Kusum de Abrew

Kusum de Abrew
University of Colombo · Department of Pharmacology Faculty of Medicine, Colombo

About

33
Publications
2,583
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
116
Citations
Introduction

Publications

Publications (33)
Article
Full-text available
Abstract Background Insulin therapy is essential for type 1 diabetes. While a reasonable glycemic control prevents complications, inadvertent intramuscular (IM) insulin injection results in hypoglycemia and fluctuations of blood glucose levels. Objective To assess the subcutaneous thickness (SCt) at the potential insulin injection sites, in order...
Article
Full-text available
Background Insulin therapy is essential for type 1 diabetes. While a reasonable glycemic control prevents complications, inadvertent intramuscular (IM) insulin injection results in hypoglycemia and fluctuations of blood glucose levels. Objective To assess the subcutaneous thickness (SCt) at the potential insulin injection sites, in order to determ...
Article
Full-text available
Background Management of epilepsy during pregnancy in a resource-limited setting (RLS) is challenging. This study aimed to assess obstetric outcomes and effects on babies of women with epilepsy (WWE) exposed to Anti-epileptic drugs (AEDs) compared to non-exposed controls in a RLS. Methods Pregnant WWE were recruited from antenatal and neurology cli...
Poster
Full-text available
Study population= 131 children (2-13 years): Study setting= Lady Ridgeway Hospital Colombo: Sites of measurements= bilateral mid-arms, anterior abdomen and mid-thighs, with and without a skin fold by ultrasonography. •Those with a distance from skin surface to muscle less than 15mm or 5mm were considered as having IM risk in the insulin injection s...
Conference Paper
Bioequivalence studies conducted in healthy volunteers are the usually accepted method to determine the therapeutic equivalence of two drug products. As these in vivo bioequivalence studies are time consuming and expensive to conduct, major regulatory authorities now accept biowaiver studies, using in vitro dissolution testing, for selected drugs b...
Article
Full-text available
Walking barefoot is common in poorer developing countries which have large rural populations. Although high rates of foot injury could be expected among those who walk barefoot, walking barefoot as a risk factor for diabetic foot disease is rarely documented in the literature. Two preliminary clinical studies were undertaken to investigate whether...
Article
To audit the structure, process and outcome of care. The diabetic clinic, National of Hospital Sri Lanka (NHSL). A previously validated MCQ paper of 10 questions which assessed knowledge of diabetes on insulin therapy, dietary management, management during acute illness and management of emergencies was administered to all patients. The function of...
Article
Improved glycaemic control is possible with the use of multiple injections of premixed insulin. These are expensive, and not available in state hospitals. To study the cost, patient acceptance and efficacy of a patient mixed and administered combination of soluble and lente (biphasic) insulin administered twice a day. A cohort of 25 patients with p...
Conference Paper
Full-text available
The study was to investigate the influence of age on glomerular filtration rate (GFR) and the effect of age adjustment of GFR on the prevalence of hyperfiltration in newly diagnosed non-insulin dependent diabetes mellitus (NIDDM) subjects. 157 previously untreated normotensive non-proteinuric NIDDM patients, mean (SD) age 51.7 (10.7) years and 82 h...
Article
Organophosphates are the most common group of chemicals involved in poisoning in Sri Lanka. Usually, poisoning is by ingestion for suicidal purposes, although accidental poisoning is not uncommon. Poisoning due to absorption through intact or damaged skin is rare. A 32-year-old man was admitted to a peripheral hospital following assault with a 100-...

Network

Cited By