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Kumaaran Subramanian

Kumaaran Subramanian

Ph.D.,

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58
Publications
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502
Citations

Publications

Publications (58)
Article
Full-text available
Natural colorants have emanated as a significant substitute to highly toxic synthetic dyes. The present study highlights the dyeing efficiency of violet pigment produced from Chromobacterium violaceum PDF23. A halophilic bacterium C. violaceum PDF23 produce violet pigments were isolated from the Great Salt Lake situated in Chennai, India. Based on...
Article
Full-text available
Streptomyces is amongst the most amenable genera for biotechnological applications, and it is extensively used as a scaffold for drug development. One of the most effective therapeutic applications in the treatment of cancer is targeted therapy. Small molecule therapy is one of them, and it has gotten a lot of attention recently. Streptomyces deriv...
Article
Full-text available
Mosquitoes are the most critical group of insects in the context of public health, since they transmit key parasites and pathogens, causing millions of deaths annually. Aedes albopictus is an important invasive mosquito vector of dengue fever across urban and semiurban areas of India. In this study, we biofabricated silver nanoparticles (AgNPs) usi...
Article
Full-text available
Abstract Hydrogel refers to a three-dimensional cross-linked polymeric network made of synthetic or natural polymers that can hold water in its porous structure. The inclusion of hydrophilic groups in the polymer chains, such as amino, carboxyl, and hydroxyl groups, contributes to the hydrogel’s water-holding ability. At physiological temperature a...
Article
Full-text available
Biowaste originating from aquaculture sector represents a potential feedstock to produce value-added substances and materials like chitin and chitosan. They are the long chain polymers of N-acetylglucosamine polymers with huge industrial and biomedical significance. Chitin has long been recognized as a useful biomaterial for drug delivery and neuro...
Article
Full-text available
Abstract Marine wastes pose a great threat to the ecosystem leading to severe environmental hazards and health issues particularly the shellfish wastes. The shellfish waste which contains half of the amount of chitin can be efficiently transformed into useful products. Various approaches for the hydrolysis of chitin like physical, chemical, and enz...
Article
Baseline assessments of marine microbial studies are very limited around ecologically sensitive areas of the Nuclear Power Plant (NPP) site with respect to their occurrence, distribution, role in adaptation, and their potential remediation process. The distribution and diversity of marine microbes are largely dependent on the physicochemical parame...
Article
Full-text available
The cultural microbiomes of 27 bacteria colonies were isolated from Mugil cephalus for analysis of the antibacterial and antagonistic activities. A potent probiotic bacterium was characterized using16S r RNA sequencing. The potent strain was added to fish diet to perform the challenge test and to study the growth and immunological parameter. The ex...
Article
Full-text available
Infectious disease-causing pathogenic microorganisms grow rapidly within quorum sensing mediated biofilms. Attempts are made to restrict quorum sensing in pathogens, and the formation of biofilms has paved the way for the identification of bioactive phytochemicals. Anti-QS compounds have been proven to reduce bacterial pathogenicity in the past. Me...
Article
The influence of fossil fuels on the environment focused on the development of new technology on biofuels. In this situation, lignocellulolytic hydrolysis enzymes such as Cellobiohydrolase, β-Glucosidase, Endoglucanase, cellulase and xylanase have broad applications in the biofuel production. The Trichoderma have used for the production of cellulas...
Article
The objective of this study was to develop nanobiomaterial containing silver nanoparticles (AgNPs) for wound healing. AgNPs were synthesized using Saussurea lappa (Sl) aqueous root extract as reducing agent and were characterized physico-chemically using UV-vis spectral studies, XRD, FESEM, TEM, FTIR spectral analysis, DLS, and TG-DSC. Sl AgNPs pro...
Article
The Trichoderma has been extensively used to degrade the xenobiotics. In the present study, thirty-nine open reading frames of cytochrome P450 genes from T. atroviride T23 genome was cloned and it was found to be distributed in 29 families under 21 clades. Among them, 21 cytochrome P450 genes were involved in the degradation of xenobiotics. The qua...
Article
Full-text available
Background. The direct or indirect effect of chemicals on the nervous system of humans or animals is referred to as neurotoxicity. Trimethyltin chloride (TMT) intoxication causes behavioral and cognitive deficiencies in humans and experimental animals. TMT has long been used as a model toxicant in the study of central nervous system (CNS) toxicity....
Chapter
DNA is referred to as the basic blueprint of life, but the implementation of the genetic plan is carried out by the activities of proteins. Hence, the biological diversity that is noticed in nature is therefore protein-based, and protein-level modifications pave way for the natural selection. Proteomics is the study of the proteome. The proteome is...
Article
Globally, the disposal of shellfishery waste is a major challenge and causes a risk to the coastal region. For potential development in aquaculture, the use of safe supplements to improve fish production and health is important. Chitosan (CS) used as feed additives for several fish species that enhanced production and immunity. The present study wa...
Article
Global warming in ocean ecosystems alters temperature, acidification, oxygen content, circulation, stratification, and nutrient inputs. Microorganisms play a dominant role in global biogeochemical cycles crucial for a planet’s sustainability. Since microbial communities are highly dependent on the temperature factor, fluctuations in the same will l...
Article
A comparative study of the accumulation of Reactive Red 11 (RR11) and Acid Green 1 (AG1) dyes using live yeast culture Pichia pastoris was investigated. The changes in inoculum volume, pH, initial dye concentration and the incubation temperature were studied. The maximum percentage of color removal efficiency, dye uptake capacity and bioaccumulatio...
Preprint
Full-text available
For the yeast population and diversity marine habitats are the least explored niches. The aim of the present study is to create a comprehensive DNA barcode library for marine derived yeast species. As we sequenced the ITS gene for 1017 isolates belonging to 157 marine derived yeast species in 55 genera, 28 families, 14 orders, 8 classes of 2 Phyla...
Article
Cyanobacteria are rich sources of structurally novel and biologically active metabolites with antibacterial, antiviral, antifungal, and anticancer activities. The present study aimed to evaluate the antimicrobial, antioxidant, and toxicity potential of freshwater filamentous cyanobacterial species isolated from a freshwater source in Kancheepuram d...
Article
Full-text available
Marine pollution is a significant issue in recent decades, with the increase in industries and their waste harming the environment and ecosystems. Notably, the rise in shellfish industries contributes to tons of shellfish waste composed of up to 58% chitin. Chitin, the second most ample polymer next to cellulose, is insoluble and resistant to degra...
Data
DNA ITS barcodes of 161 species of marine yeast collected along the Indian coast.
Article
In the present study, we synthesis nanoparticles using biosynthesis methods because of the eco-friendly approach. Gold nanoparticles were synthesized using extracellular metabolites of marine bacteria (Rastrelliger kanagurta, Selachimorpha sp., and Panna microdon). After the synthesis gold nanoparticles checked their antibacterial and antimycobacte...
Article
In this present study, selenium reducing bacteria were isolated from fresh water pond. The cell free supernatant from B2 strain was found to effectively reduce sodium selenite and was identified as Bacillus sp. Based on 16S r RNA sequencing. The selenium nanoparticles (Se NPs) synthesised using Bacillus sp B2 were characterised by UV- spec, XRD, FT...
Article
Taxol is a member of the taxane family of chemotherapy drugs, which includes cabazitaxel and docetaxel that have a promising role as anti-cancer drugs for specific human cancers. Hence, in order to meet the requirement, an alternative source for Taxol production, such as filamentous fungi is needed. In this study, a different endophytic fungus was...
Article
Glioma is the prime cause of cancer allied mortality in adolescent people and it accounts about 80% of all malignant tumours. Eugenol is a major bioactive constituent present in the essential oils with numerous pharmacological benefits including nueroprotective activity. The major drawback of eugenol is its extreme volatile property and oxygen sens...
Preprint
Full-text available
The present work aims to prepare magnesium aluminate nanoparticles (MgAl 2 O 4 NPs) using aluminum isopropoxide and magnesium ethoxide by hydrolysis reaction and to investigate them as new adsorbent materials for the extraction and clean-up of dimethomorph pesticide from tap water. The MgAl 2 O 4 NPs were characterized by X-ray powder diffraction (...
Article
Full-text available
Over the past decades, the feather waste degradation is one of the emerging problems due to the enormous wastes generated from poultry farms. In addition to poultry farms, the leather and wool industries are frequently producing million tons of keratin waste that have a negative impact on the environment. It emphasizes the critical need for researc...
Article
Full-text available
The present investigation had made to synthesis of silica nanoparticle (SiNp) from Bambusa vulgaris leaves (BVL) ash by using sol-gel technique and it was utilized for the removal of Cadmium (Cd) and Congo red (CR) in aqueous solutions. Further, the synthesized adsorbent was characterized using instrumental techniques such as XRD, FTIR, FESEM–EDS m...
Article
Full-text available
Bacterial diversity studies in hypersaline soil often yield novel organisms and contribute to our understanding of this extreme environment. Soil from Mad Boon is previously uncharacterized, with dense mangrove forest in one side and hypersaline soil in another side of backwater located in Southeast coast of Tamil Nadu, India. We surveyed to charac...
Article
Full-text available
Objective: In this study, the phytosynthesis of silver nanoparticles (AgNPs) using leaf extracts of Hygrophila auriculata (HA) and their biological activities was investigated.Methods: The synthesis of AgNPs was done by using the green synthetic method and analyzed by UV-Visible spectroscopy, X-ray diffraction (XRD), fourier transform infrared spec...
Article
Full-text available
The increased emergence of drug resistant microbes creates a major challenge to the scientific community for successful development of effective therapeutics. The antimicrobial activities of silver ions are well known, but limited information is available on the effects of green silver-nanoparticles (AgNPs) on human pathogens. In this report, a sim...
Article
Bacterial diversity studies in hypersaline soil often yield novel organisms and contribute to our understanding of this extreme environment. Soil from Mad Boon is previously uncharacterized, with dense mangrove forest in one side and hypersaline soil in another side of backwater located in Southeast coast of Tamil Nadu, India. We surveyed to charac...
Article
Full-text available
Objective: To focus on the growth rate and feed utilization of fish by using trash fish feeds supplement with marine seaweeds. Methods: Selected seaweed was extracted using hot-water and its extract was mixed with trash fish feed at different concentrations (0.5%, 1% and 2% for 1-30 days) and the nonspecific immune response in fish was studied and...
Technical Report
Full-text available
Bacillus flexus strain FDB3 16S ribosomal RNA gene, partial sequence (KM091675)
Technical Report
Full-text available
Bacillus cereus strain SSASC03 16S ribosomal RNA gene, partial sequence
Article
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Objective: To isolate bioactive molecules from marine seaweeds and check the antimicrobial activity against the fish pathogenic bacteria. Methods: Fresh marine seaweeds Gracilaria edulis, Kappaphycus spicifera, Sargassum wightii (S. wightii) were collected. Each seaweed was extracted with different solvents. In the study, test pathogens were collec...
Article
Full-text available
Objective: To analyse experimental infection and immune system of shrimp (Penaeus monodon) against V. furnissii. Methods: Experimental animals were collected and accumulated by maintaining specific temperature, pH and salinity to avoid mortality. Shrimps were experimentally infected with V. furnissii and their immune responses were monitored. After...
Conference Paper
Full-text available
The keratinous waste largely comprising of the insoluble structural protein “keratin” is increasingly accumulating in the environment mainly in form of feathers. Disulphide and hydrogen bonds makes keratin stable protein resistance to proteolytic hydrolysis. Feather, contains over 90% of crude protein in the form of keratin. Worldwide commercial po...
Article
Full-text available
The properties of silver nanoparticles are attractive and beneficial to the aquaculture industry. The major methods used for silver nanoparticle synthesis are the physical and chemical methods. The problem with the chemical and physical methods is that the synthesis is expensive and can also have toxic substances absorbed onto them. To overcome thi...
Article
Full-text available
Objective: Fresh marine seaweeds Gracilaria edulis, Gracillaria verrcosa, Acanthospora spicifera, Ulva facita, Ulva lacta (U. lacta), Kappaphycus spicifera, Sargassum ilicifolium, Sargassum wightii (S. wightii), Padina tetramatica and Padina gymonospora were collected from Mandapam (Rameshwaram, Tamil Nadu) of South East coast of India and were scr...
Article
Aquaculture is the world's fastest growing food production sector. However, fish culture is currently suffering from serious losses due to infectious diseases. The use of antimicrobial drugs, pesticides and disinfectant in aquaculture disease prevention and growth promotion has led to the evolution of resistant strains of bacteria. Thus, the resear...
Article
Full-text available
Objective At present scenario need the potential medical application enzymes and control the major clinical bacterial pathogens produce infections in humans. In this mind isolate and characterization of chitinase and antibacterial compounds from streptomyces.Methods The actinobacterial strains isolated from crab and shrimp shells disposable area (P...
Article
Full-text available
Objective To evaluate the in vitro antibacterial activity of various solvent extracts of South Indian traditional medicinal plants Ocimum sanctum, Ocimum gratissimum, Aegle marmelos, and Adhatoda vasica leaves against clinical pathogens of human origin.Methods The antimicrobial activity of different solvents crude extract of four medicinal plants u...
Article
Full-text available
To isolate antibacterial potential of sponge endosymbiotic bacteria from marine sponges at Lakshadweep archipelago. Also to identify the potent bacteria by 16s rDNA sequencing and determine the antibacterial activity against clinical pathogens by MIC. Sponge samples was collected from sub-tidal habitats at Kavaratti Island and identified. The endos...
Article
Full-text available
Objective: To determine the prevalence and antibiotic resistance of Escherichia coli (E. coli), in seafood obtained from Cuddalore and Parangipettai fish landing centres. Also, to identify the susceptibility of E. coli against predominant seaweeds red alga Kappaphycus alvarezii (K. alvarezii) and brown alga Padina boergessenii (P. boergessenii) ext...
Article
Full-text available
coli), in seafood obtained from Cuddalore and Parangipettai fish landing centres. Also, to identify the susceptibility of E. coli against predominant seaweeds red alga Kappaphycus alvarezii (K. alvarezii) and brown alga Padina boergessenii (P. boergessenii) extracts as sulfated polysaccharides and polyphenols respectively. Methods: A total of 48 sa...

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Projects

Projects (4)
Project
To barcode Marine yeast occurring along the Indian coastal region
Project
To achieve potential lead compounds