Kshetrimayum  Birla Singh

Kshetrimayum Birla Singh
Manipur University · Department of Life Sciences (Zoology)

M.Sc. Ph.D.

About

48
Publications
18,552
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332
Citations
Introduction
Kshetrimayum Birla Singh currently working at the Department of Zoology, Manipur University, Canchipur, India as Professor. His area of research interest is Metal metabolism, trace mineral nutrition, DNA polymorphism in diseases and Alternative medicines. His current project is 'Study on the effect of long term excessive Zn supplementation on gene expression of antioxidant enzymes in wistar rats and their F1 generation rats.'
Additional affiliations
August 2009 - October 2017
Mizoram University
Position
  • Study on the effect of long term excessive zinc supplementation on oxidative stress in wistar rat
Description
  • K.B Singh
October 2017 - March 2020
Sikkim University
Position
  • Head & Associate Professor
Description
  • Administrative, Teaching and Research

Publications

Publications (48)
Article
Full-text available
Despite their limited geographic extent, wetlands possess a remarkable capacity to sequester carbon from the atmosphere, storing it in vegetation, sediments, and phytoplankton. The hydrology of the water also exerts a significant influence on the vegetation of the wetland. To our knowledge, research on the relationship between water physicochemical...
Article
Full-text available
In the process of carbon sequestration, CO₂ present in the earth's atmosphere is captured and stored as part of the biological carbon cycle via photosynthesis to mitigate warming of earth and avert climate change. Now, it is crucial for the various community around the world to acknowledge alternative sinks for carbon beyond the traditional focus o...
Article
Full-text available
Bonnaya ruellioides (Colsm.) Spreng is an ethnomedicinal plant widely found in Manipur, a northeastern state of India and it belongs to the Linderniaceae family. The study aimed to evaluate the phytochemical content, trace metals, antioxidant and antimicrobial activity of this ethnomedicinal plant in various extracts including chloroform, petroleum...
Article
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In recent years, overexplorations of ore and the growth of industries are the prime factors in the release of heavy metals in environments. As a result, the food crops and water bodies are contaminated with metals which may have several adverse effects on the health of humans and other living species. These metals and metalloids, such as Zn, Cu, Mn...
Article
Full-text available
In recent years, zinc (Zn) has been extensively employed in agricultural and livestock practices, as well as in baby foods and multivitamin supplements, due to its perceived non-toxic nature and its ability to promote linear growth and body weight in consumers and consequently, its usage is increasing steadily. This study investigates the impact of...
Article
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The effects of chlorpyrifos, a frequently detected organophosphate in aquatic ecosystems, on biochemical (protein and glycogen) contents and oxidative enzyme activities (catalase and lipid peroxidation) in liver, muscle and gill tissues of three freshwater fish Trichogaster fasciata, Mystus vittatus and Heteropneustes fossilis were evaluated after...
Article
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Tangkhul tribes are main habitant of the Ukhrul district of Manipur, a north eastern state of India and popular for using the products of animal fauna in the folklore medicines for curing certain human ailments. To our knowledge, no investigation has been done on the essential fatty acids content in the animal products used in the traditional medic...
Article
Full-text available
North East India is well renowned for its rich biodiversity, and the locals there eat differently from those in other parts of the nation. Numerous people in this area considered insects delicacies and used them in their diets. Manipur is a relatively undiscovered region with limited research on the variety of its wildlife, particularly about insec...
Article
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This research examines rare and unexplored traditional waste food processing and fermentation methods. Processed waste foods as well as fermented foods represent an important segment of the most commonly consumed foodstuffs and the nutrient suppliers of the living populations across the world. Soibum, hawaijar, ngari, hentak, and yongchak are some...
Article
Over the past few decades, environmental contamination from the wastewater industry has gravely threatened the environment and public health. According to reports, thousands of different dyes and pigments are used in a range of industries around the world each year, producing more than 7 × 105 tonnes of synthetic dyes. Environmental contamination c...
Research
Full-text available
Snails, locally known as "Tharoi" are consumed as an authentic cuisine and form a major dietary component of the ethnic people of Manipur. To date, no study has been carried out on the essential elements content of the freshwater edible snails commonly consumed by the natives of Manipur. In this study, an analysis of essential major and trace eleme...
Article
Full-text available
Ethnozoology is an applied discipline that integrates both the basic and social sciences which observe the aspects of nature, socioeconomic, anthropological and historical aspects of the animal and human relationship exist in that community. Tangkhul Naga community of the Ukhrul district of Manipur have a rich heritage of using animal products in t...
Article
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Terminalia chebula Retz. (Fam. Combretaceae), locally called Manahei, is a well-known medicinal plant that grows wildly in Manipur, a Northeastern state of India. It is used as a mild laxative, an anti-inflammatory agent, and a remedy for piles, colds, and ulcers by ethnic communities of the state. The hydroalcoholic extract obtained from four frui...
Presentation
Zinc (Zn) is a trace element required for the efficient functioning of human and animal bodies in a variety of biological activities. However, overconsumption of this crucial micronutrient inhibits immune responses and increases the severity of illnesses in people and animals. The supplementation of pharmacological dosage of Zn in an otherwise Zn-a...
Article
Full-text available
Sikkim and Darjeeling Himalayan Regions are famous for organic farming. Vegetables and meats food stuffs are an important source of metals like Cu, Zn, Mn and Fe which have very important biological roles as they participate in many proteins structure and functions. The concentration of these elements in vegetables and meat food samples of Gangtok...
Article
Full-text available
The use of the zinc in various areas such as animal husbandry, agricultural techniques and multivitamin supplements has increased in recent decades and will increase over time. In this study, the impact of Zn overload for long period in the body, and their carry-over effect on the next generation is determined. Three groups of rats were fed on basa...
Article
Full-text available
Manipur lies in the north-eastern region of India under the Indo-Burma biodiversity hotspot having a rich variety of flora and fauna. Tangkhul tribes are main habitant of the Ukhrul district of Manipur and popular for using the products of animal fauna as traditional medicines for curing many human diseases. No study has been carried out so far on...
Article
Full-text available
Cyanobacteria have attracted the attention of researchers because of their promising role as primary and secondary metabolites in functional food and drug design. Due to an ever-increasing awareness of health and the use of natural products to avoid the onset of many chronic and lifestyle metabolic diseases, the global demand for the use of natural...
Poster
In spite of the impressive progress that has been made in the field of trace element nutrition in the past, the biological role and minimum requirement of trace elements are still hypothetical. Zinc (Zn) is a micronutrient and is used indiscriminately in agricultural and husbandry practices and also in baby foods and multivitamin supplements since...
Article
Full-text available
Proton induced X-ray emission (PIXE) and gas chromatography-mass spectroscopy (GC-MS) were used to detect elements as well as phytochemicals in the Centella asiatica and Elsholtzia communis having possible roles for cardio-protections. Elements namely K, Cl, Ca, Fe, Mn, Zn and Cu were present in varying concentration with notable concentration of K...
Chapter
Full-text available
Medicinal plants have been used by humans for centuries in folklore medicine. Medicinal plants are also incorporated into the historical medicine of virtually all human cultures. The present work discusses the elemental determination of elements in two medicinal plants Solanum nigrum linn and Spilanthes acmella by using energy dispersive X-ray fluo...
Chapter
Allium hookeri Thwaites and Clerodendrum colebrookianum are important medicinal plants widely used by the local people Mizoram to garnish cooking and as ingredients in cooking popular delicious dishes. Their leaves have also been used as a home remedy by the Mizo tribal community of Mizoram in their folklore medicine as a cardio-protective (mainly...
Poster
Sikkim is well known for its scenic beauty, immensely rich biological diversity manifested by diverse eco-climatic conditions and wide altitudinal variation and is a part of Indo Burma biodiversity hotspots of the world. Large cardamom is an important cash crop of Sikkim and about 3863 MT of large cardamom are produced annually in Sikkim. However,...
Article
Full-text available
The present study was aimed to study the ultra-structural numerical changes in the microvilli of intestinal mucosal epithelial cells (IMECs) after excessive Zn supplementation in wistar rats. In this study, three groups of rats were fed on an equicaloric sugar and fat rich semi-synthetic diet containing 20mg (control, group-I), 50mg (group-II) and...
Article
Full-text available
Protein tyrosine phosphatases are not considered to be metalloenzymes. Yet, they are inhibited by zinc cations and metal and non-metal oxyanions that are chemical analogues of phosphate, e.g. vanadate. Metal inhibition is generally not recognized as these enzymes are purified, supplied, and assayed with buffers containing chelating and reducing age...
Article
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There is high prevalence of urolithiasis in the natives of the North Eastern part of India and required urgent attention. The present study was conducted with an aim to assess the state of oxidative stress and antioxidant vitamins status in patients with urolithiasis from North Eastern Region of India as there is no clinical data to date in the pat...
Article
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A new paradigm in metallobiochemistry describes the activation of inactive metalloenzymes by metal ion removal. Protein tyrosine phosphatases (PTPs) do not seem to require a metal ion for enzymatic activity. However, both metal cations and metal anions modulate their enzymatic activity. One binding site is the phosphate binding site at the catalyti...
Article
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There is paucity of data in respect to elemental concentration in the foodstuffs consumed by the living population of North East Region of India. Thirteen elements (Ca, K, Cl, P, S, Fe, Mn, Zn, Cu, Se, Sr, Rb and Br) were detected by using versatile Energy Dispersive X-ray Fluorescence(ED-XRF) technique in eight selected leafy vegetable foodstuffs...
Article
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Diabetes Mellitus (DM) is a global health problem and increasing all over the world at an alarming rate that appears dramatic as to have been characterized as an epidemic. DM is a chronic metabolic and hormonal disorder and is characterized by increase in blood glucose level accompanied by other biochemical disturbances and clinical manifestation....
Article
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Metal ions played critical role in regulation of hypertension (HT) or blood pressure (BP). The physiological roles of metals commonly present in the diet in the etiology of HT need to be reviewed as recent survey on the metal status in the various vegetable and meat food stuffs commonly consumed by living population in India revealed an imbalance i...
Article
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Elements are required by human body and have various roles in biochemical functions mostly as catalyst for enzymatic activity in human body. Some trace elements are essential since they are inadequately or not at all synthesized by human body. The deiciency or excess of those essential trace elements may cause diseases and be deleterious to health....
Article
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Objective: To determine the trace elements content in the selected medicinal plants, namely, Eryngium foetidum L., Mimosa pudica L., Polygonum plebeium, and Prunus cerasoides D. Don traditionally used by the natives of the Mizoram, one of the north eastern states in India as their folklore medicines for curing skin diseases like eczema, leg and fi...
Article
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276 | P a g e F e b r u a r y 0 6 , 2 0 1 4 ABSTRACT Aim: To study antioxidant and free radical scavenging potential of Allium hookeri methanol roots extract (MREAH) using different in vitro models Materials and Methods: Different in vitro models such as lipid peroxidation, metal chelation and reducing potential assays were used to determine antiox...
Article
Full-text available
Urolithiasis is a condition in which stones are formed in the urinary tract and considered to be one of the most common urological disorders, longstanding medical illnesses and common public health problems. People in many parts of the world including north eastern states of India are now suffering from the stone diseases. Urinary stone is formed u...
Article
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A modified poultry egg (Indian Patent Application No. 2264/Del-2005) and chick muscle enriched with optimum minerals, vitamin E and omega-3 fatty acid were developed and its efficacy was studied on oxidative stress of Type-2 diabetes mellitus induced male wistar rats. In this study, two groups of rats were fed on semi-synthetic diet containing 20 m...
Conference Paper
Full-text available
Abstract. Our previous studies revealed that excessive Zn supplementation in the diet trigger the onset of obesity in rats. Since oxidative stress is highly correlated with the metabolic states including obesity and related diseases, the need to study arises to confirm whether the onset of obesity by excess Zn in diet is associated with oxidative s...
Article
Full-text available
The use of Zn as micronutrient in husbandry and agriculture practices and also in baby foods and multivitamin supplements have been increased during the last two decades. However, the effect of long term increasing Zn load on the oxi-dative stress in the body has not been worked so far. The supplementation of pharmacological dosage of Zn in otherwi...
Conference Paper
Full-text available
The aim of this study was to determine the levels of heavy metals (Pb and Cd) and trace minerals (Zn, Cu, Se and Mn) in the samples of vegetables and meat foodstuffs commonly consumed by Mizo population of Aizawl by using Atomic Absorption Spectrophotometer (AAS). The heavy metals detected in the samples of vegetable foodstuffs ranged from 0.013 to...
Article
Full-text available
Vegetables and meat foodstuffs form important sources of vitamins, proteins and essential minerals for human nutrition. Zn, Cu, and Mn concentrations were determined in the samples of vegetables and meat foodstuffs commonly found in Manipur, a North Eastern State of India by using atomic absorption spectrophotometer. The concentrations of Zn, Cu, a...
Article
Full-text available
During the last two decades the amount of Zn consumed from Zn-fortified foods and Zn rich dietary supplements have doubled for all age groups and the amount of this will further increase over time. The effect of long term increasing Zn load in the blood lipid profile and tissue minerals status in the body has not been worked out so far. In this stu...
Article
Full-text available
Congenital malformations of neonates are one of the adverse effects of diabetic pregnancy which can be prevented by supplementation of vitamin E and C. The survived neonates usually are at higher risk to diabetes, hypertension, dyslipidemia and cardiovascular diseases that may possibly be prevented through antioxidants administration. In view of th...
Article
Full-text available
Zinc (Zn) is one of the trace minerals which is required for huge range of bodily functions. Since last two decades, Zn as micronutrient is being used indiscriminately in agricultural and hus-bandry practices and also in baby foods and multivitamin supplements since Zn is non-toxic and promotes body weight in the consumers. Thus, the concentration...

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