Louis de Lescure

Louis de Lescure
Colorado State University | CSU · Department of Chemistry

Bachelor of Science

About

3
Publications
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Publications

Publications (3)
Preprint
Pyridine halogenation reactions are crucial for obtaining the vast array of derivatives required for drug and agrochemical development. Yet, despite more than a century of synthetic endeavors, there are no broadly applicable 3-selective halogenation processes that function directly from pyridine C–H precursors. We have developed a ring-opening, hal...
Article
Full-text available
The ability to manipulate C-C bonds for selective chemical transformations is challenging and represents a growing area of research. Here, we report a formal insertion of diazo compounds into the "unactivated" C-C bond of benzyl bromide derivatives catalyzed by a simple Lewis acid. The homologation reaction proceeds via the intermediacy of a phenon...
Article
Full-text available
2‐Formylphenylboronic acid condenses with active methylene reagents like α‐amino esters, ketones, and lactams directly to give benzo‐fused 1‐hydroxy‐2,1‐azaborines in good yields within minutes under microwave‐accelerated conditions. The new stable boron heterocycles prepared to demonstrate this approach were characterized by NMR spectroscopy. Thre...

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