Lorenza Dall'Aglio

Lorenza Dall'Aglio
Erasmus MC | Erasmus MC · Department of Child and Adolescent Psychiatry

PhD fellow in Population Neuroimaging and Developmental Psychopathology

About

7
Publications
1,423
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77
Citations
Introduction
PhD fellow conducting empirical research on the neurobiology of anxiety and depression in childhood and adolescence. Open science advocate.
Additional affiliations
November 2017 - September 2019
Erasmus MC
Position
  • Research trainee
Description
  • Conducted empirical research on DNA methylation and the caregiving environment. Performed latent variable modelling and epigenetic analyses (DMP, DMR, candidate gene follow-up) through R (packages: lavaan, cgpassoc, dmrff).
November 2016 - November 2017
Erasmus MC
Position
  • Research Intern
Description
  • Conducted a systematic review on the role of DNA methylation and histone modifications in ASD and ADHD.
Education
October 2019 - October 2023
Erasmus MC
Field of study
  • Neuroimaging
September 2018 - September 2019
King's College London
Field of study
  • Behavioural Genetics
August 2015 - August 2018
Erasmus University Rotterdam
Field of study
  • Psychology

Publications

Publications (7)
Preprint
Full-text available
Background: Associations between attention-deficit/hyperactivity disorder (ADHD) and brain morphology have been reported, although with several inconsistencies. These may partly stem from confounding bias, which could distort associations and limit generalizability. We examined how associations between brain morphology and ADHD symptoms change with...
Article
Full-text available
Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. However, despite this widespread endorsement and support, as well as various efforts led by early career researchers, open research is yet to be...
Article
Full-text available
Background. Experimental work in animals has shown that DNA methylation (DNAm), an epigenetic mechanism regulating gene expression, is influenced by typical variation in maternal care. While emerging research in humans supports a similar association, studies to date have been limited to candidate gene and cross-sectional approaches, with a focus on...
Preprint
Full-text available
Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. However, despite this widespread endorsement and support, open research is yet to be widely adopted, with early career researchers being the not...
Article
Full-text available
Abstract Background Major Depression (MD) is determined by a multitude of factors including genetic risk variants that regulate gene expression. Here, we examined the genetic component of gene expression in MD by performing a Transcriptome-Wide Association Study (TWAS), inferring gene expression-trait relationships from genetic, transcriptomic, and...
Preprint
Full-text available
Background Major Depression (MD) is determined by a multitude of factors including genetic risk variants which regulate gene expression (GE). Here, we examined the genetic component of GE in MD by performing a Transcriptome-Wide Association Study (TWAS), inferring GE-trait relationships from genetic, transcriptomic and phenotypic information. Meth...
Article
Full-text available
Epigenetic processes have been suggested as key mechanisms in the etiology of neurodevelopmental disorders. This systematic review summarizes the current evidence for an association between epigenetics and Autism Spectrum Disorder (ASD) and Attention/Deficit-Hyperactivity Disorder (ADHD). Six databases were searched until the 24 th of October 2017....

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