Lorena Rodríguez García

Lorena Rodríguez García
University Isabel I · Department of Physical Education

PhD

About

19
Publications
2,712
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297
Citations
Citations since 2017
2 Research Items
207 Citations
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Introduction
Lorena Rodríguez García currently works at the Department of Physical Education, University Isabel I. Lorena does research in Teacher Education, Cell Biology and Physiology. Their current project is 'Influencia del polimorfismo del receptor de andrógenos en la masa ósea, masa muscular y condición física en niños y niñas'.
Skills and Expertise

Publications

Publications (19)
Article
Background: To evaluate the effectiveness of a multicomponent supervised and unsupervised training program focused on muscle power to counteract the potential changes in sedentary behavior, disability, physical activity (PA), and health-related quality of life (HRQoL) caused by the COVID-19 pandemic domiciliary confinement in prefrail older adults...
Article
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Introduction: Androgens play a major role in fat oxidation; however, the effects of androgens depend, among other factors, on the intrinsic characteristics of the androgen receptor (AR). Lower repetitions of CAG and GGN polymorphism appear to have a protective effect on fat accumulation in the transition from adolescent to mid-twenties. Whether a...
Article
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To determine the influence of androgen receptor CAG and GGN repeat polymorphisms on fat mass and maximal fat oxidation (MFO), CAG and GGN repeat lengths were measured in 128 young boys, from which longitudinal data were obtained in 45 of them [mean ± SD: 12.8 ± 3.6 years old at recruitment, and 27.0 ± 4.8 years old at adult age]. Subjects were grou...
Article
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Background: Shorter CAG and GGN androgen receptor (AR) repeat polymorphisms are associated with stronger androgen signaling, and therefore, could influence lean mass and exercise performance during growth. Methods: Physical fitness and body composition were measured by standardized procedures and the length of CAG and GGN repeats was determined...
Article
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To determine the contribution of convective and diffusive limitations to (V) over dot(O2 peak) during exercise in humans, oxygen transport and haemodynamics were measured in 11 men (22 +/- 2years) during incremental (IE) and 30s all-out cycling sprints (Wingate test, WgT), in normoxia (Nx, P-IO2: 143mmHg) and hypoxia (Hyp, P-IO2: 73mmHg). Carboxyha...
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INTRODUCTION the human androgen receptor (AR) gene possesses two trinucleotide polymorphic repeats, (CAG and GGN) that affect the amount of AR protein translated. In this study, we genotyped these polymorphic tracts in a representative sample of Caucasian children (Tanner ≤ 5), 152 boys (11.5 } 2.6 yrs) and 116 girls (10.1 } 3.2 yrs) from Spain a...
Article
This study was designed to investigate the association of gender, fibre type composition, and anaerobic performance with the basal skeletal muscle signalling cascades regulating muscle phenotype. Muscle biopsies were obtained from 25 men and 10 women all young and healthy. Protein phosphorylation of Thr(172)AMPKα, Ser(221)ACCβ, Thr(286)CaMKII as we...
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The extremely high energy demand elicited by sprint exercise is satisfied by an increase in oxygen consumption combined with a high glycolytic rate, leading to a marked lactate accumulation, increased AMP/ATP ratio, reduced NAD(+)/NADH.H(+) and muscle pH, which are accompanied by marked Thr(172)-AMPKα phosphorylation during the recovery period. To...
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To determine if the muscle signalling response to a 30 s all-out sprint exercise is modulated by the exercise mode and the endocrine response, 27 healthy volunteers were divided in 2 groups that performed isokinetic (10 men and 5 women) and isoinertial (7 men and 5 women) Wingate tests. Blood samples and vastus lateralis muscle biopsies were taken...
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AMP-activated protein kinase (AMPK) is a major mediator of the exercise response and a molecular target to improve insulin sensitivity. To determine if the anaerobic component of the exercise response, which is exaggerated when sprint is performed in severe acute hypoxia, influences sprint exercise-elicited Thr(172)-AMPKα phosphorylation, 10 volunt...
Article
Androgen receptor (AR) CAG(n) (polyglutamine) and GGN(n) (polyglycine) repeat polymorphisms determine part of the androgenic effect and may influence adiposity. The association of fat mass, and its regional distribution, with the AR CAG(n) and GGN(n) polymorphisms was studied in 319 and 78 physically active nonsmoker men and women (mean ± SD: 28.3...
Article
Full-text available
To determine if there is a sex dimorphism in the skeletal muscle signaling response to sprint exercise, 17 men and ten women performed a 30-s Wingate test. Muscle biopsies were taken before, immediately after the exercise and at 30 and 120 min during the recovery period. Thr(172)-AMPKα, Ser(221)-ACCβ, Thy(705)-STAT3, Thr(202)/Thy(204)-ERK1/2 and Th...

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