Lucía Simón Vicente

• Researcher at Universida Rey Juan Carlos

Background Thermoregulation is critical for preventing hyperthermia during physical activity. In Huntington's disease (HD), research on possible thermoregulatory alterations has received little attention. Objectives We aimed to investigate and compare skin temperature differences before and after exercise between HD patients and healthy controls....

Introduction: Despite the wealth of evidence suggesting a protective role of lifestyle factors on Huntington's disease (HD) onset and progression, their association with mortality has not been extensively studied. The aim of this study was to examine whether lifestyle factors such as caffeine and alcohol consumption, smoking, physical activity lev...

Background/Objectives: Huntington’s disease (HD) is a neurodegenerative movement disorder associated with significant disability and impairment of Activities of Daily Living (ADLs). The impact of upper limb disability on quality of life (QoL) and its influence on ADLs is not well known yet. The aim of this study was to describe the manipulative dex...

Background: Virtual Reality (VR) uses computer technology to create a simulated environment. VR is a growing technology with promising extensive applications in different areas such as Medicine, entertainment, sports, gaming, and simulation. However, information about VR side effects is still limited. We aimed to identify the most frequent physica...

Background Motor impairment in Huntington´s Disease (HD) includes chorea, bradykinesia, dystonia and rigidity, causing upper extremity (UE) impairments that make the performance of manipulative, and fine motor activities difficult. As the disease progresses, this symptomatology leads to a loss of independence in activities of daily living (ADLs)....

Introduction Despite the wealth of evidence suggesting a protective role of lifestyle factors on Huntington’s disease (HD) onset and progression, their association with mortality has not been extensively studied. Aims To study whether lifestyle factors such as caffeine and alcohol consumption, smoking, physical activity level, and Mediterranean di...

Background Sarcopenia is defined by low levels of muscle strength, muscle quantity/quality, and, physical performance (1). Although sarcopenia in clinical cases is observed in Huntington’s disease (HD) the clinical diagnosis is still challenging. The Consensus 20191 recommends 2 tools for early identification of cases at risk: Strength, assistance...

Introduction: Huntington´s disease (HD) is a rare neurodegenerative disorder. Reliable information about nutritional status, especially body composition from individuals with HD is critical for clinical care and research. The ease of application and portability of multiple frequencies bioelectrical impedance analysis (mfBIA) make it an attractive t...

Background: The evaluation of motor impairment in Parkinson's disease (PD) is mainly assessed with the motor subdomain of the Unified Parkinson's Disease Rating scale (UPDRS part III) and, lately, with the MDS-UPDRS part III. To optimize efforts and special needs during specific circumstances in clinical practice, we sought to identify the most se...

Health professionals have been one of the groups most affected by the SARS-CoV-2 virus. Currently, there is little scientific evidence on the similarities and differences between COVID-19 infection and the development of long COVID in primary care (PC) workers. Therefore, it is necessary to analyse their clinical and epidemiological profiles in dep...

Introduction Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor dysfunction, cognitive impairment, and psychiatric disorders. These symptoms cause functional limitations in occupational performance. This study aimed to describe the difficulties in self-care, productivity, and leisure activities and...

Huntington’s disease (HD) is an autosomal dominant progressive brain disorder, caused by a pathological expansion of a CAG repeat that encodes the huntingtin gene. This genetic neurodegenerative rare disease is characterized by cognitive, motor, and neuropsychiatric manifestations. The aim of the treatment is symptomatic and addresses the hyperkine...

Breast cancer (BC) is the most common cancer diagnosis with the highest mortality rate worldwide. The aim of this study was to identify factors related to depression and anxiety in mastectomized women BC survivors. A cross-sectional study was conducted with a sample of 198 women diagnosed with BC aged 30–80 years in Mexico. Depression and anxiety w...

Persistent COVID-19 condition includes a wide variety of symptoms and health problems of indeterminate duration. The present study examined the sociodemographic and clinical characteristics of the population with Long COVID seen in Primary Care using a questionnaire based on the existing scientific literature. It was an observational and descriptiv...

(1) Background: Quality of life assessment is a critical aspect of breast cancer patient outcomes, as diagnosis, prognosis and treatment can have a major impact on quality of life. The aim of this study was to describe the characteristics of the sample and to verify the relationship between quality of life (QOL) in women diagnosed with breast cance...

Accelerometers can estimate the intensity, frequency, and duration of physical activity in healthy adults. Although thresholds to distinguish varying levels of activity intensity using the Actigraph wGT3X-B have been established for the general population, their accuracy for Huntington’s disease (HD) is unknown. We aimed to define and cross-validat...

Background Consumer and research activity monitors have become popular because of their ability to quantify energy expenditure (EE) in free-living conditions in a cost-efficient way. However, there is not research on the validity of this devices in people with Huntington’s disease (HD). Aims To determine the accuracy of the Actigraph and Fitbit co...

Rationale Risk for or established malnutrition is frequent in Huntington´s disease (HD), accompanied by functional limitations, increased morbidity, and mortality. Phase angle is associate with changes in the structure of the cell membrane of soft tissue mass, alterations in fluid balance and it has been shown as an indicator of prognostic clinic i...

Rationale Sarcopenia is associated with frailty, and dependence in older patients. Mediterranean Diet (MeDi) is one of the best models for healthy eating, associated with a better life quality in Huntington´s disease (HD). Targeted physical activity intervention has been identified as beneficial in several health disorders, including sarcopenia. Ou...

Background Huntington’s Disease (HD) is a neurodegenerative disorder characterized by cognitive, motor, and neuropsychiatric manifestations. Oxytocin is a neuropeptide studied for its role as a neuromodulator regulating multiple behaviors linked to social cognition. Genetic variation of oxytocin receptor (OXTR) might interact in the etiology and de...

Background Thermoregulation is the maintenance of a relatively constant core body temperature which influences tolerance to physical activity. Brown adipose tissue, skeletal muscle, and hypothalamus are components involved in this process. Transgenic animal models of Huntington’s disease (HD) have provided informative models of thermoregulatory dis...

BACKGROUND Among the different clinical manifestations, weight loss and energy balance (EB) deficit have been described frequently in Huntington's disease (HD), contributing to HD progression. To develop a therapeutic approach to prevent weight loss and EB deficit in HD, we will conduct a study designed to validate the usefulness of accelerometers...

Background Virtual Reality (VR) uses computer technology to create a simulated environment. VR is a growing technology with promising extensive applications in different areas such as Medicine, entertainment, sports, gaming, and simulation. However, information about VR side effects is still limited. We aimed to identify the most frequent physical...

Background Body composition is a strong indicator of nutritional and health status. Dual energy X-ray absorptiometry (DXA), multifrecuency bioelectrical impedance analysis (BIA), anthropometry and, skinfolds are non invasive methods to assess body composition with different levels of reliability. The validity of anthropometric and skinfolds to esti...

Introducción: La evaluación de las actividades y la participación son dos elementos claves en la funcionalidad del miembro superior (MS) para el proceso de neurorrehabilitación. Conocer la evaluación que realizan los/as profesionales de la terapia ocupacional puede ser de utilidad para la rehabilitación. Por tanto, el objetivo principal del estudio...