Leslie Miller-Robbie

Leslie Miller-Robbie
University of Colorado | UCD · Department of Civil Engineering

PhD
Researcher at Colorado School of Mines

About

15
Publications
4,120
Reads
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615
Citations
Additional affiliations
August 2017 - present
University of Colorado
Position
  • Lecturer
August 2015 - August 2016
Humboldt State University
Position
  • Professor
January 2015 - May 2015
Colorado School of Mines
Position
  • Lecturer
Education
January 2009 - May 2011
University of Colorado
Field of study
  • Civil Engineering Systems
August 2006 - December 2008
University of Colorado
Field of study
  • Environmental Engineering
September 2000 - May 2004
Boston University
Field of study
  • Biology

Publications

Publications (15)
Article
A comparative life-cycle assessment (LCA) was performed to evaluate the environmental impacts of an osmotic heat engine (OHE) and an organic Rankine cycle (ORC) for electrical energy generation from low-grade heat. The OHE is a novel membrane-based process that couples pressure retarded osmosis (an energy generating process) and membrane distillati...
Article
Full-text available
Nutrients and water found in domestic treated wastewater are valuable and can be reutilized in urban agriculture as a potential strategy to provide communities with access to fresh produce. In this paper, this proposition is examined by conducting a field study in the rapidly developing city of Hyderabad, India. Urban agriculture trade-offs in wate...
Article
Osmotic power harnesses the energy of mixing between high salinity and low salinity streams to generate mechanical energy. The closed-loop osmotic heat engine (OHE) is a low-grade heat powered, membrane-based energy system that couples membrane distillation (MD), a thermally driven membrane process, with pressure retarded osmosis (PRO), an osmotica...
Article
Full-text available
A life cycle assessment tool and methodology were used to study two potable reuse treatment schemes: a full advanced treatment (FAT) approach and a hybrid ultrafiltration osmotic membrane bioreactor (UFO-MBR). FAT combines conventional wastewater treatment followed by low-pressure membrane filtration, reverse osmosis (RO), and ultraviolet advanced...
Article
Full-text available
The treatment of oil and gas (O&G) exploration wastewaters by forward osmosis (FO) could make water management in the O&G industry more sustainable. Specifically, recovery of pit water from well drilling operations and hydraulic fracturing could reduce the impacts associated with wastewater transportation, deep well disposal, and fresh water procur...
Article
Full-text available
This paper quantifies life cycle energy use and greenhouse gas (GHG) emissions associated with water resource recovery facilities (WRRFs) in India versus water quality improvements achieved from infrastructure investments. A first such analysis is conducted using operating data for a WRRF, which employs upflow anaerobic sludge blanket (UASB) reacto...
Article
Full-text available
This is a first analysis of end-use energy intensity (EUEI) and greenhouse gas (GHG) emissions in water and wastewater (W/WW) sectors in India, and it examines their contribution to community-wide energy use and GHG emissions in cities in India. EUEI and related GHG emissions for W/WW infrastructures in Indian cities were analyzed and compared with...
Article
Full-text available
The Bcl-2 family is important in modulating sensitivity to anticancer drugs in many cancers, including melanomas. The BH3 mimetic ABT-737 is a potent small molecule inhibitor of the anti-apoptotic proteins Bcl-2/Bcl-X(L)/Bcl-w. In this report, we examined whether ABT-737 is effective in killing melanoma cells in combination with the proteasome inhi...
Article
Full-text available
Hyperthermia has been revived as a promising approach for cancer treatment. To understand the underlying mechanisms of hyperthermic killing of cancer cells, we examined the cytotoxic effects of hyperthermia on various skin cancer cell lines using cell viability, morphological analyses, and caspase activation assays. Hyperthermia induced cytotoxicit...
Article
Prelamin A processing is unique amongst mammalian proteins and results in the production of a farnesylated and carboxymethylated peptide. We examined the effect of pathogenic LMNA mutations on prelamin A processing, and of the covalently modified peptide on cardiac and skeletal myoblast differentiation. Here we report a mutation associated with dil...
Article
The cholesterol-lowering medications, statins, inhibit cellular proliferation and induce apoptosis in an array of cancer cell lines, including melanoma. We investigated the apoptotic mechanism of lovastatin on human melanoma cell lines in vitro. The cytotoxicity of statins on multiple cell lines was examined by Cell Titer 96 Aqueous One solution ce...

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