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Introduction
Current institution
Publications
Publications (14)
PURPOSE
To aid personalized treatment selection, we developed a predictive model for acute rectal toxicity in patients with prostate cancer undergoing radiotherapy with photons and protons.
MATERIALS AND METHODS
We analyzed a prospective multi-institutional cohort of 278 patients treated from 2012 to 2023 across 10 centers. Dosimetric and nondosim...
Simple Summary
Radiation therapy is an effective treatment for stage IIA and select stage IIB testicular seminoma patients. However, given the young age and long life expectancy of these patients, there are concerns about the risk of secondary cancers from radiation therapy. This study assessed the expected differences in secondary cancer risk for...
Purpose/Objective(s)
Radiation therapy to the para-aortic and iliac lymph nodes is an effective treatment for stage IIA and appropriately selected stage IIB seminoma patients. However, there are concerns for serious late complications, particularly an increased risk of secondary cancers due to the large areas of normal tissue irradiated. The purpos...
Purpose
Conventional rectal spacers (nonI-SPs) are low-contrast on CT, often necessitating an MRI for accurate delineation. A new formulation of spacers (I-SPs) incorporates iodine to improve radiopacity and CT visualization. We characterized placement, stability, and plan quality of I-SPs compared to nonI-SPs.
Methods
N=50 intact prostate cancer...
Cancer patients undergoing therapeutic radiation routinely develop injury of the adjacent gastrointestinal (GI) tract mucosa due to treatment. To reduce radiation dose to critical GI structures including the rectum and oral mucosa, 3D‐printed GI radioprotective devices composed of high‐Z materials are generated from patient CT scans. In a radiation...
We present an open-source platform to aid medical dosimetrists in preventing collisions between gantry head and patient or couch during photon or particle beam therapy treatment planning. This generic framework uses the native scripting interface of the particular planning software to import STL files of the treatment machine elements. These are vi...
Purpose: We present an open-source RayStation script to aid medical dosimetrists in preventing collisions between gantry head and patient or couch during photon or particle beam therapy treatment planning. Methods: STL files of the treatment room elements are imported in RayStation and visualized in 3D together with the contoured or scanned patient...
Purpose
Patients with Her2-positive breast cancer treated with trastuzumab have higher rates of cardiotoxicity (CT). Left-breast radiation might increase the risk for CT from cardiac exposure to radiation. The goal of our study is to evaluate the contribution of radiotherapy (RT) in the development of CT in breast cancer patients receiving trastuzu...
Purpose
To assess the safety and efficacy of administering liver re-irradiation to patients with primary liver tumors or liver metastasis.
Methods and Materials
49 patients (with 64 individual tumors) who received liver re-irradiation at our institution between 6/2008 and 12/2016 were identified for retrospective review. Patients were treated to t...
This study evaluates the implementation of volumetric‐modulated arc therapy (VMAT) using multicriteria optimization (MCO) in the RayStation treatment planning system (TPS) for complex sites, namely extremity and body sarcoma. The VMAT‐MCO algorithm implemented in RayStation is newly developed and requires an integrated, comprehensive analysis of pl...