional status of patients with pancreatic cancer. Metho...

Objective: To identify and map the available evidence on the implementation of public health policies directed at individuals with rare diseases, and to compare the implementation of these health policies between Brazil and other countries. Method: A scoping review guided by the PRISMA-ScR and JBI checklists. The search for articles was conducted i...

Exposure to situations of domestic violence during the treatment for breast cancer may compromise the treatment and quality of life of women patients, so it is essential that health professionals act in tracking this phenomenon in the approach to and care of women with breast cancer. The purpose of this study was to examine experiences of violence...

Background: Children with Special Health Care Needs (CSHCN) require greater attention from family caregivers as they present temporary or permanent physical, developmental, behavioral, or emotional issues. This demand for care generates overload and stress among family caregivers. So far, there is no study that gathers the available literature rega...

Objective: We describe the prevalence of the reported cases of sexual violence against adolescents and analyze their associated factors. Methods: A cross-sectional analytical study (n = 561) was conducted with reported data on sexual violence against adolescents in the state of Espírito Santo registered in SINAN between 2011 and 2018 to understand...

Objective: To analyze COVID-19 deaths in public hospitals in a Brazilian state, stratified by the three waves of the pandemic, and to test their association with socio-clinical variables. Methods: Observational analytical study, where 5436 deaths by COVID-19 occurred in hospitals of the public network of Espírito Santo, between 1 April 2020, and...

Objective: to present and discuss the advancement of science in symptom management through research involving oncological symptom clusters (OSC). Method: a reflective study, supported by the scientific literature on OSC. Results: five key points are crucial to advancing the science of symptom management through research involving OSC: definition...

Objetivo: apresentar e discutir sobre o avanço da ciência no manejo de sintomas por meio da pesquisa envolvendo os clusters de sintomas oncológicos (CSO). Método: estudo reflexivo, sustentado na literatura científica sobre os CSO. Resultados: cinco pontos-chave são cruciais para o avanço da ciência no manejo de sintomas por meio da pesquisa envolve...

Background: Despite the expansion of home care services (HCS) in several countries, there is still a need to systematically investigate the available evidence on the cost-effectiveness of this type of service compared to hospital care in the world, particularly for the pediatric population. Hence, we aimed to systematically synthesize and criticall...

Objective: to identify the frequency of reported cases of recurring violence against adolescents and their association with victim, violence, and aggressor characteristics. Method: cross-sectional study conducted with notified data on violence against adolescents, produced by Epidemiological Surveillance and registered in the Information System of...

Objetivo: identificar a frequência de casos notificados de violência recorrente contra adolescentes e sua associação com as características da vítima, da violência e dos agressores. Método: estudo transversal, realizado com os dados notificados de violências contra adolescentes, produzidos pela Vigilância Epidemiológica e registrados no Sistema de...

Resumen Objetivo: identificar la frecuencia de casos notificados de violencia recurrente contra adolescentes y su asociación con las características de la víctima, de la violencia y de los agresores. Método: estudio transversal, realizado con los datos notificados de violencias contra adolescentes, producidos por la Vigilancia Epidemiológica y regi...

Objective: To evaluate the completeness and consistency of data from hospital-based cancer registries (HCRs) in a Brazilian state. Methods: This retrospective descriptive study was based on secondary data from an HCR in the state of Espírito Santo (ES) between 2010 and 2017. The data were collected between August and November 2020 by the ES Stat...

Background: In oncology, the prevalence of symptoms is preferentially analyzed in isolation instead of being considered in clusters. However, clinical practice shows that symptoms rarely occur separately but rather form clusters that share common underlying mechanisms in terms of intensity and severity, creating a synergistic effect among them, whi...

Background: Cancer is marked by disruption of circadian rhythms, resulting in an exacerbation of cancer symptom clusters, which may affect the response to treatment and the patient's quality of life. We aimed to investigate basal sAA activity, salivary cortisol and cytokine levels in osteosarcoma pediatric patients at 4 points of a day of hospitali...

Background: Although most neoplasms result from complex interactions between the individual’s genome and the environment, a percentage of cases is particularly due to inherited alterations that confer a greater predisposition to the development of tumors. Hereditary Neoplastic Syn- dromes have a high psychosocial and economic burden, in addition to...

Introduction: Nurses comprise the largest group of health workers globally and are essential to the provision of care necessary for delivering curative therapy to children with cancer. In high-income countries, previous studies of the nurse workforce have shown an association between patient morbidity and mortality and nursing-related factors such...

Cursando com elevado ônus biopsicossocial e econômico, a pandemia impôs, entre outras, a necessidade de um consolidado mecanismo de Vigilância em Saúde nos sistemas de saúde. Objetivou-se relatar a experiência vivenciada na vigilância dos casos de internações por COVID-19 e reportar seu monitoramento no estado do Espírito Santo. Relato de experiênc...

Objective: To analyze the survival of patients hospitalized with COVID-19 and its associated factors. Methods: Retrospective study of survival analysis in individuals notified and hospitalized with COVID-19 in the state of Espírito Santo, Brazil. As data source, the reports of hospitalized patients in the period from 1 March 2020, to 31 July 2021 w...

Although the importance of genetics and genomics in nursing education has been widely recognized, surveys carried out in several countries show that these subjects are still limited in nursing undergraduate programs. In Latin America, the teaching of genetics and genomics in nursing programs has never been previously documented. Considering this sc...

Introduction Outpatient care for children and adolescents with chronic conditions needs to be continuous and programmed, encompassing comprehensive care, with periodically scheduled consul- tations, exams, and procedures, to promote quality of life and reduce mortality. In the con- text of the new coronavirus pandemic, however, outpatient care for...

Objective To compare the health-related quality of life (HRQoL) scores of children and adolescents hospitalized with cancer who had and did not have fatigue and to correlate fatigue and HRQoL. Method This is a cross-sectional study carried out for 48 months in the onco-hematology sector of a public hospital located in the interior of São Paulo, wi...

Objetivo: Comparar os escores de qualidade de vida relacionada à saúde (QVRS) de crianças e adolescentes hospitalizados com câncer que apresentaram e não apresentaram fadiga e correlacionar fadiga e QVRS. Método: Estudo transversal realizado durante 48 meses no setor de onco-hematologia de hospital público localizado no interior paulista, com 63 cr...

Objective: To reflect on advanced practice nursing in Primary Health Care considering the complexity of the Brazilian health system. Methods: Reflective study, based on the document "Expanding the role of nurses in Primary Health Care" and anchored in the literature and critical analysis of the authors. Results: Due to the complexity of the Un...

Objetivo: Refletir sobre a enfermagem de prática avançada na Atenção Primária à Saúde considerando a complexidade do sistema de saúde brasileiro. Métodos: Estudo reflexivo, fundamentado no documento “Ampliação do papel dos enfermeiros na Atenção Primária à Saúde” e ancorado na literatura e análise crítica dos autores. Resultados: Pela complexidade...

Introduction: Palliative care is an approach that improves patients' quality of life and their families when they face problems inherent to a life-threatening illness. In the current scenario where breast cancer ranks first among the most common types of cancer in women, research has revealed little control by these patients over the symptoms of th...

Objetivo: Identificar e sintetizar as evidências oriundas de ensaios clínicos randomizados que avaliaram os efeitos da musicoterapia sobre os sintomas de ansiedade e de depressão em adultos com transtornos mentais. Métodos: Revisão sistemática guiada pelo protocolo Preferred Reporting Items for Systematic Reviews and Meta-Analysis. A busca dos arti...

Objective: To identify and synthesize evidence from randomized clinical trials that assessed the effects of music therapy on anxiety and depression symptoms in adults with mental disorders. Methods: This is a systematic review guided by the Preferred Reporting Items for Systematic Reviews and Meta- Analysis protocol. The search for articles in the...

Objective: To assess the microbiological quality of pasteurized human milk from a Human Milk Bank in the State of São Paulo. Methods: This is a descriptive study conducted with 29 pasteurized expressed human milk (PEHM) samples obtained between July 2015 and March 2016 by assessing titratable acidity records as well as quantifying heterotrophic mic...

The extensive investment and development of research in molecular biology in the last decades, mainly after the completion of the Human Genome Project, has raised many expectations regarding its impact on Precision-Medicine Era. To meet the new demands for care, it is necessary that the omics sciences be integrated into nursing practice, especially...

Introdução: com a conjuntura atual do sarampo no Brasil, além da queda acentuada da cobertura vacinal em âmbito nacional, faz-se necessário pensar sobre as formas de intervir frente a tantos desafios, compreendendo que a ampliação da cobertura vacinal é a forma mais efetiva e segura para o controle de doenças infectocontagiosas. Objetivo: analisar...

Introduction: with the current situation of measles outbreak in Brazil and the sharp drop in immunization coverage nationwide, it is necessary to think about ways to intervene in the face of so many difficulties, since the expansion of immunization coverage is the most effective and safe for the control of infectious diseases. Objective: to analyze...

Background: One of the most recent concerns of this pandemic regards the role of schools reopening in disease transmission, as well as the impact of keeping schools closed. While school reopening seems critical for the education and mental health of children, adolescents, and adults, so far the literature has not systematically reached a consensus...

Background: Down syndrome is the most frequent genetic cause of intellectual disability, with an estimated birth prevalence of 14 per 10,000 live births. In Brazil, statistical data on the occurrence of babies born with Down syndrome remain unclear. We aimed to estimate the occurrence of Down syndrome between 2012 and 2018, and to observe its assoc...

The Unified Health System (SUS) has the National Immunization Program (NIP), coordinated by the Ministry of Health, which has been consolidating itself as one of the most relevant public health interventions in the world. Created in 1973, in its 46-year trajectory, the PNI is characterized as an efficient public policy, increasingly impacting the p...

Objective: To discuss the evolution of research in cancer psychoneuroimmunology, the advances in the management of neuropsychological symptom clusters and their interface with mid-range theories, and practical applications in Nursing. Method: This is a theoretical-reflective study anchored in recent literature, as well as in the critical analysi...

Objetivo: Discutir a evolução das pesquisas em psiconeuroimunologia do câncer, os avanços no manejo dos clusters de sintomas neuropsicológicos e sua interface com teorias de médio alcance e aplicações práticas pela Enfermagem. Método: Estudo teórico- reflexivo ancorado em literatura recente, bem como na análise crítica dos autores. Resultados: Este...

Available at SSRN: https://ssrn.com/abstract=3897179 DOI: http://dx.doi.org/10.2139/ssrn.3897179

EDITORIAL. Globalmente, as Doenças Crônicas Não Transmissíveis (DCNT) transpõem-se como as principais responsáveis pelo acometimento e óbito da população. Segundo alertas da Organização Mundial da Saúde (OMS), da Organização das Nações Unidas (ONU), e do Banco Mundial (BM), além de outros organismos internacionais, as DCNT constituem numa ameaça gl...

Recent epidemiological evidence has linked circadian disruptions to several chronic conditions, including cancer. Experimental studies and clinical trials with cancer patients have shown that dysregulation of circadian rhythms acts as an important inducer and promoter of cancer, and/or exacerbating cancer symptom clusters and consequently decreasin...

Nurses have an educational background particularly suited to the growing challenges of the 21st century, characterized by an accelerated demographic transition, accompanied by a scenario of triple disease burden: 1) the unsurpassed agenda for infectious diseases; 2) the increase in deaths attributable to external causes; and 3) the predominance of...

Objetivo: Avaliar a efetividade de terapias complementares no manejo dos clusters de sintomas em crianças e adolescentes com câncer em cuidados paliativos. Método: Revisão sistemática guiada pelo Preferred Reporting Items for Systematic Reviews and Meta-Analyses, com acesso às bases de dados MEDLINE, Web of Science, Central Cochrane e PsycINFO. A...

Objective: To evaluate the effectiveness of complementary therapies in the management of symptom clusters in children and adolescents with cancer undergoing palliative care. Method: Systematic review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, resorting to the databases MEDLINE, Web of Science, Central Cochr...

Objetivo: compartilhar e refletir sobre a experiência de implementação do Acolhimento com Classificação de Risco como dispositivo de gestão em uma Unidade Básica de Saúde. Método: Estudo descritivo-reflexivo na modalidade relato de experiência, sobre a implementação de um plano de intervenção em uma Unidade Básica de Saúde, alicerçado no pensar ref...

Objective: to describe and discussing the challenges of SUS in the current scenario and also the role of Health Surveillance in the context of the new coronavirus pandemic. Method: Theoretical essay anchored in national and international scientific literature, plus authors' critical analysis. Based on the theoretical construction on reflective thin...

Objetivo: descrever e discutir sobre os desafios do SUS na atualidade e a atuação da Vigilância em Saúde no contexto da pandemia do novo coronavírus. Método: Ensaio teórico ancorado na literatura científica nacional e internacional, acrescida da análise crítica dos autores. Com base na construção teórica sobre o pensar reflexivo, foram abordados,...

Lopes-Júnior LC. Medicina genômica e a Enfermagem. In: Associação Brasileira de Enfermagem; Bresciani HR, Martini JG, Mai LD, organizadoras. PROENF Programa de Atualização em Enfermagem: Saúde do Adulto: Ciclo 16. Porto Alegre: Artmed Panamericana; 2021. p. 10–62. v. 1. https://doi.org/10.5935/978-65-5848-215-4.C0003

Objetivo: refletir sobre a importância dos registros de câncer para a Vigilância em Saúde Pública. Método: Trata-se de um ensaio teórico, cuja fundamentação baseia-se na formulação discursiva acerca da temática, sustentado na literatura científica nacional e internacional e análise crítica do autor. Utilizou-se como referencial teórico o pensar ref...

Introdução: Na América Latina, as lacunas preexistentes nos sistemas de saúde com relação direta às iniquidades sociais trazem à tona a importância de refletir sobre o papel da Atenção Primária à Saúde em trazer respostas mais efetivas e sustentáveis em tempos de pandemia. Objetivos: contextualizar os sistemas de saúde na América Latina e discutir...

Introducción: En América Latina, las brechas preexistentes en los sistemas de salud con relación directa con las inequidades sociales ponen de manifiesto la importancia de reflexionar sobre el papel de la Atención Primaria de Salud para brindar respuestas más efectivas y sostenibles en tiempos de pandemia. Objetivos: contextualizar los sistemas de...

Objective: To summarize and critically analyze the literature on potential biomarkers associated with clinical outcomes in the postoperative cardiac surgery period in infants and children under intensive care. Methods: Integrative review, whose search was carried out in September and December 2019 in the databases MEDLINE, ISI Web of Knowledge, Co...

Objective: To summarize and critically analyze the literature on potential biomarkers associated with clinical outcomes in the postoperative cardiac surgery period in infants and children under intensive care. Methods: Integrative review, whose search was carried out in September and December 2019 in the databases MEDLINE, ISI Web of Knowledge, Coc...

EDITORIAL: O termo "Psiconeuroimunologia" (PNI) emergiu na década de 1970 com o trabalho de Robert Ader (1) e, a partir de então, difundiu-se como expressão para designar o campo da ciência que estuda de modo interdisciplinar a interação entre os processos psicológicos e as fun-ções neurológica, endócrina e imunológica, e como essa interação in uen...

EDITORIAL: The term “Psychoneuroimmunology” (PNI) has emerged in 1970 with the study by Robert Ader(1) and, since that, it has been promot- ed as an expression to designate the field of the science that study in an interdisciplinary manner the interaction between the psychological process and neural, endocrine, and immune function, as well as how...

After December 2019, when the first cases of the then disease caused by a recently identified coronavirus (now named Sars-CoV-2, severe acute respiratory syndrome coronavirus 2) were reported in Wuhan, China, the disease caused by the new coronavirus (coronavirus disease 2019 – COVID-19) emerged officially as a pandemic declared by the World Health...

Objective To evaluate evidence from randomised controlled trials and non-randomised controlled trials on the effectiveness of hospital clowns for a range of symptom clusters in children and adolescents admitted to hospital with acute and chronic conditions. Design Systematic review of randomised and non-randomised controlled trials. Data sources...

Background: Colitis-associated cancer (CAC) accounts for 2%-3% of colorectal cancer (CRC) cases preceded by inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis. Intestinal microbiota has been reported to play a central role in the pathogenesis of IBD and CAC. Recently, numerous prebiotics and probiotics have being inve...

Na sociedade brasileira, as questões econômicas, sociais e ambientais são regulamentadas por políticas públicas , as quais podem ser entendidas como um dispositivo que revela o dever do Estado em garantir, no âmbito da saúde, a resolutividade dos serviços, o acesso oportuno à assistência e ao cuidado. Políticas públicas têm no cerne de sua criação...

Mundialmente há uma crescente demanda pública por discussões mais aprofundadas no campo da Medicina Integrativa. No Brasil, ainda são escassos os espaços para discussão e aprofundamento das Práticas Integrativas e Complementares (PIC). Objetivou-se refletir sobre as perspectivas e desafios futuros para a Política Nacional de Práticas Integrativas e...

RESUMO É premente avançar na análise dos problemas e desafios do SUS, buscando superar o debate meramente ideológico, de modo a identificar os nós críticos que impedem a consolidação e avanço do sistema. Objetivou-se refletir sobre os desafios para consolidação do Sistema Único de Saúde enquanto sistema de saúde universal. Trata-se de um ensaio teó...

O câncer cursa com elevado ônus psicossocial e econômico e é considerado um importante problema de saúde pública global. Objetivou-se refletir acerca da evolução da atenção oncológica no âmbito do Sistema Único de Saúde (SUS). Trata-se de um ensaio teórico ancorado na literatura científica nacional e internacional. Dentre as principais normativas n...

O interesse pelas doenças raras tem aumentado nos últimos anos, fato que se atribui pelo reconhecimento de que as mesmas representam um problema de saúde pública global. Objetivou-se refletir sobre os avanços e desafios para a operacionalização da Política Nacional de Atenção Integral às Pessoas com Doenças Raras no âmbito do Sistema Único de Saúde...

Os registros de câncer são essenciais para subsidiar o monitoramento e a avaliação de ações para o controle das neoplasias. Objetivou-se apresentar e refletir sobre a importância dos registros de câncer a partir do sistema integrador dos Registros Hospitalares de Câncer do Estado do Espírito Santo. Trata-se de um ensaio teórico de cunho reflexivo....