Laurent Malisoux

Laurent Malisoux
LIH Luxembourg Institute of Health | CRP Santé · Department of Precision Health

MSc, PhD

About

120
Publications
42,431
Reads
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1,811
Citations
Citations since 2016
88 Research Items
1507 Citations
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2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
Introduction
I am a sports scientist with background in exercise and muscle physiology, biomechanics, sports medicine and epidemiology. I am the leader of the Physical Activity, Sport & Health research group at the Department of Precision Health of the Luxembourg Institute of Health. My research activities focuses on both the prevention of sports injuries (mainly in running), and the assessment of physical activity using raw accelerometry data. I am Associate Editor of the European Journal of Sport Science.
Additional affiliations
January 2019 - present
LIH Luxembourg Institute of Health
Position
  • Group Leader
Description
  • Physical Activity, Sport & Health research group
January 2017 - December 2019
Lunex University
Position
  • Lecturer
Description
  • Module of Biomechanics
September 2013 - December 2018
LIH Luxembourg Institute of Health
Position
  • Researcher
Description
  • Sports Medicine Research Laboratory
Education
September 2002 - June 2003
Université Catholique de Louvain - UCLouvain
Field of study
  • Health sciences with a specialization in exercise sciences
September 2000 - August 2006
Université Catholique de Louvain - UCLouvain
Field of study
  • Physical Education and Sport
September 1996 - June 2000
Université Catholique de Louvain - UCLouvain
Field of study
  • Physical Education and Sports

Publications

Publications (120)
Article
Full-text available
Physical activity (PA) is a complex human behaviour, which implies that multiple dimensions need to be taken into account in order to reveal a complete picture of the PA behaviour profile of an individual. This scoping review aimed to map advanced analytical methods and their summary variables, hereinafter referred to as wearable‐specific indicator...
Article
Full-text available
Cushioning systems in running shoes are used assuming that ground impact forces relate to injury risk and that cushioning materials reduce these impact forces. In our recent trial, the more cushioned shoe version was associated with lower injury risk. However, vertical impact peak force was higher in participants with the Soft shoe version. The pri...
Article
Full-text available
In a recent randomized trial investigating running shoe cushioning, injury risk was greater in recreational runners who trained in the shoe version with greater cushioning stiffness (Stiff) compared to those using the Soft version. However, vertical impact peak force (VIPF) was lower in the Stiff version. To investigate further the mechanisms invol...
Article
Background Running biomechanics may play a role in running-related injury development, but to date, only a few modifiable factors have been prospectively associated with injury risk. Purpose To identify risk factors among spatiotemporal and ground-reaction force characteristics in recreational runners and to investigate whether shoe cushioning mod...
Article
Background Shoe cushioning is expected to protect runners against repetitive loading of the musculoskeletal system and therefore running-related injuries. Also, it is a common belief that heavier runners should use footwear with increased shock absorption properties to prevent injuries. Purpose The aim of this study was to determine if shoe cushio...
Article
Full-text available
Objective To provide consensus on how to plan, organize and implement exercise-based injury prevention program (IPP) in sports. Design Delphi. Setting LimeSurvey platform. Participants Experienced sports physical therapists from the International Federation of Sports Physical Therapy member countries. Main outcome measures Factors related to sp...
Article
Full-text available
Objective To investigate if the physical activity (PA) prior to infection is associated with the severity of the disease in patients positively tested for COVID-19, as well as with the most common symptoms. Design A cross-sectional study using baseline data from a prospective, hybrid cohort study (Predi-COVID) in Luxembourg. Data were collected fr...
Article
Full-text available
Background: Disturbances of glycemic control and large glycemic variability have been associated with increased risk of type 2 diabetes in the general population as well as complications in people with diabetes. Long-term health benefits of physical activity are well documented but less is known about the timing of potential short-term effects on...
Article
Full-text available
Given the rapid increase in the incidence of cardiometabolic conditions, there is an urgent need for better approaches to prevent as many cases as possible and move from a one-size-fits-all approach to a precision cardiometabolic prevention strategy in the general population. We used data from ORISCAV-LUX 2, a nationwide, cross-sectional, populatio...
Article
Full-text available
Aim To analyze the association of objective and subjective sleep measures with HbA1c and insulin sensitivity in the general population. Methods Using a cross-sectional design, data from 1028 participants in the ORISCAV-LUX-2 study from the general population in Luxembourg were analyzed. Objective sleep measures were assessed using accelerometers w...
Article
Objective: To investigate if motion control shoes reduce the risk of pronation-related injuries in recreational runners. Design: Secondary analysis of a randomized controlled trial of the effect of shoes on running injuries. Methods: 372 recreational runners were randomized to receive either standard neutral or motion control shoes and were fo...
Article
Full-text available
The main objective was to investigate if the cumulative load of the lower limbs, defined as the product of external load and step rate, could be predicted using spatiotemporal variables gathered with a commercially available wearable device in running. Therefore, thirty‐nine runners performed two running tests at 10 and 12 km/h, respectively. Spati...
Article
Full-text available
Background Physical activity (PA) is a complex multidimensional human behaviour. Currently, there is no standardised approach for measuring PA using wearable accelerometers in health research. The total volume of PA is an important variable because it includes the frequency, intensity and duration of activity bouts, but it reduces them down to a si...
Preprint
BACKGROUND Physical Activity (PA) is a modifiable lifestyle factor that can be targeted for increasing energy expenditure and promoting weight loss. However, results regarding the efficient PA amount for weight loss remain heterogeneous. Wearable activity trackers constitute a valuable opportunity to obtain objective measurements regarding PA and s...
Article
Full-text available
Background Physical activity (PA) is a modifiable lifestyle factor that can be targeted to increase energy expenditure and promote weight loss. However, the amount of PA required for weight loss remains inconsistent. Wearable activity trackers constitute a valuable opportunity to obtain objective measurements of PA and study large populations in re...
Conference Paper
Full-text available
Introduction. Ground reaction force (GRF) is a key parameter to study running mechanics. Previous studies which assessed the effect of sex did not control for major factors also influencing GRF like speed or anthropometrics. The purpose of the study was to investigate the running GRF differences between male and female, while controlling for other...
Article
Full-text available
Leisure-time running is one of the most popular forms of physical activity around the world. It can be practiced almost everywhere and requires mainly a pair of "appropriate" running shoes. However, the term appropriate is ambiguous, and the properties of running footwear have always generated hot debates among clinicians, coaches, and athletes, wh...
Chapter
It is popular belief that the relationship between running footwear and running injuries is direct and causal. This idea is wrong and has been nurtured by the running shoe industry ever since the appearance of the modern running shoe. Still, the latter may well influence the relationship between training load and injury occurrence, thus acting as a...
Article
In a recent randomized trial including 800+ recreational runners, injury risk was lower in those who received the Soft shoe version compared to those using the Hard version (Hazard ratio=1.52; 95% Confidence Interval=1.07-2.16). Here, we investigated the effect of shoe cushioning on ground reaction forces (GRF) and spatiotemporal parameters in the...
Chapter
Physical ergonomics of distance running footwear is a hotly debated topic of discussion. This chapter focuses on recreational distance running and the role of footwear on performance and, especially, protection against injury. Running economy is the surrogate measure of choice to evaluate distance running performance. Shoes with a mass lower than 2...
Article
Full-text available
Objective: This pilot randomized controlled trial (RCT) aimed at evaluating the feasibility and potential efficacy of a motivational interviewing (MI) intervention to increase physical activity (PA) behavior in cancer patients. Methods: Participants were randomly assigned to an experimental group with standard care plus 12 MI sessions within 12...
Article
Background In randomised controlled trials (RCTs) of interventions that aim to prevent sports injuries, the intention-to-treat principle is a recommended analysis method and one emphasised in the Consolidated Standards of Reporting Trials (CONSORT) statement that guides quality reporting of such trials. However, an important element of injury preve...
Article
Full-text available
Objective: Frailty is a dynamic state of vulnerability in the elderly. We examined whether individuals with overt diabetes or higher levels of HbA1c or fasting plasma glucose (FG) experience different frailty trajectories with aging. Research design and methods: Diabetes, HbA1c, and FG were assessed at baseline, and frailty status was evaluated...
Article
Full-text available
Background It is challenging to manage data collection as planned and creation of opportunities to adapt during the course of enrolment may be needed. This paper aims to summarize the different sampling strategies adopted in the second wave of Observation of Cardiovascular Risk Factors (ORISCAV-LUX, 2016–17), with a focus on population coverage and...
Article
Background: Sudden changes in training load may play a key role in the development of running-related injury (RRI). Because the injury mechanism depends on the runner's musculoskeletal load capacity, the running schedule followed prior to sudden change in training load may influence the amount of change that a runner can tolerate before the runner...
Article
Full-text available
Background: Sudden changes (increases and decreases) in training load have been suggested to play a key role in the development of running-related injuries. However, the compiled evidence for an association between change in training load and running-related injury does not exist. Purpose: The purpose of the present systematic review was to comp...
Article
The aim of the study was to determine the effect of α-actinin-3 (ACTN3) deficiency (XX) on muscle damage induced by an eccentric exercise bout. In this purpose, 4 RR and 4 XX individuals performed an intensive eccentric knee flexion exercise on an isokinetic dynamometer. Muscle biopsies, blood and pain scores were taken before and after the exercis...
Article
Objectives: The health benefits from participation in half-marathon is challenged by a yearly running-related injury (RRI) incidence proportion exceeding 30%. Research in injury etiology is needed to successfully prevent injuries. The body's load capacity is believed to play an essential role for injury development. Therefore, the purpose of Proje...
Article
Objective: To discuss the interpretability of non-causal associations to sports injury development exemplified via the relationship between navicular drop (ND) and running-related injury (RRI) in novice runners using neutral shoes. Design: 1-year prospective cohort study. Setting: Denmark. Participants: 926 novice runners, representing 1852...
Article
Full-text available
Background Frail elderly people experience elevated mortality. However, no consensus exists on the definition of frailty, and many frailty scores have been developed. The main aim of this study was to compare the association between 35 frailty scores and incident cardiovascular disease (CVD), incident cancer, and all-cause mortality. Also, we aimed...
Data
Adjustment covariates for model 3. (DOCX)
Data
Mortality hazard ratios of frailty scores assessed in intervals from 1 to 7 years: Age-adjusted model and continuous analysis. (DOCX)
Data
Mortality hazard ratios of frailty scores assessed in intervals from 1 to 7 years: Age-adjusted model and categorical analysis. (DOCX)
Data
Cardiovascular events hazard ratios of frailty scores (n = 4,554) calculated at median time follow-up (2.5 years). (DOCX)
Data
Cardiovascular hazard ratios of frailty scores assessed in intervals from 1 to 7 years: Age-adjusted model and categorical analysis. (DOCX)
Data
Cardiovascular hazard ratios of frailty scores assessed in intervals from 1 to 7 years: Age-adjusted model and continuous analysis. (DOCX)
Data
Cancer hazard ratios of frailty scores (n = 4,792) calculated at median time follow-up (2.5 years). (DOCX)
Data
Cancer hazard ratios of frailty scores assessed in intervals from 1 to 7 years: Age-adjusted model and continuous analysis. (DOCX)
Data
Cancer hazard ratios of frailty scores assessed in intervals from 1 to 7 years: Age-adjusted model and categorical analysis. (DOCX)
Data
Discriminative assessment of cardiovascular models using Harrell's C statistic (n = 4,554). (DOCX)
Data
Discriminative assessment of cancer models using Harrell's C statistic (n = 4,792). (DOCX)
Data
Sensitivity analysis: Mortality hazard ratios of frailty scores (n = 5,253). (DOCX)
Data
Mortality hazard ratios of frailty scores in men (n = 2,377) calculated at median time follow-up (3.5 years). (DOCX)
Data
Mortality hazard ratios of frailty scores in participants of 70 years and younger (n = 2,758) calculated at median time follow-up (3.5 years). (DOCX)
Data
Mortality hazard ratios of frailty scores in women (n = 2,917) calculated at median time follow-up (3.5 years). (DOCX)
Data
Mortality hazard ratios of frailty scores in participants older than 70 years (n = 2,536) calculated at median time follow-up (3.5 years). (DOCX)
Conference Paper
A concerning number of new recruits enrolled in the Luxembourg army do not successfully complete their basic military training (BMT). As a military career is characterized by high physical demands, the selection process of new recruits is strongly based on physical fitness entry tests. The purpose of this ongoing prospective study is to investigate...
Article
Full-text available
Background: Participation in half-marathon has been steeply increasing during the past decade. In line, a vast number of half-marathon running schedules has surfaced. Unfortunately, the injury incidence proportion for half-marathoners has been found to exceed 30% during 1-year follow-up. The majority of running-related injuries are suggested to de...
Article
Full-text available
We aim to determine the influence of sports floorings and sports shoes on impact mechanics and performance during standardised jump tasks. Twenty-one male volunteers performed ankle jumps (four consecutive maximal bounds with very dynamic ankle movements) and multi-jumps (two consecutive maximal counter-movement jumps) on force plates using minimal...
Article
Full-text available
Introduction Repetitive loading of the musculoskeletal system is suggested to be involved in the underlying mechanism of the majority of running-related injuries (RRIs). Accordingly, heavier runners are assumed to be at a higher risk of RRI. The cushioning system of modern running shoes is expected to protect runners again high impact forces, and t...