Limeng Yan

Limeng Yan
The University of Hong Kong | HKU · School of Public Health

MD, PhD

About

15
Publications
132,165
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2,582
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Introduction
So far, I have published the 3rd Yan Report to further prove lab-origin of SARS-CoV-2 on Zenodo. To note, the 2nd Yan report was removed by RG for “sensitive content”. If re-post it, RG would shut down my account (I have asked them the exact reason via email, unfortunately no response).

Publications

Publications (15)
Article
Full-text available
Influenza A viruses have multiple HA subtypes that are antigenically diverse. Classical influenza virus vaccines are subtype specific, and they cannot induce satisfactory heterosubtypic immunity against multiple influenza virus subtypes. Here, we developed a live attenuated H1N1 influenza virus vaccine that allows the expression of α-Gal epitopes b...
Article
We noted that the DCt values of severe cases were significantly lower than those of mild cases at the time of admission (appendix). Nasopharyngeal swabs from both the left and right nasal cavities of the same patient were kept in a sample collection tube containing 3 mL of standard viral transport medium. All samples were collected according to WHO...
Article
Full-text available
SARS-CoV-2, a novel coronavirus with high nucleotide identity to SARS-CoV and SARS-related coronaviruses detected in horseshoe bats, has spread across the world and impacted global healthcare systems and economy1,2. A suitable small animal model is needed to support vaccine and therapy development. We report the pathogenesis and transmissibility of...
Preprint
Full-text available
Abstract The COVID-19 pandemic caused by the novel coronavirus SARS-CoV-2 has led to over 910,000 deaths worldwide and unprecedented decimation of the global economy. Despite its tremendous impact, the origin of SARS-CoV-2 has remained mysterious and controversial. The natural origin theory, although widely accepted, lacks substantial support. Th...
Preprint
Full-text available
Abstract The origin of SARS-CoV-2 is a question that has attracted attention from all over the world. It has been portrayed by some as a great mystery, although the laboratory nature of this virus is evident to people with trained eyes. The fundamental reason for this current situation is a large-scale, multi-domain, deliberate scientific misinfor...
Preprint
Full-text available
A pandemic caused by the novel SARS-CoV-2 virus with high nucleotide identity to SARS-CoV and SARS-related coronaviruses detected in horseshoe bats is spreading across the world and impacting the healthcare systems and global economy1,2. A suitable small animal model is urgently needed to support the development of vaccines and antiviral treatments...
Article
Full-text available
Influenza viruses circulate worldwide causing annual epidemics that have a substantial impact on public health. This is despite vaccines being in use for over 70 years and currently being administered to around 500 million people each year. Improvements in vaccine design are needed to increase the strength, breadth, and duration of immunity against...
Article
Full-text available
Purpose:The effects of altered NFκB signaling in a corneal alkali burn model using mice with a deletion of the NFκB signaling modulator, RAP1(TERF2IP, Telomeric Repeat Binding Factor 2, Interacting Protein), were evaluated. The effects of this deletion on corneal resurfacing and neovascularization in this mouse model were examined. Methods:Corneal...
Article
Full-text available
The radiation-induced energy metabolism dysfunction related to injury and radiation doses is largely elusive. The purpose of this study is to investigate the early response of energy metabolism in small intestinal tissue and its correlation with pathologic lesion after total body X-ray irradiation (TBI) in Tibet minipigs. 30 Tibet minipigs were ass...
Article
Full-text available
Purpose: This study was undertaken to investigate the effects of recombinant human epidermal growth factor (rhEGF) and basic fibroblast growth factor (bFGF) on corneal wound healing and neovascularization (CNV). Methods: The positive effects of 10 ng/ml rhEGF and bFGF on the proliferation of corneal epithelial cells (SD-HCEC1s), rabbit keratocyt...
Article
Full-text available
This study was undertaken to assess the diagnostic value of 2-[18F]-fluoro-2-deoxy-D-glucose positron emission tomography with computed tomography ([18F]-FDG-PET/CT) in the detection of radiation toxicity in normal bone marrow using Tibet minipigs as a model. Eighteen Tibet minipigs were caged in aseptic rooms and randomly divided into six groups....

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