Laura Campo-Deaño

Laura Campo-Deaño
University of Porto | UP · Departamento de Engenharia Mecânica

PhD

About

59
Publications
7,616
Reads
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1,018
Citations
Additional affiliations
March 2012 - June 2012
University of Oxford
June 2010 - present
University of Porto
October 2008 - March 2010
KU Leuven

Publications

Publications (59)
Article
Blood plasma (BP) is a borderline non-Newtonian fluid. Few studies have characterized the rheology of BP and even less focused on understanding its subtle viscoelastic traits, which were only somewhat recently acknowledged. We use passive microrheology to measure the bulk response of human plasma samples under shear at body and ambient temperatures...
Article
Full-text available
Microbots have been considered powerful tools in minimally invasive medicine. In the last few years, the topic has been highly studied by researchers across the globe to further develop the capabilities of microbots in medicine. One of many applications of these devices is performing surgical procedures inside the human circulatory system. It is ex...
Article
Full-text available
This study represents a pioneering work on the extensional magnetorheological properties of human blood analogue fluids loaded with magnetic microparticles. Dynabeads M-270 particles were dispersed in Newtonian and viscoelastic blood analogue fluids at 5% wt. Capillary breakup experiments were performed, with and without the influence of an externa...
Article
Motivated by the recent developments in the research of untethered microrobots for performing minimally invasive procedures inside blood vessels, we have devised a novel microfluidic experiment for studying the haemodynamics around different types of cylinders confined inside a straight, long, 270×100μm channel. Two test sections are studied: flow...
Article
The present works contributes with a rheological characterization of the most commonly used polymers and solvents to formulate amorphous solid dispersions by means of spray drying process: copovidone, hydroxypropyl methylcellulose (HPMC), hydroxypropyl methylcellulose acetate succinate (HPMCAS) and a copolymer of methacrylic acid and methyl methacr...
Article
Full-text available
This is the supplementary information of the research paper “Haemodynamics around confined microscopic cylinders” by Rodrigues et al. [1]. The critical overlap concentration of entanglement of polymer coils indicates whether a polymer solution is dilute or semidilute. Here, the reader will find the determination of c* for xanthan gum aqueous soluti...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Full-text available
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Article
Dense suspensions of model hard-sphere (HS)-like colloids, with different particle sizes, are examined experimentally near and in the glass state, under shear and extensional rheology. Under steady shear flow, we detect both continuous and discontinuous shear thickening (DST) above a critical shear rate (or shear stress), depending on the particle...
Chapter
Full-text available
Afuega’l Pitu atroncau cheese, Blancu (B) and Roxu (R) varieties, were collected at 30 days of ripening from 9 farms (B1−B9 and R1−R9) to determine the biochemical and linear viscoelastic parameters, as well as the microstructure. B and R samples exhibited fused casein particles in the protein matrix with a high packing effect and different fat dis...
Chapter
How does flow inside a microfluidic device behave when passing by a pressure tap? Will its natural state be disrupted by any means? We seek to answer these questions and assess the consequences (if any) of attaching pressure taps to microchannels. To do so, streakline photography was performed for flow patterns visualisation in the close proximity...
Chapter
When performing extensional ER tests for the characterization of electro-rheological fluids, the time between applying the electric field and triggering the experiment (delay time) plays an important role in ER behaviour of the sample. The current study investigates the delay time effect in extensional ER characterization. The ER sample used in the...
Book
This book presents the proceedings of IBEREO 2019. This conference addresses the most recent trends in rheology with a special emphasis on both basic science and industrial applications. Papers presented cover different perspectives, like experimental, theoretical and numerical. Topics include Microfluidics and microrheology, Food, Cosmetics and Ph...
Technical Report
Full-text available
I would like to share with you that we are currently equipped in our research group with magnetorheological and electrorheological cells (both patents pending) specifically designed to work with the Capillary BreakUp Extensional Rheometer (CaBER). If you are interested in collaborating with us, please send me a message. "Capillary Breakup Extension...
Chapter
Particle tracking applied to video passive microrheology is conventionally done through methods that are far from being automatic. Creating mechanisms that decode the image set properties and correctly detect the tracer beads, to find their trajectories, is fundamental to facilitate microrheology studies. In this work, the adequacy of two particle...
Article
Full-text available
Fused Filament Fabrication is an extrusion deposition technique in which a thermoplastic filament is melted, pushed through a nozzle and deposited to build, layer-by-layer, custom 3D geometries. Despite being one of the most widely used techniques in 3D printing, there are still some challenges to be addressed. One of them is the accurate control o...
Article
Structural (cryo-scanning electron microscopy), and viscoelastic changes (dynamic rheometry), with storage time in Afuega'l Pitu cheese Blancu (B) and Roxu (R) varieties were observed. Biochemical parameters were also measured. pH, fat, and protein content did not change during the storage time for B and R varieties. R micrographs showed large fuse...
Article
Full-text available
Measuring fluid pressure in microchannels is difficult and constitutes a challenge to even the most experienced of experimentalists. Currently, to the best of the authors’ knowledge, no optimal solution are being used for the design of pressure taps, nor guidelines concerning their shape and its relation with the accuracy of the readings. In an att...
Chapter
The number of scientific studies related with microfluidics techniques have been increasing in the last decade due to the great advantages they provide in the characterization of complex fluid flows. Obtaining precise and accurate results, especially in the experimental field, is of great importance. However, this is not always an easy task. In thi...
Article
Suspensions of healthy and pathological red blood cells (RBC) flowing in microfluidic devices are frequently used to perform in vitro blood experiments for a better understanding of human microcirculation hemodynamic phenomena. This work reports the development of particulate viscoelastic analogue fluids able to mimic the rheological and hemorheolo...
Article
Full-text available
The use of microbots in biomedicine is a powerful tool that has been an object of study in the last few years. In the special case of using these microdevices in the human circulatory system to remove clots or to deliver drugs, the complex nature of blood flow must be taken into account for their proper design. The dynamic performance, defined in t...
Patent
The present disclosure relates to the customization of a composite layer material for absorbing or dissipating mechanical energy under impacts or vibrations. The composite layer material comprises at least a support layer of a resilient material, said support layer having recessed fluid-tight microchannels comprising a fluid, wherein the channel se...
Article
A new experimental setup for the study of the flow dynamics around 3D microbot prototypes in a straight microchannel has been developed. The ultimate aim of this work is focused on the analysis of the morphology of different microbot prototypes to get a better insight of their efficiency when they swim through the main conduits of the human circula...
Article
Full-text available
The interest in the development of blood analogues has been increasing recently as a consequence of the increment in the number of experimental hemodynamic studies and the difficulties associated with the manipulation of real blood in vitro because of ethical, economical or hazardous issues. Although one-phase Newtonian and non-Newtonian blood anal...
Conference Paper
Axial migration of individual red blood cells (RBCs) is a well known effect that happens in microchannels with dimensions below 300 μm. This effect is known as the Fåhræus-Lindqvist effect gives place to a cell free layer (CFL) of plasma located around the walls of the microchannel [1]. Several flow studies regarding the CFL measurement exist in in...
Article
Cerebrovascular accidents are the third most common cause of death in developed countries. Over recent years, CFD simulations using medical image-based anatomical vascular geometries have been shown to have great potential as a tool for diagnostic and treatment of brain aneurysms, in particular to help advise on the best treatment options. This wor...
Article
Many artificial and natural fluids contain macromolecules, particles or droplets that impart complex flow behaviour to the fluid. This complex behaviour results in a non-linear relationship between stress and deformation standing in between Newton’s law of viscosity for an ideal viscous liquid and Hooke’s law for an ideal elastic material. Such non...
Article
The non-Newtonian properties of blood are of great importance since they are closely related with incident cardiovascular diseases. A good understanding of the hemodynamics through the main vessels of the human circulatory system is thus fundamental in the detection and especially in the treatment of these diseases. Very often such studies take pla...
Article
Full-text available
The non-Newtonian properties of blood are of great importance since they are closely related with incident cardiovascular diseases. A good understanding of the hemodynamics through the main vessels of the human circulatory system is thus fundamental in the detection and especially in the treatment of these diseases. Very often such studies take pla...
Article
Many hydrogel materials of interest are homogeneous on the micrometer scale. Electrospinning, the formation of sub-micrometer to micrometer diameter fibers by a jet of fluid formed under an electric field, is one process being explored to create rich microstructures. However, electrospinning a hydrogel system as it reacts requires an understanding...
Article
Full-text available
A gelation process was seen to occur when Boger fluids made from aqueous solutions of polyacrylamide (PAA) and NaCl flowed through porous media with certain characteristics. As these viscoelastic fluids flow through a porous medium, the pressure drop across the bed varies linearly with the flow rate, as also happens with Newtonian fluids. Above a c...
Article
In this work we focus on the development of low viscosity Boger fluids and assess their elasticity analyzing the flow through a microfluidic hyperbolic contraction. Rheological tests in shear and extensional flows were carried out in order to evaluate the effect of the addition of a salt (NaCl) to dilute aqueous solutions of polyacrylamide at 400,...
Article
Full-text available
In this study, two microfluidic devices are proposed as simplified 1-D microfluidic analogues of a porous medium. The objectives are twofold: firstly to assess the usefulness of the microchannels to mimic the porous medium in a controlled and simplified manner, and secondly to obtain a better insight about the flow characteristics of viscoelastic f...
Article
High-throughput screening of material properties of therapeutic hydrogelators enables the engineering of these materials for applications such as wound healing and tissue regeneration. Designing material to mimic biologically relevant environments, such as the extracellular matrix, requires knowledge of both the hydrogelation reaction and the final...
Article
AbstractWe monitor the capillary thinning and breakup of low viscous liquid filaments with high speed imaging to determine the relaxation time of dilute polymer solutions in extension. The induction of filament thinning by a slow extension of a liquid bridge beyond the static stability limit enables one to create axially symmetric thinning profiles...
Article
Full-text available
Functionality of squid surimi (Dosidicus gigas) made by two methods (isoelectric precipitation A, and acid washing, B) and stored for 6 months at −15 °C, was analysed as a function of several cryoprotectants. The cryoprotectant effect was studied in terms of the ability to form suwari gels (SA and SB) from the two kinds of surimi. Chemical analyses...
Article
The influence of the amount of egg albumen contained as a gelation agent in crab sticks made from Alaska Pollock or Pacific Whiting surimi on their viscoelastic properties was examined. Dynamic oscillatory and transient tests allowed a variety of parameters to be measured in order to establish the intensity of the interactions in the protein networ...
Article
Full-text available
Two new methods were designed for making surimi from giant squid (Dosidicus gigas) muscle. The first is based on protein precipitation at the isoelectric point (type A), and the second on washing with an acid solution (type B). Chemical analyses (e.g. protein solubility, electrophoretic profile), structural analyses (scanning electronic microscopy)...
Article
Influence of the acid (Type A) and alkali (Type B) solubilization of muscle proteins in the viscoelastic properties of surimi and surimi gels made from horse mackerel (Trachurus trachurus) muscle were evaluated. Stress and frequency sweep tests showed that surimi from method B presents higher viscoelastic moduli, lowest values of phase angle and...
Article
Rheological changes during five months of frozen storage of horse mackerel (Trachurus trachurus) surimi elaborated by acid (Type A) and alkali (Type B) treatment, and their ability to form gels were evaluated. Frozen storage provoked a sligthly increase of rigidity and toughness in surimi B due to the loss of water holding capacity. This effect on...
Article
Changes in viscoelastic properties as a function of the wheat starch content of crab sticks from Alaska Pollock and Pacific Whiting surimi determined from transient and oscillatory measurements were studied. Based on the frequency dependence of the complex shear modulus (G∗), the two types of sticks were discriminated in terms of gel stiffness (An)...
Article
Full-text available
This work studies the flow behavior and related pressure losses of viscoelastic polymer solutions in microchannels with two different sequences of contraction/expansion, disposed in a symmetric and an asymmetric arrangement, respectively. These microfluidic devices are proposed as simplified microchannel analogues for the flow of Newtonian and visc...

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Projects

Projects (4)
Project
FERROCLEAN is a multidisciplinary project gathering experts in material science, transport phenomena, and marine and environmental sciences that aims at developing knowledge to improve the efficiency of the magnetic cleaningup process of oil spills. This will be achieved through the following objectives: 1) provide an experimental tool for rheological characterization of magnetic fluids simultaneously undergone to an extensional flow and to the presence of a magnetic field, which intensity and orientation would be tunable; 2) perform a systematic and full rheological characterization under shear and extensional flow of different ferrofluids, i.e. size and surface chemistry of particles, carrier fluid, intensity of magnetic field and orientation; and, finally, 3) assess the relationship between efficiency of the Halbach array in water cleanup, including the decrease in chemical load and toxicity potential, with the rheological properties of the ferrofluids.
Project
The final aim of this project is to optimize the printability of 2D-material-based (graphene, TMDs, and h-BN) inks to overcome the current limitations related with printed electronics and allow them going from niche to mainstream market. We will perform an in-depth rheological characterization of new formulations and 2D-inks currently available in the literature for printed electronics. The three processes associated with the inkjet printing technologies (continuous inkjet printing, drop-on-demand, and electroestatic inkjet printing) will be assessed in terms of fluidic deficiencies by a thorough fluid-flow characterization at lab-scale.