
Lesley Pocock- BA, BSc
- Managing Director at mediWORLD International
Lesley Pocock
- BA, BSc
- Managing Director at mediWORLD International
About
195
Publications
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Introduction
Skills and Expertise
Current institution
mediWORLD International
Current position
- Managing Director
Publications
Publications (195)
Running title: Acarbose and coronary heart disease Background: Atherosclerosis may be the main cause of aging and death. Methods: All patients with sickle cell diseases (SCD) were included. Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (23.8% vs 6.1%, p<0.001), alcohol (4.9% vs 0...
Running title: Idiopathic thrombocytopenic purpura Background: Atherosclerosis may be the major cause of aging and death, and the role of platelets (PLT) is well-known in the terminal consequences of atherosclerosis. Methods: All patients with sickle cell diseases (SCD) were included. Results: We studied 222 males and 212 females with similar ages...
Running title: Stress of excess fat tissue on kidneys
Background: Atherosclerosis may be the major underlying cause of aging and death.
Methods: All patients with sickle cell diseases (SCD) were included.
Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (23.8% vs 6.1%, p<0.001), alc...
Running title: Stress of excess fat tissue on brain
Background: Atherosclerosis may be the major underlying cause of aging and death.
Methods: All patients with sickle cell diseases (SCD) were included.
Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (23.8% vs 6.1%, p<0.001), alcoh...
Running title: Stress of excess fat tissue on heart
Background: Atherosclerosis and coronary heart disease (CHD) may be the main causes of aging and death in human being.
Methods: All patients with sickle cell diseases (SCD) were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively...
Running title: Stress of excess fat tissue on liver
Background: Hardened red blood cells (RBC)-induced capillary endothelial damage initiating at birth terminates with atherosclerotic end-organ failures in much earlier ages of life in sickle cell diseases (SCD).
Methods: All patients with the SCD were included.
Results: We studied 222 males and 212...
Running title: Excess fat tissue in atherosclerosis
Background: Hardened red blood cells (RBC)-induced capillary endothelial damage initiates at birth, and terminates with atherosclerotic end-organ insufficiencies in early years of life in the sickle cell diseases (SCD).
Methods: All patients with the SCD were studied.
Results: We included 222 male...
Running title: Biological ages of sickle cell patients
Background: Hardened red blood cells (RBC)-induced capillary endothelial damage initiates at birth, and terminates with atherosclerotic end-organ insufficiencies in early years of life in sickle cell diseases (SCD).
Methods: All patients with the SCD were studied.
Results: We included 222 males...
Running title: Leg performance in Buerger's disease
Background: After excess weight, smoking may be the second most common cause of vasculitis all over the world.
Methods: All patients with sickle cell diseases (SCD) were studied.
Results: We included 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (2...
Running title: Chronic inflammations and malignancies
Background: The hardened red blood cells-induced capillary endothelial damage is initiated at birth, and terminate with accelerated atherosclerosis, multiorgan failures, and sudden death even at childhood in sickle cell diseases (SCD).
Methods: All cases with the SCD were included.
Results: We s...
Running title: Low-dose warfarin in Buerger's disease
Background: After excess weight, smoking may be the second most common cause of vasculitis all over the body.
Methods: All patients with sickle cell diseases (SCD) were included.
Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (...
Running title: Aspirin plus warfarin in leg ulcers
Background: The hardened red blood cells-induced capillary endothelial damage initiates at birth, and terminates with leg ulcers-like atherosclerotic endpoints even at childhood in the sickle cell diseases (SCD).
Methods: All cases with the SCD were included.
Results: We studied 222 males and 212 f...
Running title: Exaggerated immune response syndromes
Background: Sickle cell diseases (SCD) are severe inflammatory processes mainly on capillaries as the main distributors of hardened red blood cells (RBC) into the tissues. Moderate and severe coronavirus disease (COVID-19) may also be a genetically determined exaggerated inflammatory process on c...
Running title: Chronic inflammations and malignancies
Background: The hardened red blood cells-induced capillary endothelial damage is initiated at birth, and terminate with accelerated atherosclerosis, multiorgan failures, and sudden death even at childhood in sickle cell diseases (SCD).
Methods: All cases with the SCD were included.
Results: We s...
Running title: Capillaritis and acute painful crises
Background: The hardened red blood cells (RBC)-induced capillary endothelial damage, inflammation, edema, and fibrosis are initiated at birth, and terminate with disseminated tissue hypoxia, acute painful crises, multiorgan failures, and sudden death even at childhood in the sickle cell diseases...
Running title: Terminal endpoints of atherosclerosis
Background: Sickle cell diseases (SCD) are severe inflammatory processes in the vasculature mainly on capillary endothelium since they are the main distributors of hardened red blood cells into the tissues. On the other hand, aging and male gender alone may be the most significant underlying risk...
Running title: Severity of diseases restricts smoking
Background: The hardened red blood cells-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood in sickle cell diseases (SCDs).
Methods: All patients were studied.
Results: The study included 334 cases (164 females). There were 27 patie...
Running title: Exaggerated immune response syndromes
Background: Sickle cell diseases (SCD) are severe inflammatory processes on vascular endothelium, particularly at the capillaries since the capillary system is the main distributor of hardened red blood cells into the tissues. Similarly, coronavirus disease (COVID-19) may also be a genetically de...
Running title: Thalassemias in sickle cell diseases
Background: The hardened red blood cells-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood in sickle cell diseases (SCDs).
Methods: All patients with the SCDs were studied.
Results: The study included 334 cases (164 females). There w...
Running title: Atherosclerotic background of cirrhosis
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside ci...
Running title: Chronic obstructive pulmonary disease
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients with the SCDs were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively...
Background: There may be significant relationships between fasting plasma glucose (FPG) and severity of inflammations. Method: All cases with the digital clubbing were included. Results: The study included 104 cases with clubbing detected among 2.428 cases (1.044 males). So clubbing was higher in males (8.1% versus 1.3%, p<0.001). Mean age of clubb...
Running title: Atherosclerosis in teeth losses
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside disseminat...
Running title: Atherosclerotic background of clubbing
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside dig...
Running title: Atherosclerotic background of clubbing
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside dig...
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries. Methods: All patients were included. Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside chronic obstructive pulmonary disease (COPD) (25.2% vs 7....
Running title: Tonsillar hypertrophy in sickle cell
Background: The hardened red blood cells-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood in sickle cell diseases (SCDs).
Methods: All patients with the SCDs were taken into the study.
Results: The study included 334 cases (164 fema...
Running title: Arterial endothelial edema in leg ulcers
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at capillaries.
Methods: All patients were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside leg u...
Background: The hardened red blood cells (RBCs)-induced capillary endothelial damage initiates at birth in sickle cell diseases. Methods: Patients with RBCs transfusions of less than 50 units in their lives were put into the first and 50 units or higher were put into the second groups. Results: There were 224 and 92 patients in the first and second...
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at capillaries. Methods: All patients were included. Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside leg ulcers (19.8% vs 7.0%, p<0.001), smoking (23.8% vs 6.1%,...
Running title: Chronic obstructive pulmonary disease
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients with the SCDs were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively...
Running title: Exaggerated capillary endothelial edema
Background: Sickle cell diseases (SCDs) are inborn and severe inflammatory processes on vascular endothelium, particularly at the capillaries which are the actual distributors of the sickled or just hardened red blood cells (RBCs) into the tissues.
Methods: All patients of the SCDs were include...
Running title: Red cell support in sickle cell diseases
Background: Hardened red blood cells (RBCs)-induced capillary endothelial damage initiates at birth in sickle cell diseases.
Methods: Patients with red blood cells (RBCs) transfusions of less than 50 units in their lives were put into the first and 50 units or higher were put into the second g...
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries. Methods: All patients were included. Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside stroke (12.1% vs 7.5%, p<0.05), smoking (23.8% vs 6.1%, p...
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries. Methods: All patients were included. Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively). Beside chronic renal disease (CRD) (9.9% vs 6.1%, p<0.05), smoki...
Running title: Male gender in sickle cell diseases
Background: Sickle cell diseases are inborn and destructive processes on vascular endothelium, particularly at the capillaries.
Methods: All patients were included.
Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (23.8% vs 6.1%, p<...
Running title: Fasting plasma glucose in inflammations
Background: There may be significant relationships between fasting plasma glucose (FPG) and severity of inflammations.
Method: All cases with the digital clubbing were included.
Results: The study included 104 cases with clubbing detected among 2.428 cases (1.044 males). So clubbing was higher...
Running title: Autosplenectomy in sickle cell diseases
Background: Sickle cell diseases (SCDs) are inborn and destructive processes on vascular endothelium, particularly at the capillaries.
Methods: All patients with the SCDs were included.
Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). A...
Running title: Low-dose warfarin in sickle cell
Background: Sickle cell diseases (SCDs) are inborn and destructive processes on vascular endothelium, particularly at the capillaries.
Methods: All patients with the SCDs were included.
Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Dissemin...
Running title: Corticosteroids in sickle cell diseases
Background: Sickle cell diseases (SCD) are severe inflammatory processes on vascular endothelium, particularly at the capillary level since the capillary system is the main distributor of hardened red blood cells (RBC) into the tissues.
Methods: All patients with the SCD were included.
Results:...
Background: Sickle cell diseases (SCDs) are inborn and destructive processes on vascular endothelium, particularly at the capillaries.
Methods: Patients with red blood cells (RBCs) transfusions of less than 50 units in their lives were put into the first and 50 units or higher were put into the second groups.
Results: There were 224 patients in the...
Running title: Fasting plasma glucose in inflammations
Background: There may be significant relationships between fasting plasma glucose (FPG) and severity of inflammations.
Method: All cases with the digital clubbing were included.
Results: The study included 104 cases with clubbing detected among 2.428 cases (1.044 males). So clubbing was higher...
Running title: Exaggerated capillary endothelial edema
Background: Sickle cell diseases (SCDs) are inborn and severe inflammatory processes on vascular endothelium, particularly at the capillaries which are the actual distributors of the sickled or just hardened red blood cells (RBCs) into the tissues.
Methods: All patients of the SCDs were include...
Running title: Capillary edema in heart and brain
Background: Sickle cell diseases (SCDs) are inborn and severe destructive processes on vascular endothelium, particularly at the capillaries which are the actual distributors of the sickled or just hardened red blood cells (RBCs) into the tissues.
Methods: All patients with the SCDs were included.
R...
Running title: Corticosteroids in sickle cell diseases
Background: Sickle cell diseases (SCD) are severe inflammatory processes on vascular endothelium, particularly at the capillary level since the capillary system is the main distributor of hardened red blood cells (RBC) into the tissues.
Methods: All patients with the SCD were included.
Results:...
Running title: Depression causes inflammations in body
Background: We tried to understand whether or not there are some relationships between irritable bowel syndrome (IBS), chronic gastritis (CG), depression, and various inflammatory processes in the body.
Method: Consecutive patients with IBS and age and sex-matched control cases were included.
R...
Running title: Acute painful crises and sudden deaths
Background: Sickle cell diseases (SCDs) are severe inflammatory processes on vascular endothelium, especially at the capillary level because the capillary system is the actual distributor of hardened red blood cells (RBCs) into the tissues.
Methods: All cases with the SCDs were included.
Results...
Running title: Diabetes mellitus in digital clubbing
Background: There may be some significant relationships between digital clubbing, fasting plasma glucose (FPG), and diabetes mellitus (DM).
Method: All cases with the digital clubbing were included.
Results: The study included 104 patients (85 males) with the digital clubbing detected among 2.428...
Background: There may be a significant relationship between smoking and fasting plasma glucose (FPG) in the human body. Method: Consecutive daily smokers at least for a period of six months and age and sex-matched non-smokers were included into the study. Cases with regular alcohol consumption (one drink a day) and patients with inflammatory, infec...
Running title: Lifelong aspirin in sickle cell diseases
Background: Sickle cell diseases (SCDs) are severe inflammatory processes on vascular endothelium, particularly at the capillary level since the capillary system is the main distributor of hardened red blood cells (RBCs) into the tissues.
Methods: All patients with the SCDs were included.
Resu...
Running title: Smoking and fasting plasma glucose
Background: There may be a significant relationship between smoking and fasting plasma glucose (FPG) in the human body.
Method: Consecutive daily smokers at least for a period of six months and age and sex-matched non-smokers were included into the study. Cases with regular alcohol consumption (one...
Running title: Sickle cell and metabolic syndrome
Background: Sickle cell diseases (SCDs) are severe inflammatory processes on vascular endothelium, particularly at the capillary level since the capillary system is the main distributor of hardened red blood cells (RBCs) into the tissues.
Methods: All patients with the SCDs were included.
Results: T...
Running title: Depression causes inflammations in body
Background: We tried to understand whether or not there are some relationships between irritable bowel syndrome (IBS), chronic gastritis (CG), depression, and various inflammatory processes in the body.
Method: Consecutive patients with IBS and age and sex-matched control cases were included.
R...
Running title: Severity of diseases restricts smoking
Background: The hardened red blood cells-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood in sickle cell diseases (SCDs).
Methods: All patients were studied.
Results: The study included 334 cases (164 females). There were 27 patie...
Running title: Fasting plasma glucose
Background: Smoking may cause a low-grade inflammation on vascular endothelium terminating with an accelerated atherosclerosis-induced end-organ insufficiencies. Plasma triglycerides may be positive acute phase reactants (APRs) whereas fasting plasma glucose (FPG) negative APR indicating the inflammatory effect...
Running title: Smoking and body weight
Background: We tried to understand whether or not there is a long term effect of smoking on the body weight.
Method: Consecutive daily smokers at least with a history of one pack-year and age and sex-matched non-smokers were studied.
Results: The study included 247 smokers (173 males) and 167 non-smokers (112...
Running title: Smoking and lipoproteins in the plasma
Background: There may be some significant relationships between smoking and triglycerides and low density lipoproteins (LDL) in the plasma.
Methods: Consecutive daily smokers at least for a period of six months and age and sex-matched non-smokers were included into the study. Cases with regular...
Running title: Smoking and diabetes mellitus Background: We tried to understand whether or not there is a relationship between smoking and diabetes mellitus (DM). Methods: Current regular smokers for the last six months and age and sex-matched non-smokers were included. Patients with current alcohol consumption (one drink a day) and patients with m...
Running title: Smoking may not prevent excess weight
Background: We tried to understand whether or not there is a long term effect of smoking on prevention of overweight or obesity.
Method: Patients between the ages of 35 and 70 years were studied to be able to see the long term effects of smoking on prevention of overweight and obesity, and to avo...
Running title: Chronic obstructive pulmonary disease
Background: Sickle cell diseases (SCDs) are inborn and catastrophic processes on vascular endothelium, particularly at the capillaries.
Methods: All patients with the SCDs were included.
Results: We studied 222 males and 212 females with similar mean ages (30.8 vs 30.3 years, p>0.05, respectively...
Running title: Smoking-induced moderate inflammation Background: We tried to understand severity of smoking-induced inflammation on vascular endothelium in the process of metabolic syndrome. Methods: Current daily smokers at least for the last six months and age and sex-matched non-smokers were included into the study. Patients with current alcohol...
Running title: Smoking and fasting plasma glucose
Background: We tried to understand whether or not there is a significant relationship between smoking and fasting plasma glucose (FPG).
Methods: Current daily smokers at least for the last six months and age and sex-matched non-smokers were included into the study. Patients with current alcohol cons...
Running title: Irritable gastrointestinal syndrome
Background: Recurrent upper abdominal discomfort may be the cause of nearly half of the applications to the Internal Medicine Clinics, and irritable bowel syndrome (IBS) and chronic gastritis (CG) may be the most commonly diagnosed disorders in such cases.
Method: Consecutive patients with the IBS...
Background: Recurrent upper abdominal discomfort may be the cause of nearly half of the applications to the Internal Medicine Clinics, and irritable bowel syndrome (IBS) and chronic gastritis (CG) may be the most commonly diagnosed disorders in such cases. Method: Consecutive patients with the IBS and age and sex-matched controls were included. Res...
Running title: Smoking and high density lipoproteins Background: We tried to understand whether or not there is a relationship between smoking and high density lipoproteins (HDL) in the plasma. Methods: Current daily smokers at least for the last six months and age and sex-matched non-smokers were included into the study. Patients with current alco...
Running title: Smoking-induced inflammation in the body Background: There may be some positive and negative acute phase reactants (APR) indicating the possible inflammatory effects of smoking on vascular endothelium all over the body. Method: Consecutive daily smokers at least for a period of six months and age and sex-matched non-smokers were take...
Title: Nurses’ Perception of Organizational Support during COVID-19
Pa
Background: Nursing as a profession has been consistently challenging. As a result of the
unstable conditions and continuous unpredictable changes in work environment due to the COVID19 pandemic, nurses are experiencing twice the pressure than nurses who are recruited in normal...
Running title: Smoking may not increase blood pressure Background: We tried to understand whether or not there are some effects of smoking on systolic and diastolic blood pressures (BP). Method: Consecutive daily smokers at least with six pack months and age and sex-matched non-smokers were taken into the study. Cases with regular alcohol consumpti...
Running title: Acute phase reactants in smokers Background: We tried to understand whether or not there are some positive and negative acute phase reactants (APR) indicating the possible inflammatory effects of smoking on vascular endothelium. Method: Consecutive daily smokers at least with a history of one pack-year and age and sex-matched non-smo...
Running title: Inflammation in irritable bowel syndrome Background: Irritable bowel syndrome (IBS) is a common cause of recurrent complaints about gastrointestinal and genitourinary tracts in adults. Method: Consecutive patients with IBS and age and sex-matched controls were studied. IBS was diagnosed according to Rome II criteria in the absence of...
Running title: Acute chest syndrome
Background: Sickle cell diseases (SCD) are severe inflammatory processes on vascular endothelium, particularly at the capillary level since the capillary system is the main distributor of hardened red blood cells (RBC) into tissues.
Methods: All patients with the SCD were included.
Results: The study included 222...
Running title: Irritable bowel syndrome Background: Irritable bowel syndrome (IBS) is one of the frequent causes of recurrent upper abdominal discomfort in adults. Method: Consecutive patients with the IBS and age and sex-matched control cases were studied. IBS was diagnosed according to Rome II criteria in the absence of red flag symptoms includin...
Running title: Pulmonary hypertension
Background: Pulmonary hypertension (PHT) is a common consequence of chronic obstructive pulmonary disease (COPD).
Methods: All patients with sickle cell diseases (SCD) were included.
Results: The study included 434 patients (212 females) with similar mean ages in males and females (30.8 versus 30.3 years, p>0.0...
Running title: Acute phase reactants
Background: We tried to understand some positive and negative acute phase reactants (APR) in sickle cell diseases (SCD).
Methods: Consecutive patients with the SCD and controls were studied.
Results: The study included 193 patients (98 females) and 132 controls (67 females). Although the body weight and body mas...
Running title: Obesity and cirrhosis Background: There may be some significant relationships between the umbilical hernia, obesity, and cirrhosis during the process of metabolic syndrome in adults. Method: Consecutive patients with an umbilical hernia and/or a surgical repair history of the umbilical hernia were included. Results: There are 46 pati...
Running title: Umbilical hernia and metabolic syndrome Background: There may be some significant associations between the umbilical hernia and terminal endpoints of the metabolic syndrome in adults. Method: Consecutive patients with an umbilical hernia and/or a surgical repair history of the umbilical hernia were included into the study. Results: T...
Running title: Familial Mediterranean fever
Background: We tried to understand whether or not there is a persistent inflammatory process in Familial Mediterranean fever (FMF).
Methods: Consecutive patients with the FMF and controls were studied.
Results: The study included 39 patients with the FMF (18 females) and 39 controls. Mean age of the FMF p...
Running title: Hepatitis C virus in sickle cell
Background: We tried to understand whether or not there is a disappearance of hepatitis C virus antibodies (anti-HCV) with hydroxyurea therapy in patients with sickle cell diseases (SCD).
Methods: All patients with the SCD were included, and hydroxyurea therapy was initiated for all of them.
Results:...
Running title: Triglycerides and fasting plasma glucose Background: Irritable bowel syndrome (IBS) may be found among the most common causes of recurrent upper abdominal discomfort in the general population, nowadays. Method: Consecutive patients with IBS and age and sex-matched control cases were studied. IBS was diagnosed according to Rome II cri...
Running title: Acute chest syndrome and atherosclerosis
Background: We tried to understand whether or not there is a significant relationship between acute chest syndrome (ACS) and atherosclerosis in sickle cell diseases (SCD).
Methods: All patients with the SCD were included.
Results: The study included 434 patients (222 males) with similar mean a...
Running title: Autosplenectomy and atherosclerosis
Background: We tried to understand whether or not there is a significant relationship between autosplenectomy and atherosclerosis in sickle cell diseases (SCD).
Methods: All patients with the SCD were included.
Results: The study included 434 patients (222 males and 212 females) with similar mean a...
Running title: Avascular necrosis and atherosclerosis Background: We tried to understand whether or not there is a significant association between avascular necrosis (AVN) and atherosclerosis in sickle cell diseases (SCD). Methods: All patients with the SCD were included. Results: The study included 434 patients (212 females) with similar mean ages...
Background: We tried to understand the presence of any atherosclerotic background of cirrhosis in patients with sickle cell diseases (SCDs). Methods: The study was performed in the Hematology Service of the Mustafa Kemal University on SCDs patients between March 2007 and June 2012. Results: The study included 256 patients with SCDs (127 females). T...
Running title: Sickle cell diseases in male sex Background: We tried to understand prognosis of sickle cell diseases (SCD) in both genders. Methods: All cases with the SCD in the absence of smoking and alcohol were included. Results: The study included 368 patients (168 males and 200 females). Mean age (29.4 versus 30.2 years), associated thalassem...
Running title: Chronic obstructive pulmonary disease Background: We tried to understand prevalence of chronic obstructive pulmonary disease (COPD) in both genders in sickle cell diseases (SCD). Methods: All cases with the SCD in the absence of smoking and alcohol were included. Results: The study included 368 patients (168 males). Mean ages were si...
Running title: Mission of cholesterol and triglycerides Background: We tried to understand some undetermined missions of cholesterol and triglycerides (TG) in the plasma in patients with the sickle cell diseases (SCD). Methods: All patients with the SCD and age and gender-matched control cases were included into the study. Results: We studied 363 p...
Running title: Body mass index and plasma cholesterol Background: We tried to understand possible effects of sickle cell diseases (SCD) on metabolic parameters including cholesterol values in the plasma. Methods: All patients with the SCD and age and gender-matched control cases were included into the study. Results: We studied 363 patients with th...
Running title: Body mass index and blood pressure Background: We tried to understand possible effects of sickle cell diseases (SCD) on metabolic parameters including systolic and diastolic blood pressure (BP) in the body. Methods: All patients with the SCD and age and gender-matched control cases were included into the study. Results: We studied 36...
Background: We tried to understand whether or not there is a significant relationship between autosplenectomy and atherosclerosis in sickle cell diseases (SCD). Methods: All patients with the SCD were included. Results: The study included 434 patients (222 males and 212 females) with similar mean ages in male and female genders (30.8 versus 30.3 ye...
Running title: Triglycerides and acute phase reactants Background: Sickle cell diseases (SCD) are chronic inflammatory process on vascular endothelium terminating with atherosclerosis induced end-organ failures in early decades of life. Methods: Consecutive patients with the SCD and controls were studied. Results: The study included 363 patients wi...
Running title: Sickle cell diseases and height Background: We tried to understand possible effects of sickle cell diseases (SCD) on physical and metabolic parameters. Methods: Consecutive patients with the SCD and age and gender-matched controls were studied. Results: The study included 363 patients with the SCD (169 females) and 255 control cases...
Running title: High and low density lipoproteins Background: We tried to understand whether or not high density lipoproteins (HDL) and low density lipoproteins (LDL) may be negative acute phase proteins (APP) of the metabolic syndrome. Methods: Patients with plasma HDL values lower than 40 mg/dL were collected into the first group, and then age and...
Running title: Safer values of low density lipoproteins
Background: We tried to understand the safer values of low density lipoproteins (LDL) in the plasma.
Methods: Patients with plasma LDL values lower than 80 mg/dL were collected into the first, lower than 100 mg/dL into the second, lower than 130 mg/dL into the third, lower than 150 mg/dL into...
Running title: Body weight and blood pressure
Background: Body weight may have some effects on systolic and diastolic blood pressures (BP) in the body.
Methods: The study was performed in the Hematology and Internal Medicine Polyclinics on patients with sickle cell diseases (SCD) and routine check up cases.
Results: The study included 122 patients...
Running title: Plasma bilirubin in sickle cell diseases
Background: Total bilirubin value of the plasma may have prognostic significance in sickle cell diseases (SCD).
Methods: All patients with the SCD were included between March 2007 and June 2016.
Results: We studied 253 patients (128 females) with a plasma bilirubin value of lower than 5.0 mg/d...
Results: The study included 441 patients (215 females). There were 31 death cases during the ten-year follow up period (14 females with a mean age of 33.3 (19-47) and 17 males with a mean age of 30.2 (19-50) years, p>0.05). Although the mean age of death cases was higher (31.6 versus 30.7 years), the difference was nonsignificant probably due to th...