
Luc Valere Codjo BrunUniversity of Parakou | UP · Medical School
Luc Valere Codjo Brun
MD pathologist
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17
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Publications
Publications (17)
Evolutionary medicine (or Darwinian medicine) is considered a branch of medicine and modern biology seeking to understand the mechanisms causing the onset of diseases and their evolution (and intricacy) over time. By examining the evolutionary processes of the human species, infectious agents, carcinogenic factors and the environment, it is thus po...
Introduction: Cervical cancer is more fre- quent in women living with HIV. This study sought to determine the prevalence and identify factors associated with precance- rous cervical lesions in women living with HIV in Parakou, Benin. Methods: This was a prospective cross-sectional study with des- criptive and analytical purposes. Data collection wa...
Background:
The diagnosis of the neglected tropical skin and soft tissue disease Buruli ulcer (BU) is made on clinical and epidemiological grounds, after which treatment with BU-specific antibiotics is initiated empirically. Given the current decline in BU incidence, clinical expertise in the recognition of BU is likely to wane and laboratory conf...
Background
Basidiobolomycosis is a rare subcutaneous mycosis, which can be mistaken for several other diseases, such as soft tissue tumors, lymphoma, or Buruli ulcer in the preulcerative stage. Microbiological confirmation by PCR for Basidiobolus ranarum and culture yield the most specific diagnosis, yet they are not widely available in endemic are...
Background:
An original case of incomplete (and reasonably fatal) human trepanation is described in this short paper. The diagnosis was made on the cremated remains of a young adult individual who died in Rome, Italy during the 2nd century AD.
Clinical presentation:
The trepanation was incomplete, as death occurred quickly due to vascular lesion...
Abstract Introduction: GATA6 is a transcription factor which has role in the induction of cell differentiation genes and the maintenance of the differentiated state of epithelial cells. GATA6 expression is lost in neoplastic ovarian epithelia cells and in ovarian carcinoma leading to abnormal nuclear morphology characteristic of most cancer cells....
Introduction : Les personnes vivant avec le virus de l’immunodéficience humaine (PVVIH) sont souvent candidates à des infections opportunistes et aux cancers. Les femmes porteuses de VIH meurent fréquemment de cancers gynécologiques provoqués par la destruction des protéines nucléaires lamines A/C par le virus, ou leur inhibition par certains trait...
Background: it's well known that HIV-infected women have high risk for precancerous lesions of uterine cervix. This survey aimed to determine the prevalence of SILs among HIV-infected women followed-up in a district hospital at Parakou in Benin.
Methods: From January 1st to May 31st we screened 179 consecutives non-pregnant HIV-infected women acces...
Introduction : L'Ulcère de Buruli (UB), causée par le Mycobacterium ulcerans, détruit la peau et les tissus mous. Au Bénin, l'UB représente la deuxième mycobactériose après la tuberculose (1). Sa prise en charge repose sur la biantibiothérapie à la streptomycine et la Rifampicine associée ou non à la chirurgie. Le but de cette étude était de décrir...
Introduction : L'Ulcère de Buruli (UB), causée par le Mycobacterium ulcerans, détruit la peau et les tissus mous. Au Bénin, l'UB représente la deuxième mycobactériose après la tuberculose (1). Sa prise en charge repose sur la biantibiothérapie à la streptomycine et la Rifampicine associée ou non à la chirurgie. Le but de cette étude était de décrir...