Kuan Shiong Khoo

Kuan Shiong Khoo
Yuan Ze University · Department of Chemical Engineering & Materials Science

Doctor of Philosophy (PhD) in Chemical and Environmental Engineering
Drop me an email for research collaboration: kuanshiong.khoo@hotmail.com or kuanshiong.khoo@saturn.yzu.edu.tw

About

136
Publications
35,058
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2,721
Citations
Citations since 2016
135 Research Items
2670 Citations
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Introduction
ChM. Dr. Kuan Shiong Khoo research focuses on the downstream processing of bioactive compounds such as proteins, lipids and carotenoids (i.e. astaxanthin, lutein and fucoxanthin) from microalgae using various extraction technologies such as liquid biphasic system, assisted-liquid biphasic system and ionic liquids technologies.

Publications

Publications (136)
Article
Aviation industry has a vital role in the economic growth and social development of the world. But, it shows negative impacts on the environment and thus this industry is looking for sustainable and clean fuel. Hydrogen energy is trusted as a promising fuel in the aviation industry, owing to the remarkable advantages. Different techniques, driven b...
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The incredible growth of the duckweed (DW) in the water ecosystem causes severe environmental problems and reduces biodiversity. Harvesting and valorization of such plants represents a challenge due to its richness with organics. Hydrogen productivity (HP) from dark fermentation of delignified duckweed (DDW) is the main objective of current researc...
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Macroalgae, with short growth cycles, and high CO2 fixation capacity, are third-generation biomass mainstays that play an essential role as a global carbon sink. Macroalgal biochar plays a crucial role in soil improvement, pollutant adsorption, electrodes, and capacitors, and it has already contributed to both ecological and economic fields. Howeve...
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Microplastics (size <5 mm) debris are environmentally persistent pollutants that severely affect terrestrial ecosystems by promoting the loss of soil fertility, and microbiome. The adverse effect of microplastics on the terrestrial ecosystem led to changes in physic-chemical and biological characteristics of soil resulting changes in nutrient cycli...
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The identification of microalgae species is an important tool in scientific research and commercial application to prevent harmful algae blooms (HABs) and recognizing potential microalgae strains for the bioaccumulation of valuable bioactive ingredients. The aim of this study is to incorporate rapid, high-accuracy, reliable, low-cost, simple, and s...
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This study aimed to decrease the production cost and increase tilapia yield with a feeding regime. The trial was divided into four treatments with three replications followed by the feeding frequency in monosex male Nile tilapia with an average initial weight of 17.86–18.40 g/fish cultured on a net cage in the earth pond for three months. Fish fed...
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Water usage increased alongside its competitiveness due to its finite amount. Yet, many industries still rely on this finite resource thus recalling the need to recirculate their water for production. Circular bioeconomy is presently the new approach emphasizing on the ‘end-of-life’ concept with reusing, recycling, and recovering materials. Microal...
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Catalytic reactions in producing biofuels often face issues such as low product yield, low selectivity to preferred products and serious environmental issues which leads to the exploration of green technologies. Microwave technology is one of the green technologies that is widely applied in the field such as medical, food, signal processing or navi...
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With the rapid development of the economy and productivity, an increasing number of citizens are not only concerned about the nutritional value of algae as a potential new food resource but are also, in particular, paying more attention to the safety of its consumption. Many studies and reports pointed out that analyzing and solving seaweed food sa...
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Microalgae are autotrophic microorganisms that exist in a variety of environments, including marine, freshwater, and soil. Microalgae create organic molecules through natural photosynthesis. In recent years, the increased socioeconomic awareness has shifted to renewable and algae-based bioenergy due to the negative repercussions of excessive oil co...
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The ever-increasing quantity of greenhouse gases in the atmosphere can be attributed to the rapid increase in the world population as well as the expansion of globalization. Hence, achieving carbon neutrality by 2050 stands as a challenging task to accomplish. Global industrialization had necessitated the need to enhance the current production syst...
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Membrane distillation (MD) is a thermally driven technology applied in desalination and water reuse with utilisation of sustainable energy. However, algal organic matter (AOM) could foul membrane critically and plague MD's long-term operational stability. In this study, the soluble extracellular polymeric substance (sEPS) and intracellular organic...
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Lipoxyg­­enases have proven to be a potential biocatalyst for various industrial applications. However, low catalytic activity, low thermostability, and narrow range of pH stability largely limit its application. Here, a lipoxygenase (LOX) gene from Enterovibrio norvegicus DSM 15893 (EnLOX) was cloned and expressed i­n Escherichia coli BL21 (DE3)....
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This paper examines the potential of suitable second-generation feedstocks for sustainable aviation fuel production, theoretically based on fatty acid-based fuel properties. The fatty acid composition of 38 s-generation feedstocks was collected from the literature. The fuel properties of these feedstocks were then calculated using empirical formula...
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Distillation has relatively low thermodynamic efficiency, so it is a prime target for process intensification studies. The current research aims to study exergy losses in various heat-integrated distillation columns. A conventional industrial-scale i-butane/n-butane fractionator has been selected as a case study for the comparison of the performanc...
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Currently, increasing energy demand due to overpopulation has provoked an urge for renewable energy sources like biodiesel. Biodiesel production from non-edible seed oils provides striking solution to the problems associated with the energy crisis. In this study, the potential of Citrus medica as a novel and non-edible seed oil (33% w/w) producing...
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Palm oil mill effluent (POME) is defined as the wastewater that contains high concentrations of organics, nutrients and oil and grease generated from the production process of palm oil. Therefore, proper discharge and management of POME is important to avoid deleterious impact on the environment. In fact, solid waste generation is a precursor for i...
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Pharmaceutical compounds being able to alter, retard, and enhance metabolism has gained attention in recent time as emerging pollutant. However, hospitals which are part of every urban landscape have yet to gain attention in terms of its hospital wastewater treatment to inhibit pharmaceutical compounds from reaching environment. Hence this study ev...
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Biosensors are devices that convert biological responses into electrical signals. Biosensors can be utilised in a variety of applications, including environmental and water quality monitoring, as well as medical applications. Thus, researchers have been working on them and experimenting with new nanofabrication techniques. Nanomaterials like graphe...
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Bisphenol-A (BPA) is a type of Endocrine Disrupting Compound (EDC) that is being widely used in the production of polycarbonate and epoxy resins. Last few years, the human exposure to BPA has been extensively high due to continuous increment in Annual Growth Rate (AGR) of BPA global market. The presence and transportation of BPA in the environment...
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The effects of synthetic fertilizer and nutrient leaching are causing serious problems impacting soil function and its fertility. Mitigation of nutrient leaching and use of chemical fertilizer is crucial as fertile land adds up sustainability to climate changes. Biochar produced from agricultural bio-waste and municipal solid waste has been used fo...
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Contaminated soil containing toxic metals and metalloids is found everywhere globally. As a consequence of adsorption and precipitation reactions, metals are comparatively immobile in subsurface systems. Hence remediation techniques in such contaminated sites have targeted the solid phase sources of metals such as sludges, debris, contaminated soil...
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The extensive usage of synthetic fungicides against fungal diseases has caused adverse impacts on both human and agricultural crops. Therefore, the current study aims to establish a new bacterium 7WMA2, as a biocontrol agent to achieve better antifungal results. The strain 7WMA2 was isolated from marine sediment, displayed a broad spectrum of sever...
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An expeditious pace of expanding industrialization and urbanization is a global vulnerability which immediately requires utmost attention towards the replacement of prosaic petroleum-based polymer assimilation. Thus, greening the innovative route of microalgae derived biopolymers has attained significant interest as an improved and sustainable appr...
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Biomass valorization in converting biomass into value-added products and energy has gained researchers’ attention. In this study, valorization of oil palm empty fruit bunch (OPEFB) towards biofuels production was focused. Combination of deep eutectic solvent (DES) and ultrasonication was employed to pretreat the OPEFB. The pretreatment was conducte...
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There has been an urgent need to tackle global climate change and replace conventional fuels with alternatives from sustainable sources. This has led to the emergence of bioenergy sources like biofuels and biohydrogen extracted from microalgae biomass. Microalgae takes up carbon dioxide and absorbs sunlight, as part of its photosynthesis process, f...
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Soy isoflavone extracts are widely researched for their distinctive potential in contributing to various functional foods. The research work focuses on testing the toxicity of purified soy isoflavone extracts in mice models. With an agreement of the animal ethics, acute toxicity is firstly used to screen the effects of test compounds in mice for th...
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Short-chain olefins are the important feedstock for the chemical industries. The selection of a proper catalyst for oxidative dehydrogenation (ODH) reaction is critical. Here, the study summarized different catalysts by physicochemical techniques such as BET surface area, Raman spectroscopy, and temperature programmed reduction (TPR). The BET analy...
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Fossil fuels produce harmful gases that adversely affect the environment and human health. Although some sources of energy (e.g., solar, wind, and biofuels) are clean and renewable, substantial research is required to compete with fossil fuels. Several research studies are available on parabolic trough solar collectors, but process modeling and the...
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In recent days, the existence of several food colorants has an impact on human health issue that may induce major carcinogenic effects. Therefore, the removal of food colorants must be made in accordance with the necessity of health awareness in life. Photocatalyst treatment using semiconductors shows a promising way to solve these issues. In this...
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Population inflation has led to the unprecedented increase in urbanization, thus causing negative impacts on environmental sustainability. Recently, there is an upsurge in the number of restaurants due to the changing lifestyles of the people. There were 167,490 food and beverage establishments in 2015, representing an annual growth rate of 5.1% si...
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Ozone-based processes gained much attention in recent years. However, due to low oxidative stability and utilization rate, single ozonation process (SOP) is insufficient for complete mineralization of pollutants. As a result, the single ozonation process is performed in the presence of a catalyst, a process known as catalytic ozonation process (COP...
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As a promising strategy of free energy storage carrier, the mostly ammonia (NH3) is produced through the Haber-Bosch process, having extensive requirement of the energy along with the emission of greenhouse gases. However, as a potential Haber-Bosch replacement, the advancement in photo/electrocatalytic nitrogen reduction process (NRR) is being inv...
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The research and innovative strategies for large scale production and commercialization of algae based biodiesel still presents a need for analysis based on sustainability and quality check. In this study, the three key growth factors (nitrogen concentration, temperature and pH) were manipulated using the Box-Behnken design of the experiment, with...
Article
Renewable energy sources such as biomass have been proven to be one of the promising sustainable alternatives to fossil fuels. However, using biomass directly as a fuel is less attractive due to its high moisture content, poor grindability, low bulk density, and low energy density nature. Hence biomass can be converted into biochr to overcome these...
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The present study evaluated the potential of biodegrading the toxic synthetic dye malachite green (MG) by an enzymatic approach. Extracellular laccase derived a fungal strain Fusarium oxysporum HUIB02 was used in the direct biodegradation of MG. Time-course study showed that the crude laccase successfully removed ≥ 80% MG after 20 h of treatment. T...
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The composite materials based on graphitic carbon nitrides (g-C3N4) are remarkably better semiconductors, but the inherent photocatalytic performance in its generic synthesis form is not up to the mark. Eminence efforts have been made to improve its performance and photocatalytic efficiencies. Recently, extensive investigations have been performed...
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This review provides a quantitative description of the nano-adsorbent processing and its viability against wastewater detoxification by extracting heavy metal ions. The impact of nano-adsorbent functionalities on specific essential attributes such as the surface area, segregation, and adsorption capacity were comprehensively evaluated. A detailed a...
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ARTICLE INFO Handling editor Keywords: Groundwater pollution Industry Heavy metal Health risk assessment Water quality index Hazard quotient index ABSTRACT Groundwater is the second largest water source for daily consumption, only next to surface water resources. Groundwater has been extensively investigated for its pollution level in urban areas....
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Herbal nanoparticles (HNPs) were introduced as a novel generation of antimicrobial nanoparticles. But in the battle against superbugs we need nanostructures with boosted antimicrobial potency. So in the current experiment, for the first time a green approach was developed for the silver functionalization of HNPs which were fabricated from an antimi...
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Biomass gasification technology has an ancient and well-established background. The technology has widely been used to produce H 2 and syngas which is subsequently upgraded to obtain valuable biofuels, Fischer-Tropsch chemicals and used in combined heat and power (CHP) plants. Abatement of tar-related complexes with an improved hydrogen content and...
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The performances of autotrophic and heterotrophic metabolisms in Chlorella vulgaris were assessed from various photoperiod regimes for the sustainable microalgal biodiesel production. Accordingly, the cellular biomass growth and lipid content in relation to the organic nutrient removals from municipal wastewater medium were evaluated from the vario...
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Groundwater is the second largest water source for daily consumption, only next to surface water resources. Groundwater has been extensively investigated for its pollution level in urban areas. The groundwater quality assessments in industrial areas associated with every urban landscape are still lacking. This study was carried out in two industria...
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Contamination of paddy soils with arsenic (As) poses imminent threat to the environment and public health. This research work explored the effect of goethite-modified biochar (GMBC) on As immobilization in paddy soil and subsequent accumulation in rice grains. The results showed that the soil supplementation with GMBC significantly improved the bio...
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Production of indole-3-acetic acid (IAA) is well documented in various studies for the bacteria that inhabit the rhizosphere of plants, but with roots of wet rice, the outstandings have been not yet elucidated. This study began with the isolation of bacteria type strain Azospirillum sp. and developed the investigation to a screening of their abilit...
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Biosurfactant is one of the emerging compounds in the industrial sector that behaves similarly with their synthetic counterparts, as they can reduce surface and interfacial tension between two fluids. Their unique properties also enable biosurfactant molecules to be able to clump together to form micelles that can capture targeted molecules within...
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Background The current study was designed to calculate the approximate energy potential of combustible fraction shared in the overall domestic solid waste stream generated from Faisalabad, the 3rd largest city and an industrial hub of Pakistan through ASTM standards. Methods Characterization of samples were collected during the rainy season from J...
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Background Throughout the world, food wastage issues continue to plague almost every country. Multiple ideas and solutions have been conceived and are continuously being tested by scientists and government bodies to mitigate food waste management issues. Black Soldier Fly (BSF) rearing is an up-and-coming commodity because of its versatility and mu...
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The pulp and paper industry consumes enormous quality of freshwater, leading to wastewater. It must be treated to remove pollutants, particularly residual dyestuffs, before releasing them to water bodies to avoid adverse environmental effects. The traditional wastewater treatment methods used for the pulp and paper industry are less efficient in co...
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Electropermeabilization-assisted liquid biphasic flotation (LBF) system is an emerging extraction system facilitated by the adsorptive bubble separation and the electroporation in an aqueous two-phase medium. This integrative extraction system is well suited for the direct recovery of intracellular biocompounds from cells without the needs of discr...
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Agriculture farms such as crop, aquaculture and livestock have begun the implementation of Internet of Things (IoT) and artificial intelligence (AI) technology in improving their productivity and product quality. However, microalgae farming which requires precise monitoring, controlling and predicting the growth of microalgae biomass has yet to inc...
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The formation of gas hydrates is a major issue during the operation of oil and gas pipelines, because gas hydrates cause plugging, thereby disrupting the normal oil and gas flows. A solution is to inject gas hydrate inhibitors such as ionic liquids. Contrary to classical inhibitors, ionic liquids act both as thermodynamic inhibitors and hydrate inh...
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Rice straw residue management is still facing many problems worldwide. This study used two environmentally friendly methods to investigate the effects of rice straw burning activity on water-extracted carbohydrate content in long-term paddy soil. Soil samples were collected at a depth within 0–15 cm at the paddy field before and after burning rice...
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The litter of persistent organic pollutants (POPs) into the water streams and soil bodies via industrial effluents led to several adverse effects on the environment, health, and ecosystem. For the past decades, scientists have been paying efforts in the innovation and development of POPs removal from wastewater treatment. However, the conventional...
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From an industrial perspective, the exploitation of microalgae as protein source is of great economical and commercial interest due to several attractive characteristics. However, the protein extraction efficiency is limited by the multiple layers of rigid and thick cell walls that are enriched with recalcitrant structure of cellulose. Therefore, a...
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Lignocellulosic biomass has arisen as a solution to our energy and environmental challenges because it is rich in feedstock that can be converted to biofuels. Converting lignocellulosic biomass to sugar is a complicated system involved in the bioconversion process. There are indeed a variety of techniques that have been utilized in the bioconversio...
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This study was aimed to identify and optimize the culture conditions for gamma-aminobutyric acid (GABA) production by a lactic acid bacterium strain isolated from mam nem, a fermented fish sauce. Among the six isolates obtained from mam nem, the MN12 had the most potent GABA-producing capability. The strain was then identified to be Pedioccocus pen...
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The impact of different nitrogen sources on the microalga, Chlorella vulgaris, was studied in a newly developed microalgal-bacterial photobioreactor via a dual nutrient heterogeneity mode. The mechanisms of nitrogen transformation and valorisation were unveiled, and subsequently, optimized via dual nutrient heterogeneity feeding modes comprising of...
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Using solar energy to catalyse photo-driven processes to address the energy crisis and environmental pollution plays a role in the path to a sustainable society. Many oxide-based materials, especially perovskite oxides, have been widely investigated as catalysts for photocatalysis in energy and environment because of the low-cost and earth-abundant...
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This research work aims to fabricate an optimized up-scaled photobioreactor and extraction tank which incorporates the Internet of Things (IoT) for remote monitoring of selected parameters without being present in the lab as the industry is gradually moving towards the direction of remote operation. Several design factors were considered where mode...
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In hemodialysis process, membrane serves as a barrier between blood and the dialysate. The barrier when contacted by blood accompanied activation of coagulation, immunity, and cellular passageways. In the recent years, hemodialysis membrane's biocompatibility has become a issue which leads to reduce the performance during the separation process. In...
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Global demand for plastic materials has severely harm the environment and marine sea life. Therefore, bioplastics have emerged as an environmentally friendly alternative due to sustainability, minimal carbon footprint, less toxicity and high degradability. This review highlights the sustainable and environmentally friendly approach towards bioplast...
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MicroRNAs (miRNAs) are important non-coding, single-stranded RNAs possessing crucial regulating roles in human body. Therefore, miRNAs have received extensive attention from various disciplines as the aberrant expression of miRNAs are tightly related to different types of diseases. Furthermore, the exceptional stability of miRNAs has presented them...
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The present work investigates the proficiency of green silver oxide nanocatalyst synthesised from Monotheca buxifolia (Falc.) Dcne. leaves extract, and their application for biodiesel synthesis from novel Prunus bokhariensis seed oil (nonedible). The seed oil content of 55% and FFA content of 0.80 mg KOH/g were reported. Several analytical tools (E...
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One of the most significant chemical operations in the past century was the Haber-Bosch catalytic synthesis of ammonia, a fertilizer vital to human life. Many catalysts are developed for effective route of ammonia synthesis. The major challenges are to reduce temperature and pressure of process and to improve conversion of reactants produce green a...
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Microalgae is an autotrophic organism with fast growth, short reproduction cycle, and strong environmental adaptability. In recent years, microalgae and the bioactive ingredients extracted from microalgae are regarded as potential substitutes for raw materials in the pharmaceutical and the cosmetics industry. In this review, the characteristics and...
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Improper lignocellulosic wastes management causes severe environmental pollution and health damage. Conversion of such wastes particularly sugarcane bagasse (SCB) onto bioenergy is a sustainable approach due to a continuous depletion of conventional biofuels. The delignification of SCB is necessary to proceed for bio-genic H2 productivity by anaero...
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The paper evaluates the routes towards the fabrication and characterization of membranes using ZIF-62 metal organic framework (MOF) nano-hybrid dots for environmental remediation. Optimization of interaction of operating parameters over the rooted membrane is challenging issue. Subsequently, the interaction of operating parameters including tempera...
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Membrane technology and deep eutectic solvents (DESs) have demonstrated their efficient and alterable functionality against environmental pollutants in a cost-effective way. This research focuses on the surface tunning and interface engineering of DES using cetyltrimethylammonium bromide (CTAB) and acetic acid to immobilize on mesoporous silica MCM...
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The emerging growth of the electronic devices applications has arisen the serious problems of electromagnetic (EM) wave pollution which resulting in equipment malfunction. Therefore, polymer-based composites have been considered good candidates for better EMI shielding due to their significant characteristics including, higher flexibility, ultrathi...
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New pandemic infection of coronaviridae family virus spread to more than 210 countries with total infection of 1,136,851 and 62,955 (4.6%) deaths until 5th April 2020. Which stopped the regular cycle of humankind but the nature is consistently running. There is no micro molecule remedy found yet to restore the regular life of people. Hence, we deci...
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Renewable diesel as a potential sustainable energy source in future requires catalysts to convert the feedstocks into end products. Among various type of catalysts, bimetallic catalysts are widely applied in the renewable diesel production due to their unique catalytic properties and enhanced catalytic activities, which differ from their parent mon...
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The efforts have been made to review phyllosilicate derived (clay-based) heterogeneous catalysts for biodiesel production via lignocellulose derived feedstocks. These catalysts have many practical and potential applications in green catalysis. Phyllosilicate derived heterogeneous catalysts (modified via any of these techniques like acid activated c...
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Microalgae metabolites include biologically active compounds with therapeutic effects such as anticancer, anti-inflammatory and immunomodulation effects. One of the most recent focuses is on utilizing microalgae lipid-based biologically active compounds in food applications. However, most microalgae biological active compounds in their natural form...
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The final disposal of waste generated by human activities has been turned into a great challenge; until now, little attention has been paid to organic waste, particularly from the restaurant sector. This work describes the process of obtaining calcium carbonate contained in oyster and clam shells re-collected in seafood restaurants. The IR absorpti...