Lorenza Dall'AglioErasmus MC | Erasmus MC · Department of Child and Adolescent Psychiatry
Lorenza Dall'Aglio
PhD fellow in Population Neuroimaging and Developmental Psychopathology
About
7
Publications
1,423
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77
Citations
Introduction
PhD fellow conducting empirical research on the neurobiology of anxiety and depression in childhood and adolescence. Open science advocate.
Skills and Expertise
Additional affiliations
November 2017 - September 2019
Position
- Research trainee
Description
- Conducted empirical research on DNA methylation and the caregiving environment. Performed latent variable modelling and epigenetic analyses (DMP, DMR, candidate gene follow-up) through R (packages: lavaan, cgpassoc, dmrff).
November 2016 - November 2017
Position
- Research Intern
Description
- Conducted a systematic review on the role of DNA methylation and histone modifications in ASD and ADHD.
Education
October 2019 - October 2023
September 2018 - September 2019
August 2015 - August 2018
Publications
Publications (7)
Background: Associations between attention-deficit/hyperactivity disorder (ADHD) and brain morphology have been reported, although with several inconsistencies. These may partly stem from confounding bias, which could distort associations and limit generalizability. We examined how associations between brain morphology and ADHD symptoms change with...
Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. However, despite this widespread endorsement and support, as well as various efforts led by early career researchers, open research is yet to be...
Background. Experimental work in animals has shown that DNA methylation (DNAm), an
epigenetic mechanism regulating gene expression, is influenced by typical variation in maternal care. While emerging research in humans supports a similar association, studies to date have been limited to candidate gene and cross-sectional approaches, with a focus on...
Increasingly, policies are being introduced to reward and recognise open research practices, while the adoption of such practices into research routines is being facilitated by many grassroots initiatives. However, despite this widespread endorsement and support, open research is yet to be widely adopted, with early career researchers being the not...
Abstract
Background
Major Depression (MD) is determined by a multitude of factors including genetic risk variants that regulate gene expression. Here, we examined the genetic component of gene expression in MD by performing a Transcriptome-Wide Association Study (TWAS), inferring gene expression-trait relationships from genetic, transcriptomic, and...
Background
Major Depression (MD) is determined by a multitude of factors including genetic risk variants which regulate gene expression (GE). Here, we examined the genetic component of GE in MD by performing a Transcriptome-Wide Association Study (TWAS), inferring GE-trait relationships from genetic, transcriptomic and phenotypic information.
Meth...
Epigenetic processes have been suggested as key mechanisms in the etiology of neurodevelopmental disorders. This systematic review summarizes the current evidence for an association between epigenetics and Autism Spectrum Disorder (ASD) and Attention/Deficit-Hyperactivity Disorder (ADHD). Six databases were searched until the 24 th of October 2017....
