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Publications (121)
To assess whether in animals or patients with ≥ 1 tooth extracted, hyaluronic acid (HyA) application results in superior healing and/or improved complication management compared to any other treatment or no treatment.
Three databases were searched until April 2022. The most relevant eligibility criteria were (1) local application of HyA as adjunct...
Radiographic imaging is key in all phases of dental implant therapy, i.e., diagnosis, planning and assessment of treatment, and long-term monitoring, both in terms of clinical practice and in implant research. Traditionally two-dimensional (2-D) imaging has been the standard in clinical practice and research. However, recent technological advances...
Objectives
The aims of Working Group 1 were to address the role (i) of the buccolingual bone dimensions after implant placement in healed alveolar ridge sites on the occurrence of biologic and aesthetic complications, and (ii) of soft tissue augmentation (STA) on the stability of clinical, radiographic, and patient‐related outcomes of implant treat...
Aim:
To assess whether oral health problems affect disease-specific quality of life (QoL) of inflammatory bowel disease (IBD) patients, and vice versa, whether IBD affects oral-health-related QoL.
Materials and methods:
Individuals reporting IBD and matched controls were surveyed on general anamnestic information, oral-health-related questions a...
Objective:
To map oral health-related standard of care in the context of head and neck cancer (HNC) treatment across the European Union (EU).
Materials and methods:
Six hundred and ninety centers across the European Union were contacted. The questionnaire contained questions focusing on the team/department structure, HNC treatment planning routi...
Background:
To describe the frequency and impact of oral lesions and professional dental care costs in patients with inflammatory bowel disease (IBD) [i.e., Crohn's disease (CD) or ulcerative colitis (UC)] compared to matched controls.
Methods:
IBD patients and matched controls were surveyed on general anamnestic information, eating and drinking...
Objectives:
To assess the impact of implantoplasty (IP) on maximum implant failure strength of narrow diameter implants of different type/design and material, with simulated advanced bone loss.
Materials and methods:
Narrow, parallel-walled implants (3.3 mm in diameter × 10 mm long) with an internal connection of different type/design [bone leve...
Objectives
To summarize the available evidence on the efficacy of power-driven interdental cleaning tools (PDICTs) as an adjunct to tooth brushing compared to tooth brushing alone or tooth brushing combined with any other non-PDICT in terms of interproximal plaque and gingival bleeding reduction in gingivitis patients.
Material and Methods
A syste...
Objective:
To compare the surface roughness of sandblasted, large grit, acid-etched (SLA) surfaced titanium discs, after implantoplasty (IP) with different combinations of rotating instruments without or with the subsequent use of a silicone polisher.
Methods:
Titanium discs (n = 12 per group) with an SLA surface were treated with the following...
Background and objective
Agenesis of the maxillary lateral incisor occurs in up to 4% of all individuals and requires multidisciplinary treatment. Its developmental origins, however, are not fully understood. Earlier studies documented genetic factors contributing to agenesis but also an association with craniofacial morphology. In this study, we a...
Aim:
The aim of this questionnaire-based, case-control study was to assess whether self-reported oral health and periodontitis in ulcerative colitis (UC) and Crohn's disease (CD) patients differ from that in matched controls without inflammatory bowel disease (IBD).
Methods:
A survey including questions on general anamnestic information, IBD dia...
Introduction:
Inflammatory bowel diseases (IBD), encompassing Crohn's disease and ulcerative colitis, are chronic, inflammatory diseases of the gastrointestinal tract. We have initiated a Danish population-based inception cohort study aiming to investigate the underlying mechanisms for the heterogeneous course of IBD, including need for, and respo...
Background
Inflammatory bowel disease (IBD) and periodontitis are chronic, progressive, inflammatory diseases with similarly complex pathogeneses that involve an interplay between dysbiotic microbiota and dysregulated immune-inflammatory responses. However, whether the presence of periodontitis is associated with IBD activity and/or its severity re...
Background:
A subcutaneous emphysema is an infrequent but potentially life-threatening complication after dental treatment involving instruments functioning with pressurized air. Emphysemata after the use of high-speed handpieces and air-syringes are well documented, however, more recently several reports on emphysemata produced by air-polishing d...
Objective
To assess in a cross-sectional study the impact of including dental professionals in the multidisciplinary treatment team of head and neck squamous cell carcinoma (HNSCC) patients on the long-term oral health status.
Materials and methods
Oral health status, dental care behaviours, and oral health–related quality of life were assessed ba...
Objective
To assess whether bacterial colonisation in a power-driven water flosser can be prevented.
Materials and methods
Twenty-four patients undergoing supportive periodontal treatment used 2 power-driven water flossers [Sonicare AirFloss (SAF), AirFloss Ultra (SAFU)] for 12 weeks each as follows: (a) with bottled water (BW); (b) with BW and cl...
Background
Inflammatory bowel disease (IBD) and periodontitis are chronic, progressive, inflammatory diseases with similarities in their respective pathogenesis, which involve a complex interplay between a dysbiotic microbiota and a dysregulated immune-inflammatory response. Periodontitis has been associated with an adverse impact on other inflamma...
In this chapter, the results from a relatively recently performed systematic appraisal of the literature on the long-term outcome of regenerative periodontal treatment in intrabony defects are presented. Periodontal regenerative procedures in intrabony defects yield significantly better clinical outcomes compared with conventional surgery and resul...
Aim
To assess the importance of achieving a successfully treated stable periodontitis patient status (PPS) during long-term supportive periodontal care (SPC).
Methods
This retrospective cohort study included 100 periodontitis patients, who continued for ≥ 7.5 years after active periodontal treatment with SPC and were judged as overall adherent. Th...
Objectives:
To answer the focused question, 'In animals or patients with dental implants, does implant surface characteristics and/or implant material have an effect on incidence and progression of peri-implantitis?'
Material and methods:
Pre-clinical in vivo experiments on experimental peri-implantitis and clinical trials with any aim and desig...
Objective
: The aim of this meta-epidemiological study was to provide an update of the certainty of the evidence in oral health by using the GRADE rating reported in oral health Cochrane systematic reviews (CSR).
Study design and setting
: All interventional oral health CSR published between 2003-2021 were sourced. Study characteristics were extra...
OBJECTIVES The task of working Group 2 at the 6th Consensus Meeting of the European Association for Osseointegration was to comprehensively assess the effects of soft tissue augmentation procedures at dental implant sites on clinical, radiographic and patient-reported outcome measures (PROMs) including an overview on available outcome measures and...
Objectives
The dental alveolus is lined by a thin cortical layer (“bundle bone”, “alveolar bone proper”, “cribriform plate”, “lamina dura”), that can impede access to the bone marrow and its vasculature. During unassisted socket healing, the alveolar bundle bone is gradually resorbed allowing tissue resources from the bone marrow to enter into the...
Background:
This cross-sectional study assessed the potential of colored periodontal probes (CPP) to classify gingival phenotype in terms of gingival thickness (GT).
Methods:
Buccal GT in 3 anterior teeth in each of 50 patients was measured by transgingival sounding and classified by 3 different methods by 8 examiners. Specifically, the diagnost...
Objectives
To assess the reliability of judging the spatial relation between the inferior alveolar nerve (IAN) and mandibular third molar (MTM) based on MRI or CT/CBCT images.
Methods
Altogether, CT/CBCT and MRI images of 87 MTMs were examined twice by 3 examiners with different degrees of experience. The course of the IAN in relation to the MTM,...
Objectives
The task of working Group 2 at the 6th Consensus Meeting of the European Association of Osseointegration was to comprehensively assess the effects of soft tissue augmentation procedures at dental implant sites on clinical, radiographic, and patient-reported outcome measures (PROMs) including an overview on available outcome measures and...
Objectives
To assess patients' opinion on the use of 2 generations of power-driven water flossers and their impact on gingival inflammation.
Material & Methods
In the present prospective cohort study 24 periodontitis patients under regular supportive periodontal therapy used daily 2 generations of a power-driven water flosser (Sonicare AirFloss [S...
Objectives
The present proof-of-principle study assessed whether daily use of a power-driven water flosser (Sonicare AirFloss; SAF) leads to bacterial colonization in the nozzle and/or the device, resulting in contaminated water-jet.
Material and Methods
In five participants, saliva samples at baseline and water-jet samples of devices used daily w...
Non-augmentative surgical therapy of peri-implantitis is indicated for cases with primarily horizontal bone loss or wide defects with limited potential for bone regeneration and/or re-osseointegration. This treatment approach includes a variety of different techniques (e.g., open flap debridement, resection of peri-implant mucosa, apically position...
Objective:
To assess whether the impact of implantoplasty (IP) on the maximum implant failure strength depends on implant type/design, diameter, or material.
Methods:
Fourteen implants each of different type/design [bone (BL) and tissue level (TL)], diameter [narrow (3.3 mm) and regular (4.1 mm)], and material [titanium grade IV (Ti) and titaniu...
Objectives:
To systematically assess the long-term outcome (≥5 years) of root coverage procedures reported in controlled clinical trials.
Material and methods:
Literature search was performed according to the PRISMA guidelines with the following eligibility criteria: (a) English or German language; (b) controlled (CT) or randomised controlled cl...
Aim
To evaluate implant survival and marginal bone levels (MBLevel) at least 5 years after implant installation in patients ≥ 65 years old.
Methods
Patient records were screened retrospectively for the following inclusion criteria: (1) ≥ 65 years of age at the time of implant installation, and (2) ≥ 5‐year radiographic follow‐up or registered impl...
Background
Systematic reviews have established the short‐term improvements of periodontal regenerative/reconstructive procedures compared to conventional surgical treatment in intrabony defects. However, a hierarchy of periodontal regenerative/reconstructive procedures regarding the medium‐ to long‐term results of treatment does not exist.
Aim
To...
Background: Knowledge on peri-implantitis bone defect characteristics and predictors
is still limited.
Purpose: To describe peri-implantitis bone defect characteristics and identify possible
predictors.
Methods: Various parameters at patient- (age, gender, smoking, and supra-structure),
implant- (surface, type, connection, platform, and misfit), an...
Background:
To evaluate whether buccal bone thickness (BBT), implant diameter, and abutment/crown material influence the accuracy of cone beam computed tomography (CBCT) to determine the buccal bone level at titanium implants.
Methods:
Two implant beds (i.e., narrow and standard diameter) were prepared in each of 36 porcine bone blocks. The impl...
Objective
To assess the prevalence and severity of periodontitis based on different diagnostic methods in a historical Austrian population from the early middle ages.
Background
The description of the oral health status of archaeological material can provide interesting insights into prevalence, severity, and extent of oral diseases. Herein, the p...
The purpose of this article is to present a guided lateral window sinus lift (GLSL) procedure with the aid of a fully digital workflow using surgical templates for window osteotomy preparation and implant placement.
A 22-year old patient with insufficient residual bone height in the posterior maxilla was treated with a maxillary sinus augmentation...
Background:
Gingival clefts (GC) develop frequently during orthodontic space closure and may compromise the treatment outcome. This study assessed whether the time-point of orthodontic space closure initiation, after permanent tooth extraction, affects the incidence of GC.
Methods:
In 25 patients requiring bilateral premolar extraction due to or...
Objectives:
To assess, retrospectively, whether older age has an impact on implant osseointegration when compared with younger age.
Methods:
All patients ≥65 years old at implant installation, in an university setting over a time-period of 11.5 years, with complete anamnestic data and follow-up until prosthetic restoration were included and any...
Objectives:
Implantoplasty, i.e., the mechanical modification of the implant, including thread removal and surface smoothening, has been proposed during surgical peri-implantitis treatment. Currently, there is no information about any potential mechanical and/or biological complications after this approach. The aim of the current review was to sys...
Purpose:
To evaluate if periodontists are coherent in their judgement and treatment decisions of patients with different periodontal conditions, and to compare them with general dental practitioners' (GDPs) findings.
Materials and methods:
Eighty-six periodontists participated in a questionnaire study based on four patient cases: (a) generalised...
Purpose:
To assess the effect of the shooting angle variation on linear and planimetric measurements of the pink and white tissues on intraoral photographs.
Methods:
From intraoral three-dimensional (3D) scans of the anterior region in 10 patients, ninety-nine two-dimensional (2D) "scan pictures" each were generated with different shooting angle...
Objectives
To perform a within-subject comparison of the cortical bone micro-architecture of the maxillary sinus floor (MSF) to that of the buccal aspect of the anterior and posterior maxilla.
Methods
Micro-CT scans of the buccal aspect of the anterior and posterior maxilla and of the MSF in 14 human anatomical specimens were recorded. Within-subj...
Objectives
The bucco‐palatal sinus width (SW) appears as relevant factor for graft consolidation after maxillary sinus (MS) floor augmentation. The present study aimed to assess a) SW at different height levels of posterior teeth, b) possible factors influencing SW, and c) whether a simple/meaningful sinus classification based on SW is possible.
M...
When celebrating 100 yr of dental research in the Nordic dental research community (i.e. Nordisk Odontologisk Förening (NOF)), it is relevant to include dental implant treatment. In essence, the successful progress of implant treatment has added both to the quality of life for patients and also to many aspects of professional development and job sa...
The Board of EAO (European Association for Osseointegration) has discussed an initiative to explore the conditions to establish a Dental Implant Register. It was suggested to bring this issue to the EAO Consensus Conference 2018 for a discussion and to possibly propose relevant and manageable parameters. This article presents some select examples f...
Objectives
A considerable portion of the adult population has received and/or is receiving treatment with antiresorptive drugs ( ARD s). It is thus relevant to assess possible side effects of ARD intake in connection to various aspects of implant therapy. The aim of this study was to answer the focused question “In patients with systemic intake of...
Background:
Elevation of the schneiderian membrane, during maxillary sinus floor augmentation (MSFA) may theoretically result in devitalization of adjacent teeth, which are in a close spatial relationship to the sinus floor.
Purpose:
To assess retrospectively the probability of devitalization of teeth adjacent to the osteotomy site after MSFA in...
Objectives:
Impacted and transmigrated mandibular canines differ greatly in incidence, etiopathology, associated anomalies, and treatment prospects, when compared to their maxillary counterparts. The aim of this study was to provide a detailed analysis of 3D radiographic imaging data of impacted mandibular canines.
Materials and methods:
In a re...
Zusammenfassung
Zielsetzung Ein Überblick zu der Thematik „Kieferorthopädie bei Parodontitispatienten“ anhand folgender 3 Fragestellungen: (1) Wann kann man mit der kieferorthopädischen Therapie starten? (2) Worauf muss man während der kieferorthopädischen Therapie achten? (3) Kann das Ergebnis nach abgeschlossener Kieferorthopädie aufrechterhalten...
Die oberen Atemwege als Lebensraum für viele Mikroorganismen haben einen großen Einfluss auf die Tracheotomie, nachdem die Mundhöhle einen Lebensraum für über 700 verschiedene Bakterienspezies darstellt. Bereits im Mundraum (z. B. auf den Zähnen) beginnt kurz nach dem Zähneputzen die Biofilmformation. Das im gesunden Zustand bestehende Gleichgewich...
The cholesterol-lowering drugs, statins, possess anti-inflammatory, antimicrobial and pro-osteogenic properties, and thus have been tested as an adjunct to periodontal treatment. The present systematic review aimed to answer the following focused research question: What is the effect of local and/or systemic statin use on periodontal tissues in pre...
Objectives:
To assess the timeframe between tooth extraction and radiographically detectable socket cortication in humans.
Methods:
Two hundred and fifty patients with a CT scan ≤36 months after tooth extraction were included. First, three orthoradial multiplanar reconstruction slices, representing the major part of the extraction socket, were s...
Introduction:
Sinus floor augmentation is a routinely used surgical technique for increasing the bone height/volume of the atrophic posterior maxilla. Optimal integration of the implanted augmentation material within the newly formed bone will-at least partly-depend on adequate vascularization to ensure sufficient recruitment of osteoblast and ost...
Objectives:
To evaluate the effect of local and/or systemic statin use as an adjunct to non-surgical and/or surgical periodontal therapy.
Data:
Literature search according to PRISMA guidelines with the following eligibility criteria: (a) English or German language; (b) interventional studies; (c) statins as monotherapy or as an adjunct to non-su...
Objectives:
To compare the alveolar bone dimensions in patients with lower second premolar (P2) agenesis prior to and after primary molar loss on CT scans, and assess the possibility for straightforward implant placement.
Methods:
Alveolar bone dimensions were evaluated on 150 mandibular CT scans in three groups: (i) agenesis of P2, with the pri...
Objectives
Vitamin D plays an essential role in bone metabolism as well as in immunity. Hence, it might affect the development and extent of periodontal disease. The aim of this study was the assessment of 25-hydroxyvitamin D (25(OH)D) status in periodontal disease. Materials and methodsTwenty-nine patients with severe periodontal disease and 29 he...
Zielsetzung Ein Überblick zu der Thematik ,,Kieferorthopädie bei Parodontitispatienten“ anhand folgender 3 Fragestellungen: (1) Wann kann man mit der kieferorthopädischen Therapie starten? (2) Worauf muss man während der kieferorthopädischen Therapie achten? (3) Kann das Ergebnis nach abgeschlossener Kieferorthopädie aufrechterhalten werden?
Ergebn...
Objectives
The present systematic review compared the effectiveness of soft tissue substitutes (STSs) and autogenous free gingival grafts (FGGs) in non-root-coverage procedures to increase keratinized tissue (KT) width around teeth. Materials and methodsIncluded studies fulfilled the following main eligibility criteria: (a) preclinical in vivo or h...
The aim of this study was to compare mandibular form (i.e., size and shape) between patients with agenesis of the lower second premolar (P2) and a control group with no agenesis. Three hypotheses were tested: (H1) agenesis causes a change in mandibular morphology because of inadequate alveolar ridge development in the area of the missing tooth (man...
Osteoimmunology describes the cross-talk of cells of the musculoskeletal and the immune system during the pathogenesis of various diseases; among the most prevalent ones is periodontitis, a chronic infectious inflammatory disease of the tooth-supporting structures, i.e., the periodontium consisting of the gingiva, alveolar bone, periodontal ligamen...
Objectives:
The present randomized controlled trial aimed to assess the effect of hyaluronan (HY) injections to augment deficient interproximal papillae at implant-supported crowns in the anterior maxilla.
Methods:
Twenty-two patients with a deficient papilla in the anterior maxilla next to an implant-supported crown were randomly assigned to re...