I'm looking for collaborators on my PhD project. I work on multi-omic imputation of missing values in proteomics.
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
I'm trying to develop missig value imputation algorithms on Mass-Spectrum proteomics. The aim is to leverages the available information at RNA level, to refine our imputation method at peptide level. We would like to develop an algorithm robust to MAR and MNAR case, as many missing values are due to low abundace peptides.
In proteomic differential analysis, FDR control is often performed through a multiple test correction (i.e., the adjustment of the original p-values). In this protocol, we apply a recent and alternative method, based on so-called knockoff filters. It shares interesting conceptual similarities with the target-decoy competition procedure, classically...