Léa Longueville- Master of Science
- PhD Student at University of Bergen
Léa Longueville
- Master of Science
- PhD Student at University of Bergen
About
3
Publications
54
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
1
Citation
Introduction
I am a Belgian Ph.D. candidate at the University of Bergen. My project aims to unravel the evolution of the DEG/ENaC family of proteins with a special focus on the ion selectivity and ligand binding of those channels.
Current institution
Education
July 2022 - May 2024
August 2019 - May 2022
Publications
Publications (3)
Background: Tubulointerstitial hypoxia is a key factor for lupus nephritis progression to end-stage renal disease. Numerous aquaporins (AQPs) are expressed by renal tubules and are essential for their proper functioning. The aim of this study is to characterize the tubular expression of AQP1, AQP2 and AQP3, which could provide a better understandin...
Neuropeptides are inter-cellular signaling molecules occurring throughout animals. Most neuropeptides bind and activate G-protein-coupled receptors, but some also activate ionotropic receptors (or “ligand-gated ion channels”). This is exemplified by the tetra-peptide H-Phe-Met-Arg-Phe-NH2 (FMRFamide (FMRFa)), which activates mollusk and annelid FMR...
Background
Lupus nephritis is a severe and life-threatening manifestation of systemic lupus erythematosus. Tubulointerstitial hypoxia is a key factor in the progression to end-stage renal disease. Numerous aquaporins are expressed by renal tubules and are essential for their proper functioning. Several mouse models have shown their involvement in t...
