
Larisa SheloukhovaOkinawa Institute of Science and Technology Graduate University | OIST
Larisa Sheloukhova
Doctor of Philosophy
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Publications (4)
Nervous systems of bilaterian animals generally consist of two cell types: neurons and glial cells. Despite accumulating data about the many important functions glial cells serve in bilaterian nervous systems, the evolutionary origin of this abundant cell type remains unclear. Current hypotheses regarding glial evolution are mostly based on data fr...
In bilaterian central nervous systems, coordination of neurotransmission by glial cells enables highly sophisticated neural functions. The diversity of transcription factors (TFs) involved in gliogenesis suggests multiple evolutionary origins of various glial cell types of bilaterians. Many of these TFs including the glial cells missing (Gcm) are a...
In bilaterian central nervous systems, coordination of neurotransmission by glial cells enables highly sophisticated neural functions. However, it is unclear when glial cells became functional in metazoan evolution. Because cnidarians are the closest outgroup to the Bilateria, we analyzed the function of glial cells missing ( Gcm) , the core bilate...
Three parkinsonism models using neurotoxin 6-OHDA and pesticides rotenone and paraquat were reproduced in Wistar rats and parameters of astrocyte processes in the striatum (axon number and length, area occupied by them, and axon branching pattern) detected by immunohistochemical reaction for acid glial fibrillary protein were studied by computer mo...