Lei Qin

• Professor
• University of International Business and Economics

As the economic environment becomes increasingly complex, enhancing supply chain resilience is crucial for the operations and long-term development of enterprises. Real-world supply chains, encompassing components such as goods, warehouses, and plants, often contain complex network structures, making resilience analysis a challenging task. This pap...

As the economic environment becomes more complex, improving supply chain resilience is critical for the effective operation and long-term sustainability of businesses. Real-world supply chains, which consist of various components such as goods, warehouses, and plants, often feature intricate network structures that pose challenges for resilience an...

Incorrect labeling is a common issue that often occurs in machine learning applications. If datasets contain noisy labels and these errors are not corrected, the performance of the trained classifiers is affected significantly. In order to address this issue, we present a reliability measurement for labels, which is generated based on crowdsourcing...

Background: -Spontaneous intracranial hemorrhage (ICH) has high fatality while has few proven treatments. We aim at investigating the association between dental scaling (DS) and the risk of ICH. Methods: -In this cohort study, two cohorts were matched by propensity score based on potential confounders. Data from ICH between January 2008 and Dece...

Social stress in daily life and the COVID-19 pandemic have greatly impacted the mental health of the population. Early detection of a predisposition to severe psychological distress is essential for timely interventions. This paper analyzed 4036 samples participating in the 2019–2020 National Health Information Trends Survey (HINTS) and identified...

The use of social media has changed since the outbreak of coronavirus disease 2019 (COVID-19). However, little is known about the gender disparity in social media use for nonspecific and health-specific issues before and during the COVID-19 pandemic. Based on a gender difference perspective, this study aimed to examine how the nonspecific and healt...

Patient-centered communication (PCC) quality is critical to increasing the quality of patient-centered care. Based on the nationally representative data of the Health Information National Trends Survey (HINTS) 2019–2020 (N = 4593), this study combined four machine learning methods, namely, Generalized Linear Models (GLM), Random Forests (Random For...

BACKGROUND With the advent of electronic storage of medical records and the internet, patients can access web-based medical records. This has facilitated doctor-patient communication and built trust between them. However, many patients avoid using web-based medical records despite their greater availability and readability. OBJECTIVE On the basis...

As people pay ever-increasing attention to the problems caused by psychological stress, research on its influencing factors becomes crucial. This study analyzed the Health Information National Trends Survey (HINTS, Cycle 3 and Cycle 4) data (N = 5484) and assessed the outcomes using descriptive statistics, Chi-squared tests, and t-tests. Four machi...

Purpose To predict the fundus tessellation (FT) severity with machine learning methods. Methods A population-based cross-sectional study with 3,468 individuals (mean age of 64.6 ± 9.8 years) based on Beijing Eye Study 2011. Participants underwent detailed ophthalmic examinations including fundus images. Five machine learning methods including ordi...

Background The use of social media in communications regarding cancer prevention is rapidly growing. However, less is known about the general population’s social media use related to cancer screening awareness and behavior for different cancers. Objective We aimed to examine the relationship between social media use and cancer screening awareness...

The effects of temperature and relative humidity on the growth of coronavirus disease 2019 (COVID-19) remain unclear. Data on the COVID-19 epidemic that were analyzed in this study were obtained from the official websites of the National Health Commission of China and the Health Commissions of 31 provinces in China. From January 26 to February 25,...

Background: In this study, we estimated the predictive factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in anesthesiologists performing endotracheal intubation in patients with confirmed SARS-CoV-2. Method: We analyzed data from a survey conducted by the Chinese Society of Anesthesiology Task Force on Airway M...

Tenofovir and entecavir are currently designated as the preferred oral antiviral drugs for chronic hepatitis B. However, only less than 40% of patients can achieve HBeAg seroconversion. We aim at investigating the role of intestinal microbiome in HBeAg seroconversion induced by oral antiviral therapy and describe multi-omics characteristics of HBeA...

Patients with breast cancer can survive and live a long, cancer-free life; however, late complications of treatment, such as second primary malignancies (SPMs), have emerged as a competing cause of death and morbidity. We conducted a long-term population-based cohort study to identify the risk factors for SPMs and specific secondary cancer types af...

Background No evidence is currently available to estimate the outcomes of intensity‐modulated radiation therapy (IMRT) and surgery for patients with early oral cavity squamous cell carcinoma (E‐OCSCC). Methods We recruited patients from the Taiwan Cancer Registry Database who had received a diagnosis of E‐OCSCC. Propensity score matching was perfo...

Purpose To investigate the outcomes of adjuvant whole breast radiation therapy (WBRT) in patients with invasive ductal carcinoma of the breast (breast IDC) receiving preoperative systemic therapy (PST) and breast-conserving surgery (BCS), and their prognostic factors, considering overall survival (OS), locoregional recurrence (LRR), distant metasta...

Background Since the outbreak of COVID-19 in December 2019 in Wuhan, Hubei Province, China, frequent interregional contacts and the high rate of infection spread have catalyzed the formation of an epidemic network. Objective The aim of this study was to identify influential nodes and highlight the hidden structural properties of the COVID-19 epide...

Purpose Although patients aged >70 years are subject to early oral cavity squamous cell carcinoma (E-OCSCC), evidence is currently lacking regarding the probable outcomes of definitive radiotherapy (RT) compared to surgery in this population. Methods We recruited patients aged ≥70 years with a diagnosis of E-OCSCC from the Taiwan Cancer Registry D...

To evaluate the effect of post-mastectomy radiation therapy (PMRT) stratified by clinical tumor (T) or nodal (N) staging and determine predictors of overall survival (OS), locoregional recurrence (LRR), distant metastasis, and disease-free survival (DFS) in patients with breast cancer who received neoadjuvant chemotherapy (NACT) and total mastectom...

To estimate the outcome patterns and predictors of curative surgery for cervical squamous cell carcinoma (SCC) and adenocarcinoma (ADC) for overall survival (OS), locoregional recurrence (LRR), and distant metastasis (DM), we enrolled 4628 patients who had received a diagnosis of cervical SCC or ADC and received curative surgery. Cox regression ana...

Purpose: To estimate the outcomes of definitive concurrent chemoradiotherapy (CCRT) for bulky or advanced-stage cervical squamous cell carcinoma (SCC) and adenocarcinoma (ADC). Patients and methods: We enrolled patients who had been diagnosed as having cervical SCC or ADC and received definitive CCRT. A Cox regression analysis was performed to d...

Objective: We conducted this propensity score (PS)-matched, nationwide, population-based cohort study to estimate the effects of adjuvant oral or intravenous (IV) fluoropyrimidine in patients with high-risk stage II or III colon adenocarcinoma. Design: Using PS matching, we minimized the confounding effects on adjuvant oral or IV fluoropyrimidine o...

Predicting the number of new suspected or confirmed cases of novel coronavirus disease 2019 (COVID-19) is crucial in the prevention and control of the COVID-19 outbreak. Social media search indexes (SMSI) for dry cough, fever, chest distress, coronavirus, and pneumonia were collected from 31 December 2019 to 9 February 2020. The new suspected cases...

Purpose: Although clinicians encounter patients aged ≥70 years with locally advanced oral cavity squamous cell carcinoma (LA-OCSCC), no evidence is available to facilitate decision making regarding treatment for this elderly population. Methods: We selected elderly (≥70 years) patients from the Taiwan Cancer Registry database who had received a dia...

Background: To estimate easily assessed preoperative factors for predicting 90-day mortality in patients with a pancreatic head adenocarcinoma (PHA) receiving a pancreaticoduodenectomy. Methods: We analyzed data from the Taiwan Cancer Registry Database of patients with a PHA who received a pancreaticoduodenectomy. Basic demographic characteristi...

Background: Chronic rhinosinusitis (CRS) have infection, innate immune disorder and chronic inflammation problems which are considered as potential mechanism of tumorigenesis. To estimate cancer risk in CRS using propensity scores matching (PSM) case-control cohort study. Methods: A nationwide retrospective case-control cohort study is conducted...

To analyze the effects of metformin in reducing radiation-induced cardiac toxicity (RICT) risk during adjuvant radiotherapy (RT) after surgery for early-stage breast cancer women. We compare the consecutive occurrence of major heart events (heart failure and coronary artery disease) in women with early-stage breast cancer receiving adjuvant breast...

Purpose: To propose a risk classification scheme for locoregionally advanced (Stages III and IV) head and neck squamous cell carcinoma (LA-HNSCC) by using the Wu comorbidity score (WCS) to quantify the risk of curative surgeries, including tumor resection and radical neck dissection. Methods: This study included 55,080 patients with LA-HNSCC receiv...

Background Few studies have evaluated the risk of oral cavity cancer (OC) in patients with recurrent oral aphthae (ROA) and dry eye syndrome (DES). This study assessed the risk of OC in patients who had received diagnoses of ROA and DES in Taiwan. Methods A population-based frequency-matched case–control study was conducted in which data were anal...

Purpose: No prospective randomized trials have been conducted to date to evaluate the efficacy of palliation of pain or jaundice without treatment, definitive concurrent chemoradiotherapy (CCRT), sequential chemotherapy and radiotherapy (CTRT), or chemotherapy (CT) alone for treating unresectable intrahepatic cholangiocarcinoma (ICC). We designed...

Background Recurrent aphthous stomatitis (RAS) is considered a prophase symptom in patients with specific cancers. This study assessed the association between RAS and subsequent onset of cancer based on a nationwide population‐based database in Taiwan. Materials and Methods We selected study participants from the National Health Insurance Research...

The Hilbert–Huang transform uses the empirical mode decomposition (EMD) method to analyze non-linear and non-stationary data. This method breaks a time series of data into several orthogonal sequences based on differences in frequency. These data components include the intrinsic mode functions (IMFs) and the final residue. Although IMFs have been u...