Kristine Blackham

Kristine Blackham
Universitätsspital Basel · Abteilung für Radiologie & Nuklearmedizin

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87
Publications
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Introduction
Skills and Expertise

Publications

Publications (87)
Article
Background Endovascular treatment in large artery occlusion stroke reduces disability. However, the impact of anesthesia type on clinical outcomes remains uncertain. Methods We compared consecutive patients in the Swiss Stroke Registry with anterior circulation stroke receiving endovascular treatment with or without general anesthesia (GA). The pr...
Article
An artificial intelligence–based tool for intracranial hemorrhage detection on noncontrast CT images was integrated into an emergency department setting to assess diagnostic performance and impact on clinical workflow in an academic center. Authors implemented an artificial intelligence (AI)–based detection tool for intracranial hemorrhage (ICH) o...
Article
Full-text available
Introduction While intracranial aneurysms are common lesions affecting between 1 and 5% of the general population, the prevalence in professional athletes remains unknown. The result is uncertainty and lack of guidelines on appropriate treatment of these patients. Case Presentation A 29-year-old professional soccer player presented in our hospital...
Conference Paper
*Purpose: To assess the effects of a change from free-text reporting to structured reporting on the report review process and turnaround times of resident reports over a 15-months period in the neuroradiology daily routine. *Methods and Materials: Our neuroradiology section introduced in-house developed structured reporting templates for CT examina...
Poster
*Purpose: To classify inaccurately flagged findings (false positives) of a deep learning algorithm for detecting intracranial hemorrhage on CT. *Methods and Materials: We classified false-positive findings of a deep learning algorithm for detecting intracranial hemorrhage on emergent cranial NCCTs obtained at our university hospital between Novembe...
Article
Full-text available
PURPOSE The current literature on the use of brachial artery access is controversial. Some studies found increased puncture site complications. Others found no higher complication rates than in patients with femoral or radial access. The purpose of this study was to determine the impact of ultrasound (US)-guidance on access site complications. MATE...
Conference Paper
Background We report our initial experience with a new stent retriever for mechanical thrombectomy of large- and medium vessel occlusions. Methods We pooled data of four high-volume European stroke centers over the time period from October 2020 to February 2021. Patients were included in our study if the Trevo NXT stent retriever was used as first...
Article
Full-text available
Background Among asymptomatic patients with severe carotid artery stenosis but no recent stroke or transient cerebral ischaemia, either carotid artery stenting (CAS) or carotid endarterectomy (CEA) can restore patency and reduce long-term stroke risks. However, from recent national registry data, each option causes about 1% procedural risk of disab...
Article
Full-text available
Background: The application of a new coating to the delivery wire of the Trevo retriever has the potential to improve its handling. We therefore report our initial experience with this new stent retriever for mechanical thrombectomy of large and medium vessel occlusions. Methods: We pooled data of four high-volume European stroke centers over the t...
Article
Objective In transcarotid artery revascularization (TCAR) the carotid stent used to treat carotid artery stenosis is introduced via a cut-down to the common carotid artery (CCA). Stent placement is performed during flow reversal using an external shunt to the femoral vein. The advantages compared to transfemoral carotid stenting are that the risks...
Article
Full-text available
This Practice Advisory presents a comprehensive and evidence-based set of position statements and recommendations for the use of contrast media in interventional pain procedures. The advisory was established by an international panel of experts under the auspices of 11 multinational and multispecialty organizations based on a comprehensive review o...
Conference Paper
Background The efficacy of endovascular therapy (EVT) as the standard of care for acute ischemic stroke attributable to vessel occlusion improves when delivered quickly. Time metrics have been proposed in order to facilitate quality assurance and there are numerous strategies to streamline workflow. The concept of a combined CT-Angiography-surgical...
Article
Purpose The aim of this study was to demonstrate the value of DCE MRI with high spatiotemporal resolution (GRASP) for differentiating paragangliomas and schwannomas in the head and neck. Methods In a retrospective PACS search of in total 410 patients who had undergone head & neck GRASP-MRI, we identified 6 patients with biopsy proven cervical para...
Article
Background and purpose: Large intracranial vessel occlusion due to calcified emboli is a rare cause of major stroke. We assessed the prevalence, imaging appearance, the effectiveness of mechanical thrombectomy, and clinical outcome of patients with large-vessel occlusion due to calcified emboli. Materials and methods: We performed a retrospectiv...
Article
Reversible vasoconstriction syndrome is a complex of clinical symptoms and angiographic findings, which, while having a mostly benign clinical course, has clinical and imaging overlap with more serious disorders such as vasculitis and aneurysmal SAH and itself includes a minority of patients with fulminant vasoconstriction resulting in severe intra...
Article
Full-text available
We present a case of a 54-year-old man with primary angiitis of the central nervous system (PACNS) who was initially admitted to a psychiatric clinic with a diagnosis of delirium. We discuss the difficulty in establishing the diagnosis of PACNS and provide the reader with some recommendations on how to promptly and correctly diagnose this disease i...
Article
Full-text available
Background and purpose Aneurysms of the posterior inferior cerebellar artery (PICA) are relatively uncommon and evidence is sparse about patients presenting with ruptured PICA aneurysms. We performed an analysis of the Swiss SOS national registry to describe clinical presentation, treatment pattern, and neurological outcome of patients with rupture...
Article
Full-text available
Background: Choroid plexus papillomas (CPPs) are infrequently encountered brain tumors with the majority originating in the ventricular system. Rarely, CPP occurs outside of the ventricles. Case description: We report the case of a recurrent CPP that initially originated within the fourth ventricle, though years later it recurred in the left mid...
Article
Full-text available
Background The treatment of ruptured posterior circulation aneurysms remains challenging despite progresses in the endovascular and neurosurgical techniques. Objective To provide epidemiological characterization of subjects presenting with ruptured posterior circulation aneurysms in Switzerland and thereby assessing the treatment patterns and neur...
Article
Background and purpose: CT Perfusion technique (CTP) is a quantitative, easily performed, accepted and reliable method for detection of ischemic brain changes. Based on calculated parameters, the size of ischemic penumbra and irreversibly damaged infarct core can be determined which helps guide treatment decisions. However, due to the dynamic natu...
Article
Background and purpose: The Sim&Size software simulates case-specific intraluminal Pipeline Embolization Device behavior, wall apposition, and device length in real-time on the basis of rotational angiography DICOM data. The purpose of this multicenter study was to evaluate whether preimplantation device simulation with the Sim&Size software resul...
Article
Full-text available
Grading scales yield objective measure of the severity of aneurysmal subarachnoid hemorrhage and serve as to guide treatment decisions and for prognostication. The purpose of this cohort study was to determine what factors govern a patient's disease-specific admission scores in a representative Central European cohort. The Swiss Study of Subarachno...
Article
BACKGROUND: One-third of patients with aneurysmal subarachnoid hemorrhage (aSAH) have multiple intracranial aneurysms (MIA). OBJECTIVE: To determine the predictors of outcome in aSAH patients with MIA compared to aSAH patients with a single intracranial aneurysm (SIA). METHODS: The Swiss Study of Subarachnoid Hemorrhage dataset 2009-2014 was used t...
Conference Paper
Background Proper sizing of intraarterial devices for aneurysm treatment is crucial to provide safety and ease of deployment while limiting torque, coverage of perforator branches and thrombogenicity. The behavior of an intraarterial device (wall apposition and foreshortening, for example) depends on several factors, including its original length,...
Article
Background: Literature on multiple intracranial aneurysms (MIA) in patients with aneurysmal subarachnoid hemorrhage (aSAH) largely focuses on risk factor analysis and consists essentially of retrospective cohort studies of limited sample size, or else studies in populations outside Europe and North America. Objective: The purpose of this cohort...
Article
Objectives/hypothesis: To illustrate complex interdisciplinary decision making and the utility of modern endovascular techniques in the management of patients with carotid blowout syndrome (CBS). Study designs: Retrospective chart review. Methods: Patients treated with endovascular strategies and/or surgical modalities were included. Control o...
Article
Optical coherence tomography (OCT) is a modern intravascular imaging modality that has the capability to provide detailed, in vivo characterization of the arterial wall and atherosclerotic plaque. The current understanding of the appearance of atherosclerotic plaque via OCT is largely based on coronary arterial studies where OCT information has bee...
Article
This study describes the state of preclinical radiology curricula in North American allopathic, osteopathic, and podiatric medical schools. An online survey of teaching methods, radiology topics, and future plans was developed. The Associations of American Medical Colleges, Colleges of Osteopathic Medicine, and Colleges of Podiatric Medicine listin...
Article
Literature on the anesthetic management of endovascular treatment of acute ischemic stroke (AIS) is limited. Anesthetic management during these procedures is still mostly dependent on individual or institutional preferences. Thus, the Society of Neuroscience in Anesthesiology and Critical Care (SNACC) created a task force to provide expert consensu...
Chapter
The Encyclopedia of the Neurological Sciences explores all areas of the discipline in its 1000+ focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and related areas of neuroscience. The concise entries are all written at a level of comprehension not previously seen in existing literature by contributing authors repre...
Article
Background No randomized controlled trial has successfully compared outcomes between endovascular coiling and microsurgical clipping for unruptured intracranial aneurysms (UIAs). Objective To perform a cost comparison between index hospitalizations of patients with UIAs treated with coil embolization or surgical clipping to identify the current pri...
Article
Literature on the anesthetic management of endovascular treatment of acute ischemic stroke (AIS) is limited. Anesthetic management during these procedures is still mostly dependent on individual or institutional preferences. Thus, the Society of Neuroscience in Anesthesiology and Critical Care (SNACC) created a task force to provide expert consensu...
Conference Paper
Background: Perfusion imaging to guide selection of patients for endovascular treatment of acute ischemic stroke (AIS) remains controversial. CT and MR perfusion have been performed at our institution during evaluation of AIS in order to triage patients who are more likely to benefit from endovascular therapy. The purpose of this study was to compa...
Article
Background: Balloon-mounted coronary stents have been employed in the endovascular management of ischemic cerebrovascular disease, where rapid and precise stenting with angioplasty may be performed in a patient with minimal or no sedation. The Medtronic Driver® balloon-mounted stent is known to have excellent trackability and deliverability, making...
Article
Purpose To determine patient characteristics and size distribution among ruptured and unruptured anterior communicating artery (AComA) aneurysms less than 7 mm treated with coiling or clipping in a 10-year time period at a tertiary referral medical center. A secondary objective is comparison of institutional data to published ISUIA data of 0% 5-yea...
Article
Background: Perfusion imaging to guide selection of patients for endovascular treatment of acute ischemic stroke (AIS) remains controversial. CT and MR perfusion have been performed at our institution during evaluation of AIS in order to triage patients who are more likely to benefit from endovascular therapy. The purpose of this study was to compa...
Conference Paper
LEARNING OBJECTIVES At the end of the session, the audience should have 1) an understanding of the variety of endovascular interventions, 2) comprehension of how diagnostic neuro-imaging affects intervention, and 3) knowledge of the common variations that can affect diagnostic or treatment outcome. ABSTRACT This session will review the clinical an...
Article
Purpose Following installation of a fluoroscopic digital flat panel detector (FPD) in the neuroangiography suite, three patients who underwent repeated angiographic studies for subarachnoid hemorrhage had complications with epilation, with one patient receiving an estimated radiation dose of 12 Gray over the course of 2 months following multiple an...
Article
Background Endovascular intervention is an important treatment option for patients with acute ischemic stroke who are ineligible for intravenous thrombolysis or fail to respond to such therapy. Endovascular treatments include intra-arterial thrombolysis (IAT) and mechanical thrombectomy (MT). Limited data exists regarding the safety and efficacy of...
Article
Background Large French (Fr) sheaths are commonly used to obtain optimum common femoral artery (CFA) access while performing acute stroke endovascular treatments. The StarClose Vascular Closure System (Abott Vascular) is currently indicated for the percutaneous closure of CFA access sheaths of 5 Fr or 6Fr procedural size. Limited data exists regard...
Article
Background There is currently an intense interest in defining predictive profiles from MRI based diffusion/perfusion information for acute ischemic stroke patients. Perfusion/diffusion ratio (mismatch ratio) and penumbra volumes are factors used to select patients for thrombolysis. The current literature considers a mismatch ratio of 1.2 as the min...
Article
Full-text available
Objective To summarize and classify the evidence for the use of endovascular techniques in the treatment of patients with acute ischemic stroke. Methods Recommendations previously published by the American Heart Association (AHA) (Guidelines for the early management of adults with ischemic stroke (Circulation 2007) and Scientific statement indicati...
Article
Full-text available
This is the first in a set of documents intended to standardize techniques, procedures, and practices in the field of endovascular surgical neuroradiology. Standards are meant to define core practices for peer review, comparison, and improvement. Standards and guidelines also form the basic dialogue, reporting, and recommendations for ongoing pract...
Article
Background: As is seen in the early door-to-needle times of intravenous thrombolysis in the treatment of acute ischemic stroke (AIS), prior endovascular management trials have demonstrated early revascularization can lead to improved outcomes. We aimed to study the relationship of the time from acute stroke onset to the time of arterial groin punct...
Article
Background: In the setting of acute ischemic stroke, endovascular intervention, once considered experimental, is now gold standard of care of appropriately selected patients. Among the elderly, aged 80 and above, patients have multiple comorbidities, and little data exists regarding clinical outcome for those undergoing different endovascular treat...
Article
Background: Angiography negative perimesencephalic subarachnoid hemorrhage (SAH) is considered a relatively benign entity compared to aneurysmal SAH. However, some patients with angiography negative perimesencephalic subarachnoid hemorrhage with extension of hemorrhage beyond the perimesencephalic area are at increased risk for vasospasm. Here we p...
Article
BACKGROUND AND PURPOSE: Thromboembolic events are the most common complication seen in elective coil embolization of cerebral aneurysms. Previous studies have shown that administration of oral clopidogrel and/or aspirin may lower the thromboembolic complication rate but little data exists regarding clinical outcome with the use of antiplatelet mono...
Conference Paper
PURPOSE Digital subtraction angiography (DSA) is the established method for follow up evaluation of aneurysms after coiling. However, DSA is an invasive method with and therefore MR imaging has been suggested as an alternative. The aim of this study was to evaluate the diagnostic accuracy of contrast enhanced MRA (CE-MRA) and three dimensional time...
Article
MR imaging of moving patients can be challenging and motion correction techniques have been proposed though some have associated new artifacts. The objective of this study was to semiquantitatively compare brain MR images of moving patients obtained at 1.5T by using partially radial and rectilinear acquisition techniques. FLAIR, T2-, T1-, and contr...
Article
BackgroundCT Perfusion or MR perfusion studies are often used to evaluate patients who presents with Acute Ischemic Stroke (AIS). Little published data are available regarding the real-time use of perfusion imaging to guide endovascular management.Objective To evaluate the role of perfusion imaging in selection and decisions for endovascular manage...
Article
Background Coil embolization of para-ophthalmic artery aneurysms can result in acute as well as delayed visual complications. Progressive visual changes have been have been ascribed to mass effect from aneurysm thrombosis or peri-aneurysmal inflammation or edema. Abrupt, fixed visual changes are likely secondary to thromboembolic complications whic...
Article
Background Reversible vasoconstriction syndrome has been described as an important cause of cerebral arteriopathy and/or vasoconstriction, with non-aneurysmal SAH recently being noted as a more common presentation that previously recognized. No standardized treatment exists and serious complications such as ischemic stroke have been reported. Altho...
Article
BackgroundCT perfusion is used routinely in the acute management of stroke. Core infarct size on perfusion studies affects endovascular management decisions. The literature on correlation of core infarct with follow-up imaging is limited.Objectives To assess the correlation of core infarct on CT perfusion with follow-up imaging.Methods Retrospectiv...
Article
Objective To assess the safety and efficacy of different endovascular treatment modalities in young adults with acute ischemic stroke (AIS).Background Stroke in young adults is less common compared to the elderly but forms a significant burden in terms of morbidity and mortality. Endovascular therapies for AIS are relatively new modalities showing...
Article
Multichannel phased-array head coils are undergoing exponential escalation of coil element numbers. While previous technical studies have found gains in SNR and spatial resolution with the addition of element coils, it remains to be determined how these gains affect clinical reading. The purpose of this clinical study was to determine if the SNR an...