Luca Dan Serbanati

• PhD in Computer Science, BSc in Mathematics
• Professor Emeritus at Universitatea Națională de Știință și Tehnologie Politehnica București

Background The digital transformation is a technological revolution that now penetrates all aspects of society, including health and care systems. To digitalize business processes in health and care, new concepts and innovative solutions are needed. Health is a self-evident concept yet, at the same time, it is extremely elusive because no precise d...

Digital ecosystems are considered socio-technical clusters of adaptive applications with different levels of context awareness, adaptability, and autonomy. Applications from a digital ecosystem must solve concrete problems but have to be computationally efficient, it will have to find a balance between the freedom of a system to self-adapt and the...

EHR 2.0 is an evolution of current Electronic Health Records (EHR) which provides an intelligent support for all healthcare providers and patients in the National Health System with the benefit of improving the quality of care and increasing patient involvement in the health care and prevention process. At the center of the EHR 2.0 the paper puts t...

The paper presents the prototype of a Personal Health System (PHS) realized during the Smart Health 2.0 Project. This implementation, called 'LiSE', represents an evolution with respect to the Citizen's Personal Notebook, introduced and specified by the EHR Italian regulations. The PHR provides some features that simplify the relationships between...

An architecture for integrating legacy applications into the Romanian Health Information System platform is proposed. Such an integration is needed because a lack of interoperability between legacy medical applications and the Health Information Platform continues to exist. To solve the integration problem and create a true Unique Integrated Health...

The computational difficulty of DNA motif sequence finding algorithms is a well studied problem. One of the most promising directions in dealing with the challenges of a huge possible solution space are heuristic based methods. However, although there are various alternatives based on a stochastical model, there are few studies that look at differe...

This paper proposes a software model based on service-oriented architecture (SOA) for remote rehabilitation of patients with cardiovascular disease (CVD). The chosen approach ensures an efficient and easier interaction between both health providers and patients enrolled in the cardiac rehabilitation programs (CRP) by excluding the attendance at fac...

Contemporary, most modern electronic healthcare record systems (EHR-S) have service oriented architectures. In the paper our approach to developing an advanced regional EHR-S that supports not only the patient's care process due to individual care providers but also the management of teams in interdisciplinary team-based care processes is presented...

SmartFSE in course of development in Sicily Region is a longitudinal EHR based on an IT infrastructure that supports the shift from organization-centric to patient-centric model of healthcare service delivery. In order to facilitate collaborative, multidisciplinary and cross-organizational healthcare delivery processes, SmartFSE provides e-services...

The context concept that healthcare applications use is extended and refined as a multifaceted collection of information about the situation in which an entity, be it person or application, is. This information may reshape the interpretation that other entities involved in interactions with that entity give to the entity state or behavior. Studying...

The nowadays pervasive mobile devices embed among one or two cameras a multitude of sensors facilitating the capture of the surrounding context and thus the picture visual content is enriched with the additional metadata. Moreover, the digital storage of the pictures either on a personal device or by the use of an online photo management and sharin...

There are many reasons to reflect upon the importance of paradigms in healthcare, their explicit use in health system restructuring and the possibility to anticipate the health field evolution with paradigms. For instance, it is known that an improving or restructuring strategy is needed to adapt health systems to major changes in the way of thinki...

Questo articolo presenta alcuni paradigmi recentemente trasferiti dal business alla sanità o venuti alla gala dalle esigenze del mondo della sanità e altri che sono già presenti nella sanità elettronica come echi di alcuni paradigmi nell’ingegneria del software. In finale si propongono altri due paradigmi dell’ingegneria del software che nel futuro...

The paper proposes a recommendation mechanism to enhance the managerial training in project-oriented organizations (POOs). The mechanism is presented within the framework of an innovative system used to provide support to POOs during the acquisition and implementation of training services. The recommender engine has, as inputs, the knowledge gaps o...

The paper extracts proven principles from software engineering to be applied in the field of prevention and wellness preserving. For instance, the concern-oriented partitioning principle could give support to analysis and design of healthcare information systems. Results of such an approach are multifaceted systems that integrate all stakeholders’...

The purpose of this paper is to provide a framework for the e-health application of the future. Starting from a state-of-the-art in e-health research, standards and projects, a new conceptual model based on the digital ecosystem paradigm and a multi agent system implementation is proposed. We call agentification the transition from the conceptual m...

Structurata in volume, lucrarea se adreseaza celor interesati in programarea Java, indiferent de nivelul lor intial de pregatire, oferind o baza solida de cunostinte. Daca in primul volum se trateaza notiuni de baza ale programarii orientate spre obiecte si ale limbajului Java, al doilea cuprinde notiuni avansate de programare, ca de exemplu gestiu...

In the paper an IT infrastructure for supporting the shift from organization-centric to patient-centric model of healthcare service delivery to facilitate collaborative, multidisciplinary and cross-organizational healthcare delivery processes is presented. The core of this infrastructure is an internet platform that provides e-services and promotes...

In our paper we describe our vision for an e-Health integrated solution based on the Virtual HealthCare Record (VHCR), an internet entity that communicates with the EHR and other systems of caregivers in order to capture and integrate relevant information on healthcare events occurred during the life of patients. It is built to support a broad rang...

The paper describes a new direction towards supporting a continuity of care by using the more natural and expressive paradigm of digital ecosystems. We introduce the conceptual model and architecture of the Digital Healthcare Ecosystem focusing on the reflection of the real to the virtual in healthcare followed by a “contamination” of the virtual i...

New paradigms are needed for a more natural model of the healthcare process in order to reduce the semantic gap between its representation and implementation. Starting from a patient-centric perspective and a digital ecosystem framework we develop a conceptual model of the healthcare ecosystem to lay a sound foundation and a common vocabulary for e...

The Lucania – Medici in Rete (LuMiR) project aims to support the changing environment in the Italian National Health Systems, embodying a shift from organisation-centric to patient-centric services in the Basilicata Region. The primary objective of the LuMiR project is to foster collaborative, cross-organizational and patient-centric healthcare pro...

To manage the complexity of the development of an Information System (IS) a systematic partitioning of its models is needed. In particular, the system conceptual domain construction requires a structured approach. Our research on conceptual modelling in software engineering conducted us to propose a concern-oriented analysis approach aimed to const...

The Electronic Health Record is a central, unifying component in an eHealth infrastructure. In our paper we present a model for the EHR called Virtual Health Record (Sebanati et al, 2008) (VHCR) together with its services of discovery and cooperation implemented using software agents. Having an open, decentralized architecture in mind we provide th...

The Lucania-Medici in Rete (LuMiR) project aims to support the shift from organization-centric to patient-centric healthcare in Basilicata, a region in the southern Italy. Main objective of the project is to foster collaborative, multidisciplinary and cross-organizational healthcare processes by developing and stimulating the adoption of a region-w...

Concern orientation gives us methodological tools for managing the system complexity. Separation of concerns in the aspect oriented software development (AOSD) allows architects to structure and developers to better manage complex systems by mapping the whole system in a multi-concern space and focusing one problem at a time. Certainly, there is a...

Our group has started a project aiming at the development of analysis algorithms devoted to images produced by two-dimensional electrophoresis (2-DE) for general applications in the field of proteomics. General analysis problems have been addressed, with the ultimate goal of the maximization of the "automation level" of the analysis procedure, with...

MobiDis is an information system aimed to include healthcare caregivers and consumers in a virtual healthcare organization. It provides healthcare professionals and organizations with services which can access virtual healthcare records of citizens. These services are provided when and where it is needed, while still providing timely and secure acc...

A concern-based approach to design is presented. The causal elements of human actions such as the agent’s needs, interests, desires and beliefs are considered as concerns the agent should resolve in order to reach his/her objectives. For the designer of a product many needs, interests and desires of the product stakeholders turn into his/her own co...

A concern-based approach to design is presented. The causal elements of human actions such as the agent’s needs, interests, desires and beliefs are considered as concerns the agent should resolve in order to reach his/her objectives. For the designer of a product many needs, interests and desires of the product stakeholders turn into his/her own co...

A concern-based approach to design is presented. The causal elements of human actions such as the agent’s needs, interests, desires, and beliefs are considered as concerns that the agent should resolve in order to reach his/her objectives. For a product designer, many needs, interests, and desires of the product stakeholders turn into his/her own c...

There are various, important information sources devoted to the diffusion of clinical trials, but they fail to achieve a complete coverage of clinical research. The demand for a mandatory public registration of clinical trials is emerging from different institutions, which are making efforts to develop common metadata schemas to both increase infor...

Sharing an ontology is an essential condition of achieving the stakeholders’ agreement as well as the interoperability of the applications which stakeholders use or are interested in. The paper presents a method based on a concern-oriented analysis aimed to partition the information system domain in stakeholder-oriented sub-domains. A stakeholder’s...

Sharing an ontology is an essential condition of achieving the stakeholders’ agreement as well as the interoperability of the applications which stakeholders use or are interested in. The paper presents a method based on a concern-oriented analysis aimed to partition the information system domain in stakeholder-oriented sub-domains. A stakeholder’s...

In this paper, we describe an ongoing project dedicated to kindergarten children. By invoking a narrative context, we propose to children an AR-based virtual environment within which they are expecting to learn by playing each other, as they are doing in a real context. The proposed subjects for the educational contexts are selected by the teacher,...

Background: The complexity of the clinical trial (CT) process involves high investments in the research of a new drug or procedure. To reduce costs and enhance the research quality many software products are available on the market. A need of integration and re-use of these heterogeneous products as well as a more flexible conduction of CTs is evid...

The paper introduces a method for identifying, classifying, and analyzing the concerns of the stakeholders of a business system (i.e. an enterprise). The method is useful when we are going to develop an information system (IS) in the context of a given business. Understanding and resolving these concerns allow us to more easily gather the requireme...

In order to estimate the cost of generic clinical guidelines based on telemedicine services for chronic patients, an economic model (E-DIMEM) has been defined. This model is designed to help health suppliers and managers to plan for the future. It is essentially a workflow composed by diagnosis and therapeutic activities. The cost of each workflow...

In order to estimate the cost of generic clinical guidelines based on telemedicine services for chronic patients, an economic model (E-DIMEM) has been defined. This model is designed to help health suppliers and managers to plan for the future. It is essentially a workflow composed by diagnosis and therapeutic activities. The cost of each workflow...

In the last few years, a new trend in programming centered on a new paradigmcalled aspect-oriented programming(AOP) has emerged. AOP is based on the object-orientedprogramming and introduces a new concept, the aspect. The aspects model those featuresbeing in many objects of an application may change or evolve independently one from theothers. Beca...

This new model standardizes data exchange between the various stages of a research study

The presented project, called VirtualDive, implements an educational, virtual-reality-based environment dedicated for children. The user "immersion" into the virtual underwater world permits him to interact with different fish species as well as to perturb the simulated environment conditions, such as temperature and pollution. Educational actions,...

The paper presents some results of the MobiDis project. MobiDis is an information system that includes healthcare consumers and providers in a unique, virtual organisation aimed at promoting a patient centric paradigm in healthcare. It allows logons from desktop or laptop computers, as well as wireless PDAs or tablet PCs connected to Internet. In M...

This paper presents a distributed virtual reality environment for children called EVE—Environnements Virtuels pour Enfants. The virtual environment architecture is reactive agents based. The FCM-like dynamic action planning mechanism assures agent’s adaptability to its environment changes. This virtual environment supports cooperation among members...

In the paper some results of the modelling of the clinical trial (CT) process are presented. CT research is a complex process which includes the protocol editing, its use and implementation in the CT experimentation, and the evaluation of the results. To improve the medical research, it is necessary to consider the CT research process as a whole. W...

In this paper the virtual environment, viewed as a multi-dimensional space, populated by entities which interact with each other is considered. In this universe an entity can trigger interactions with another entities or can be subject of such interactions. The environment’s dynamics is determined by the information flow between its entities. The...

In this paper the virtual environment, viewed as a multi-dimensional space, populated by entities which interact with each other is considered. In this universe an entity can trigger interactions with another entities or can be subject of such interactions. The environment's dynamics is determined by the information flow between its entities.

The main topic of our research is health care unit (HCU) reengineering. To this aim, a guideline oriented conceptual model of HCUs was developed. In order to map this conceptual model into an information system with a client-server architecture, a guideline server is needed. The guideline concept and its life cycle are introduced and the main funct...

The first step in understanding information systems in health care units (HCUs) is to develop a conceptual model of HCU able to gather data and knowledge used by the management staff in order to plan, execute, control and evaluate the patient care process. An approach to HCU management modelling is presented in the paper. Our approach is centred on...

In this paper we describe how virtual hospitalization supports services and healthcare units and facilitates their integration. In order to implement the virtual hospitalization, we need to define, as first steps: the architectural approach to model health information systems; a replica of the real world in the computer. The first application of a...

A conceptual model of a health care structure is described. The management of protocols viewed as structured, flexible, and coherent descriptions of activities aimed to solve specific problems in the system is the kernel of the model. A global approach to the protocols is proposed. Each protocol is modeled from two points of view: the nature of the...

Published in 1992 by Prentice Hall, this groundbreaking book provides a unifying approach to software engineering offering insights and frameworks that remain relevant today, The book delves into the software process which is analyzed through its components: objects, activities, agents, tools, and business rules. New concepts are introduced and a f...

A system for communication protocol validation is presented. The inputs of the system are protocol descriptions that fit within the framework of the ISO Open Systems Interconnections Reference Model. These inputs include protocols used to coordinate parallel processes in applications with distributed control. The protocol is a set of rules that gov...

This paper sets out to classify the most frequently encountered syntax oriented data processings, to introduce models for these processings, as well as solutions for their implementation.

Based on a theoretical approach, we tried to implement a system for assistance to a programmer during the most difficult phase of the programming activity: software design. As we carried out the system project, it become apparent that the system could encompass more than just program design. In the paper, the main ideas of the theoretical approach...