Lisa Berlin Thorell

Karolinska Institutet | KI · Department of Clinical Neuroscience

Background The notion that ADHD constitutes a heterogeneous disorder is well accepted. However, this study contributes with new important knowledge by examining independent effects of a large range of neuropsychological deficits. In addition, the study investigated whether deficits in emotional functioning constitute a dissociable component of ADHD...

Introduction Previous research has shown that Attention-Deficit Hyperactivity Disorder (ADHD) is linked to emotion dysregulation, but we still do not know enough about the specific nature of this deficit. The aim of the present study was therefore to study emotion dysregulation in adult ADHD using a new self-rating instrument, the Comprehensive Emo...

The aim of the present study was to examine parental experiences of homeschooling during the COVID-19 pandemic in families with or without a child with a mental health condition across Europe. The study included 6720 parents recruited through schools, patient organizations and social media platforms (2002 parents with a child with a mental health c...

The aim of this open non-controlled clinical trial was to investigate the feasibility and preliminary treatment effects of a new group-based skills training program for adult ADHD: Group Therapy for Improving Emotional Acceptance and Regulatory Skills in Adults with ADHD (GEARS). Out of the 226 allocated patients, 213 initiated the treatment and 17...

Aim To study if a specific cognitive profile can be identified for children born extremely preterm (EPT) by investigating: 1) strengths and weaknesses not revealed by Full‐Scale IQ, 2) overlap between different cognitive deficits and 3) proportion of EPT children with multiple deficits. Methods We analyzed data from the 4th version of Wechsler Int...

Introduction Although not yet recognized as an official disorder, Social Media Disorder (SMD) has recently received considerable interest in the research. However, relatively little is known about underlying motives for social media use and to what extent motives show differential associations with SMD symptom severity and SMD diagnosis. The overal...

Objectives This qualitative study explored the perceptions of adult clients participating in a new psychological treatment for attention-deficit/hyperactivity disorder inattentive presentation (ADHD-I, also called “attention deficit disorder”, ADD). The study aimed to explore (i) what aspects of treatment the participants found to be helpful, and (...

One of the greatest COVID-19-related challenges for children and their families was managing distance learning due to school closures. We also know from previous research that families with a child with a neurodevelopmental disorder such as ADHD or ASD were struggling more than others but also experienced some positive effects. However, few qualita...

One of the greatest COVID-19 related challenges for children and their families was managing distance learning due to school closures. We also know from previous research that families with a child with a neurodevelopmental disorder such as ADHD or ASD were struggling more than others, but also experiences some positive effects. However, few qualit...

Introduction This study examined associations between screen time and addictive use (i.e., heavy involvement and negative consequences) of gaming and social media, and their independent effects on health outcomes. Methods Survey data were collected from 2,265 participants (mean age = 21.57). Internet Gaming Disorder (IGD) and Social Media Disorder...

While studies have reported effects on digital media during the COVID-19 restrictions, few have included data prior to the pandemic, and most have only measured screen time. We therefore investigated changes in specific digital media activities, as well as mental health and lifestyle habits, in a longitudinal study of adolescents spanning from befo...

Currently, there is no screening instrument available for assessing both internet gaming disorder (IGD) and social media disorder (SMD). This study aimed to examine the reliability and factor structure of a new screening instrument for adolescents and adults, the Gaming and Social Media Questionnaire (GSMQ-9), and to investigate its association wit...

Background and aims: It has been argued that it is important to consider underlying mechanisms of mental health problems. Previous studies have shown that executive deficits, delay aversion, and emotion dysregulation are related to Internet Gaming Disorder (IGD) and Social Media Disorder (SMD). However, the present study is the first to investigat...

Introduction: This study examined the psychometric properties of the Adult Executive Functioning Inventory (ADEXI) in a sample of Iranians. This executive functioning (EF) rating instrument has the advantage of being brief (14 items) and focusing specifically on working memory and inhibitory control. Methods: In Iran, the participants were 250 typi...

Previous reviews have often shown a link between digital media ADHD symptom levels. However, longitudinal studies are needed to find stronger evidence of a causal effect as well as to determine the direction of effects. The aim of the present review (PROSPERO CRD42021262695) was therefore to provide a systematic review of studies meeting the follow...

Background One of the COVID-19 pandemic consequences that has affected families the most is school lockdowns. Some studies have shown that distance learning has been especially challenging for families with a child with neurodevelopmental disorders such as ADHD or ASD. However, previous studies have not taken the heterogeneity of these disorders in...

Importance: Early detection of attention-deficit/hyperactivity disorder (ADHD) plays a crucial role in reducing negative effects on everyday life, including academic failure and poor social functioning. Children who survive ischemic strokes risk major disabilities, but their risk of ADHD has not been studied in nationwide cohorts. Objective: To...

Attention-deficit/hyperactivity disorder (ADHD) is a highly impairing condition with varying clinical presentations. Psychological treatments for ADHD are often similar, irrespective of predominant symptomatology. However, because inattention and hyperactivity/impulsivity are associated with different challenges in daily life more presentation-spec...

Background: The Childhood Executive Functioning Inventory (CHEXI) was designed to identify EF deficits in daily life contexts. The aim of the present study was to validate the Spanish version of the CHEXI in 4-5-year-old children. Method: Parents’ ratings of the CHEXI and laboratory tests of EF were investigated in two large samples of 445 children...

This report was written to compile the scientific evidence on possible links between digital media and mental health problems in children and adolescents. This was part of the Swedish Media Council's contribution to the development of the Swedish government's national strategy to tackle mental health problems.

Background: During the COVID-19 pandemic, both children and their parents experienced consequences related to distance learning (DL). However, positive and negative effects have varied greatly among families, and the specific factors explaining these differences in experiences are still underexplored. In this study, we examined children's executive...

The COVID-19 pandemic has created an unusually stressful situation for many people around the world. Due to the restrictions, many have been isolated in their homes, and having a responsive partner may have become even more important. The present study aimed to investigate (1) whether there were any differences in social and work-related stressors...

Background: Previous research has shown that addictions to digital media can have negative impact on psychosocial health. Although Internet Gaming Disorder (IGD) has received most scholarly recognition, the potential negative consequences of Social Media Disorder (SMD) have also been found. However, few studies have assessed the symptoms of these t...

INVENTARIO DE FUNCIONAMIENTO EJECUTIVO PARA ADULTOS (ADEXI) VERSIÓN HETERO-INFORME https://chexi.se/downloads

The aim of the present study was to investigate the psychometric properties of the Spanish version of the Adult Executive Functioning Inventory (ADEXI) in adults with Autism Spectrum Disorders (ASD) and Intellectual Disability (ID). A total of 121 adults with ASD and ID were recruited and informant ratings on the ADEXI were collected to investigate...

Many students with ADHD experience educational attainment difficulties. Nevertheless, evidence-based classroom management strategies (CMS) are seldom used. This science-practitioner gap might be due to a lack of shared knowledge between the scientific fields of psychology/psychiatry and education. This review uses science mapping to explore the bas...

Objective measurements of ADHD symptom levels can be a highly valuable complement to ratings. However, sometimes it is not feasible to bring patients into the clinic/lab for assessment. The aim of the present study was therefore to evaluate the psychometric properties of the QbCheck, an online computerized test that measures errors and reaction tim...

The Childhood Executive Functioning Inventory (CHEXI) and the Adult Executive Functioning Inventory (ADEXI) are reliable and valid rating instruments for assessing working memory and inhibitory control. However, a teenage version of this instrument has not been available, and the aim of the present study was therefore to investigate the psychometri...

Attention-deficit/hyperactivity disorder (ADHD) is related to multiple neuropsychological deficits. However, most previous studies, especially studies of adult samples, have not taken the overlap between different neuropsychological deficits into account. In addition, the link between neuropsychological deficits and daily life functioning and quali...

Objectives We investigated whether a school-based physical activity intervention would lead to improvements in working memory, inhibition and cognitive flexibility in adolescents aged 13–15 years. Methods The adolescents at the active school ( n = 108) participated in an intervention that included increased physical activity for 20 min/day, focuse...

Assessment of executive functions (EF) is often criticized for its lack of ecological validity. As a consequence, several self- and partner rating scales for EF have been developed, while rating scales designed for clinicians are lacking. We therefore developed the Executive Checklist (EC-10), a new rating scale for clinicians assessing dysexecutiv...

Purpose and aim: The overall aim of the present study was to examine quality of life in attention deficit hyperactivity disorder (ADHD) patients age ≥60 years. First, we compared older adults with ADHD to both healthy controls of the same age and younger adults with ADHD. Second, we examined executive functioning as a possible underlying factor for...

The aim of the present study was to investigate daily life functioning in adults with ADHD and adults with other psychiatric disorders and to compare ADHD subgroups with or without executive deficits. Daily life functioning was assessed using self-ratings covering the following domains: academic/occupational functioning, social relations, daily lif...

Background: Diagnostic guidelines recommend using a variety of methods to assess and diagnose ADHD. Applying subjective measures always incorporates risks such as informant biases or large differences between ratings obtained from diverse sources. Furthermore, it has been demonstrated that ratings and tests seem to assess somewhat different constr...

Purpose: The Conners Rating Scales are widely used in research and clinical practice for measuring attention deficit/hyperactivity disorder (ADHD) and associated problem behaviors, but country-specific norms are seldom collected. The current study presents the standardization of the Swedish Conners 3® Rating Scales. In addition, we compared the Swe...

The present study aimed at improving our understanding of the role of neuropsychological deficits in preschool Attention Deficit Hyperactivity Disorder (ADHD). The study included 52 children in the ADHD group and 72 controls (age 4–6 years). Both laboratory measures and teacher reports of executive deficits (i.e., working memory, inhibition, and sh...

The aim of the present study was to investigate the interplay between attention deficit hyperactivity disorder (ADHD) symptoms and emotional functioning in relation to peer problems. Parent ratings of ADHD symptoms and regulation/reactivity with regard to four emotions (anger, sadness, fear, and happiness/exuberance) at age six were investigated in...

This study aimed to examine relations between parent and child attachment representations and neuropsychological functions at age 8, as well as relations between these constructs and ADHD symptoms over a 10-year period. A community-based sample of 105 children (52 boys) participated. Measures of attachment representations and a range of neuropsycho...

Objective Neuropsychological deficits are of major importance in ADHD, yet no previous studies have assessed clinically referred samples of older adults. The authors compared older adults with ADHD (60–75 years) with both younger adults with ADHD (18–45 years) and older healthy controls with regard to various neuropsychological deficits. Methods W...

This study examined the psychometric properties of the Adult Executive Functioning Inventory (ADEXI). This new executive functioning (EF) rating instrument has the advantage of being brief (14 items) and focusing specifically on working memory and inhibitory control. Results showed that scores on the ADEXI had high internal consistency and adequate...

Objective: The aim was to investigate how well neuropsychological measures can discriminate between adults with ADHD and those with other psychiatric disorders. Method: Adults with ADHD and a clinical control group ( n = 110) were included. Neuropsychological functioning was investigated using measures of inhibition, working memory, set shifting...

The Quick Delay Questionnaire (QDQ) is a self-report measure of delay-related behaviors in adults, and the present study aimed at investigating the psychometric properties of QDQ scores, how well they can discriminate between ADHD adults and both clinical and nonclinical controls, as well as their relations to measures of functional impairments. In...

High levels of ADHD symptoms are related to severe negative outcomes, which underscore the importance of identifying early markers of these behavior problems. The main aim of the present study was therefore to investigate whether neuropsychological deficits in preschool are related to later ADHD symptoms and academic achievement, over and above the...

In this study, we aimed to replicate Stattin and Kerr's (2000) study on parental monitoring and adolescents' deviant behavior, to extend their findings to ADHD symptoms, and to examine the longitudinal predictors (8–18 years) of parental knowledge and child disclosure. Results showed that conduct problems were primarily associated with parental kno...

There is a trend toward diagnosing ADHD prior to school entry. Despite this, there is a lack of studies investigating ADHD in the preschool years, at least studies including a large range of different neuropsychological functions. Our knowledge of the independent effects of different neuropsychological functions in relation to preschool ADHD is the...

Attention deficit hyperactivity disorder (ADHD) is associated with multiple neuropsychological deficits and the present study aimed to investigate to what extent these deficits are related to the functional impairments associated with the disorder. The results showed that all executive functioning deficits and reaction time variability acted as med...

The overall aim of the present study was to investigate ADHD symptoms in relation to attachment representations. We used both attachment- and non-attachment-related story stems, which allowed us to investigate whether problems with narrative production can explain the relation between ADHD symptoms and attachment representations. We also investigat...

The strong association between deficits in executive functioning (EF) and psychiatric disorders such as Attention-Deficit Hyperactivity Disorder (ADHD) has led to the development of a myriad of neuropsychological tests designed to capture both executive functioning in general and specific abilities within the EF domain. However, relatively few EF r...

Objective: The aim was to investigate the psychometric characteristics of the French adaptation of the Childhood Executive Functioning Inventory (CHEXI) in children and to explore the cross-cultural validity of the CHEXI in discriminating between children with ADHD and controls in two culturally different samples (Belgian and Swedish). Method: Stud...

The present study investigated the relation between academic performance and ratings of executive functioning in children aged 6-11 from four countries: Sweden, Spain, Iran, and China. Ratings of executive functioning were made by both parents and teachers using the Childhood Executive Functioning Inventory (CHEXI). The results showed that the Chin...

This study investigated attachment representations and executive functioning (i.e., response inhibition and working memory) at age 8½ in relation to ADHD symptoms one year later. Well-validated laboratory measures of both executive functioning and attachment representations were used. Additive, interaction, as well as mediation effects were investi...

En el presente estudio se investiga la capacidad predictiva de las puntuaciones de funcionamiento ejecutivo de niños preescolares obtenidas a la edad de 4 años, sobre las habilidades matemáticas básicas evaluadas 12 meses después. Inicialmente, las puntuaciones de funcionamiento ejecutivo fueron obtenidas a través del Childhood Executive Functionin...

The aim of the present study was to investigate whether attachment insecurity, focusing on disorganized attachment, and the executive function (EF) component of inhibition, assessed at age 5, were longitudinally related to general externalizing problem behaviors as well as to specific symptoms of ADHD and Autism spectrum disorder (ASD), and callous...

Fluid intelligence (Gf) predicts performance on a wide range of cognitive activities, and children with impaired Gf often experience academic difficulties. Previous attempts to improve Gf have been hampered by poor control conditions and single outcome measures. It is thus still an open question whether Gf can be improved by training. This study in...

The present study, including children at risk for developing Attention Deficit Hyperactivity Disorder (ADHD), examined the idea that complex executive functions (EFs) build upon more simple ones. This notion was applied in the study of longitudinal interrelations between core EF components - simple and complex inhibition, selective attention, and w...

Based on formulations about the possible consequences for adaptation of gender nonnormative behaviour, we investigated predictive and concurrent relations of hyperactivity and shyness to various aspects of adaptation focusing on possible effects of sex. At ages 5-6, parents and preschool teachers rated hyperactivity and shyness for 151 children (50...

The present study is the first European evaluation of the Canadian parent training programme called Community Parent Education Program (COPE). In addition, it is the first to examine the effects of the COPE programme in different types of clinical and nonclinical samples. The main findings were that COPE was found to be effective in reducing conduc...

The present study investigated whether the Childhood Executive Function Inventory (CHEXI) can discriminate between young children fulfilling the diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) and normally developing children. Unlike other executive function rating instruments, the CHEXI focuses specifically on inhibitory co...

Executive functions, including working memory and inhibition, are of central importance to much of human behavior. Interventions intended to improve executive functions might therefore serve an important purpose. Previous studies show that working memory can be improved by training, but it is unknown if this also holds for inhibition, and whether i...

The aim of the present study was to investigate different neuropsychological impairments and comorbid behavioral problems in relation to symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD), studying the independent effects of different functions as well as specific relations to symptoms of hyperactivity/impulsivity and inattention. A commun...

Previous research has shown that children with high levels of attention-deficit/hyperactivity disorder (ADHD) symptoms often have a wide variety of associated behaviour problems. However, relatively little is known regarding to what extent these associated behaviour problems are present to the same degree in younger as well as older children and in...

This study investigates children's views on positive and negative effects of stimulant medication for ADHD and the children's willingness to stop taking medication. Questionnaire data were collected from 79 children with ADHD and one of each child's parents. Swedish children treated with stimulants generally experienced positive treatment effects i...

Behavioural findings indicate that the core executive functions of inhibition and working memory are closely linked, and neuroimaging studies indicate overlap between their neural correlates. There has not, however, been a comprehensive study, including several inhibition tasks and several working memory tasks, performed by the same subjects. In th...

The present study investigated how task difficulty can be manipulated in inhibitory control tasks. Tasks from three widely used task paradigms - a Go/No-Go task, a Stop-Signal task,and a Flanker task - were manipulated on two parameters each (Go/No-Go task: interstimulus interval, prepotency. Stop-signal task: stop-signal-delay, prepotency. Flanker...

Poor executive functioning has been shown to be of central importance in disruptive behavior disorders such as attention deficit hyperactivity disorder (ADHD), and a large number of laboratory measures of executive functioning have been developed. There are, however, few available questionnaires tapping executive functioning and those that exist al...

This longitudinal study investigated ADHD symptoms and EF impairments in terms of continuity and cross-domain associations, as well as their predictive relations to a range of socioemotional problem behaviors. We applied a factorial ANOVA design to study additive and interactive effects in a sample of non-clinical preschool children (N = 87) and co...

The main aim of this study was to investigate the developmental course of motor response inhibition and execution as measured by the stop-signal task in a population-based sample of 525 4- to 12-year-olds. A further aspiration of the study was to enhance the limited knowledge on how the various stop-signal measures relate to ADHD behaviors in a nor...

The present study examined the distinct properties of executive functioning in relation to ADHD symptoms, as well as functional outcomes associated with ADHD. In line with the dual-pathway model of ADHD, executive functioning and delay aversion were expected to show independent effects on ADHD symptoms. Furthermore, relations to early academic skil...

The aim of the present study was to investigate how three different types of inhibitory control - interference control within task, interference control outside task, and prepotent response inhibition - and two types of working memory - verbal and spatial - would relate to early symptoms of attention deficit/hyperactivity disorder (ADHD) and opposi...

Relations between child self-reports of specific aspects of emotion regulation and specific aspects of social functioning in school were studied in two samples (N = 129/135) of 8- to 9-year-old children. The newly developed child self-report measure had significant relations to parent (Sample 1) and teacher (Sample 2) ratings of emotion regulation....

This study examined the predictive relations from symptoms of Attention-deficit/hyperactivity disorder (ADHD) and executive functioning (EF) to social and school functioning in 112 (62 girls) school children. High levels of teacher and parent ratings of ADHD symptoms at the ages of 8-8 1/2 years, and poor EF measured at the age of 8 1/2, were assoc...

The present study investigated the relation between executive functioning and symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) and Oppositional Defiant Disorder (ODD) in children aged 4–6. A population-based sample (n=201) was used and laboratory measures of inhibition, working memory and verbal fluency and teacher ratings of disruptive...

In a group of 112 children (46% boys), representations of attachment to parents and shyness at age 5 were used as predictors of social relationships in preschool at age 6. A Story Completion task was used to assess attachment representations and shyness was assessed through parent ratings and observations. Preschool teachers rated the child-teacher...

The aim was to investigate two inhibitory concepts—executive inhibition and inhibition to the unfamiliar. The relation between these two phenomena was studied as well as how they, alone or in combination, are related to the development of hyperactivity, social anxiety, and social competence. The results showed that there was a low, positive relatio...

The aim of the present study was to evaluate the usefulness of Barkley's (1997a) model of inhibition and executive functioning in describing the deficits associated with Attention Deficit Hyperactivity Disorder (ADHD). Besides group differences, the present study addressed the question of independent effects of inhibition and the other executive fu...

The present study examined whether inhibition measured as early as preschool can predict more general executive functioning and ADHD symptoms at school age. In contrast to previous studies, the present study focused specifically on ADHD symptoms rather than general disruptive behavior problems, and boys and girls were studied separately. The main r...

To study sustained performance and its relation to regulation of effort among four different groups of children: two clinical subgroups of children diagnosed with attention-deficit hyperactivity disorder (ADHD)--one with and one without comorbid oppositional defiant disorder (ODD); a control sample of children without a diagnosis of ADHD but with p...