Leonida A Gizzi

• Ph.D, Imperial College, London
• Head of Unit at INO - Istituto Nazionale di Ottica - CNR

We present 50-fs, single-shot measurements of the x-ray thermal diffuse scattering (TDS) from copper foils that have been shocked via nanosecond laser ablation up to pressures above ∼ 135 GPa. We hence deduce the x-ray Debye–Waller factor, providing a temperature measurement. The targets were laser-shocked with the DiPOLE 100-X laser at the High En...

Advanced and novel accelerators (ANAs), driven a by laser pulse or a relativistic particle bunch, have made remarkable progress over the last decades. They accelerated electrons by 10GeV in 30cm (laser driven) and by 42GeV in 85cm (particle bunch driven). Rapid progress continues with lasers, plasma sources, computational methods, and more. In this...

Fast electron generation and transport in high-intensity laser–solid interactions induces X-ray emission and drives ion acceleration. Effective production of these sources hinges on an efficient laser absorption into the fast electron population and control of divergence as the beam propagates through the target. Nanowire targets can be employed to...

The use of very high energy electron (VHEE) beams, with energies between 50 and 400 MeV, has drawn considerable interest in radiotherapy due to their deep tissue penetration, sharp beam edges, and low sensitivity to tissue density. VHEE beams can be precisely steered with magnetic components, positioning VHEE therapy as a cost-effective option betw...

We present 50-fs, single-shot measurements of the x-ray thermal diffuse scattering (TDS) from copper foils that have been shocked via nanosecond laser-ablation up to pressures above 135~GPa. We hence deduce the x-ray Debye-Waller (DW) factor, providing a temperature measurement. The targets were laser-shocked with the DiPOLE 100-X laser at the High...

The use of Very High Energy Electron (VHEE) beams, with energies between 50 and 400 MeV, has drawn considerable interest in radiotherapy due to their deep tissue penetration, sharp beam edges, and low sensitivity to tissue density. VHEE beams can be precisely steered with magnetic components, positioning VHEE therapy as a cost-effective option betw...

Particle-induced x-ray emission (PIXE) is a well-established ion-beam analysis technique, enabling quantitative measurement of the elemental composition of a sample surface under an ambient atmosphere with an external beam, which significantly simplifies the measurements, and is strictly necessary for those samples that cannot sustain a vacuum envi...

RF photoguns are the most common electron sources for FELs and Compton facilities. They are key in such accelerator facility and, presently, primarily operated in the S band regime (3 GHz). Such S band RF photoguns typical achieve cathode peak fields of 80-120 MV/m and repetition rates lower than 120 Hz. An innovative C Band (5.712 GHz) RF gun aimi...

X-ray free electron laser (XFEL) sources coupled to high-power laser systems offer an avenue to study the structural dynamics of materials at extreme pressures and temperatures. The recent commissioning of the DiPOLE 100-X laser on the high energy density (HED) instrument at the European XFEL represents the state-of-the-art in combining x-ray diffr...

Major strides have been made in the development of FLASH radiotherapy (FLASH RT) in the last ten years, but there are still many obstacles to overcome for transfer to the clinic to become a reality. Although preclinical and first-in-human clinical evidence suggests that ultra-high dose rates (UHDRs) induce a sparing effect in normal tissue without...

We report on a study of laser plasma instabilities with 527 nm laser pulses in an intensity range of 0.5 × 10 13 − 1.1 × 10 15 W cm − 2 and plasma parameters entering a regime that is relevant for direct drive inertial confinement fusion. Using the kilojoule high repetition rate L4n laser at the Extreme Light Infrastructure—Beamlines, more than 130...

Electron plasma waves can be efficiently excited by a resonant train of ultrashort pulses, spatially separated by a plasma wavelength. Generating a pulse train from a single amplified ultrashort pulse may be challenging when dealing with large beams. Here we discuss a pulse splitting technique using a simple delay mask that can be adapted to large...

Shock Ignition is a two-step scheme to reach Inertial Confinement Fusion, where the precompressed fuel capsule is ignited by a strong shock driven by a laser pulse at an intensity in the order of 1016\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mat...

The next years will see the completion of several new facilities at Istituto Nazionale di Fisica Nucleare – Laboratori Nazionali del Sud (LNS) opening up new possibilities in the fields of nuclear structure, nuclear dynamics, nuclear astrophysics and applications. These include a new line for high-intensity cyclotron beams, a new facility for in-fl...

We present an innovative X-ray spectroscopy system to address the complex study of the X-ray emissions arising from laser–target interactions, where the emissions occur within extremely brief intervals from femtoseconds to nanoseconds. Our system combines a Gas Electron Multiplier (GEM) detector with a silicon-based Timepix3 (TPX3) detector. These...

The recent achievement of fusion ignition with laser-driven technologies at the National Ignition Facility sets a historic accomplishment in fusion energy research. This accomplishment paves the way for using laser inertial fusion as a viable approach for future energy production. Europe has a unique opportunity to empower research in this field in...

We report on the commissioning of a full aperture backscatter diagnostics station for the kilojoule, nanosecond high repetition rate L4n laser operating at a wavelength of 527 nm at the Extreme Light Infrastructure (ELI) - Beamlines, Dolni Brezany, Czech Republic. Light scattered back from laser–plasma interaction into the cone of the final focusin...

In an experiment carried out at the Prague Asterix Laser System at laser intensities relevant to shock ignition conditions (I > 1016 W/cm2), the heating and transport of hot electrons were studied by using several complementary diagnostics, i.e., Kα time-resolved imaging, hard x-ray filtering (a bremsstrahlung cannon), and electron spectroscopy. Ab...

C-band technology is emerging as an exciting innovative approach to the creation of compact new accelerators. Besides the possibility to sustain higher gradients and higher repetition rate operation at normal conducting temperature, it also allows one to increase the machine performance in terms of beam brightness. We propose the design study of a...

Laser plasma instabilities, such as stimulated Raman scattering (SRS) and two-plasmon decay (TPD), are basic phenomena in intense laser science and applications. In direct-drive inertial confinement fusion (ICF) where a fuel capsule is imploded by high-power lasers, SRS and TPD are generally problematic because hot electrons (HEs) generated by SRS...

Shock Ignition is a two-step scheme to reach Inertial Confinement Fusion, where the precompressed fuel capsule is ignited by a strong shock driven by an intense laser pulse at intensity ∼ 10 ¹⁶ W/cm ² . In this report we detail the results of an experiment designed to investigate the origin of hot electrons (HE) in laser-plasma interaction at inten...

On behalf of all at High Power Laser Science and Engineering we would like to congratulate the team at Lawrence Livermore National Laboratory (LLNL) on demonstrating fusion ignition at the National Ignition Facility. This major scientific achievement was realized on the 5 December 2022 at the LLNL and announced at a press briefing on the 13 Decembe...

Laser–plasma interaction and hot electrons have been characterized in detail in laser irradiation conditions relevant for direct-drive inertial confinement fusion. The experiment was carried out at the Gekko XII laser facility in multibeam planar target geometry at an intensity of approximately $3\times {10}^{15}$ W/cm ² . Experimental data suggest...

A model for the calculation of the pump energy coupling to a disk amplifier is presented. The disk is considered to be pumped on its edge by diode bars. A composite geometry, namely a disk with a doped (pump absorbing) inner region surrounded by an undoped region is considered. The model allows the overall pump energy coupling as well as the absorp...

The shock ignition (SI) approach to inertial confinement fusion is a promising scheme for achieving energy production by nuclear fusion. SI relies on using a high intensity laser pulse (≈10 16 W/cm 2 , with a duration of several hundred ps) at the end of the fuel compression stage. However, during laser-plasma interaction (LPI), several parametric...

Laser accelerators promised to deliver high-energy particle beams for biomedical uses, but have struggled to meet constraints on dose control and stability. An experiment now enables translational research with proton beams at ultrahigh dose rate.

In August 2021, at the National Ignition Facility of the Lawrence Livermore National Laboratory in the USA, a 1.35 MJ fusion yield was obtained. It is a demonstration of the validity of the Inertial Confinement Fusion approach to achieve energy-efficient thermonuclear fusion in the laboratory. It is a historical milestone that the scientific commun...

High power lasers have proven being capable to produce high energy gamma rays, charged particles and neutrons to induce all kinds of nuclear reactions. At ELI, the studies with high power lasers will enter for the first time into new domains of power and intensities.

We report on the conceptual design of a 2 μm, broadband laser multipass amplifier system based on Tm-doped gain medium, including an overview of the model established to optimize the performance of a diode edge-pumped high-power solid-state thin-disk configuration.

Purpose Flash radiotherapy (FLASH-RT) is currently being regarded as the next breakthrough in radiation treatment of cancer, delivering ultrahigh radiation doses in a very short time, and sparing normal tissues from detrimental injury. Here we review the current evidence on the preclinical findings as well as the radiobiological mechanisms underlyi...

After the introduction of the ionization-injection scheme in laser wake field acceleration and of related high-quality electron beam generation methods, such as two-color and resonant multi-pulse ionization injection (ReMPI), the theory of thermal emittance has been used to predict the beam normalized emittance obtainable with those schemes. We rec...

We report results and modelling of an experiment performed at the Target Area West Vulcan laser facility, aimed at investigating laser–plasma interaction in conditions that are of interest for the shock ignition scheme in inertial confinement fusion (ICF), that is, laser intensity higher than ${10}^{16}$ $\mathrm{W}/{\mathrm{cm}}^2$ impinging on a...

Fusion energy research is delivering impressive new results emerging from different infrastructures and industrial devices evolving rapidly from ideas to proof-of-principle demonstration and aiming at the conceptual design of reactors for the production of electricity. A major milestone has recently been announced in laser fusion by the Lawrence Li...

After the introduction of the ionization-injection scheme in Laser Wake Field Acceleration and of related high-quality electron beam generation methods as two-color or the Resonant Multi Pulse Ionization injection, the theory of thermal emittance by C. Schroeder et al, has been used to predict the beam normalised emittance obtainable with those sch...

We report results and modelling of an experiment performed at the TAW Vulcan laser facility, aimed at investigating laser-plasma interaction in conditions which are of interest for the Shock Ignition scheme to Inertial Confinement Fusion, i.e. laser intensity higher than 10^16 W/cm2 impinging on a hot (T > 1 keV), inhomogeneous and long scalelength...

Proton laser-plasma-based acceleration has nowadays achieved a substantial maturity allowing to seek for possible practical applications, as for example Particle Induced X-ray Emission with few MeV protons. Here we report about the design, implementation, and characterization of a few MeV laser-plasma-accelerated proton beamline in air using a comp...

The interaction of ultraintense laser pulses with solids is largely affected by the plasma gradient at the vacuum–solid interface, which modifies the absorption and ultimately, controls the energy distribution function of heated electrons. A micrometer scale-length plasma has been predicted to yield a significant enhancement of the energy and weigh...

The coupling of ultra-intense, ultra-short laser pulses with solid targets is heavily dependent on the properties of the vacuum–solid interface and is usually quite low. However, laser absorption can be enhanced via micro or nanopatterning of the target surface. Depending on the laser features and target geometry, conditions can be optimized for th...

The interaction of ultraintense laser pulses with solids is largely affected by the plasma gradient at the vacuum-solid interface, which modifies the absorption and ultimately, controls the energy distribution function of heated electrons. A micrometer scale-length plasma has been predicted to yield a significant enhancement of the energy and weigh...

The interaction of ultraintense laser pulses with solids is largely affected by the plasma gradient at the vacuum-solid interface, which modifies the absorption and ultimately, controls the energy distribution function of heated electrons. A micrometer scale-length plasma has been predicted to yield a significant enhancement of the energy and weigh...

Plasma-based accelerators use the strong electromagnetic fields that can be supported by plasmas to accelerate charged particles to high energies. Accelerating field structures in plasma can be generated by powerful laser pulses or charged particle beams. This research field has recently transitioned from involving a few small-scale efforts to the...

The design, realization and test of a few-MeV proton-laser–based source to be used for PIXE measurements at atmospheric pressure are reported. The system comprises a 14 TW 30 fs laser system, a motorized laser-plasma target holder and a compact magnetic beam line designed using GEANT4 simulation tools. During the experimental tests the transported...

We report on the optimization of a BremsStrahlung Cannon (BSC) design for the investigation of laser-driven fast electron populations in a shock ignition relevant experimental campaign at the Laser Megajoule-PETawatt Aquitaine Laser facility. In this regime with laser intensities of 10¹⁵ W/cm²–10¹⁶ W/cm², fast electrons with energies ≤100 keV are e...

We present the main features of the ultrashort, high-intensity laser installation at the Intense Laser Irradiation Laboratory (ILIL) including laser, beam transport and target area specifications. The laboratory was designed to host laser–target interaction experiments of more than 220 TW peak power, in flexible focusing configurations, with ultrar...

Trains of femtosecond pulses generated by a delay mask are considered for application to laser driven acceleration of particles. Here we show the results of numerical simulations and a preliminary experimental characterization of a two-pulse configuration.

We describe the initial development of an edge-pumped ceramic Tm:Lu2O3 multipass amplifier for ultra-short pulse laser with high-repetition rate, high-peak power and high-average power, with an overview of the laser chain and the amplifiers specifications

This report presents the conceptual design of a new European research infrastructure EuPRAXIA. The concept has been established over the last four years in a unique collaboration of 41 laboratories within a Horizon 2020 design study funded by the European Union. EuPRAXIA is the first European project that develops a dedicated particle accelerator r...

This report presents the conceptual design of a new European research infrastructure EuPRAXIA. The concept has been established over the last four years in a unique collaboration of 41 laboratories within a Horizon 2020 design study funded by the European Union. EuPRAXIA is the first European project that develops a dedicated particle accelerator r...

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Radiotherapy with very high energy electrons has been investigated for a couple of decades as an effective approach to improve dose distribution compared to conventional photon-based radiotherapy, with the recent intriguing potential of high dose-rate irradiation. Its practical application to treatment has been hindered by the lack of hospital-scal...

Laser plasma created by intense light interaction with matter plays an important role in high-energy density fundamental studies and many prospective applications. Terawatt laser-produced plasma related to the low collisional and relativistic domain may form supersonic flows and is prone to the generation of strong spontaneous magnetic fields. The...

In this paper we report the measurement of laser-driven proton acceleration obtained by irradiating nanotube array targets with ultrashort laser pulses at an intensity in excess of 10²⁰ W cm⁻². The energetic spectra of forward accelerated protons show a larger flux and a higher proton cutoff energy if compared to flat foils of comparable thickness....

We show that both the flux and the cutoff energy of protons accelerated by ultraintense lasers can besimultaneously increased when using targets consisting of thin layers of bundled nanochannels. Particle-in-cellsimulations suggest that the propagation of an electromagnetic field in the subwavelength channels occurs viaexcitation of surface plasmon...

We report on recent experimental results on proton acceleration from laser interaction with foil targets at ultra-relativistic intensities. We show a three-fold increase in the proton cut-off energy when a micrometer scale-length pre-plasma is introduced by irradiation with a low energy femtosecond pre-pulse. The foil target is sufficiently thick t...

Particle-In-Cell (PIC) simulation are fundamental to address a detailed study of a Laser Wake Field Acceleration process. Given the ongoing development of cm-scale plasma accelerators, reduced physical models are necessary to face otherwise unfeasible predictive start-to-end simulations. In this context, the equation of a plasma in the cold fluid a...

We describe the latest progress towards the development of a laser-produced proton beam line for Particle Induced X-ray Emission (PIXE) applications. The specific aim of the project is the design, realization and test of a compact laser-based source of a few MeV protons to be used for PIXE measurements at atmospheric pressure.

In the Shock Ignition scheme, the spike pulse intensity is well above the threshold of parametric instabilities, which produce a considerable amount of hot electrons that could be beneficial or detrimental to the ignition. To study their impact, an experiment has been carried out on the LMJ-PETAL facility with a goal to generate a strong shock insi...

Flowing plasma jets are increasingly investigated and used for surface treatments, including biological matter, and as soft ionization sources for mass spectrometry. They have the characteristic capability to transport energy from the plasma excitation region to the flowing afterglow, and therefore to a distant application surface, in a controlled...

From plasma-wakefield acceleration as a physics experiment toward a plasma-based accelerator as a user facility, the beam physics issues remaining to be solved are still numerous. Providing beams with high energy, charge, and quality simultaneously, not only within the plasma but also at the user doorstep itself, is the main concern. Despite its tr...

High-repetition rate target development for proton acceleration by laser-plasma experiments is of great importance for future multidisciplinary applications, as envisioned at the ELIMAIA user beamline. The use of gas-jet based target, capable of high-repetition rate (10Hz and beyond) and typically used to generate under-critical density plasma, can...

Laser wakefield acceleration of GeV electrons is becoming a mature technique, so that a reliable accelerator delivering stable beams to users communities can now be considered. In such a context, two plasma stages, one injector and one booster stage, offer a flexible solution for optimization. For the injector we consider here the resonant multipul...

We present the results of an experiment on laser-driven shock waves performed at the Prague Asterix Laser system (PALS), where the fundamental frequency of the laser (1315 nm) is used to launch a strong shock in planar geometry. The experiment aims to characterize both shock waves and hot electrons generated at intensities of ≃1016 W/cm2. It is sho...

The Horizon 2020 project EuPRAXIA (European Plasma Research Accelerator with eXcellence In Applications) is producing a conceptual design report for a highly compact and cost-effective European facility with multi-GeV electron beams accelerated using plasmas. EuPRAXIA will be set up as a distributed Open Innovation platform with two construction si...

The EuPRAXIA project aims at designing the world's first accelerator based on advanced plasma-wakefield techniques to deliver 5 GeV electron beams that simultaneously have high charge, low emittance and low energy spread, which are required for applications by future user communities. Meeting this challenging objective will only be possible through...

Novel accelerator schemes are rapidly emerging in the wake of laser-plasma acceleration research and involve advanced high-power laser drivers for their operation. Significant progress has been made in laser performance during the past decade, including repetition rate, average and peak power, and footprint, making these systems attractive for many...

The production of high-quality electron bunches in laser wakefield acceleration relies on the possibility of injecting ultra-low emittance bunches in the plasma wave. A new bunch injection scheme (resonant multi-pulse ionization, ReMPI) has been conceived and studied, in which electrons extracted by ionization are trapped by a large-amplitude plasm...

Plasma accelerators present one of the most suitable candidates for the development of more compact particle acceleration technologies, yet they still lag behind radiofrequency (RF)-based devices when it comes to beam quality, control, stability and power efficiency. The Horizon 2020-funded project EuPRAXIA (“European Plasma Research Accelerator wi...

Ultraintense lasers are now established as powerful drivers for high energy particle, plasma based Laser plasma accelerator and unique compact radiation sources. Further developments will require the coalescence of a wide range of fields, from optics and lasers, to plasmas Particle beams particle beams, to deliver the first Laser plasma accelerator...

The purpose of the European project EuPRAXIA is to realize a novel plasma accelerator user facility. The laser driven approach sets requirements for a very high performance level for the laser system: pulse peak power in the petawatt range, pulse repetition rate of several tens of Hz, very high beam quality and overall stability of the system param...

Accurate dynamic three-dimensional (4D) imaging of the heart of small rodents is required for the preclinical study of cardiac biomechanics and their modification under pathological conditions, but technological challenges are met in laboratory practice due to the very small size and high pulse rate of the heart of mice and rats as compared to huma...

The use of a gas cell as a target for laser weakfield acceleration (LWFA) offers the possibility to obtain stable and manageable laser-plasma interaction process, a mandatory condition for practical applications of this emerging technique, especially in multi-stage accelerators. In order to obtain full control of the gas particle number density in...

Implementation of laser-plasma-based acceleration stages in user-oriented facilities requires the definition and deployment of appropriate diagnostic methodologies to monitor and control the acceleration process. An overview is given here of optical diagnostics for density measurement in laser-plasma acceleration stages, with emphasis on well-estab...

Laser–plasma interaction (LPI) at intensities $10^{15}{-}10^{16}~\text{W}\cdot \text{cm}^{-2}$ is dominated by parametric instabilities which can be responsible for a significant amount of non-collisional absorption and generate large fluxes of high-energy nonthermal electrons. Such a regime is of paramount importance for inertial confinement fusio...