Lesley J Drake

Lesley J Drake
Imperial College London | Imperial · Department of Infectious Disease Epidemiology

PhD

About

100
Publications
69,192
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
2,949
Citations
Citations since 2017
29 Research Items
1543 Citations
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
2017201820192020202120222023050100150200250
Introduction
Skills and Expertise

Publications

Publications (100)
Article
Full-text available
Global access to deworming treatment is one of the public health success stories of low-income countries in the twenty-first century. Parasitic worm infections are among the most ubiquitous chronic infections of humans, and early success with mass treatment programmes for these infections was the key catalyst for the neglected tropical disease (NTD...
Article
Full-text available
Background Few studies on school eye health programmes have shown they were cost-effective. We compared the performance (Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM)) between an integrated model (IM) and a vertical model (VM) of school eye health delivery in Zanzibar. Methods The set of RE-AIM performance indicators of t...
Preprint
Full-text available
Purpose: To scope the potential for eye health programme to be integrated into Zanzibar School Health programme, through the lenses of stakeholders Methods: Embedded into an operational research project integrating eye and School health, we elicited responses from 83 participants, purposefully selected from the Ministry of Health (n=7), Ministry of...
Article
Full-text available
Objective To review and compare the cost-effectiveness of the integrated model (IM) and vertical model (VM) of school eye health programme in Zanzibar. Methods and analysis This 6-month implementation research was conducted in four districts in Zanzibar. Nine and ten schools were recruited into the IM and VM, respectively. In the VM, teachers cond...
Article
Full-text available
Introduction: Globally, there are 370 million children receiving school meals every day. Coverage is least in low-income countries, where the need is greatest and where program costs are viewed as high in comparison with the benefits to public health alone. Here we explore the policy implications of including the returns of school feeding to other...
Article
Full-text available
The creation of Human Capital is dependent upon good health and education throughout the first 8,000 days of life, but there is currently under-investment in health and nutrition after the first 1,000 days. Working with governments and partners, the UN World Food Program is leading a global scale up of investment in school health, and has undertake...
Article
Healthy students learn better, yet most current investments in schoolchildren focus on education and learning while largely neglecting the health of the learner. Some school-based interventions, such as school feeding and deworming, are already successfully targeted at this age-group, but the efficiency and cost-effectiveness of such programs could...
Article
Full-text available
Background: An accurate understanding of the geographical distributions of both soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale) and schistosomes (SCH; Schistosoma mansoni and S. haematobium) is pivotal to be able to effectively design and implement mass dr...
Preprint
Objective: To review and compare the cost effectiveness of the integrated model (IM) and vertical model (VM) of school eye health programme in Zanzibar. Methods and Analysis: This 6-month implementation research was conducted in four districts in Zanzibar. Nine and ten schools were recruited into the IM and VM respectively. In the VM, teachers cond...
Chapter
Full-text available
The United Nations Standing Committee on Nutrition (UNSCN) is a dedicated platform where UN agencies can have an open, substantive and constructive dialogue on nutrition strategies and initiatives. It is also a place where UN agencies can design joint global approaches, and align their positions and actions when addressing the multi-faceted and evo...
Preprint
Full-text available
Background: The geographical distributions of both soil-transmitted helminths (STHs; Ascarislumbricoides, Trichuristrichiura, and the hookworms (Necatoramericanus and Ancylostomaduodenale) and schistosomes (SCH; Schistosomamansoni and S. haematobium) are pivotal to be able to effectively design and implement mass drug administration (MDA) programs....
Preprint
Full-text available
Background : An accurate understanding of the geographical distributions of both soil-transmitted helminths (STHs; Ascaris lumbricoides , Trichuris trichiura , and the hookworms ( Necator americanus and Ancylostoma duodenale ) and schistosomes (SCH; Schistosoma mansoni and S. haematobium ) is pivotal to be able to effectively design and implement m...
Preprint
Full-text available
Background: An accurate understanding of the geographical distributions of both soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and the hookworms (Necator americanus and Ancylostoma duodenale) and schistosomes (SCH; Schistosoma mansoni and S. haematobium) is pivotal to be able to effectively design and implement mass dr...
Preprint
Full-text available
Background: An accurate understanding of the geographical distributions of both soil-transmitted helminths (STHs; Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale) and schistosomes (SCH; Schistosoma mansoni and S. haematobium) is pivotal to be able to effectively design and implement mass dru...
Article
Full-text available
Background: Attention to nutrition during all phases of child and adolescent development is necessary to ensure healthy physical growth and to protect investments made earlier in life. Leveraging school meals programs as platforms to scale-up nutrition interventions is relevant as programs function in nearly every country in the world. Objective:...
Article
Full-text available
School health and nutrition (SHN) programmes are recognized as a significant contributor to both health and education sector goals. The school system offers an ideal platform from which to deliver basic health interventions that target the most common health conditions affecting school-age children (SAC) in low-income countries, leading to improved...
Technical Report
Full-text available
The HUNGer consortium is comprised of a multi-disciplinary, multi-national consortium of world leading researchers, with expertise in physiology and nutrition, through to clinical research, public health and agriculture in LMIC settings. The HUNGer consortium was awarded the MRC Confidence in Global Nutrition and Health award in 2018. The HUNGer c...
Book
Full-text available
This Resource framework is intended as a guidance tool for stakeholders involved in programme design, implementation and monitoring of Home-Grown School Feeding Programmes and the related policy and institutional environment, including, inter alia: governments and development partners providing technical and financial assistance, as well as civil s...
Article
The realisation of human potential for development requires age-specific investment throughout the 8000 days of childhood and adolescence. Focus on the first 1000 days is an essential but insufficient investment. Intervention is also required in three later phases: the middle childhood growth and consolidation phase (5-9 years), when infection and...
Article
Full-text available
Background Inadequate nutrition; neglected topical diseases; and insufficient water, sanitation, and hygiene (WASH) are interrelated problems in schools in low-income countries, but are not routinely tackled together. A recent three-year longitudinal study investigated integrated school health and nutrition approaches in 30 government primary schoo...
Data
School details, including prevalences and mean intensities of S. mansoni and the STHs. (DOCX)
Article
Full-text available
Study objectives To document the progression of school health and nutrition and its integration within the education sector in sub-Saharan Africa between 2000 and 2015. Background School health and nutrition programs have contributed to “Education for All” objectives by helping ensure that children benefit from quality education and reach their ed...
Article
Full-text available
Background: Interventions that enhance linkages between healthy diets and local agriculture can promote sustainable food systems. Home-grown school feeding programs present a promising entry point for such interventions, through the delivery of nutritious menus and meals. Objective: To describe the adaptation of the School Meals Planner Package...
Article
Full-text available
Background It is thought that improving water, sanitation, and hygiene (WASH) might reduce the transmission of schistosomes and soil-transmitted helminths, owing to their life cycles. However, few large-scale studies have yet assessed the real extent of associations between WASH and these parasites. Methodology/Principal Findings In the 2013–2014...
Data
School water and sanitation combined scores against their arithmetic mean S. mansoni infection intensities. Kendall’s τb statistics, the equation of the least-squares line of best fit, and the number of included schools, are presented in the upper-right corner. (JPG)
Data
Comparisons of WASH scores between schools with zero and non-zero prevalences of each parasite. (XLSX)
Data
Flow diagram showing the manipulation of the various datasets. (JPG)
Data
Arithmetic mean intensity of infection against arithmetic mean of the age of those tested for A. S. mansoni, B. A. lumbricoides, C. T. trichiura, and D. hookworm, in schools with non-zero prevalences of each parasite. The lines of best fit are shown in blue. Their equations, the coefficients of determination (R2) and the number of schools (n) are p...
Data
School sanitation and hygiene combined scores against their arithmetic mean infection intensities for A. A. lumbricoides, B. T. trichiura, and C. hookworm. The Kendall’s τb statistics, least-squares best fit line equation, and sample size are presented in the upper-right corner of each graph. (JPG)
Data
Comparisons of infection intensities and WASH scores between the schools included in the analysis, and those that were excluded since they could not be matched to the other database. (XLSX)
Article
Full-text available
Background: 'Home-grown' school feeding programmes are complex interventions with the potential to link the increased demand for school feeding goods and services to community-based stakeholders, including smallholder farmers and women's groups. There is limited rigorous evidence, however, that this is the case in practice. This evaluation will ex...
Article
Full-text available
Globally, more than 600 million school-age children are at risk of infection with soil-transmitted helminths (STH) and require treatment. These infected children frequently carry the largest burden of disease in a community and are at greater risk of malnutrition and anaemia , with detrimental effects on educational access and learning as well as m...
Article
Full-text available
Abstract Background Soil-transmitted helminths (STHs) infect over a billion individuals worldwide. In India, 241 million children are estimated to need deworming to avert the negative consequences STH infections can have on child health and development. In February-April 2011, 17 million children in Bihar State were dewormed during a government-l...
Article
Full-text available
This cross-sectional study examines the status and the determinants of primary education in food insecure areas of Mali. Net and gross enrolment ratios in primary school were between 0.3 and 0.4 for both girls and boys and well below national levels, highlighting a critical gap in terms of access to primary education. Schooling was found to respond...
Article
Full-text available
To assess the impact of deworming and iron supplementation on the cognitive abilities and educational achievement of school-age children in Sri Lanka. Prospective, placebo-controlled randomised study. The treatment group received deworming and weekly iron supplementation for 6 months; the control group received placebo for both the anthelmintic and...
Data
objective To assess the impact of deworming and iron supplementation on the cognitive abilities and educational achievement of school-age children in Sri Lanka. methods Prospective, placebo-controlled randomised study. The treatment group received deworming and weekly iron supplementation for 6 months; the control group received placebo for both th...
Article
Full-text available
Background We set out to estimate, for the three geographical regions with the highest HIV prevalence, (sub-Saharan Africa [SSA], the Caribbean and the Greater Mekong sub-region of East Asia), the human resource and economic impact of HIV on the supply of education from 2008 to 2015, the target date for the achievement of Education For All (EFA), c...
Data
Principal costs entered into the model. (DOC)
Data
Mathematical description of the model. (DOC)
Data
List of countries for which estimations and projections were made, by region. (DOC)
Data
Summary of data used in the model. Data value followed by year in brackets. Where the data are age distributions, just the year is given. Age-gender disaggregated data were entered for HIV prevalence. (DOC)
Article
Full-text available
Objective: An analysis undertaken jointly in 2009 by the UN World Food Programme, The Partnership for Child Development and the World Bank was published as Rethinking School Feeding to provide guidance on how to develop and implement effective school feeding programmes as a productive safety net and as part of the efforts to achieve Education for...
Book
Full-text available
This report, which was prepared with the participation of senior education policy makers and administrators, academics, researchers, employers, education providers, principals, teachers and students, serves several purposes. First, the report contains rigorous technical analyses and provides an understanding of the general education sector based on...
Article
Courage and Hope gives voice to the real life experiences of 12 HIV-positive teachers, five of whom are women, from Burkina Faso, Cameroon, Ghana, Kenya, Mozambique, Rwanda, Senegal, Tanzania (both Mainland and Zanzibar) and Zambia. The teachers recount their experiences of discovering their HIV-positive status and how this has affected them in the...
Data
Full-text available
Alignment of β-tubulin cDNA sequences from 11 nematodes. (1.89 MB PDF)
Article
Full-text available
Background: The soil-transmitted helminths (STH) Ascaris lumbricoides and Trichuris trichiura are gastrointestinal parasites causing many disabilities to humans, particularly children. The benzimidazole (BZ) drugs, albendazole (ALB) and mebendazole (MBZ), are commonly used for mass treatment for STH. Unfortunately, there is concern that increased...
Article
Full-text available
In 2007, the World Health Organization, together with United Nations and international organization as well as experts, met to draw upon existing evidence and practical experience from regions, countries and individual schools in promoting health through schools. The goal of the meeting was to identify current and emerging global factors affecting...
Article
Full-text available
Providing good quality education to all children in the poorest countries of the world is not a simple task. However, improving children's health and nutrition is one simple step that can be taken towards achieving this goal. Health and nutrition programmes offer substantial benefits to children's education, helping them to attend school and learn...
Chapter
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Chapter
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Chapter
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Chapter
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Chapter
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Chapter
Full-text available
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Chapter
This book contains 7 chapters. The following topics are discussed: case for school health and nutrition; challenges for child health and nutrition (infectious diseases and nutritional deficiencies); health, nutrition and access to education; long-term effects of preschool health and nutrition on educational achievement; health, nutrition and educat...
Data
Translation of the Abstract into French by Giorgio Sirugo and Jérôme Feldman (21 KB DOC)
Data
Translation of the Abstract into Spanish by Conchi Vera-Valderrama and Miguel Vargas-Reus (24 KB DOC)
Data
Factor Loadings for the Six Cognitive Tests (27 KB DOC)
Data
Estimates of Prophylaxis Effect on Educational Attainment Using Ordinal Logistic Regression (37 KB DOC)
Article
Full-text available
We investigated the long-term impact of early childhood malaria prophylaxis on cognitive and educational outcomes. This was a household-based cluster-controlled intervention trial. The study was conducted in 15 villages situated between 32 km to the east and 22 km to the west of the town of Farafenni, the Gambia, on the north bank of the River Gamb...
Chapter
To investigate the relationships between helminth infections and iron status among school-aged children, 1,115 Tanzanian children in grades 2 through 5 were randomly assigned to treatment or control groups. The children in the treatment group were screened for infection with Schistosoma haematobium and hookworm at baseline, 3 months, and 15 months;...