Lorenzo Cobianchi

University of Pavia, Italy. Policlinico San Matteo Pavia Fondazione IRCCS · Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy

Background Investigating the context of trauma and acute care surgery, the article aims at understanding the factors that can enhance some ethical aspects, namely the importance of patient consent, the perceptiveness of the ethical role of the trauma leader, and the perceived importance of ethics as an educational subject. Methods The article empl...

Background: Investigating the context of trauma and acute care surgery, the article aims at understanding the factors that can enhance some ethical aspects, namely the importance of patient consent, the perceptiveness of the ethical role of the trauma leader, and the perceived importance of ethics as an educational subject. Methods: The article emp...

INTRODUZIONE: Negli ultimi anni, ed ancor più, a seguito delle necessità di distanziamento sociale generatesi a causa della pandemia mondiale COVID-19, l'e-health si è trasformata in una realtà sempre più concreta e diffusa nella pratica clinica anche per il personale infermie-ristico, che lavora in prima linea a contatto diretto con i pazienti. A...

Negli Stati Uniti, dal 1999 al 2019, l’overdose da oppioidi, derivante sia da farmaci regolarmente prescritti che acquisiti o assunti illecitamente, è stata la causa di morte di quasi 500.000 persone. I decessi sono via via aumentati nel tempo. Questo andamento è stato accompagnato anche da seri rischi ed effetti collaterali, portando ormai così gl...

The purpose of the research topic call “New Frontiers for Artificial Intelligence in Surgical Decision Making and its Organizational Impacts “ was to collect the recent developments and undergoing studies in AI in surgery and surgical oncology. More in detail, the aim was to gather contributions on the advancement, deployment, use, and implementati...

Aim: To evaluate the association between pretreatment diffusion-weighted MRI (DW-MRI) and 12-month radiological response in locally recurrent rectal cancer treated with carbon ion radiotherapy. Methods: Histogram analysis was performed on pretreatment DW-MRI for patients re-irradiated with carbon ion radiotherapy for local recurrence of rectal canc...

Background Pancreatic cancer represents one of the leading causes of cancer-related death worldwide. Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC), normothermic intraperitoneal chemotherapy (NIPEC), and pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been proven with curative intent mainly...

La chirurgia d'urgenza e del trauma è un contesto particolarmente complesso, in cui il personale sanitario deve lavorare sotto pressione, spesso con limitata conoscenza ri-spetto alla causa del trauma, all'identità del paziente, alle sue patologie pregresse e preferenze di cura. I team di chirurgia d'urgenza sono multidisciplinari e coordinati da u...

Background: Artificial intelligence (AI) applications aiming to support surgical decision-making processes are generating novel threats to ethical surgical care. To understand and address these threats, we summarize the main ethical issues that may arise from applying AI to surgery, starting from the Ethics Guidelines for Trustworthy Artificial In...

Frontiers in Oncology & Frontiers in Surgery joint call for papers ******************************************************************************* Link: https://www.frontiersin.org/research-topics/37943/new-frontiers-in-pancreatic-cancer-care-multidisciplinary-approaches-the-role-of-pancreas-units-and *******************************************...

At present, telemedicine and remote visits represent one alternative to in-person visits to meet patients’ ambulatory care needs during the COVID-19 pandemic and its enforced social distancing requirements. Telemedicine is becoming popular in several clinical disciplines, including pain medicine and oncology. Two out of three chronic pain patients...

Disasters like the recent COVID-19 pandemic can benefit from the use of digital tools and Knowledge Management Systems (KMSs) to manage the emergency and improve the resilience of the system. Such KMSs must prove the quality of the system, service, situation, and knowledge which is gathered, transferred, and shared. However, KMSs must cope with the...

Re-irradiation of pelvic recurrent gynecological cancer is a challenge due to the proximity of high-radiation-sensitive organs, such as the bowel and the urinary tract. Hadrontherapy for re-irradiation emerges as a safe and effective treatment with a mild rate of morbidity of surrounding normal tissue. To improve the dose to the tumor, a prophylact...

The assurance of patient safety in emergency general surgery remains challenging due to the patients' high-risk underlying conditions and the wide variability in emergency surgical care provided around the globe. The authors of this article convened as an expert panel on patient safety in surgery at the 8 th International Conference of the World So...

Acute left colonic diverticulitis (ALCD) in the elderly presents with unique epidemiological features when compared with younger patients. The clinical presentation is more nuanced in the elderly population, having higher in-hospital and postoperative mortality. Furthermore, geriatric comorbidities are a risk factor for complicated diverticulitis....

Acquired congenital esophageal malformations, such as malignant esophageal cancer, require esophagectomy resulting in full thickness resection, which cannot be left untreated. The proposed approach is a polymeric full-thickness scaffold engineered with mesenchymal stem cells (MSCs) to promote and speed up the regeneration process, ensuring adequate...

Background: Investigating the context of trauma and acute care surgery, the article aims at understanding the factors that can enhance some ethical aspects, namely the importance of patient consent, the perceptiveness of the ethical role of the trauma leader, and the perceived importance of ethics as an educational subject. Methods: The article emp...

Rokitansky-Aschoff sinuses (RAS) are a common imaging finding in gallbladder adenomyomatosis (ADM), often presenting as fundal cystic spaces. Intracholecystic papillary neoplasm (ICPN) is a relatively uncommon pre-invasive tumor of the gallbladder epithelium that rarely involves RAS mucosa. We compare two cases that showed similar fundal cystic spa...

Introduction: The paper investigates the critical care staff's support towards organ donation by analysing how their attitude, knowledge, confidence, engagement, and training can act as predictors of donation consent rates. Our study focused on hospitals in the Apulia Region, Italy. Material and methods: The study employs a quantitative methodol...

Pancreatic Cancer represents one of the most severe diseases, with high mortality rates. The scientific community is actively working on new strategies and integrated protocols that combine chemotherapy, radiation therapy, and surgery. Carbon ion radiotherapy (CIRT) looks like a promising technique to allow surgical resection. Still, few centres wo...

On January 2020, the WHO Director General declared that the outbreak constitutes a Public Health Emergency of International Concern. The world has faced a worldwide spread crisis and is still dealing with it. The present paper represents a white paper concerning the tough lessons we have learned from the COVID-19 pandemic. Thus, an international an...

Background A favourable attitude towards organ donation and transplantation is fundamental among health professionals to promote consent, especially in a young healthcare system like Albania. Objective To analyse the differences in the attitude towards organ donation and transplantation and the influencing factors among medical doctors- and nurses...

Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma's causes or the patient's personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ens...

Artificial Intelligence (AI) is gaining traction in several industrial and service sectors, including healthcare. From a bibliometric perspective, the number of AI-related biomedical studies is rising, with more than 21,000 articles in 2020 alone. Several algorithms were approved for clinical use worldwide, with radiology and cardiology standing as...

Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma's causes or the patient's personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ens...

Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma's causes or the patient's personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ens...

Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma's causes or the patient's personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ens...

Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma's causes or the patient's personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ens...

Background Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma’s causes or the patient’s personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ensu...

Surgical Trauma Teams are characterised by the need to face unexpected situations, with little time to make decisions. In emergency contexts, teams must act in a coordinated way, ensuring, at the same time, proper knowledge transfer and sharing to reach the best possible outcome for the patient. Considering the specific research context, team dynam...

Starting from a recent experience with breast cancer patients, our paper argues how co-production may represent a successful strategy to empower patients and reach better surgical outcomes, especially when a multistakeholder approach is employed. Co-production, where clinicians and other meaningful stakeholders like citizens, patient's associations...

Background Organ transplant is considered a life-saving treatment for patients with end-stage diseases. The knowledge of the population and their opinions can influence the willingness of family members and patients to consent to organ and tissue donation. This work aims to evaluate the effectiveness of a webinar intervention as a knowledge transla...

As organizações são desafiadas pela necessidade de transformar o Conhecimento Dinâmico, incorporado em cada trabalhador, em Conhecimento Estático, enraizado em informação documental factual. No entanto, a inovação e a criação de conhecimento parecem ser facilitadas pelo conhecimento pessoal e experiências de vida das pessoas, que parecem ser dinâmi...

Organizations are challenged by the need to transform Dynamic Knowledge, embedded in each worker, into Static Knowledge, rooted in factual documental information. However, innovation and knowledge creation seem to be facilitated by the personal knowledge and life experiences of people, which appear to be dynamic. The tensions between Dynamic and St...

The main goal of this article is to understand the potential learning applications based on AI technologies for health higher education students. We employed a Systematic Literature Review, contributing to explore to what extent AI technologies are currently influencing the Health learning processes in higher education and the skills developed duri...

The COVID-19 pandemic changed expectations for information dissemination and use around the globe, challenging accepted models of communications, leadership, and social systems. We explore how social media discourse about COVID-19 in Italy was affected by the rapid spread of the virus, and how themes in postings changed with the adoption of social...

Introduction: The Coronavirus pandemic (Covid-19) was first identified in December 2019 in the city of Wuhan, China, and later caused a severe health crisis, causing massive disruptions to most healthcare systems worldwide. The Covid-19 health emergency has seen healthcare workers in the front line facing all the difficulties related to the care b...

Italy adopted a law on chronic pain in March 2010, which focused on detection and management of this symptom, that affects approximately 25% of the population. The aim of this study is to analyze the interest of the Italian population in palliative care and chronic pain and to understand whether the Law 38/2010 made an impact on the internet search...

The purpose of the present call is to collect the recent developments and undergoing studies in bioengineering, tissue and organ regeneration taking into account: biological and synthetic scaffolds; animal and human tissue decellularization; scaffold recellularization; 3D bioprinting; organoid technology. The other goal is to define future possibl...

The Human-Centred Management (HCM) model focuses on the importance of the wellbeing of people as workers and users. The healthcare sector stands as one of the key fields responsible for the continuous improvement of the physical and mental wellbeing across society. This study was conducted in Italy at a time when the healthcare sector was undergoin...

Knowledge Translation (KT) is a set of methods and approaches to transfer new knowledge to the practice of medicine, involving researchers, clinicians, managers, patients, and policymakers. KT appears as a key topic in today’s healthcare system, which is under unprecedented pressure. The COVID-19 pandemic of 2020 has further underlined the relevanc...

The chapter investigates the role of Soft Skills necessary to create practical tools to support the knowledge translation process, analyzing case studies from highly skilled healthcare organizations. Knowledge Translation (KT) is defined as the capability to make knowledge sharable and accessible to various stakeholders in different contexts. Effec...

Telemedicine and remote visits are becoming more and more popular in several medical disciplines, including oncology. The Covid-19 pandemic has enhanced the need to continue to meet patients' ambulatory care necessities ensuring social distancing and limiting the access to clinical facilities. The National Cancer Institute of Aviano, Italy, has rec...

Healthcare is one of the most relevant fields in today's world, given its fundamental role in impacting on people's health and well-being. Nowadays, knowledge management in healthcare is particularly crucial, given the significant changes and challenges which are affecting the sector, including the recent Covid-19 pandemic, which required a fast r...

Italy was one of the countries most affected by the number of people infected and dead during the first COVID-19 wave. The authors describe the rapid rollout of a population health clinical and organizational response in preparedness and capabilities to support the first wave of the COVID-19 pandemic in the Italian province of Modena. The authors r...

Abstract. Introduction. The covid-19 pandemic, a public health emergency of international relevance, has forced health authorities to perform quick decision-making, and to reallocate resources appropriately. Non-pharmaceutical interventions, such as measures for the containment of the spread of the infection , have been accompanied by a massive reo...

The call aims to explore the potential applications of novel digital technologies (such as IoT, big-data analytics, AI, robotics, the blockchain, additive manufacturing, and cybersecurity) and knowledge management systems to enhance the traditional public-health strategies and knowledge management strategies in uncertain times, for supporting the d...

Pancreatic ductal adenocarcinoma (PDAC) is one of the major causes of death in the Western world, and it is estimated to become the second leading cause of tumour-related mortality in the next 10 years. Among pancreatic cancers, ductal adenocarcinomas are by far the most common, characterised by a challenging diagnosis due to the lack of initial an...

Knowledge translation is the ability to translate concepts and ideas effectively among different stakeholders, leading to innovation and new knowledge. Translating knowledge is particularly challenging in the healthcare sector, which has been experiencing a shift from a centralized and sequential model of value creation to a more distributed and op...

Mini Abstract: Diverse teams have proven their ability to reach superior performance and improve patients' outcomes. Nevertheless, differences in race, gender, age, nationality, skills, education, and experience act as powerful barriers to diversity and inclusion, which negatively impacts multiple healthcare organizations and limits the potential o...

In this special issue, we would like to explore the potential applications of novel digital technologies (such as IoT, big-data analytics, AI, robotics, the blockchain, additive manufacturing, and cybersecurity) to enhance the traditional public-health strategies for supporting the development of an anti-fragile healthcare sector, for innovating th...

Knowledge translation can be understood as the ability to translate concepts between different contexts by stakeholders who have different skills, aims, and even feelings in their relation to such concepts. Knowledge translation tools allow for the effective transfer of existing knowledge as well as the emergence of new knowledge of value to some o...

Knowledge translation (KT) is the ability to make knowledge accessible to different stakeholders by translating it into various contexts. Translating knowledge is particularly crucial in the healthcare sector, which is currently under significant pressure due to technological innovation, increasing demand of services by an ageing population, budget...

The literature states that physical activity can contribute to faster rehabilitation of cancer patients. Educating patients to correct daily fitness activity results in better life quality. However, the need for a tailored approach and the absence of recommendations valid for all make it difficult to implement any program successfully. The Oncology...

Introduction: The sudden increase in the number of critically ill patients following a disaster can be overwhelming. Study objective: The main objective of this study was to assess the real number of available and readily freeable beds ("bed surge capacity") and the availability of emergency operating rooms (OR) in a maximum emergency using a th...

The recent literature has highlighted the need for surgical systems to develop antifragile strategies in recovering from the COVID-19 crisis. Building on crisis management theory, our paper explores antifragility principles and their possible practical applicability to the surgical system.

Organizations are challenged by the need to transform Dynamic Knowledge, embedded in each worker, into Static Knowledge, rooted in factual documental information. However, innovation and knowledge creation seem to be facilitated by the personal knowledge and life experiences of people, which appear to be dynamic. The tensions between Dynamic and St...

New technologies can foster the development of new sustainable business models (SBMs). Our paper wants to investigate how the blockchain can facilitate the development of new SBMs by analyzing some real-world case studies. Findings highlight how the characteristics of the blockchain can extend existing theories in leading to new SBMs.

The current unprecedented coronavirus 2019 (COVID-19) crisis has accelerated and enhanced e-learning solutions. During the so-called transition phase, efforts were made to reorganize surgical services, reschedule elective surgical procedures, surgical research, academic education, and careers to optimize results. The intention to switch to e-learni...

Surgical mortality is the most significant measure of outcome in surgical healthcare. The objective was to assess surgical 30 days mortality and improve the identification of predictors for personalized risk stratification of patients undergoing elective and emergency surgery. The study was conducted as a single-center cohort retrospective observat...