Louise Hall

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Verified

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• BSc MSc PhD
• Senior Research Fellow at University of Leeds

Background Adherence to adjuvant endocrine therapy (AET) in women with breast cancer is poor. Multicomponent intervention packages are needed to address adherence barriers. Optimizing these packages prior to definitive evaluation can increase their effectiveness, affordability, scalability, and efficiency. Purpose To pilot procedures for an optimi...

Adherence to adjuvant endocrine therapy in women with breast cancer is low. We conducted a 24-1 fractional factorial pilot optimization trial to test four intervention components supporting medication adherence [text messages, information leaflet, acceptance and commitment therapy (ACT), self-management website], in the preparation phase of the mul...

Background Rates of burnout are currently at record high levels, and GPs experience higher burnout than many other specialties. Organisational interventions may reduce burnout, but few studies have investigated these in primary care. Aim The current study investigated whether breaks, both with and without social interactions, were associated with...

Adjuvant endocrine therapy (AET) reduces mortality in early-stage breast cancer, but adherence is low. We developed a multicomponent intervention to support AET adherence comprising: text messages, information leaflet, acceptance and commitment therapy (ACT), and side-effect website. Guided by the multiphase optimization strategy, the intervention...

Objective Non‐adherence to adjuvant endocrine therapy (AET) in women with breast cancer is common and associated with medication side‐effects and distress. We co‐designed an A cceptance and C ommitment T herapy intervent ion (ACTION) to enhance medication decision‐making and quality of life (QoL). We undertook a pilot trial of ACTION to inform the...

Objectives Aspirin could be offered for colorectal cancer prevention for the UK general population. To ensure the views of the general population are considered in future guidance, we explored public perceptions of aspirin for preventive therapy. Design We conducted an online survey to investigate aspirin use, and awareness of aspirin for cancer p...

Background: Adjuvant endocrine therapy (AET) reduces mortality risk in early-stage breast cancer, but adherence is low. We developed a multicomponent intervention to support AET adherence comprising: text messages; information leaflet; acceptance and commitment therapy (ACT); side-effect management website. Guided by the multiphase optimization str...

Objectives: Aspirin could be offered for colorectal cancer prevention for the UK general population, following the Australian national guidance for adults aged 50-70. To ensure the views of the general population are considered in future guidance, we explored public perceptions of aspirin for preventive therapy.Design: We conducted an online survey...

Background: Adherence to adjuvant endocrine therapy (AET) is low in women with breast cancer. Negative beliefs about the necessity of AET and high concerns are barriers to adherence. Purpose: To use the multiphase optimization strategy to optimize the content of an information leaflet intervention, to change AET beliefs. Methods: We conducted...

The increasing prevalence of mental health issues is a global concern, and implementing low-cost, effective, population-level interventions is critical. Physical activity interventions, including climbing, hold promise as one way to bridge this gap. Climbing is a non-mainstream form of physical activity that is gaining popularity and is being incre...

Background: The Refining and Optimising a behavioural intervention to Support Endocrine Therapy Adherence (ROSETA) programme has developed four intervention components aiming to improve medication adherence in women with early-stage breast cancer. These are (a) text messages, (b) information leaflet, (c) Acceptance and Commitment Therapy-based guid...

Background: The Refining and Optimising a behavioural intervention to Support Endocrine Therapy Adherence (ROSETA) programme has developed four intervention components aiming to improve medication adherence in women with early-stage breast cancer. These are (a) text messages, (b) information leaflet, (c) Acceptance and Commitment Therapy-based guid...

Introduction Women with breast cancer who do not adhere to adjuvant endocrine therapy (AET) have increased risks of mortality and recurrence. There are multiple barriers to AET adherence, including medication side-effects, beliefs about medication, memory and psychological distress. We developed four intervention components, each targeting a differ...

Background The National Institute for Health and Care Excellence (NICE) 2020 guidelines recommends aspirin for colorectal cancer prevention for people with Lynch syndrome. Strategies to change practice should be informed by understanding the factors influencing prescribing. Aim To investigate the optimal type and level of information to communicat...

Background Adjuvant endocrine therapy (AET) reduces the risk of breast cancer recurrence and mortality. However, up to three-quarters of women with breast cancer do not take AET as prescribed. Existing interventions to support adherence to AET have largely been unsuccessful, and have not focused on the most salient barriers to adherence. This paper...

Background The National Institute for Health and Care Excellence (NG151) recommends considering daily aspirin for people with Lynch syndrome to reduce colorectal cancer risk. However, deciding whether to initiate aspirin could be a complex decision for patients and their healthcare providers, as both the potential benefits and harms need to be cons...

BACKGROUND Adjuvant endocrine therapy (AET) reduces breast cancer recurrence and mortality in women with early-stage breast cancer. Unintentional nonadherence to AET is common (e.g., forgetting to take medication). Forming habits surrounding medication-taking could reduce reliance on memory and improve AET adherence. Short Message Service (SMS) tex...

Background: Adjuvant endocrine therapy (AET) reduces breast cancer recurrence and mortality in women with early-stage breast cancer. Unintentional nonadherence to AET is common (eg, forgetting to take medication). Forming habits surrounding medication taking could reduce reliance on memory and improve AET adherence. SMS text messaging intervention...

Background Adherence to adjuvant endocrine therapy is affected by medication side-effects and associated distress. Previous interventions focused on educating women to enhance adherence have proved minimally effective. We co-designed an Acceptance and Commitment Therapy (ACT) intervention to enhance medication decision-making and quality of life by...

Background: The National Institute for Health and Care Excellence (NG151) recommends considering daily aspirin for people with Lynch syndrome to reduce colorectal cancer risk. However, patients and their healthcare providers considering preventive therapy need to negotiate complex decisions that weigh up potential benefits and harms.Method: We cond...

Background: Returning a trial questionnaire is a behaviour affected by a range of psychological and contextual factors. Previously tested Short Message Service (SMS) messages to prompt questionnaire return have not addressed these factors, and have not been characterised by established taxonomies of behaviour change techniques (BCTs). Purpose: We a...

Background Adjuvant endocrine therapy (AET) reduces the risk of breast cancer recurrence and mortality. However, up to three-quarters of women with breast cancer do not take AET as prescribed. Existing interventions to support adherence to AET have largely been unsuccessful, and have not focused on the most salient barriers to adherence. This paper...

We undertook a systematic review to synthesise the data on attitudes and behaviour towards the use of aspirin for cancer prevention, and healthcare providers' attitudes towards implementing aspirin in practice. Searches were carried out across 12 databases (e.g. MEDLINE, EMBASE). We used the Mixed Methods Appraisal Tool to evaluate study quality, a...

Purpose Side-effects of adjuvant endocrine therapy (AET) are common in breast cancer survivors, and can affect adherence to treatment. We synthesised the evidence for strategies to self-manage these side-effects. Methods We searched for systematic reviews and clinical guidelines on self-management strategies for AET side-effects (arthralgia, fatig...

Background: Brief interventions (BI) involving physical activity (PA) screening and/or advice are recommended in primary care. However, the frequency of delivery is unknown. Aim: To examine the extent to which PA BI are delivered in primary care and explore factors associated with delivery, receipt, and patient receptivity. Design: A mixed methods...

Background Physical activity (PA) brief interventions (BIs) involving screening and/or advice are recommended in primary care but frequency of delivery is unknown. Aim To examine the extent to which PA BIs are delivered in primary care, and explore factors associated with delivery, receipt, and patient receptivity. Design and setting A mixed-meth...

Purpose Women’s worry about developing breast cancer may influence their decision to use preventive therapy. However, the direction of this relationship has been questioned. We prospectively investigated the relationship between breast cancer worry and uptake of preventive therapy. The socio-demographic and clinical factors associated with high bre...

Objectives The aim of this work was to co-develop an Acceptance and Commitment Therapy (ACT) intervention to support medication adherence and quality of life in breast cancer survivors (BCSs). The research approach was intervention co-development. Methods The sample consisted of BCS focus groups (n = 24), health care provider (HCP) interviews (n =...

Background Adherence to adjuvant endocrine therapy is affected by medication side-effects and associated distress. Previous interventions focused on educating women to enhance adherence have proved minimally effective. We co-designed an Acceptance and Commitment Therapy (ACT) intervention to enhance medication decision-making and quality of life by...

Background: Clinical guidelines worldwide are increasingly recommending aspirin for cancer prevention. We undertook a systematic review to synthesise the quantitative and qualitative data on attitudes and behaviour towards the use of aspirin for cancer prevention, and healthcare providers’ attitudes and behaviour towards implementing aspirin in cli...

Purpose: Women’s worry about developing breast cancer may influence their decision to use preventive therapy. However, the direction of this relationship has been questioned. We prospectively investigated the relationship between breast cancer worry and uptake of preventive therapy. The socio-demographic and clinical factors associated with high br...

Colorectal cancer (CRC) represents a global public health concern. CRC screening is associated with significant reductions in CRC incidence and mortality, however, uptake is suboptimal. This systematic review and meta-analysis of randomised controlled trials explored the effectiveness of interventions designed to increase screening uptake, plus the...

Tamoxifen reduces breast cancer incidence in women at increased risk, but may cause side-effects. We examined women's knowledge of tamoxifen's potential harms and benefits, and the extent to which knowledge reflects subjective judgements of awareness and decision quality. After a hospital appointment, 408 (55.7%) women at increased risk of breast c...

It is well established that high levels of work-related stress are impacting negatively on health, wellbeing and work-related outcomes in healthcare professionals. There is also growing evidence to show that job strain, burnout and low wellbeing are associated with poor patient safety and medical errors. In the UK, errors are estimated to cost the...

Background: Tamoxifen reduces breast cancer incidence in women at increased risk, but may cause side-effects. We examined women’s knowledge of tamoxifen’s potential harms and benefits, and the extent to which knowledge reflects subjective judgements of awareness and decision quality. Methods: After a hospital appointment, 408 (55.7%) women at incre...

Background: General practitioners (GPs) have particularly high levels of burnout and poor wellbeing. Whilst burnout and poor wellbeing are associated with poorer safety outcomes within secondary care, there have been no quantitative studies investigating this within primary care. Furthermore, little is known about how occupational demands, burnout...

Background: Sonographers report high levels of burnout. For those working in obstetric ultrasound, one frequently cited stressor is the delivery of bad or difficult news. Training in news delivery may reduce sonographer stress levels, but no studies have investigated sonographer experiences of this training. Aims: To investigate sonographer experi...

Several interventions have targeted dyads to promote physical activity (PA) or reduce sedentary behaviour (SB), but the evidence has not been synthesised. Sixty-nine studies were identified from MEDLINE, PsycINFO, and Web of Science, and 59 were included in the main meta-analyses (providing 72 independent tests). Intervention details, type of dyadi...

Rising levels of burnout and poor well-being in healthcare staff are an international concern for health systems. The need to improve well-being and reduce burnout has long been acknowledged, but few interventions target mental healthcare staff, and minimal improvements have been seen in services. This review aimed to examine the problem of burnout...

Background Primary care physicians are particularly prone to high levels of burnout and poor wellbeing. Despite this, no qualitative studies have specifically investigated the best ways to improve wellbeing and prevent burnout in primary care physicians. Previous interventions within primary care have been person-oriented and mainly focused on mind...

Objectives: The aims of the study were (1) to explore whether primary care physicians (general practitioners [GPs]) perceive burnout and well-being to impact on the quality and safety of patient care and (2) to determine potential mechanisms behind these associations. Method: Five focus groups with 25 practicing GPs were conducted in England, ei...

Abstract Background There is growing interest in the relationships between depressive symptoms and burnout in healthcare staff and the safety of patient care. Depressive symptoms are higher in healthcare staff than the general population and overlap conceptually with burnout. However, minimal research has investigated these variables in nurses. Gi...

Objective: To determine whether there is an association between healthcare professionals' wellbeing and burnout, with patient safety. Design: Systematic research review. Data sources: PsychInfo (1806 to July 2015), Medline (1946 to July 2015), Embase (1947 to July 2015) and Scopus (1823 to July 2015) were searched, along with reference lists o...