Lisa Nobel

• Doctor of Philosophy
• Resident physician at University of Massachusetts Chan Medical School

Abstract Background: Bilateral posterior cerebral artery (PCA) occlusions are exceedingly rare, and are considered a devastating phenomenon that presents as cortical blindness. Predominant causes of PCA infarcts include cardiac and arterial embolisms. Left ventricular noncompaction (LVNC) cardiomyopathy is also an extremely rare cardiopathology. S...

Importance Studies to date have not comprehensively examined pain experience after total knee arthroplasty (TKA). Discrete patterns of pain in this period might be associated with pain outcomes at 6 to 12 months after TKA. Objectives To examine patterns of individual post-TKA pain trajectories and to assess their independent associations with long...

Objectives: To examine the association between maternal diet quality and infant weight for length growth trajectory during their first year of life. Methods: Participants were singleton infant-mother pairs (N = 77) enrolled in the Pregnancy and Postpartum Observational Dietary Study. Mothers completed socio-demographics and dietary (24-hour reca...

Objective: To explore the influence of contextual factors on health-related quality of life (HRQoL), which is sometimes used as an indicator of quality of care, we examined the association of neighborhood socioeconomic status (NSES) and trajectories of HRQoL after hospitalization for acute coronary syndromes (ACS). Methods: We studied 1481 patie...

Background: Childhood obesity is a major public health problem. Studies of patterns of child growth contributing to the development of obesity are scarce, particularly in infancy. Group based trajectory analyses among infants are a novel procedure that may help characterize subgroups of infants with similar longitudinal growth profiles. Objective:...

More than 1.2 million Americans are hospitalized annually with an acute coronary syndrome (ACS); many impaired quality of life after discharge with an ACS. This dissertation focuses on two novel aspects of patient health status (PHS) after ACS: how it can be predicted based on the socioeconomic status (SES) of the patient, and how it evolves over t...

Objective: We developed a measure of allostatic load from electronic medical records (EMRs), which we named "Index of Cardiometabolic Health" (ICMH). Methods: Data were collected from participants' EMRs and a written survey in 2005. We computed allostatic load scores using the ICMH score and 2 previously described approaches. Results: We inclu...

BACKGROUND: To describe longitudinal trajectories of health-related quality of life (HRQoL) after hospitalization with an acute coronary syndrome (ACS), their associations with baseline angina characteristics, and associations with anxiety, depression, and cognitive impairment. METHODS: TRACE-CORE participants (N=1,613) completed the SF-36 during h...

Unlabelled: Differentiating between superficial and deep-dermal (DD) burns remains challenging. Superficial-dermal burns heal with conservative treatment; DD burns often require excision and skin grafting. Decision of surgical treatment is often delayed until burn depth is definitively identified. This study's aim is to assess the ability of hyper...

Objective: The American Heart Association (AHA), recognizing critical knowledge gaps, has called for more research into determinants of patient functional status. We sought to identify longitudinal patterns (trajectories) of functional status and their predictors during 6 months following an acute coronary syndrome (ACS) discharge. Methods: We used...

Research Objective: Electronic medical records (EMRs) do not reconcile encounter diagnoses with patients’ problem lists (PLs), EMR PLs are typically not visually evident, reimbursement rules only incentivize recording diagnoses in claims, and there is no penalty for incomplete (or overcomplete) PLs. Thus, discrepancies between claims-based diagnose...

Background: Readmissions following acute myocardial infarction (AMI) are costly and may be partly due to poor care. A previous systematic review examined the literature through 2007. Since then, health policy has changed and additional articles examining predictors of readmission have appeared. We sought to conduct a systematic review of the litera...

Much of the excessive morbidity and mortality from cardiovascular disease among African Americans results from low adherence to anti-hypertensive medications. Therefore, we examined the association between weight-based discrimination and medication adherence. We used cross-sectional data from low-income African Americans with hypertension. Ordinal...

There is a variety of stroke risk factors, and engaging individuals in reducing their own personal risk is hugely relevant and could be an optimal dissemination strategy. The aim of the present study was to estimate the stroke risk for specific combinations of health- and lifestyle-related factors, and to develop a personalized stroke-risk assessme...

For engaging individuals in reducing personal stroke risk, knowledge about factors that are directly under individual control is relevant. Therefore, the objective was to estimate the risk of first ever stroke for specific combinations of health, lifestyle and psychological related factors. The regression equation, from a Cox proportional hazards m...