Lijie Yang

Lijie Yang
Vanderbilt University | Vander Bilt · Department of Mechanical Engineering

PhD

About

10
Publications
1,444
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414
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Publications

Publications (10)
Article
Full-text available
The complex neuronal circuitry connected by sub-micron synapses in our brain calls for technologies that can map neural networks with ultrahigh spatiotemporal resolution to decipher the underlying mechanisms for multiple aspects of neuroscience. Here we show that through combining graphene transistor arrays with scanning photocurrent microscopy, we...
Article
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Cancer-associated fibroblasts (CAFs) are major components of the carcinoma microenvironment that promote tumor progression. However, the mechanisms by which CAFs regulate cancer cell migration are poorly understood. In this study, we show that fibronectin (Fn) assembled by CAFs mediates CAF–cancer cell association and directional migration. Compare...
Article
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Caenorhabditis elegans (C. elegans) is a powerful model organism extensively used in studies of human aging and diseases. Despite the numerous advantages of C. elegans as a model system, two biological characteristics may introduce complexity and variability to most studies: 1. it exhibits different biological features, composition and behaviors at...
Article
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Most investigations of cancer-stroma interactions have focused on biochemical signaling effects, with much less attention being paid to biophysical factors. In this study, we investigated the role of mechanical stimuli on human prostatic fibroblasts using a microfluidic platform that was adapted for our experiments and further developed for both re...
Article
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Abstract Cell migration is fundamental to a variety of physiological processes, including tissue development, homeostasis, and regeneration. Migration has been extensively studied with cells on two-dimensional (2D) substrates, but much less is known about cell migration in 3D environments. Tissues and organs are 3D, which is the native environment...
Article
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Background Maternal immune activation and subsequent interleukin-6 (IL-6) induction disrupt normal brain development and predispose the offspring to developing autism and schizophrenia. While several proteins have been identified as having some link to these developmental disorders, their prevalence is still small and their causative role, if any,...
Article
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We propose to monitor the liquid-solid and gas-liquid phase transition of water based on FBG sensors. The naked FBGs and the packaged FBG temperature sensors are used to monitoring the liquid-solid phase transition of water at the same time in order to find its characteristics, including the supercooling state and the strain and pressure change int...
Article
In light of the function of air accumulator on balancing peak load and stabilizing air supply parameters, it has been widely used in compressed air system. In this paper, operating characteristic and performance of air accumulator in the inflating condition of constant inlet pressure or flow rate was obtained via experimental research. In addition,...

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