Leonardo Seligra Lopes

• MD MSc
• Medical Professional at Faculdade de Medicina do ABC

Background There is still few evidence to support the use of low-intensity extracorporeal shockwave therapy (LiESWT) in rehabilitation of erectile function after radical prostatectomy (RP). Aim The aim of this study is to assess the long-term results of LiWEST as a penile rehabilitation method in patients who underwent RP. Methods This is an asse...

Introduction COVID-19, characterized by the World Health Organization as a pandemic [1], has affected human beings as a whole. Social isolation has led to feelings of fear, anxiety and panic, and can cause even more serious effects such as depression and sexual dysfunction. Over the last year, several studies have been carried out around the world...

Introduction There is still few evidence to support the use of low-intensity extracorporeal shockwave therapy (LiESWT) in the management of erectile dysfunction (ED) after radical prostatectomy (RP). Objective The aim of this study is to assess the long-term results of LiWEST as a penile rehabilitation method in patients who underwent RP. Methods...

Introduction Spinal cord injury (SCI) is a relevant medical and social problem. According to the World Health Organization, the commonly estimated worldwide annual incidence of SCI is 40 to 80 cases per million population. After the SCI experience, many men present with erectile dysfunction (ED). Recently, an implantable neurostimulator (CaverSTIM)...

Objectives To evaluate the impact of COVID-19 pandemics on clinical and surgical practice, educational activities, health and lifestyle behavior of Brazilian urology residents after 1 year of socio-economic restrictions. Materials and Methods An electronic survey was e-mailed to all postgraduate (PG) students registered by the Brazilian Society of...

Introduction: Prostate cancer (PC) is the second most frequent neoplasm in men accounting for 29% of tumor cases, at a rate of 1.4 million new cases and 375,000 deaths globally each year. Although its high prevalence, little is known about its etiology. Sexually transmitted infections (STIs) are one of the factors under discussion for a possible ri...

Purpose Statins are one of the most prescribed classes of drugs worldwide to treat hypercholesterolemia and dyslipidemia. By lowering the level of cholesterol, the use of statin could cause a reduction in testosterone levels. The objective was to evaluate whether the continued use of statins in patients with hypercholesterolemia causes a deficiency...

Introduction: Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) is the first validated questionnaire to specifically evaluate the satisfaction of patients undergoing penile prosthesis implantation. Our primary aim was to conduct a systematic review and pooled analysis of articles reporting QoLSPP. Evidence acquisition: A comprehensiv...

Introduction Fertility and birth control is a worldwide health concerning since it is an important issue regarding economic, religious, or social impacts for couples. Women have plenty options since oral hormonal anticonception were introduced in daily practice. However, men remain restricted to condoms or vasectomy surgery and until now 50% of nat...

Introduction Peyronie's disease (PD) is a penile connective tissue disorder that results in an inflammatory process, fibrotic plaque in the tunica albuginea (TA) and penile curvature. The molecular changes of fibrotic plaque formation are complex and include different cellular/protein mechanisms. Vitamin D (vitD) is a steroid hormone that has uncon...

Introduction Statins are one of the most prescribed classes of drugs worldwide to treat hypercholesterolemia and dyslipidemia. By lowering the level of cholesterol, the precursor of the steroidogenesis pathway, the use of statin could cause a reduction in testosterone levels. Testosterone is essential in biological functions and its reduction can c...

Objective: To evaluate awareness of prostate cancer in the population of the city of São Paulo. Methods: A total of 392 adults were randomly interviewed on public spaces in the city of São Paulo, and answered a questionnaire that addressed demographic questions and specific knowledge about the prostate cancer. A score was used to assess awarenes...

An electronic‐based search was performed with MEDLINE bases through PubMed, Cochrane through Central, and Embase until August 2020 for the purpose of evaluating the impact of the aetiology of obstructive azoospermia on ICSI cycles. In the final analysis, there were 15 cohort studies included, comparing a group of patients with acquired azoospermia...

Given the essential role of sperm DNA integrity for normal embryo development and pregnancy outcome, all efforts should be made to properly counsel infertile men about risks of using sperm with high sperm DNA fragmentation (SDF) for both natural and assisted insemination. Many conditions associated with SDF are modifiable, including varicocele, lif...

Azoospermia is defined as absence of spermatozoa and may be secondary to blocked seminal ducts, known as obstructive azoospermia. Semen quality may be impaired due to factors such as sperm cell DNA fragmentation and presence of antisperm antibodies. The objective of this article was to investigate potential differences in outcomes of in vitro ferti...

In recent years, growing evidence has challenged the notion that sperm quantity and quality are not essential for the success of assisted reproductive technology. DNA fragmentation assessments on ejaculated and testicular sperm harvested from non-azoospermic infertile men have reported a remarkable decrease in DNA damage in spermatozoa directly ret...

A 41-year-old man presented with a 5-year history of primary infertility. The patient denied any hypogonadism symptoms. There was no family history of infertility. His 34-year-old wife presented with no infertility factor. Physical examination demonstrated Body Mass Index (BMI) of 24, normal phallus and bilateral descended testes measuring approxim...

There are few reports describing series of cases about development on laparoscopic urinary diversions no related to cystectomy. The aim of this paper is to show the experience of our reference institutions for treatment of pelvic malignancies when laparoscopic techniques were applied to perform only urinary diversion without cystectomy or pelvic ex...

Acute urinary retention is characterized by a sudden interruption of urinary output; urine is retained in the bladder due to either functional or obstructive anatomic factors, and cannot be voided. The main causes of acute urinary obstruction are benign prostatic hyperplasia, constipation, prostate adenocarcinoma, urethral stenosis, clot retention,...

Context: Gastrointestinal multiple lymphomatous polyposis is a rare type of malignant lymphoma that has aggressive biological behavior, early systemic dissemination and poor prognosis. It is considered to be a manifestation of non-Hodgkin lymphoma and represents the gastrointestinal counterpart of mantle cell nodal lymphoma. Objective: A case of...

PURPOSE: Carcinoembryonic antigen (CEA) determination in gallbladder bile was used in a prospective study concerning the morphological and clinical features of the neoplasm and the occurrence of hepatic metastasis. METHODS: CEA levels in the gallbladder and peripheral blood were studied in 44 patients with colorectal carcinoma and 10 patients with...

OBJETIVO: Analisar, prospectivamente, os resultados da determinação do antígeno carcinoembriário (CEA) na bile vesicular, relacionando-os com os aspectos morfológicos e clínicos da neoplasia e recidiva hepática. MÉTODOS: Os níveis do CEA foram estudados na bile vesicular e no sangue periférico de 44 doentes com carcinoma colorretal e 10 com colelit...

Acute urinary retention is characterized by a sudden interruption of urinary output; urine is retained in the bladder due to either functional or obstructive anatomic factors, and cannot be voided. The main causes of acute urinary obstruction are benign prostatic hyperplasia, constipation, prostate adenocarcinoma, urethral stenosis, clot retention,...