
Lina MadaniyaziNagasaki University · Institute of Tropical Medicine
Lina Madaniyazi
PhD
About
86
Publications
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Introduction
Lina Madaniyazi currently works at the Nagasaki University as an Assistant Professor, focusing on the health impact of climate change and air pollution. I'm also a collaborative researcher of The Japan Environment and Children's Study (JECS) at National Institute for Environmental Studies.
Additional affiliations
November 2012 - April 2016
Publications
Publications (86)
BACKGROUND: Younger generations are projected to experience more severe climate exposure impacts during their lifetimes than older generations as global warming progresses. Despite the increasing evidence of the recent temporal changes in heat-related mortality risks, there remains a lack of research exploring this association from a cohort perspec...
Background
Tropical cyclones pose significant health risks and can trigger outbreaks of diarrheal diseases in affected populations. Although the effects of individual hazards, such as rainfall and flooding, on diarrheal diseases are well-documented, the complex multihazard nature of tropical cyclones is less thoroughly explored. To date, no dedicat...
With global temperatures rising, urban heat islands (UHIs) intensify heat exposure in cities, potentially elevating heat-related mortality. However, the specific burden of UHI-attributable mortality remains inadequately quantified. This study investigates the impact of UHIs on heat-related mortality in the Tokyo Metropolitan Area (TMA), Japan, from...
Objectives
While COVID-19 continues to challenge the world, meteorological variables are thought to impact COVID-19 transmission. Previous studies showed evidence of negative associations between high temperature and absolute humidity on COVID-19 transmission. Our research aims to fill the knowledge gap on the modifying effect of vaccination rates...
Background
Future temperature effects on mortality and morbidity may differ. However, studies comparing projected future temperature-attributable mortality and morbidity in the same setting are limited. Moreover, these studies did not consider future population change, human adaptation, and the variations in subpopulation susceptibility. Thus, we s...
Background
Evidence for long-term mortality risks of PM 2.5 comes mostly from large administrative studies with incomplete individual information and limited exposure definitions. Here we assess PM 2.5 -mortality associations in the UK Biobank cohort using detailed information on confounders and exposure.
Methods
We reconstructed detailed exposure...
Background
Diarrhoeal diseases cause a heavy burden in developing countries. Although studies have described the seasonality of diarrhoeal diseases, the association of weather variables with diarrhoeal diseases has not been well characterized in resource-limited settings where the burden remains high. We examined short-term associations between amb...
Background
We quantify the mortality burden and economic loss attributable to nonoptimal temperatures for cold and heat in the Central and South American countries in the Multi-City Multi-Country (MCC) Collaborative Research Network.
Methods
We collected data for 66 locations from 13 countries in Central and South America to estimate location-spec...
Introduction
A causal link between air pollution exposure and cardiovascular events has been suggested. However fewer studies have investigated the shape of the associations at low levels of air pollution and identified the most important temporal window of exposure. Here we assessed long-term associations between particulate matter < 2.5 µm (PM2.5...
Background
Precipitation could affect the transmission of diarrheal diseases. The diverse precipitation patterns across different climates might influence the degree of diarrheal risk from precipitation. This study determined the associations between precipitation and diarrheal mortality in tropical, temperate, and arid climate regions.
Methods
Da...
Background
Biomass burning (BB) is a major source of air pollution and particulate matter (PM) in Southeast Asia. However, the health effects of PM smaller than 10 µm (PM10) originating from BB may differ from those of other sources. This study aimed to estimate the short-term association of PM10 from BB with respiratory and cardiovascular hospital...
In this article, we present a comprehensive compilation of open access daily time-series datasets tailored to assess the temperature-mortality association. The data consists of daily mortality counts and average ambient temperature at various levels of geographic aggregation, including data from four cities, ten regions, and two counties, which hav...
Objectives: This study aims to estimate the short-term preventable mortality and associated economic costs of complying with the World Health Organization (WHO) air quality guidelines (AQGs) limit values for PM10 and PM2.5 in nine major Latin American cities.
Methods: We estimated city-specific PM-mortality associations using time-series regressio...
Tropical cyclones bring health risks and can trigger outbreaks of diarrheal diseases in affected populations. There are several reviews that mention the relationship between tropical cyclones and diarrheal diseases. However, there is no dedicated review of the current evidence and extent of research on the association between tropical cyclones and...
Background
Despite an unknown cause, Kawasaki disease (KD) is currently the primary leading cause of acquired heart disease in developed countries in children and has been increasing in recent years. Research efforts have explored environmental factors related to KD, but they are still unclear especially in the tropics. We aimed to describe the inc...
Background. Climate change can directly impact temperature-related excess deaths and might subsequently change the seasonal variation in mortality. In this study, we aimed to provide a systematic and comprehensive assessment of potential future changes in the seasonal variation, or seasonality, of mortality across different climate zones.
Methods....
Recent developments in linkage procedures and exposure modelling offer great prospects for cohort analyses on the health risks of environmental factors. However, assigning individual-level exposures to large population-based cohorts poses methodological and practical problems. In this contribution, we illustrate a linkage framework to reconstruct e...
Background:
The impact of temperature on morbidity remains largely unknown. Moreover, extensive evidence indicates contrasting patterns between temperature-mortality and temperature-morbidity associations. A nationwide comparison of the impact of temperature on mortality and morbidity in more specific subgroups is necessary to strengthen understan...
Background
Diarrhoeal diseases cause a heavy burden in developing countries. Although studies have described the seasonality of diarrhoeal diseases, the association of weather variables with diarrhoeal diseases has not been well characterized in resource-limited settings where the burden remains high. We examined short-term associations between wea...
Background
Heat stroke is a significant cause of mortality in response to high summer temperatures. There is limited evidence on the pattern and magnitude of the association between temperature and heat stroke mortality. We examined this association in Spain, using data from a 27-year follow-up period.
Methods
We used a space-time-stratified case–...
BACKGROUND AND AIM:The association between desert dust and daily mortality has been investigated previously in East Asia, but with a different analytical approach and methods for quantifying dust exposure, rendering it difficult to compare results with other regions. We conducted a study to examine the association using the European Union (EU) Refe...
BACKGROUND AND AIM: Diarrheal diseases continue to be a major disease burden in developing countries. Although studies described the seasonality of diarrheal diseases, the association of weather variables with diarrheal diseases has not been well characterized in resource-limited settings where the burden remains high. This study examines the short...
Background: Various rainfall conditions could promote the transmission of diarrhoeal diseases by affecting the pathogen concentration in the environment. Given the diversity of rainfall patterns across different climates, this study explored the associations between rainfall and diarrhoeal mortality in tropical, temperate, and arid regions.
Metho...
Ozone (O3)-induced health effects vary in terms of severity, from lung function deterioration, hospitalizations to death. Several studies have noted a linear increase in the health risk after O3 exposure. However, current evidence suggests a non-linear U- and J-shaped concentration-response (C-R) function. The potential increasing risks with decrea...
Background and aim
Short-term associations between air pollution and mortality have been well reported in Japan, but the historical changes in mortality risk remain unknown. We examined temporal changes in the mortality risks associated with short-term exposure to four criteria air pollutants in selected Japanese cities.
Methods
We collected daily...
Purpose
Otitis media with effusion (OME) is common in young children and is associated with Streptococcus pneumoniae infection. We aimed to determine the impact of pneumococcal conjugate vaccine (PCV) introduction on the prevalence of OME and OME associated with vaccine-type (VT) or non-VT.
Methods
Population-based cross-sectional surveys were con...
Several methods have been used to assess the seasonality of health outcomes in epidemiological studies. However, little information is available on the methods to study the changes in seasonality before and after adjusting for environmental or other known seasonally varying factors. Such investigations will help us understand the role of these fact...
Background:
Enteric infections cause significant deaths, and global projection studies suggest that mortality from enteric infections will increase in the future with warmer climate. However, a major limitation of these projection studies is the use of risk estimates derived from nonmortality data to project excess enteric infection mortality asso...
Background
Diphtheria cases reported in Central Vietnam since 2013 were mainly children aged 6-15 years, which may reflect an immunity gap. There is little information on diphtheria population immunity in countries without a school-entry booster dose. We aimed to measure the age-stratified seroprevalence of anti-diphtheria toxoid antibodies, quanti...
Air pollution has been associated with childhood neurodevelopment. However, the role of indoor air pollution, especially volatile organic compounds (VOCs), on childhood neurodevelopment has been poorly explored to date. We investigated the association between indoor air pollutants and childhood neurodevelopment in 5,017 randomly selected children f...
Background
During the COVID-19 pandemic, several illnesses were reduced. In Japan, heat-related illnesses were reduced by 22% compared to pre-pandemic period. However, it is uncertain as to what has led to this reduction. Here, we model the association of maximum temperature and heat-related illnesses in the 47 Japanese prefectures. We specifically...
Background
Ambient temperature may contribute to seasonality of mortality; in particular, a warming climate is likely to influence the seasonality of mortality. However, few studies have investigated seasonality of mortality under a warming climate.
Methods
Daily mean temperature, daily counts for all-cause, circulatory, and respiratory mortality,...
Background
Although seasonal variations in mortality have been recognized for millennia, the role of temperature remains unclear. We aimed to assess seasonal variation in mortality and to examine the contribution of temperature.
Methods
We compiled daily data on all-cause, cardiovascular and respiratory mortality, temperature and indicators on loc...
The nonpharmaceutical interventions (NPIs) on COVID-19 can impact current and future dynamics of respiratory syncytial virus infections (RSV). In Tokyo, RSV activity declined by 97.9% (95%CI: 94.8% - 99.2%) during NPIs. A longer period of NPIs could expand susceptible populations, enhancing the potential for larger RSV outbreaks after NPIs ends.
The high level of ambient particulate matter in many developing countries constitutes a major health burden, but evidence on its impact on children’s health is still limited in these regions. We conducted a time-stratified case-crossover analysis to quantify the short-term association between fine particulate matter (PM2.5) and hospital admissions...
Background
Mortality due to enteric infections is projected to increase because of global warming; however, the different temperature sensitivities of major enteric pathogens have not yet been considered in projections on a global scale. We aimed to project global temperature-attributable enteric infection mortality under various future scenarios o...
Objectives
To investigate the extent to which temperature and influenza explained seasonality of mortality in Japan and to examine the association of the seasonality with prefecture-specific characteristics.
Design
We conducted time-series analysis to estimate the seasonal amplitude before and after adjusting for temperature and/or influenza-like...
Exposure to outdoor air pollution has been consistently associated with asthma. In this study, we reviewed the epidemiological studies published within the last 5 years on the association between outdoor air pollution and exacerbation and onset of asthma. A large number of studies have been published within the last 5 years. Short-term exposure to...
The novel coronavirus, which was first reported in Wuhan, China in December 2019, has been spreading globally at an unprecedented rate, leading to the virus being declared a global pandemic by the WHO on 12 March 2020. The clinical disease, COVID-19, associated with the pandemic is caused by the pathogen severe acute respiratory syndrome coronaviru...
Supplemental Digital Content is available in the text.
China is implementing intensive policies on electric vehicles to control air pollution in urban regions, especially the Beijing–Tianjin–Hebei (BTH) region, one of the most polluted areas in China. The development of electric vehicles will lead to an increase in electricity demand. Because electricity is mostly generated by thermal power in China, p...
The first wave of COVID-19 epidemic began in late January in Malaysia and ended with a very small size. The second wave of infections broke out in late February and grew rapidly in the first 3 weeks. Authorities in the country responded quickly with a series of control strategies collectively known as the Movement Control Order (MCO) with different...
Background:
Potential adverse health effects of Asian dust exposure have been reported, but systematic reviews and quantitative syntheses are lacking.
Objective:
We reviewed epidemiologic studies that assessed the risk of mortality, hospital admissions, and symptoms/dysfunction associated with exposure to Asian dust.
Methods:
We performed a sy...
An amendment to this paper has been published and can be accessed via the original article.
Background:
Children are exposed to p,p'-dichlorodiphenyltrichloroethane (p,p'-DDT) and p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) through placental and lactational transfer. Some studies have suggested that early-life exposure to these compounds could lead to increased body mass index (BMI) during childhood. Our aim was to assess whether ch...
Background:
Epidemiological studies have linked air pollutant to adverse health effects even at low exposure levels, but limited evidence is available on its associations with gene expression levels.
Aim:
To investigate associations between air pollutants and gene expression levels.
Methods:
We collected data from Brisbane System Genetics Stud...
Few studies have been conducted to investigate the underlying mechanisms of the effect of temperature on cardiovascular disease at population level, especially among Chinese population. A total of 56,039 participants were recruited from Kailuan cohort study, China. The lipoprotein profile indicators, including triglycerides (TG), low-density lipopr...
Background:
The concentrations of ozone (O3) in China are increasing, especially in East China, but its future trends and potential health impacts remain to be explored.
Objectives:
The objective was to assess future trends in O3 concentrations and related premature death in East China between 2005 and 2030.
Methods:
First, a global chemical t...
We collected data from Kailuan cohort study from 2006 to 2011 to examine whether short-term effects of ambient temperature on heart rate (HR) and blood pressure (BP) are non-linear or linear, and their potential modifying factors. The HR, BP and individual information, including basic characteristics, life style, socio-economic characteristics and...
Estimating the burden of mortality associated with particulates requires knowledge of exposure-response associations. However, the evidence on exposure-response associations is limited in many cities, especially in developing countries. In this study, we predicted associations of particulates smaller than 10 μm in aerodynamic diameter (PM10) with m...
China is suffering from severe air pollution from fine particulate matter [≤2.5µm in aerodynamic diameter (PM2.5)], especially East China. But its future trends and potential health impacts remain unclear. The study objectives were to project future trends of PM2.5 and its short-term effect on mortality in East China by 2030. First, daily changes i...
Climate change may affect mortality associated with air pollutants, especially for fine particulate matter (PM2.5) and ozone (O3). Projection studies of such kind involve complicated modelling approaches with uncertainties.Objectives
We conducted a systematic review of researches and methods for projecting future PM2.5-/O3-related mortality to iden...