Lore Wyers

Lore Wyers
University of Antwerp | UA · Department of rehabilitation sciences and physiotherapy

Master of Science in Rehabilitation Sciences and Physiotherapy

About

16
Publications
805
Reads
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47
Citations
Citations since 2016
16 Research Items
47 Citations
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Publications

Publications (16)
Article
Full-text available
Reaching for an object in space forms the basis for many activities of daily living and is important in rehabilitation after stroke and in other neurological and orthopedic conditions. It has been the object of motor control and neuroscience research for over a century, but studies often constrain movement to eliminate the effect of gravity or redu...
Article
Full-text available
Contributions from premotor and supplementary motor areas to reaching behavior in aging humans are not well understood. The objective of these experiments was to examine effects of perturbations to specific cortical areas on the control of unconstrained reaches against gravity by younger and older adults. Double-pulse transcranial magnetic stimulat...
Article
Background Dravet Syndrome (DS) is a developmental and epileptic encephalopathy, characterized by drug resistant infantile onset seizures and cognitive and motor impairment. Walking problems progressively occur and crouch gait is frequently observed. Muscle weakness is hypothesized as contributing impairment. Yet, so far, no studies have performed...
Article
Background Dravet Syndrome (DS) is a developmental and epileptic encephalopathy characterized by severe drug-resistant seizures and associated with cognitive and motor impairments. Walking problems are frequently observed. As the foot plays a key role during walking, compromised foot function can be a feature of deviant gait. Aim To investigate fo...
Preprint
Full-text available
Background The specific and dynamic contributions of premotor and supplementary motor areas to reaching movements in aging humans are not well understood. Objective To better understand the role of cortical motor regions and age on the control of unconstrained reaches against gravity by neurologically intact, younger and older adults. Methods Dou...
Preprint
Full-text available
Reaching for an object in space forms the basis for many activities of daily living and is important in rehabilitation after stroke and in other neurological and orthopedic conditions. It has been the object of motor control and neuroscience research for over a century, but studies often constrain movement to eliminate the effect of gravity or redu...
Article
Background Dravet Syndrome (DS) is a developmental and epileptic encephalopathy starting in infancy and characterised by treatment resistant epilepsy with cognitive impairment and progressive motor dysfunction. Walking becomes markedly impaired with age, but the mechanical nature of gait problems remains unclear. Research question What are the kin...
Article
Aim To investigate the relation between cognitive and motor development in preschool aged children with Dravet syndrome, in particular between the age of independent walking and cognitive development. Method Results of cognitive and motor developmental assessments and the age of independent walking were retrieved retrospectively from the medical r...
Poster
Full-text available
Cluster analysis on kinematic parameters of gait identified 3 clusters showing 3 distinct gait patterns in Dravet. The previously reported crouch pattern was confirmed as well as a highly functional gait pattern with only mild deformities. The third pattern is characterised by substantial rotational deformities in the transverse plane at the level...
Article
Background: Clinical laboratory testing of locomotor disorders is challenging in patients with intellectual disability (ID). Nevertheless, also in this population gait analysis has substantial value as motor problems are common. To promote its use, adequate protocols need to be developed and the impact on clinical decision making needs to be docum...
Article
Background Dravet Syndrome is a rare developmental and epileptic encephalopathy characterised by epileptic seizures, cognitive impairment and motor disorders. Gait is markedly impaired and could benefit from targeted intervention to improve quality of life for patient and caregivers. Objective To establish the state of the art regarding gait devi...

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Projects

Project (1)
Project
The ultimate goal of this project is to improve mobility and quality of life in children, adolscents and adults with the syndrome of Dravet, a very severe infantile-onset epilepsy syndrome. To reach this goal, a better understanding of the biomechanical and neurological causes of the observed gait deterioration is necessary.