Leonides Canuet Delis

• Senior Researcher at University of La Laguna

Tetris has recently expanded its place of activity not only to an entertainment but aiso to clinical applications such as cognitive training and prevention of trauma flashback． However， to our knowledge， no studies focused on cortical activation patterns themselves when playing Tetris in anatural form． This study aimed to investigate activation pat...

Objectives: eLORETA (exact low-resolution brain electromagnetic tomography) is a technique created by Pascual-Marqui et al. [Int J Psychophysiol. 1994 Oct; 18(1): 49-65] for the 3-dimensional representation of current source density in the brain by electroencephalography (EEG) data. Kurtosis analysis allows for the identification of spiky activity...

Humans perform remarkably well in many cognitive tasks including pattern recognition. However, the neuronal mechanisms underlying this process are not well understood. Nevertheless, artificial neural networks, inspired in brain circuits, have been designed and used to tackle spatio-temporal pattern recognition tasks. In this paper we present a mult...

Humans perform remarkably well in many cognitive tasks including pattern recognition. However, the neuronal mechanisms underlying this process are not well understood. Nevertheless, artificial neural networks, inspired in brain circuits, have been designed and used to tackle spatio-temporal pattern recognition tasks. In this paper we present a mult...

We applied rhythmic binaural sound to Parkinson's Disease (PD) patients to investigate its influence on several symptoms of this disease and on Electrophysiology (Electrocardiography and Electroencephalography (EEG)). We conducted a double-blind, randomized controlled study in which rhythmic binaural beats and control were administered over two ran...

This century is about brain. Not surprisingly, two megaprojects, the “Brain Activity Map Project” (USA) and the “Human Brain Project” (EU) with a total budget over a few billions euros, have been initiated across the Atlantic and mobilized many of the best and most renowned neuroscientists. They both aims to answer open questions for Neuroscience,...

Purpose: Juvenile myoclonic epilepsy (JME) is one of the most common generalized idiopathic epilepsies of childhood and adolescence. In some patients with JME, mathematical calculus and praxis may induce myoclonic seizures. Methods: A reflex myoclonic seizure was recorded by simultaneous magnetoencephalography (MEG) and electroencephalography (E...

The purpose of our study was to identify the main factors associated with objective noise-induced hearing loss (NIHL), as indicated by abnormal audiometric testing, in Spanish workers exposed to occupational noise in the construction industry. We carried out a prospective study in Tenerife, Spain, using 150 employees exposed to occupational noise a...

In the last decade important progress has been made with regard to clinical recovery in patients with disabling neurological conditions such as ischemic and hemorrhagic stroke. Until recently, the lack of effective treatment for stroke left patients with impaired cognition and severe physical disability with no hope of clinical recovery. Nowadays,...

Unlabelled: Synaptic dysfunction is a core deficit in Alzheimer's disease, preceding hallmark pathological abnormalities. Resting-state magnetoencephalography (MEG) was used to assess whether functional connectivity patterns, as an index of synaptic dysfunction, are associated with CSF biomarkers [i.e., phospho-tau (p-tau) and amyloid beta (Aβ42)...

Scopolamine administration may be considered as a psychopharmacological model of Alzheimer’s disease (AD). Here, we studied a group of healthy elderly under scopolamine to test whether it elicits similar changes in brain connectivity as those observed in AD, thereby verifying a possible model of AD impairment. We did it by testing healthy elderly s...

Over the past years, several studies on Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) have reported Default Mode Network (DMN) deficits. This network is attracting increasing interest in the AD community, as it seems to play an important role in cognitive functioning and in beta amyloid deposition. Attention has been particularly dra...

Aim: The aim of this study was to investigate whether magnetoencephalographic oscillations underlying working memory dysfunction in the dorsolateral prefrontal cortex (DLPFC) are related to psychopathological disturbance in patients with schizophrenia-like psychosis of epilepsy (SLPE). Methods: Twelve patients with SLPE and 14 non-psychotic epileps...

iNPH (idiopathic normal pressure hydrocephalus) is a syndrome that is characterized by a classic triad of symptoms including dementia, urinary incontinence and gait disturbance. Lumbar tap test (LTT) is most common test to evaluate shunt-responsiveness before neurosurgical operation, as this test involves the withdrawal of CSF by means of lumbar pu...

from migraine and to identify the factors associated with these variables. Patients and methods. A non-experimental study based on observation was conducted with 116 patients diagnosed as having migraine, who were consecutively admitted to the Casualty department at the Institute of Neurology and Neurosurgery. The chief variables used in the study...