Lelly Yuniarti

• Bandung Islamic University

Background: Tobacco smoke contains a combination of chemicals that could be harmful to the buccal mucosa as the first part of the body that has been exposed. Damage to the buccal epithelial cells has the potential to become a malignant lesion. This study aimed to describe changes in the nuclear epithelial of the buccal mucosa using Pappaniculou sta...

Purpose Artocarpus heterophyllus leaves, rich in phytochemicals, present a promising source of natural bioactive compounds for therapeutic and cosmetic applications. This study evaluated the phytochemical composition, antioxidant potential, and tyrosinase inhibition activities of leaf extracts while assessing the enzyme inhibition properties of key...

Cutibacterium acnes is the primary bacterium responsible for acne vulgaris (AV), an inflammatory skin disease that commonly affects adolescents and young adults. Resistance to antibiotics such as doxycycline has driven the search for alternative treatments based on natural ingredients. Butterfly pea flower extract (Clitoria ternatea L.) is known to...

Pneumonia is an inflammation that attacks the bronchi and alveoli, often occurring in children because their immune system is not fully developed. Pneumonia is still a health problem with a high prevalence in Indonesia. Prevention of pneumonia through vaccination, especially with the PCV vaccine, has been proven effective in reducing the risk of in...

Staphylococcus aureus is a normal flora in the human body, primarily on the skin and respiratory tract, but it can act as a pathogen when the immune system is compromised. Skin infections, bloodstream infections, endocarditis, osteomyelitis, and necrotizing fasciitis are some diseases caused by Staphylococcus aureus infections. The use of penicilli...

The number of abortions each year in Southeast Asia, including Indonesia, is 4.2 million. In Indonesia, spontaneous abortion occurs in 10–15% of 6 million pregnancies and 2,500 of them result in death. The most common factors causing spontaneous abortion are maternal factors, such as maternal age during pregnancy, high parity, multigravidity, histo...

Stunting is a serious nutritional problem in toddlers, which can be influenced by various factors, including maternal nutritional status during pregnancy and birth weight. This study aims to analyze the relationship between low birth weight and maternal nutritional status with the occurrence of stunting in toddlers at the Sindangjawa Health Center,...

Kidney Disease Risk Factors and Clinical Manifestations Among Children in Asia A Systematic Review

Several tests have been developed for Covid-19 diagnosis. One of these tests is a PCR examination with a swab sample. The infection transmission risk to health workers during swab sampling is very high so an adequate protection standard is paramount. A special PPE for Covid-19 specimens’ collection that is safer and can be used for a long time need...

Incidences of cancer have increased sharply throughout the world. The process of finding a targeted cancer drug takes a long time and a lot of money. One method that can help overcome this is computational methods, such as virtual screening. It can be an important alternative in early-stage drug discovery. The aim of this study is to explore and an...

COVID-19 attacks the respiratory system, especially the lung. Therefore, it is necessary to examine the lung radiology of COVID-19 patients to plan the best treatment. This study aimed to describe radiological features in deceased patients at a hospital in Bandung, Indonesia. This study uses secondary data from the medical records of deceased COVID...

Introduction: Corona virus disease 2019 (COVID-19) is a new disease that causes millions of deaths worldwide. The majority of deaths are due to pulmonary degeneration leading to respiratory failure. The gold standard for COVID-19 diagnostics is the examination of the nucleic acid of the SARS-CoV-2 virus using RT-PCR which produces CT values for the...

Introduction: Real time quantitative PCR is the gold standard for detection of SARS-CoV-2 which is specific, sensitive, and simple quantitative. The target of RT-qPCR is to assess the expression level of the SARS-CoV-2 gene through cycle threshold values (CT-value). The purpose of this study was to analyze the association of the level of SARS-CoV-2...

Bajakah wood contains phenolic compounds, flavonoids, tannins, and saponins with anticancer activity. The discovery and development of new drugs require several stages. In the process, there are many possibilities of adding other substances to form new active substances or as solvents that allow drug preparations to be doubtful of halalness. Hence,...

Leukemia yang paling banyak ditemukan pada anak adalah jenis Leukemia Limfoblastik Akut (LLA). Pasien yang mengalami respon lambat setelah pemberian kemoterapi, memiliki risiko relapse lebih besar. Terdapat faktor risiko yang dapat mempengaruhi terjadinya relapse, seperti usia, jenis kelamin, jumlah leukosit, dan klasifikasi morfologi LLA. Peneliti...

In the development of new drugs as candidates for cancer therapy agents, cytotoxic testing is needed as an initial screening to determine the effect of a natural substance in inhibiting tumour cell growth. One of the active compounds of flavonoid derivatives that are being studied as anticancer is a compound derived from clove leaf oil. The purpose...

Breast cancer is the second leading cause of death due to the low success rate of cancer treatment. Breast cancer therapy has not been maximized that encourage researchers to look for effective and selective cancer drugs. The purpose of this study was to determine at the synergistic effects of 1, 2-epoxy-3(3-(3, 4-dimethoxyphenyl)-4H-1-benzopiran-4...

Obesity has become a global issue, and has almost doubled since 1980. One of the strategies chosen for handling or preventing obesity is by diet. Various types of diets are widely developed in the community, such as the ketogenic, Atkins, and mayo diet. There is no definitive data on what diet protocol is the most effective both in the short and lo...

Objective: Cervical cancer is the second most common cancer among women worldwide, with a high mortality rate especially in developing countries. Insufficient treatment for cervical cancer, multiple side effects, and high drug prices encourage researchers to look for effective and selective cancer drugs with appropriate molecular targets. This stud...

The order (sequencing) determinationof DeoxyribonucleicAcid (DNA) bases is the gene’s most basic information, using the methodof Polymerase Chain Reaction (PCR) as its stage. A key factor of successful detection by PCR is specific PCR primer design choice. Thedetection of diversity of Mycobacterium Mannose Receptor (MMR) gene, responsible for recog...

p>Penelitian ini bertujuan untuk mengetahui efek ekstrak air daun sirsak terhadap bobot badan dan kadar kolesterol darah. Penelitian ini menggunakanrancangan acak lengkap dengan 5 kelompok perlakuan masing-masing sebanyak 3 ulangan. Hewan coba berupa tikus galur Wistar sebanyak 15 ekor dibagi menjadi 5 kelompok perlakuan, yaitu kelompok yang diberi...

Infeksi saluran pernapasan akut (ISPA) merupakan penyebab mortalitas utama pada penyakit menular di dunia. Hampir empat juta orang meninggal diakibatkan ISPA di dunia, angka ini terutama terjadi pada bayi dan anak. Sekitar 5% anak di bawah 5 tahun terkena ISPA di Indonesia. Jenis kelamin laki-laki, usia di bawah 5 tahun, dan riwayat berat badan lah...

The effects of soybean extract (Glycine max)on NR2B expression, cognitive vitality and neurotox-icity have not been exclusively reported. Here, we examined the correlation between Glycine max concentration and the N-methyl-D-aspartate(NMDA)receptor NR2B. We observed the brain weight, bodyweight and body movement in animals that recieved soybean ext...