Lana Abou-Zeid- PhD
- PostDoc Position at Ghent University
Lana Abou-Zeid
- PhD
- PostDoc Position at Ghent University
About
9
Publications
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23
Citations
Introduction
Current institution
Education
October 2018 - January 2022
Publications
Publications (9)
Mercury (Hg) is a globally significant pollutant, which is particularly concerning due to its ability to undergo long-range atmospheric transport and its bioaccumulation and biomagnification in marine ecosystems, even in remote regions like Antarctica. This study explores the biogeochemical cycling of Hg in the marine coastal environment of Terra N...
This study presents the development, validation and use of an approach for precise and accurate cadmium (Cd) isotopic analysis at low concentration levels using multi-collector inductively coupled plasma mass spectrometry...
In the field of nuclear toxicology, the knowledge of the interaction of actinides (An) with biomolecules is of prime concern in order to elucidate their toxicity mechanism and to further develop selective decorporating agents. In this work, we demonstrated the great potential of hydrophilic interaction chromatography (HILIC) to separate polar thori...
High-precision determination of the isotopic composition of mercury (Hg) is of paramount importance for unraveling its biogeochemical cycle and for identifying the origin of Hg in environmental compartments. Cold vapor...
A cyclic tetra-phosphorylated biomimetic peptide (pS1368) has been proposed as a promising starting structure to design a decorporating agent of uranyl (UO22+) due to its affinity being similar to that of osteopontin (OPN), a target UO22+ protein in vivo. The determination of this peptide’s selectivity towards UO22+ in the presence of competing end...
Several proteins have been identified in the past decades as targets of uranyl (UO22+) in vivo. However, the molecular interactions responsible for this affinity are still poorly known which requires the identification of the UO22+ coordination sites in these proteins. Biomimetic peptides are efficient chemical tools to characterize these sites. In...
L'objectif de ce travail a consisté à développer une méthode analytique pour déterminer à pH physiologique l'échelle d'affinité de peptides biomimétiques pour l'uranyle (UO22+), et leur sélectivité envers cet élément en présence de cations endogènes (Ca2+, Cu2+, Zn2+) en une étape unique. Cette approche est essentielle pour mieux comprendre les méc...
Peptides are efficient models used in different fields such as toxicology to study the interactions of several contaminants at the molecular scale, requiring the development of bio-analytical strategies. In this context, Hydrophilic interaction liquid chromatography (HILIC) coupled to electrospray ionization mass spectrometry (ESI-MS) was used to s...
