Krishnamanikumar Premachandran

• Doctor of Philosophy
• Scientist-B at Sathyabama Institute of Science and Technology

Host diet is one of the key factors that shapes insect associated microbial communities, and the impact of dietary shift on abundance of microbial communities and insect fitness is poorly understood. Cigarette beetle ( Lasioderma serricorne (F.)) are in close association with yeast symbionts for nutritional and defence benefits. The present study h...

Insect-microbial symbiosis contributes positively to the physiology of the insect and diet is considered as one important factor determining microbial symbiosis. In this study, we have characterized the microbiota of cigarette beetle, Lasioderma serricorne (Fabricius) on different diets and phases. The beetles were reared on different diet sources...

Cognition is the mental processes and abilities involved in acquiring, storing, retrieving and using it for decision making. Cognitive decline due to aging, lifestyle factor, chronic health conditions, genetic, and environmental factors are rising global concern and propose a potential threat to the cognitive health. The nutritional imbalance has l...

Rice ( Oryza sativa L.) is a crucial staple food crop globally, facing significant challenges from various pests that affect crop productivity and quality. Conventional pesticide usage has limitations, necessitating the development of sustainable pest management strategies. This study focuses on the expression, purification, and functional characte...

Phytocystatins are a type of proteinase inhibitor which are extensively studied for their specific inhibitory action against cysteine protease enzymes (CP) of insects and pathogens. Oryzacystatins (OC), a phytocystatin from rice inhibits CP in a reversible manner with its conserved tripartite wedge. OCs have important role in plant innate defense m...

Cardenolides, a group of cardiac glycosides are potent inhibitors of Na+/K+ ATPase pump in mammals, animals including insects. Some insects can circumvent the toxicity of cardenolides by mechanisms like target site resistance and metabolic resistance resulting in enhanced tolerance or adaptation. In this paper, we report an intriguing observation o...

Brown planthopper resistance NBS-LRR specific R genes (Bph9, Bph14, Bph18, Bph26) have been reported in rice. However, the physical interaction between the expressed BPH R proteins with planthopper salivary proteins remains unclear. In this study, we summarize the interaction of major BPH R proteins with various salivary proteins of rice planthoppe...

Brown planthopper resistant NBS-LRR specific R genes (Bph9, Bph14, Bph18, Bph26) have been reported in rice. BPH specific R genes were clustered with other R genes of rice on chromosome 12 (Bph9, Bph18, Bph26) and 3 (Bph14). Motif analysis of BPH specific R genes showed the predominant motifs as CC, NBS and LRR regions. Bph9, Bph18 and Bph26 R gene...

Phytoprotease inhibitors (PI) are important defence compounds produced by plants against microbes and insect herbivory. Oryzacystatins (OCs) are a group of protease inhibitors from Oryza sativa L. that are specific against cysteine protease enzymes. This study revealed the evolutionary relationship of eleven different oryzacystatins from rice and t...