Lidia Ferrer-Tasies

Lidia Ferrer-Tasies
Materials Science Institute of Barcelona · Molecular Nanoscience and Organic Materials

About

12
Publications
1,489
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
316
Citations

Publications

Publications (12)
Article
Molecular self-assembly has enabled the fabrication of biologically inspired, advanced nanostructures as lipid-based nanovesicles (L-NVs). The oldest L-NVs, liposomes, have been widely proposed as potential candidates for drug delivery, diagnostic and/or theranostic applications and some liposome-based drug products have already stepped from the la...
Article
Thermodynamically stable nanovesicular structures are of high interest for academia and industry in a wide variety of application fields, ranging from nanomaterials preparation to nanomedicine. Here we show the ability of quaternary ammonium surfactants and sterols to self-assemble forming stable amphiphilic bimolecular building-blocks with the app...
Article
Full-text available
Diabetes mellitus remains as a pandemic disease, associated to progressive and irreversible complications including lower extremity ulcerations, derived from a predisposition to ischemia, neuropathy and an intrinsic wound healing failure. The molecular operators supporting wound chronicity remain elusive, but a local deficit of growth factors is in...
Article
Full-text available
Topical delivery has received great attention due to its localized drug delivery, its patient compliance, and its low risk for side effects. Recent developments have focused on studying new drug delivery systems as a strategy for addressing the challenges of current topical treatments. Here we describe the advances on an innovative drug delivery pl...
Article
In article number 2000260, Jaume Veciana, Nora Ventosa and co‐workers report a soft, reliable, and scalable method based on compressed CO2 for obtaining nanoconjugates of recombinant human epidermal growth factors and nanovesicles. These nanoconjugates exhibit appropriate physicochemical properties together with an antimicrobial activity preventing...
Article
Full-text available
A multitude of microparticles and nanoparticles is developed to improve the delivery of different small drugs and large biomolecules, which are subject to several hindering biological barriers that limit their optimal biodistribution and therapeutic effects. Here, a soft, reliable, and scalable method based on compressed CO2 is reported for obtaini...
Article
Quatsomes are outstanding new lipid-based nanovesicles that are highly homogeneous and stable in different media for years, but the composition must be carefully chosen to avoid any potentially toxic side effects in in vivo applications. To this end, we have developed and studied a novel type of Quatsomes composed of cholesterol and myristalkonium...
Article
Full-text available
Correction for ‘Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics’ by Marina I. Giannotti et al. , Nanoscale , 2018, 10 , 14763–14770.
Article
Quatsomes (QS) are unilamellar nanovesicles constituted by quaternary ammonium surfactants and sterols in defined molar ratios. Unlike conventional liposomes, QS are stable upon long storage such as for several years, they show outstanding vesicle to vesicle homogeneity regarding size and lamellarity, and they have the structural and physicochemica...
Article
Full-text available
Cell processes like endocytosis, membrane resealing, signaling and transcription, involve conformational changes which depend on the chemical composition and the physicochemical properties of the lipid membrane. The better understanding of the mechanical role of the lipids in cell membrane force-triggered and sensing mechanisms has recently become...
Article
Fluorescent silicon (Si) nanocrystals (2.8 nm diameter) were incorporated into surfactant assemblies of cetyl trimethylammonium bromide (CTAB) and cholesterol, called quatsomes. In water, the quatsome-Si nanocrystal assemblies remain fluorescent and well-dispersed for weeks. In contrast to Si nanocrystals, alkanethiol-capped gold (Au) nanocrystals...
Article
There is a large interest in finding non-lipid building-blocks or tectons, which self-assemble into stable vesicles, and which satisfy the quality standards required in pharmaceutical formulations. Here we show the ability of quaternary ammonium surfactants and sterols to self-assemble forming stable amphiphilic bimolecular building-blocks with the...

Network

Cited By