Lucile Dupin

French National Centre for Scientific Research | CNRS

Perception and action are based on cerebral spatial representations of the body and the external world. However, spatial representations differ from the physical characteristics of body and external space (e.g. objects). It remains unclear whether these discrepancies are related to functional requirements of action and are shared between different...

Body representation distortion (BRD) is a core criterion of Anorexia Nervosa (AN), and is usually assessed subjectively, focusing on body shape. We aimed to develop a new assessment to evaluate body representation independently from socially-mediated body image, on a body part with low emotional salience (hands). In a monocentric open label pilot s...

Perception of space has puzzled scientists since antiquity, and is among the foundational questions of scientific psychology. Classical “local sign” theories assert that perception of spatial extent ultimately derives from efferent signals specifying the intensity of motor commands. Everyday cases of self-touch, such as stroking the left forearm wi...

Classical accounts of spatial perception are based either on the topological layout of sensory receptors, or on implicit spatial information provided by motor commands. In everyday self-touch, as when stroking the left arm with the right hand, these elements are inextricably linked, meaning that tactile and motor contributions to spatial perception...

Locating a tactile stimulus on the body seems effortless and straightforward. However, the perceived location of a tactile stimulation can differ from its physical location. Tactile mislocalizations can depend on the timing of successive stimulations, tactile motion mechanisms, or processes that ‘‘remap’’ stimuli from skin locations to external spa...

During the haptic exploration of a planar surface, slight resistances against the hand's movement are illusorily perceived as asperities (bumps) in the surface. If the surface being touched is one's own skin, an actual bump would also produce increased tactile pressure from the moving finger onto the skin. We investigated how kinaesthetic and tacti...

Background We developed five tablet-based tasks (applications) to measure multiple components of manual dexterity. Aim: to test reliability and validity of tablet-based dexterity measures in healthy participants. Methods Tasks included: (1) Finger recognition to assess mental rotation capacity. The subject taps with the finger indicated on a virtu...

Current classification systems use the terms “catatonia” and “psychomotor phenomena” as mere a-theoretical descriptors, forgetting about their theoretical embedment. This was the source of misunderstandings among clinicians and researchers of the European collaboration on movement and sensorimotor/psychomotor functioning in schizophrenia and other...

During active movement, there is normally a tight relation between motor command and sensory representation about the resulting spatial displacement of the body. Indeed, some theories of space perception emphasize the topographic layout of sensory receptor surfaces, while others emphasize implicit spatial information provided by the intensity of mo...

Perception of space has puzzled scientists since antiquity and is among the foundational questions of scientific psychology. Classical “local sign” theories assert that perception of spatial extent ultimately derives from efferent signals specifying the intensity of motor commands. Everyday cases of self-touch, such as stroking the left forearm wit...

Over the last three decades, movement disorder as well as sensorimotor and psychomotor functioning in schizophrenia (SZ) and other psychoses has gained greater scientific and clinical relevance as an intrinsic component of the disease process of psychotic illness; this extends to early psychosis prediction, early detection of motor side effects of...

Background Neural information processing is subject to noise and this leads to variability in neural firing and behavior. Schizophrenia has been associated with both more variable motor control and impaired cortical inhibition, which is crucial for excitatory/inhibitory balance in neural commands. Hypothesis In this study, we hypothesized that imp...

Autism spectrum disorder (ASD) and schizophrenia (SCZ) are neurodevelopmental disorders with partly overlapping clinical phenotypes including sensorimotor impairments. However, direct comparative studies on sensorimotor control across these two disorders are lacking. We set out to compare visuomotor upper limb impairment, quantitatively, in ASD and...

Impairments in attentional, working memory and sensorimotor processing have been consistently reported in schizophrenia. However, the interaction between cognitive and sensorimotor impairments and the underlying neural mechanisms remains largely uncharted. We hypothesized that altered attentional processing in patients with schizophrenia, probed th...

Video S1. Annotated Video Showing the Events of a Single Illustrative Trial, Related to STAR Methods

The ability to infer from uncertain information is impaired in schizophrenia and is associated with hallucinations and false beliefs. The accumulation of information is a key process for generating a predictive internal model, which statistically estimates an outcome from a specific situation. This study examines if updating the predictive model by...

Abstract The shape of objects is typically identified through active touch. The accrual of spatial information by the hand over time requires the continuous integration of tactile and movement information. Sensory inputs arising from one single sensory source gives rise to an infinite number of possible touched locations in space. This observation...

The extraction of spatial information by touch often involves exploratory movements, with tactile and kinesthetic signals combined to construct a spatial haptic percept. However, the body has many tactile sensory surfaces that can move independently, giving rise to the source binding problem: when there are multiple tactile signals originating from...

Significance When we actively explore objects by touch, the brain receives two types of signals, tactile sensory inputs and signals about the exploratory movement, which must be combined to perceive the shape and location of objects in space. Whereas these signals usually come from the same body part, we have developed a technique to separate them,...

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 8619, pp. 427-429

When we move a finger along an object with the eyes closed, we can sometimes identify its shape, size and orientation in space. However, the information available at every moment only includes the sensation corresponding to a small part of the object. To perceive the spatial properties of the entire object the brain must match the information about...

Perceiving three-dimensional object motion while moving through the world is hard: not only must optic flow be segmented and parallax resolved into shape and motion, but also observer motion needs to be taken into account in order to perceive absolute, rather than observer-relative motion. In order to simplify the last step, it has recently been su...

In vision, spatial constancy is the phenomenon that when our eyes or body move, we perceive objects in an external or spatiotopic reference frame, independent of our own movement, even though visual information is initially retinotopic. Spatial constancy seems to require some sort of compensation of retinotopic signals to take into account the obse...

How does a moving observer perceive the motion of 3D objects in an external reference frame? Even in the case of a stationary observer, one can perceive object motion either by estimating the movements of each object independently or by using the heuristic of considering the background as stationary [Rushton and Warren, 2005 Current Biology 15(14)...