Laouen Mayal Louan Belloli

University of Buenos Aires | UBA · Department of Computer Sciences (FCEN)

Attention shapes our consciousness content and perception by increasing the probability of becoming aware and, or, better encode a selection of the incoming inner or outer sensory world. Engaging interoceptive and exteroceptive attention should elicit distinctive neural responses to visceral and external stimuli and could be useful in detecting cov...

Severely brain-injured patients may enter a spectrum of conditions collectively known as disorders of consciousness (DoC). This spectrum includes clinical categories such as unresponsive wakefulness syndrome or minimally conscious state, where the behavioral assessment of consciousness can often be deceptive. To bridge this dissociation, neuroimagi...

Introduction: The Toolkit to Examine Lifelike Language (TELL) is a web-based application providing speech biomarkers of neurodegeneration. After deployment of TELL v.1.0 in over 20 sites, we now introduce TELL v.2.0. Methods: First, we describe the app’s usability features, including functions for collecting and processing data onsite, offline, and...

Disorders of consciousness (DoC) represent a challenging and complex group of neurological conditions characterised by profound disturbances in consciousness. The current range of treatments for DoC is limited. This has sparked growing interest in developing new treatments, including the use of psychedelic drugs. Nevertheless, clinical investigatio...

Accurately predicting functional outcomes for unresponsive patients with acute brain injury is a medical, scientific and ethical challenge. This prospective study assesses how a multimodal approach combining various numbers of behavioral, neuroimaging and electrophysiological markers affects the performance of outcome predictions. We analyzed data...

In the search for EEG markers of human consciousness, alpha power has long been considered a reliable marker which is fundamental for the assessment of unresponsive patients from all etiologies. However, recent evidence questioned the role of alpha power as a marker of consciousness and proposed the spectral exponent and spatial gradient as more ro...

Mate Marote is an open-access cognitive training software aimed at children between 4 and 8 years old. It consists of a set of computerized games specifically tailored to train and evaluate Executive Functions (EF), a class of processes critical for purposeful, goal-directed behavior, including working memory, planning, flexibility, and inhibitory...

Does being awake mean being conscious? This study investigates Mind Blanking (MB), characterized by an “emptiness of mind”, comparing it with Mind Wandering (MW) and On-task (ON) states. Using a sustained attention task and electroencephalogram monitoring on 26 participants, behavioral and neurophysiological signatures of MB were examined. MB exhib...

Disorders of consciousness (DoC) are a challenging and complex group of neurological conditions characterised by absent or impaired awareness. The current range of therapeutic options for DoC patients is limited, offering few non-invasive pharmacological alternatives. This situation has sprung a growing interest in the development of novel treatmen...

It has been suggested that conscious experience is linked to the richness of brain state repertories, which change in response to environmental and internal stimuli. High-level sensory stimulation has been shown to alter local brain activity and induce neural synchrony across participants. However, the dynamic interplay of cognitive processes under...

Attention shapes our consciousness content and perception by increasing the probability of becoming aware and, or, better encode a selection of the incoming inner or outer sensory world. We designed a task to engage interoceptive and exteroceptive attention by orienting healthy participants to their heartbeats or auditory stimuli and investigated w...

Automated speech and language analysis (ASLA) is a promising approach for capturing early markers of neurodegenerative diseases. However, its potential remains underexploited in research and translational settings, partly due to the lack of a unified tool for data collection, encryption, processing, download, and visualization. Here we introduce th...

Executive functions like working memory, inhibitory control, and cognitive flexibility are a set of neurocognitive processes involved in reasoning, planning, and self-regulatory skills that allow goal-oriented behaviors. Mounting evidence supports the importance of these processes for educational success from early on. Executive functions can be im...

Background Disorders of consciousness (DoC) are severe neurological conditions in which consciousness is impaired to various degrees. They are caused by injury or malfunction of neural systems regulating arousal and awareness. Over the last decades, major efforts in improving and individualizing diagnostic and prognostic accuracy for patients affec...

Executive functions are a class of cognitive processes critical for purposeful goal-directed behavior. Cognitive training is the adequate stimulation of executive functions and has been extensively studied and applied for more than 20 years. However, there is still a lack of solid consensus in the scientific community about its potential to elicit...

The System Biology Markup Language (SBML) has been used to build numerous models of biological processes. Here we introduce a new method to translate SBML specifications of cellular models into formal specifications for analysis and simulation. To do so we define a generic biological model architecture that can be instantiated with different parame...

With the arrival of the pandemic in Argentina in March 2020, a working group of scientists from two institutes belonging to the Faculty of Exact and Natural Sciences of the University of Buenos Aires and CONICET, together with colleagues from different academic institutions in the country, decided to put forth our experience and knowledge in data s...

Embedded systems are increasingly used to control different devices ranging from toys, up to vehicles and spaceships. Each machine has special hardware designed to perform its tasks optimally, and there are constrains that emerge from the relation between hardware, embedded software and the environment. Discrete-Event Modeling of Embedded Systems (...

Embedded systems are increasingly used to control different devices ranging from toys, up to vehicles and spaceships. Each machine has special hardware designed to perform its tasks optimally, and there are constrains that emerge from the relation between hardware, embedded software and the environment. Discrete-Event Modeling of Embedded Systems (...

Modeling allows us to focus on the important components of a system under study, leaving aside the non-meaningful information. To study metabolic networks, we need to create a new model of the phenomena in order to start the simulations. Here, we propose a method for automating modeling and simulation of biological cell processes using DEVS. We hav...