Luay Thanoon Younis

Universiti Teknologi MARA | UiTM · Centre of Studies for Periodontology

Objectives: To formulate and measure the cytotoxicity level of organic myrrh toothpaste. Materials and Methods: Myrrh extract was prepared by the freeze drying process. Toothpaste was formulated by mixing specified amounts of myrrh extract, hydroxypropyl methylcellulose (HPMC) polymer, sodium lauryl sulphate (SLS), mint, and sucralose with deionize...

Alveolar ridge loss is a physiologic consequence of tooth extraction. Often, this event causes compromised feasibility of implant placement, prosthetic rehabilitation and esthetic outcome. As an attempt to minimize the shrinkage of the alveolar bone, socket preservation was introduced to intervene with the natural process by providing a scaffold wi...

Objectives: To evaluate the self-perceived preparedness of final year undergraduate dental students in Malaysia and to compare the difference of preparedness level of final undergraduate student in public and private universities. Material and Methods: A cross-sectional questionnaire study was conducted using a validated questionnaire, Dental Under...

Periodontitis is a chronic inflammation of tooth supporting tissues (periodontal ligament, alveolar bone and gingiva). Due to the chronic and intensive inflammation, these tissues undergo accelerated cellular senescence (premature cells cycle arrest). This accelerated cellular senescence ends up with their degeneration and dramatic changes in the n...

Excessive exposure to fluoride during formation of teeth may lead to a severe hypomineralization condition, called dental fluorosis. Genes such as Collagen type 1 alpha 2 (COL1A2), Estrogen receptor (ESR), Prolactin (PRL), Catechol-o-methyltransferase (COMT), matrix metalloproteinase 20 (MMP20) and many others have been implicated in the incidence...

During orthodontic treatment, application of forces to move the teeth within the dento-alveolar complex is associated with structural and biological tissues changes. One of the main changes is hypoxia which is due to the compression of blood vessels resulting in insufficient oxygenation of the tissues. On orthodontic loading, hypoxia causes irrever...

Objectives The aim of this study was to investigate the impact of periodontal disease on the domains of oral health‐related quality of life of United Kingdom adults. Methods National representative data from the 2009 Adult Dental Health Survey, United Kingdom, was used in this study. Periodontal disease severity was measured using periodontal pock...

Orthodontic treatment requires moving and aligning the teeth into a favorable position aesthetically and functionally. To achieve that, the teeth are subjected to forces to push them to their new position. Loading of force on the crown causes tipping of tooth, subsequently the periodontal ligament is compressed adjacent to the alveolar bone on the...

All over the world, periodontal diseases are still prevalent and negatively affect the quality of life of young and adult population. Chronic periodontitis is an inflammatory polymicrobial disease characterized by episodic progressive destruction of gingivae, periodontal ligament, and bone. The inflamed cells of the periodontal structure undergo se...

Abstract— Objective: The aim of the study is to evaluate the efficacy of flaxseed paste on the surface lightness (L), chroma (C) and hue (h) of extracted teeth. Materials and Methods: Thirty extracted human teeth (incisors and canines) were selected and grouped into control (no treatment), flaxseed (treatment) and fluoride (positive control) groups...

This study was designed to investigate the effect of 3D TECA hydrogel on the inflammatory-induced senescence marker, and to assess the influence of the gel on the periodontal ligament fibroblasts (PDLFs) migration in wound healing in vitro. PDLFs were cultured with 20 ng/ml TNF-α to induce inflammation in the presence and absence of 50 μM 3D TECA g...

Objective: The main objective of this study was to determine the impact of discussion within family about the harmful effects of smoking on intention to initiate smoking in the long term among nonsmoking adolescents. Methods: Data from Global Youth Tobacco Survey for 25 European countries were used. The outcomes of interest were, therefore, the in...

Background:Periodontitis is an inflammatory disease resulting in the destruction and loss of tooth-supporting structures (periodontal ligament and alveolar bone) and if left untreated, it can lead to the loss of teeth. Objective: To develop an injectable composition of silanized hydroxypropyl methyl cellulose/titrated extract of Centella aisatica...

Background: Periodontitis is an inflammatory disease resulting in the destruction and loss of tooth-supporting structures (periodontal ligament fibers and alveolar bone). Objectives: This study describes the formulation, characterisation and evaluation of degradable bio-adhesive hydrogel for healing and regeneration of the periodontal structure. Me...

The present study was performed to evaluate the anti-ulcerogenic activity of ethanol extract of Centella asiatica against ethanol-induced gastric mucosal injury in rats. Five groups of adult Sprague Dawley rats were orally pre-treated respectively with carboxymethyl cellulose (CMC) solution (ulcer control group), Omeprazole 20 mg/kg (reference grou...

Background: Application of PCR techniques requiring only minute amounts of Genomic DNA. Thus, a less invasive, simpler to perform, and cheaper method to obtain DNA from exfoliated cells is desirable. We aim to develop a method that can obtain high quality of genomic DNA from one sample that allows for numerous application of PCR analysis. Objective...

The purpose of this study was to compare bone healing and coronal bone remodeling following both immediate and delayed placement of titanium dental implants in extraction sockets. The study included 49 patients (28 women, 21 men) in need of implant treatment in the anterior teeth region of either the maxilla or mandible. Twenty-three subjects recei...

Aim: To determine the mutation type of the p53 tumor suppressor gene (TSG) for exfoliated cells in salivary samples for pre oral squamous cell carcinoma and oral squamous cell carcinoma using DNA sequencing analysis. Methods: In this study, five salivary samples were collected from each group of the normal subjects, pre-oral squamous cell carcino...