Lisa M Colosi

Lisa M Colosi
University of Virginia | UVa · Department of Civil and Environmental Engineering (CEE)

PhD

About

60
Publications
10,006
Reads
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2,679
Citations
Additional affiliations
July 2014 - present
University of Virginia
Position
  • Professor (Associate)
January 2008 - June 2014
University of Virginia
Position
  • Professor (Assistant)
August 2003 - December 2007
University of Michigan
Position
  • PhD Student
Education
August 2003 - December 2007
University of Michigan
Field of study
  • Environmental Engineering
September 1999 - May 2003
Cornell University
Field of study
  • Biological and Environmental Engineering

Publications

Publications (60)
Article
The widespread deployment of direct air capture is impeded by technology and scalability challenges, particularly resulting from high capital costs and energy demands. This paper posits that it is not possible to effectively evaluate the economic and environmental impacts of direct air capture without accounting for the spatial and temporal context...
Article
Antibiotic-resistant bacteria originating from hospitals are ultimately discharged to municipal wastewater treatment plants (WWTP), which may serve as important reservoirs for the spread of antibiotic resistant genes. This study traced and quantified the presence of a rare but clinically relevant antimicrobial resistance gene; Klebsiella pneumoniae...
Article
Antibiotic resistance genes (ARGs) in the effluents of wastewater treatment plants (WWTPs) may promote the selection of antibiotic resistance in downstream bacterial communities. This study evaluates the capacity of algae-mediated biological treatment, using the freshwater alga Scenedesmus dimorphus as a representative freshwater species, to deacti...
Article
Negative emissions technologies (NETs) that remove and store CO 2 from the atmosphere will play crucial roles in mitigating greenhouse gas emissions. Bioenergy with carbon capture and storage (BECCS) that combines biomass conversion for energy production and CO 2 capture and storage is a NET that has been intensively studied to meet climate goals....
Article
Full-text available
Wastewater-based monitoring for SARS-CoV-2 at individual building-level could be an efficient, passive means of early detection of new cases in congregate living settings, but this approach has not been validated. Preliminary samples were collected from a hospital and a local municipal wastewater treatment plant. Molecular diagnostic methods were c...
Article
Development of CO2 capture, utilization, and storage (CCUS) platforms has been deemed crucial for achievement of the Paris Agreement goals. Life-cycle assessment (LCA) is an important tool for assessing the efficacy of these technologies in achieving true net-carbon reduction. Critical review of previously published LCA-based evaluations of CCUS te...
Article
Deployment of bioenergy with CO2 capture and storage (BECCS) is projected to be crucial in reducing the United States’ CO2 emissions intensity. In this paper, we utilize a spatially explicit costing model to evaluate how regional biophysical factors and geography affect BECCS viability. We find that the cost of biomass provision and CO2 transport a...
Article
Biochar sequestration has gained increasing attention as a negative emissions technology to mitigate climate change. Although pyrolysis is a commercial technology, comprehensive environmental and economic assessments have been difficult to perform since biochar can be produced from a wide range of feedstocks and pyrolysis conditions. Many researche...
Preprint
Full-text available
Wastewater-based monitoring for SARS-CoV-2 holds promise as tool to inform public health-decision making. Testing at individual building-level could be an efficient, passive means of preventing early detection of new cases in congregate living settings, but this approach has not been validated. Sample collection protocols were developed and refined...
Article
It is anticipated that achievement of the Paris Climate Agreement goals will require widespread deployment of negative emission technologies (NETs). The most prominent NET is bioenergy with carbon capture and storage (BECCS), which is typically envisioned to use terrestrial crops as feedstock. Several recent studies have focused on aquatic BECCS (A...
Article
Full-text available
Development of coalbed methane (CBM) projects is critical to the achievement of climate change goals because it will help facilitate coal-to-gas transitions in Asia-Pacific countries with low conventional gas reserves. However, growth in CBM in these regions will necessitate strategic, sustainable approaches to produced water management. We posit t...
Article
Antibiotics in the effluents of municipal wastewater treatment plants (WWTP) may create selective pressures to induce antibiotic resistance in bacteria downstream. This study evaluates ciprofloxacin (CIP) removal by a freshwater alga, Scenedesmus dimorphus, to assess the efficacy of algae-based tertiary treatment in reducing effluent-induced CIP re...
Article
Full-text available
Hydrothermal liquefaction (HTL) is of interest in producing liquid fuels from organic waste, but the process also creates appreciable quantities of aqueous co-product (ACP) containing high concentrations of regulated wastewater pollutants (e.g., organic carbon, nitrogen (N), and phosphorus (P)). Previous literature has not emphasized characterizati...
Article
Full-text available
Bioenergy with carbon capture and storage (BECCS) has been proposed as a promising negative emission technology even though questions remain about the most effective ways to deploy it at large scale. Here, a comparative life cycle analysis of power plant configurations was conducted to understand the effect of three design parameters: (1) centraliz...
Poster
Most ensemble modeling projections of the 2°C target laid out at the Paris Climate Agreement include the deployment of negative emission technologies (NETs). The most prominent NET is bioenergy with carbon capture and storage (BECCS), which can be deployed on land and/or in coastal seas. To our knowledge, there has been no formal comparison of terr...
Poster
Produced water management is a key environmental question flanking coalbed methane (CBM) production. This is especially relevant because several coal/CBM producing basins have been known to face high water stress. Thus, while CBM is being targeted as a low-carbon fuel, it is desirable to make it less impactful on water systems of that area. We posi...
Article
Management of coalbed methane (CBM)-produced water is a crucial part of the water–energy nexus, especially as CBM is projected to play a key role as a bridge fuel in major economies. In this paper, we consider one management technique, i.e., desalination of CBM-produced water to generate potable water. We discuss a confluence of geographic, sociote...
Article
This research evaluates possible water impacts arising from creation of potent wastewaters during hydrothermal liquefaction (HTL) of organic wastes. Aqueous co-products (ACPs) arising from HTL of eight feedstocks contained very high concentrations of traditional wastewater pollutants: 100–3300 mg/L total nitrogen (N), 45–3600 mg/L total phosphorus...
Article
The environmental impacts of algae biofuels have been evaluated by life-cycle assessment (LCA); however, these analyses have overlooked nitrous oxide (N2O), a potent greenhouse gas. A literature analysis was performed to estimate algal N2O emissions and assess the impacts of growth conditions on flux magnitudes. Nitrogen source and dissolved oxygen...
Article
Water resource recovery facilities (WRRFs) are asked to improve both energy efficiency and nutrient removal efficacy. Integration of algaculture offers several potential synergies that could address these goals, including an opportunity to leverage anaerobic digestion at WRRFs. In this study, bench-scale experiments are used to measure methane yiel...
Article
The objective of this study is to elucidate the economic viability of algae-to-energy systems at a large scale, by developing a meta-analysis of five previously published economic evaluations of systems producing algae biodiesel. Data from original studies were harmonised into a standardised framework using financial and technical assumptions. Resu...
Article
The aviation sector relies almost exclusively on petroleum-derived fuels at the present time. Due to concerns including national security, long-term availability of crude oil feedstock, and environmental impacts, there is an increasing interest in identifying alternatives to conventional jet fuel. Viable alternatives must meet a number of criteria,...
Article
Life-cycle greenhouse gas (LC-GHG) emissions are a principal metric used by the US Environmental Protection Agency to determine whether a biofuel qualifies under the US EPA Renewable Fuel Standard (RFS2). This paper identifies important factors in the quantification of LC-GHG of algae-derived diesel, jet fuel, and gasoline, using hydrothermal lique...
Article
This study uses a systems-level modeling approach to illustrate a novel synergy between municipal wastewater treatment and large-scale algaculture for production of bio-energy, whereby algae-mediated tertiary treatment provides efficient removal of unregulated, strongly estrogenic steroid hormones from the secondary effluent. Laboratory results fro...
Article
This study illustrates a novel synergy between municipal wastewater treatment and large-scale algaculture for production of bio-energy; whereby, algae-mediated tertiary treatment provides efficient removal of unregulated, strongly estrogenic steroid hormones from the secondary effluent. Laboratory results indicate that a model algal strain (Scenede...
Article
The wastewater treatment field is increasing its emphasis on energy and resource recovery, while still prioritizing environmental protection. In this vein, there is growing interest in integration of algae cultivation and wastewater as a means to produce bioenergy while also removing dissolved nutrients. This paper assesses algae-mediated removal o...
Article
This study evaluates the social, economic, and environmental sustainability of ceramic filters impregnated with silver nano-particles for point-of-use (POU) drinking water treatment in developing countries. The functional unit for this analysis was the amount of water consumed by a typical household over ten years (37,960 L), as delivered by either...
Article
Life cycle assessment (LCA) has been used widely to estimate the environmental implications of deploying algae-to-energy systems even though no full-scale facilities have yet to be built. Here, data from a pilot-scale facility using hydrothermal liquefaction (HTL) is used to estimate the life cycle profiles at full scale. Three scenarios (lab-, pil...
Article
Full-text available
This research attempts to evaluate a previously developed model for predicting influent concentrations of prescription pharmaceuticals and understand why some drugs are more accurately predicted than others. It also investigates the impact of demographics on influent drug concentrations in municipal wastewater treatment plants (WWTPs). Samples from...
Article
The energy ratio metrics are increasingly important means of assessing the efficiency of energy production for emerging biofuels platforms, making comparisons among multiple alternatives, and formulating policies to foster commercialization of sustainable energy systems. However, these metrics are susceptible to inadvertent or meaningful mathematic...
Article
Quantitative molecular similarity analysis (QMSA) is a seemingly useful tool for estimating environmental properties for the hundreds of emerging contaminants that have not yet been fully evaluated. Moreover, calibrated QMSA models are also useful for prioritizing research among currently unmeasured chemicals of interest. Previous work has demonstr...
Article
Many current fate and transport models based on the assumption of instantaneous sorption equilibrium of contaminants in the water column may not be valid for certain pharmaceuticals with long times to reach sorption equilibrium. In this study, a sorption kinetics model was developed and incorporated into a water quality model for the Patuxent River...
Chapter
Algae-derived bioenergy is being widely discussed as a promising alternative to bioenergy produced from terrestrial crops. Several life cycle assessment (LCA) studies have been published recently in an effort to anticipate the environmental impacts of large-scale algae-to-energy systems. LCA is a useful tool for understanding the environmental impl...
Article
The widespread occurrence of the brominated flame retardant tetrabromobisphenol A (TBBPA) makes it a possible source of concern. Our experiments suggest that TBBPA can be effectively transformed by the naturally occurring laccase enzyme from Trametes versicolor. These reactions follow second-order kinetics, whereby apparent removal rate is a functi...
Article
Algae are an attractive energy source, but important questions still exist about the sustainability of this technology on a large scale. Two particularly important questions concern the method of cultivation and the type of algae to be used. This present study combines elements of life cycle analysis (LCA) and life cycle costing (LCC) to evaluate o...
Article
Life cycle assessment (LCA) has become an important tool for evaluating the environmental sustainability of proposed algae-to-energy systems. The rapidly evolving body of literature on this topic demonstrates several important lessons, which can be leveraged to evaluate the likely economic sustainability of future algae-derived energy sources. A re...
Article
The fate and transport of endocrine disrupting chemicals (EDCs) in ambient river waters is a major concern associated with effluents from municipal wastewater treatment plants (WWTPs). This paper presents a methodology for quantifying the spatial distribution of EDCs in a river mixing zone. The core of the technical analysis is based on a two-dimen...
Article
The very large number of emerging contaminants entering the water supply makes it desirable to assess these chemicals’ environmental fate and behavior without direct measurements. Structure–property prediction models are promising in this regard, and quantitative molecular similarity assessment (QMSA) is one particularly appealing option. This stud...
Article
A meta-analysis of several published life cycle assessments of algae-to-energy systems was developed to better understand the environmental implications of deploying this technology at large scales. Taken together, results from these six studies seemed largely inconclusive because of differences in modeling assumptions and system boundaries. To ove...
Article
Algae are a widely touted source of bioenergy with high yields, appreciable lipid contents, and an ability to be cultivated on marginal land without directly competing with food crops. Nevertheless, recent work has suggested that large-scale deployment of algae bioenergy systems could have unexpectedly high environmental burdens. In this study, a "...
Article
Several classes of oxidative enzymes have shown promise for efficient removal of endocrine disrupting compounds (EDCs) that are resistant to conventional wastewater treatments. Although the kinetics of reactions between individual EDCs and selected oxidative enzymes are well documented in the literature, there has been little investigation of react...
Article
We have verified in our previous work that lignin peroxidase (LiP) mediates effective removal of selected natural and synthetic estrogens. The efficiency of these reactions was greatly enhanced in the presence of veratryl alcohol (VA), a chemical that is produced along with LiP by certain white rot fungi, for example, Phanerochaete chrysosporium. I...
Article
A quantitative structure-activity relationship (QSAR) was used to streamline re-design of a model environmental catalyst, horseradish peroxidase (HRP), for enhanced reactivity towards a target pollutant, steroid hormone 17β-estradiol. This QSAR, embodying relationship between reaction rate and intermolecular binding distance, was used in silico to...
Conference Paper
The persistence and toxicity effects of endocrine-disrupting chemicals, including environmental estrogens, have not been well-characterized in wastewater treatment plant mixing zones. This study examines the levels of environmental estrogens present in the mixing zone of a shallow effluent-receiving stream in Charlottesville, VA and determines the...
Article
A mass balance model was developed to estimate prescription pharmaceutical loadings to municipal wastewater treatment plants via computation of influent concentrations (C IN). Model estimates of C IN were compared with published data and found to be accurate within an order of magnitude for some 90% of the drugs evaluated. The model was then used t...
Article
Full-text available
The sorption kinetics and equilibrium endpoints of two widely prescribed anionic lipid-regulating pharmaceuticals-atorvastatin and simvastatin acid-were evaluated for wastewater-treatment plant primary clarifier biosolids, a peat soil, a sandy soil, and a stream sediment. All equilibrium isotherms were linear over an aqueous concentration range of...
Article
Algae are an attractive source of biomass energy since they do not compete with food crops and have higher energy yields per area than terrestrial crops. In spite of these advantages, algae cultivation has not yet been compared with conventional crops from a life cycle perspective. In this work, the impacts associated with algae production were det...
Article
Full-text available
The gram-positive bacterial pathogen Listeria monocytogenes has evolved mechanisms to rapidly replicate in the host cytosol, implying efficient utilization of host-derived nutrients. However, the contribution of host nutrient scavenging versus that of bacterial biosynthesis toward rapid intracellular growth remains unclear. Nutrients that contribut...
Article
Concentrations of aqueous-phase perfluorooctanoic acid (PFOA), a representative perfluorinated aliphatic (PFA) compound, are shown to be reduced effectively via reaction with horseradish peroxidase (HRP), hydrogen peroxide, and a phenolic cosubstrate (4-methoxyphenol). Reaction rate profiles are pseudo-first order, yielding an apparent best-fit rem...
Article
Previously reported rates of reaction between six mutant strains of the enzyme horseradish peroxidase (HRP) and a test substrate, 2-methoxyphenol, were found to correlate with characteristic binding distances computed using molecular simulation. The correlation (R(2) = 0.86) bears out a working hypothesis that, based on a quantitative structure-act...
Article
Natural organic matter (NOM) of hydroxylated aromatic character can undergo catalyst-mediated self-coupling reactions to form larger molecular aggregates. Indeed, such reactions are central to natural humification processes. Nonhydroxylated persistent aromatic contaminants such as polychlorinated biphenyls (PCBs) are, conversely, inert with respect...
Article
The initial rates of horseradish peroxidase (HRP)-mediated enzymatic reactions of 15 assorted aqueous phase phenolic chemicals were studied. The associated reaction rate constants were found to correlate quantitatively with two independent variables: the highest-occupied molecular orbital energy (E(HOMO)) defining the intrinsic redox reactivities o...

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Projects

Projects (3)
Project
This project is funded through the David and Joy Peyton Fellowship for climate change research. It seeks to provide a concrete technological solution as well as a sustainability assessment framework to study the viability of direct air capture. Our objectives are: • ESTIMATE the current and projected amounts of excess renewable electricity in the US • EVALUATE the relative viability of the DAC to be powered through this excess generation through novel carbon reduction metrics • ENVISAGE early-adoption and commercialization of such concepts through currently available market incentives
Project
1. ENHANCING our understanding of the risk factors associated with energy transitions and incorporating these into life-cycle economic and environmental models of power supply. 2. ELUCIDATING these life-cycle results on a spatially-resolved basis to aid decision-making for various geographical regions. 3. ESTABLISHING a baseline model framework necessitated by the biophysical implications of these diverse, resilient energy systems.
Project
https://www.mdpi.com/journal/energies/special_issues/Life_Cycle_Assessment_Energy_Water We warmly welcome submissions advancing the knowledge base in this area, with special interest in the following topics, as they intersect the interrelationships between water and energy: 1. Environmental life cycle assessments (LCA) of present and future energy systems - Including LCAs for developing country scenarios - Including technological assessments for novel energy pathways; 2. Improvements in life-cycle methodologies or approaches - Incorporating novel impacts/endpoints for better characterization of environmental burdens - Incorporating spatially and/or temporally explicit data - Utilizing probabilistic frameworks for enhancing decision-making under high uncertainty; 3. Alternative systems frameworks to supplement or complement traditional LCA - Incorporating social perspectives in life-cycle studies - Utilizing cost-benefit analyses, techno-economic analyses, and/or energy footprint analyses.