Larysa Lenchyk

Larysa Lenchyk
National University of Pharmacy · Department of Chemistry of Natural Compounds

Doctor of Science (Pharmacy)

About

31
Publications
4,410
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172
Citations
Citations since 2016
31 Research Items
172 Citations
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20162017201820192020202120220204060
20162017201820192020202120220204060
20162017201820192020202120220204060
Introduction
Skills and Expertise

Publications

Publications (31)
Article
Full-text available
The study aims to review the involvement of differentdietary habits in Laotian, Cambodian, and Vietnamesepopulations in reducing COVID19 impact.Materials and Methods. The methods of collection,systematization, analysis and generalization of information data have been used. The analysis ofliterature in scientific databases and analytical platforms b...
Article
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a member of the coronavirus family and could induce the viral disease named coronavirus disease 2019 (COVID-19). The disease became a pandemic after the reported first case in December 2019. In this review, we highlighted the herbal substances with antiviral effects. To examine peer-re...
Article
Full-text available
The current review provides an up-to-date analysis of scientific data on astaxanthin (ASX) sources and experimental studies on its health benefits as a potent antioxidant in the aging process. ASX is a liposoluble carotenoid nutrient and reddish-orange pigment, naturally synthesized by numerous microalgae, yeasts, and bacteria as secondary metaboli...
Article
Full-text available
Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic effects, and possible health benefits in vivo and in vitro, as well as reported clinical studies. Considering their free-radical scavenging and anti-inflammatory propert...
Article
Full-text available
Rapid industrial and technological development has impacted ecosystem homeostasis strongly. Arsenic is one of the most detrimental environmental toxins and its management with chelating agents remains a matter of concern due to associated adverse effects. Thus, safer and more effective alternative therapy is required to manage arsenic toxicity. Bas...
Article
Full-text available
Chronic exposure to arsenic (As) compounds leads to its accumulation in the body, with skin lesions and cancer being the most typical outcomes. Treating As-induced diseases continues to be challenging as there is no specific, safe, and efficacious therapeutic management. Therapeutic and preventive measures available to combat As toxicity refer to c...
Article
Elevated plasma levels of homocysteine (Hcy) are a recognized risk factor for stroke. This relationship represents one aspect of the debated `Hcy hypothesis’. Elevated Hcy may be an independent and treatable cause of atherosclerosis and thrombotic vascular diseases. Further observations indicate that proper dietary supplementation with B-vitamins d...
Article
Full-text available
(1) Background: Italy accounts for more than 150,000 deaths due to the COVID-19 pandemic, leading the top rank in SARS-CoV-2-caused deceases in Europe. A survey on the different ways by which the COVID-19 pandemic emergency was managed in the foreign European countries compared to Italy is the purpose of this paper. (2) Methods: A literature search...
Article
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This article focuses on the role pharmaceutical scientists play in achieving social well-being, in particular in the formation of a healthy lifestyle as a value orientation among students and the public in historical retrospect. The following set of research methods was used: a general scientific method, and a historical (chronological, logico-hist...
Article
Prunus domestica - is one of the main fruit crops in Ukraine with a production of about 200 tons per year. In the world over then 2000 varieties of this plant are grown. In Ukraine, the following varieties of plums are zoned: Anna Shpet, Renklod Altana, Ugorka Stanley, Ugorka Italian, Ugorka Azhanska, and others. This plant is the valuable source o...
Article
Full-text available
The COVID‐19 pandemic is a highly dramatic concern for mankind. In Italy, the pandemic exerted its major impact throughout the period of February to June 2020. To date, the awkward amount of more than 131,000 deaths have been reported. Post‐mortem autopsy was performed on a very modest number of patients who died from COVID‐19 infection, leading to...
Chapter
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Liver, as a leading site of metabolism, utilizes various biochemical pathways for energy production and detoxification. Hepatoprotective agents comprise the basis of non-specific pathogenetic therapy of liver diseases. These drugs prevent the damages of the structure and functions of the liver in various pathological conditions, accelerate the rege...
Article
Full-text available
Arsenic (As) is widely used in the modern industry, especially in the production of pesticides, herbicides, wood preservatives, and semiconductors. The sources of As such as contaminated water, air, soil, but also food, can cause serious human diseases. The complex mechanism of As toxicity in the human body is associated with the generation of free...
Article
Full-text available
The role of phytochemicals as potential prodrugs or therapeutic substances against tumors has come in the spotlight in the very recent years, thanks to the huge mass of encouraging and promising results of the in vitro activity of many phenolic compounds from plant raw extracts against many cancer cell lines. Little but important evidence can be re...
Article
Qualitative composition and content of flavonoids and hydroxycinnamic acids in cherry (Prunus cerasus) fruits extract have been studied by HPLC, system Shimadzu LC-20 Prominence module system equipped with LC-20AD quaternary pump, СТО-20А column oven, SIL-20A autosampler, SPD-M20A diode-array detector, Luna C 18 (4.6mm×150mm, i.d. 5 mkm) column fro...
Article
Full-text available
Aim. The aim of our research was fractionation of polysaccharide complexes from fresh plum fruits, comparative study content of neutral sugars in it, element composition of plum fruit and investigation of influence of fibers and water soluble polysaccharide complex (WSPC) on histostructure of rats liver in conditions of ethanol intoxication Methods...
Article
Qualitative composition and content of phenolic compounds and monosaccharides in the dry extract obtained from cherry leaves before and after hydrolysis have been studied by HPLC, with the Agilent Technologies chromatograph (model 1100)completed with continuous-flow vacuum degasifier G1379A, 4-channel pump of low pressure gradientG13111A, automatic...
Article
Full-text available
Aim. The aim of our research was investigation of phenolic constituents, free and connected sugars of the cherry shoots dry extract by the HPLC method and determination of acute toxicity and anti-inflammatory activity of the extract. Methods. Qualitative composition and content of phenolic compounds and sugars in the cherry shoots dry extract were...
Article
Bird cherry, Prunus padus is widely distributed in Ukrainian forests. Fresh and dried fruits are highly reputed in Russian, Belarus and Ukrainian ethnoscience medicine for astringent, nutritive and digestive properties and recommended for common cold, strengthening stomach in gastritis, colic, diarrhea, as anesthetic and disinfectant, to improve co...
Article
Introduction. Bird cherry Padus avium Mill, Rosaceae, is widespread in Ukraine, especially in forests and foreststeppe areas. Bird cherry fruits have long been used in medicine and is a valuable medicinal raw materials. They stated to posess astringent, anti-inflammatory, phytoncidal properties. Bird cherry fruits are included in the USSR Pharmacop...

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Projects

Projects (2)
Project
Creation new medicines on the base of substances with laxative, anti-inflammatory, diuretic and hepatoprotective activities obtained from plum, almond, cherry and apricot
Project
To study the effects of food constituents on disease