
Kota Katanoda- Ph.D.
- Chief at National Cancer Center, Japan
Kota Katanoda
- Ph.D.
- Chief at National Cancer Center, Japan
Editor-in-Chief of the Journal of Epidemiology, the official journal of the Japan Epidemiological Association
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Introduction
Current institution
Publications
Publications (265)
Background
Japan’s ‘Health Japan 21’ initiative targets a reduction in adult smoking prevalence to 12% by 2032. This study evaluates the probability of meeting this target at both national and prefectural levels by estimating and comparing prevalence trends.
Method
Using crude smoking prevalence data from 2001 to 2022 for the whole nation and acro...
While male breast cancer (MBC) remains a rare and understudied disease, comparatively little is known about its prognosis in contrast to female breast cancer (FBC). There is a paucity of large population‐based studies comparing the prognosis of MBC patients to FBC patients in Japan. This study analyzed 181,540 breast cancer cases, 1058 (0.6%) males...
Importance
Although evaluation of geographic area inequities in vaccination is crucial to identify areas that need community-based interventions, knowledge of disparities in human papillomavirus (HPV) vaccination uptake remains limited in Japan.
Objective
To investigate the association of female cumulative HPV vaccination uptake with neighborhood-...
Adult primary brain and central nervous system (CNS) cancers, though comprising only about 4% of new cancer diagnoses, significantly impact morbidity and mortality due to their low survival rates. Globally, brain and CNS tumor incidence varies considerably, with the United States exhibiting one of the highest rates and Japan among the lowest worldw...
Despite the importance of genetic testing for risk assessment and treatment in breast cancer, the prognostic impact of germline pathogenic variants (PVs), especially in Asian populations, is unclear. We assessed the impact of germline PVs in patients with early‐stage breast cancer. This study included 7278 Japanese multihospital registry patients....
Objectives To examine a comprehensive monitoring framework for health inequalities in Japan, this study aimed to quantify educational inequalities in mortality and its regional variations, which are widely used internationally as outcome measures of health inequalities.Methods Individual data were obtained from the 2010 Population Census and Vital...
Background: Amidst the global coronavirus disease (COVID-19) pandemic, Japan has faced a significant public health challenge, evident from the significant increase in mortality rates since 2021. This study described the variations in all-cause and cause-specific changes in mortality up to 2022 in Japan.
Methods: This study used official Vital Stati...
Objectives This study aimed to evaluate Japanese smokers' perceptions of health warnings on tobacco packaging by comparing text-only and pictorial warnings.Methods Data were sourced from the Japan Society and New Tobacco Internet Survey (JASTIS), an online, self-reported study conducted in February and March 2020. Participants included current smok...
Background
In April 2020, Japan’s revised Health Promotion Act (HPA) banned cigarette smoking and heated tobacco products (HTP) use in indoor public places but exempted small establishments and permitted smoking-designated/HTP-designated rooms. This pre–post study evaluated the effectiveness of the HPA.
Methods
Data were from waves 1 to 4 (2018–20...
Background
During the coronavirus disease (COVID-19) pandemic, essential workers (e.g. medical workers) may be at a high prevalence of contracting COVID-19; however, the trend remains unclear in Japan. This study aimed to investigate occupational differences in the prevalence of COVID-19.
Methods
Data were retrieved from the 2022 Japan COVID-19 an...
Introduction
The global shift toward working from home due to the COVID-19 pandemic has led to concerns about increased sedentary behavior and its potential impact on work engagement, a critical factor for employee well-being and organizational productivity. This study aims to explore the association between sedentary time and work engagement among...
Recent advances in treating colorectal cancer (CRC) have increased the importance of multidisciplinary treatment. This study aimed to clarify trends in the treatment and survival of CRC using population‐based cancer registry data in Japan. We analyzed the survival of CRC cases diagnosed from 1995 through 2015 from a population‐based cancer registry...
Introduction
The global market of flavour capsule cigarettes (FCCs) has grown significantly over the past decade; however, prevalence data exist for only a few countries. This study examined prevalence and perceptions of FCCs among adults who smoke across five countries.
Methods
Cross-sectional data among adults who smoked cigarettes came from the...
Background
The Japanese 2020 cervical screening guidelines recommend conventional cervical cytology screening every 2-years for women aged 20–69 years. The nonavalent human papillomavirus (HPV) vaccine has also recently been approved in Japan. We therefore evaluated the cost-effectiveness of cervical cancer screening strategies alongside universal...
Background
Due to the lack of a national mortality inequality monitoring framework, the overall picture in Japan remains unclear. Here, we investigated educational inequalities in mortality and their cause-specific contribution in Japan.
Method
Data were obtained by linking the 2010 Japanese population census and death records between 1 October 20...
Introduction
In Japan, heated tobacco products (HTPs) are promoted by the tobacco industry as reduced-risk tobacco products despite the lack of evidence for this claim. This study determined the distribution of HTP-harmfulness perception and identify the explanatory factors associated with the perception of HTP as less harmful than conventional cig...
"Tobacco harm reduction" is defined as a method to minimize harm and risk of death and disease without eliminating tobacco and nicotine use. In Japan, where heated tobacco products (HTPs) are prevalent, the tobacco industry is progressively endorsing the concept of "tobacco harm reduction." Therefore, stakeholders in tobacco control must urgently s...
Advances in diagnostic techniques and treatment modalities have impacted head and neck cancer (HNC) prognosis, but their effects on subsite‐specific prognosis remain unclear. This study aimed to assess subsite‐specific trends in mid‐ and long‐term survival for HNC patients diagnosed from 1993 to 2011 using data from population‐based cancer registri...
Background
We provide comprehensive sex-stratified projections of cancer prevalence for 22 cancer sites in Japan from 2020 to 2050.
Methods
Using a scenario-based approach, we projected cancer prevalence by combining projected incidence cases and survival probabilities. Age-specific incidences were forecasted using age–period–cohort models, while...
Objective
The COVID-19 pandemic led to an increase in mortality in most countries in 2020, deviating from prior decreasing trends. In Japan, however, mortality was suggested to decrease in 2020. This study investigated long-term mortality trends and cause-specific contributions, focusing on the period of the COVID-19 pandemic in Japan.
Design
We a...
Objective:
Although there is increasing evidence to suggest the cost-effectiveness of aspirin use to prevent colorectal cancer (CRC) in the general population, no study has assessed cost-effectiveness in patients with familial adenomatous polyposis (FAP), who are at high risk of developing CRC. We examined the cost-effectiveness of preventive use...
Background: Hyogo Prefecture has managed smoking ban legislation with partial restrictions in public places (Hyogo-L) since 2013. Previous studies have reported a significant decrease in admissions for acute coronary syndrome (ACS) in Kobe-city, but not in other districts of Hyogo Prefecture in the 2 years after Hyogo-L. The aim of the present stud...
Characterizing trends in mortality rates with consideration of trends in incidence rates at the population level could help identify unmet needs in public health and provide essential indicators of cancer control. In the late 20th century, the arrival of the first molecular targeted agent, rituximab, for non-Hodgkin lymphoma (NHL) led to a paradigm...
Cancer in children, adolescents, and young adults (AYAs) although rare, is the leading disease-specific cause of death in Japan. This study aims to investigate cancer incidence and type of treatment hospital among children and AYAs in Japan. Cancer incidence data (2016-2018) for those aged 0-39 years were obtained from the Japanese population-based...
Cancer registry data provide a very important source of information for improving our understanding of the epidemiology of various cancers. In this work, we estimated the 5‐year crude probabilities of death from cancer and from other causes for five common cancers, namely stomach, lung, colon‐rectum, prostate and breast, in Japan, using population‐...
Controlling avoidable causes of cancer may save cancer-related healthcare costs and indirect costs of premature deaths and productivity loss. This study aimed to estimate the economic burden of cancer attributable to major lifestyle and environmental risk factors in Japan in 2015. We evaluated the economic cost of cancer attributable to modifiable...
We explored whether coronavirus disease 2019 (COVID-19)-related distress was associated with voluntary suspension of medically-assisted reproduction (MAR) treatment from April to May 2020 in Japan. Data for 1,096 candidate respondents were collected from a Japanese nationwide cross-sectional internet survey distributed from August 25 to September 3...
Background:
The 2015 Japan Standard Population (2015 JSP) was established in response to changes in the age structure. However, the effects of major updates, especially the recategorization of older age groups, for interpreting various health metrics have not been clarified.
Method:
Population data were collected and estimated for older age cate...
Worldwide, research based on geographic information of official statistical data, including cancer registries, is utilized for cancer control and public health policies. The National Cancer Registry of Japan was launched in 2016, making it possible to use data on cancer incidence systematically. Given the nature of this comprehensive survey, the us...
Objective
To examine the status of food expense insufficiency in Japan during the coronavirus disease 2019 (COVID-19) pandemic and the socioeconomic and sociodemographic factors associated with food expense insufficiency.
Design
Food expense insufficiency before and after the pandemic was assessed. The multivariable-adjusted odds ratio (AOR) and 9...
Purpose:
The aim of this study was to project new cancer cases/deaths forward to 2054, and decompose changes in cancer cases/deaths to assess the impact of demographic transitions on cancer burden.
Methods:
We collected data on cancer cases/deaths up to 2019, empirically validated the projection performance of multiple statistical models, and se...
Objective We aimed to investigate the prevalence of COVID-19 vaccination and approval rating of the social implementation of its certification to stimulate economic activities such as travel and restaurant use ("vaccine passport").Methods Using data from the Japan COVID-19 and Society Internet Survey (JACSIS) conducted in September-October 2021, we...
Objectives:
This study aimed to examine whether and how the COVID-19 pandemic has affected the postponement or cancellation of elective surgeries in Japan.
Design and setting:
A cross-sectional, web-based, self-administered survey was conducted nationwide from August 25 to September 30 2020. We used data from the Japan 'COVID-19 and Society' Int...
Objective
This study aimed to quantify the long-term impact of implementing the WHO Framework Convention on Tobacco Control (FCTC) compliant tobacco control measures, MPOWER, on smoking prevalence and mortality in men and women aged ≥20 years in Japan.
Design
A Stock-and-Flow simulation model was used to project smoking prevalence and mortality fr...
Background
National HPV vaccination coverage in Japan is less than one percent of the eligible population and cervical cancer incidence and mortality are increasing. This systematic review and meta-analysis aimed to provide a comprehensive estimate of HPV genotype prevalence for Japan.
Methods
English and Japanese databases were searched to March...
Background:
Since 2011, commercial truck drivers have been required to take alcohol breath tests at the beginning and end of their working hours due to their employers' legal obligations. However, non-commercial truck drivers are not required to do so. We examined whether alcohol-related crashes had decreased after 2011 among commercial truck driv...
Aims:
Among colorectal cancer (CRC) patients, preexisting diabetes is suggested to influence poor prognosis, but the impact on adjuvant chemotherapy implementation is largely unknown. We aimed to compare the implementation rate of adjuvant chemotherapy between CRC patients with and without preexisting diabetes in a retrospective cohort study.
Met...
In Japan, risk behaviors for cancer remain inadequately controlled, often due to a lack of necessary information and support to guide consumers in cancer control decisions. The use of strategic health communication efforts based on social marketing has substantial potential to provide groups of consumers who are underinformed or misinformed with re...
Background:
Studies on the impact of coronavirus disease 2019 (COVID-19) on people's routine medical care are limited, and understanding the factors associated with medical care avoidance can inform us about the ongoing pandemic.
Objectives:
We aimed to assess the impact of Japan's state of emergency and stay-at-home policy for COVID-19 on hospi...
In most high-resource countries with organized screening programs, the incidence and mortality of cervical cancer is decreasing. Recent statistics have also revealed a reduction in invasive cervical cancer incidence as a result of national vaccination programs. Paradoxically, cervical cancer incidence has increased in Japan, particularly amongst wo...
Objectives
Promoting smoke-free policies is a key intervention for reducing secondhand smoke (SHS) exposure. During the COVID-19 pandemic in Japan, many indoor smoking spaces in workplaces were closed. This study aimed to reveal the association between a workplace smoke-free policy and SHS exposure among non-smoking employees, distinguishing betwee...
Continued decrease in smoking prevalence and increasing use of sensitive diagnostic procedures necessitate updated monitoring of trends in lung cancer incidence in Japan. We analyzed histology‐ and stage‐specific trends in 1993 to 2015 using data from 62 870 diagnosed cases from the Monitoring of Cancer Incidence in Japan project. After applying a...
Background
Patients with comorbidity are at higher risk of deteriorating COVID-19, but they need to access healthcare services regularly for their primary disease. This study aimed to investigate whether patients restricted healthcare utilization due to the COVID-19 pandemic and to understand the relations between restriction of healthcare utilizat...
Background:
While esophageal squamous cell carcinoma (ESCC) is the predominant histological type in Japan, concern has been expressed over an increase in the proportion of esophageal adenocarcinoma (EAC), especially in middle-aged populations. This study aimed to assess long-term trends in esophageal cancer incidence by histological type.
Methods...
The This study estimated the cancer burden attributable to modifiable factors in Japan in 2015 using the best available epidemiological evidence and a standard methodology. We selected the following factors for inclusion in the estimates, namely tobacco smoking (active smoking and secondhand smoking), alcohol drinking, excess bodyweight, physical i...
Salt consumption is high in most parts of the world, particularly among populations in Asia-Pacific region, including Japan. The recent portion of global deaths attributable to excess salt was largest among dietary exposures. We estimated the cancer in 2015 attributable to highly salted food in the Japanese population. Consumption of highly salted...
PM2.5 is a major environmental health problem and a risk factor for lung cancer. Exposure to PM2.5 has attracted growing public concern nationwide. Here, we aimed to estimate the cancer in 2015 attributable to PM2.5 in Japan. Ambient air pollution level due to excess concentration of PM2.5 was estimated using geophysically based satellite-derived P...
The International Agency for Research on Cancer has evaluated red meat as probably carcinogenic and processed meat as carcinogenic to humans. The World Cancer Research Fund and American Institute for Cancer Research concluded there is convincing evidence that consumption of processed meat increases the risk of colorectal cancer. We estimated the nu...
We estimated the population attributable fraction (PAF) of cancers in Japan attributed to never breastfeeding in 2015. The data on breastfeeding in Japan were derived from two sources. Data on women aged younger than 40 were obtained from the Longitudinal Survey of Babies in the 21st Century (LSB21); those for women aged 40 to 69 was derived from t...
Exogenous female hormone use has not been as popular in Japan as in western populations. Here, we estimated the population-attributable fraction (PAF) of cancers in Japan in 2015 attributed to exogenous female hormone use. We used the most recent prevalence data for oral contraceptives (OC) and hormone replacement therapy (HRT), available from a la...
Population attributable fraction (PAF) offers a means to quantify cancer burden that is attributable to a specific etiological factor. To better characterize the current cancer burden due to infection in the Japanese population, we estimated the PAF for cancer incidence and mortality in 2015 that could be attributable to infectious agents, includin...
Overweight and obesity are known contributors to many non-communicable diseases, including cancer, and affect over one-tenth of the global population. One way to maintain a healthy weight and reduce the risk for cancer is through increased physical activity. We estimated the fraction of cancer incidence and mortality in 2015 attributable to excess...
Tobacco is the greatest single cause of many non-communicable diseases, including cancer. We calculated the proportion of cancer incidence and mortality in 2015 attributable to tobacco smoking and exposure to secondhand smoke (SHS). Data on the prevalence of active smoking were derived from the 2005 Japanese National Health and Nutrition Survey by...
Consumption of vegetables, fruit and dietary fiber is closely associated with cancer incidence and mortality in the population, especially under conditions of insufficient consumption. We estimated the fraction of cancer incidence and mortality in 2015 attributable to insufficient consumption of vegetables, fruit and dietary fiber in the Japanese p...
Alcohol can cause or contribute to the development of many non-communicable diseases, including cancer. We calculated the proportion of cancer incidence and mortality in 2015 attributable to alcohol consumption in 2005. Data on alcohol consumption, provided in go, a traditional Japanese alcohol measurement unit, was derived from the 2005 Japanese N...
Background
Screening is one of the effective interventions for the reduction of colorectal cancer mortality. Though the Japanese government recommends faecal occult blood test and colonoscopy as a follow-up examination following a diagnosis, both participation rates have not been so high and the national mortality rate has not shown a clear decreas...
Objective
We examine international incidence trends of lung, colorectal, prostate, and breast cancers, as well as all cancers combined excluding non-melanoma skin cancer (NMSC) in adults aged 50 and older, over a fifteen-year period using data from 113 high quality population-based cancer registries included in the Cancer in Five Continents (CI5) s...
According to national cancer registry data in Japan, approximately 20,000 adolescents and young adults (AYAs, age 15–39 years) are newly diagnosed with cancer each year. Improvements in treatment and care for AYAs with cancer are included in the Phase Three Basic Plan to Promote Cancer Control Programs in Japan. This article reviews current cancer...
Background:
The use of heated tobacco products (HTPs) has increased exponentially in Japan since 2016; however, their effects on health remain a major concern.
Methods:
Tsuruoka Metabolome Cohort Study participants (n = 11,002) were grouped based on their smoking habits as never smokers (NS), past smokers (PS), combustible tobacco smokers (CS),...
Background
Increasing proportions of smokers in Japan smoke <10 cigarettes per day (CPD). Yet, the health risks of low-intensity smoking in Asia are poorly understood.
Methods
We performed a pooled analysis of 410 294 adults from nine population-based prospective cohort studies participating in the Japan Cohort Consortium. Cigarette-use data were...
:
Comprehensive genomic profiling has been approved for use in patients with advanced solid tumours; however, it is only indicated in advanced solid tumour patients without available standard chemotherapeutic treatment or those who have completed standard treatments in Japan, and there are no available data on the clinical feasibility and utility...
Background
Preexisting diabetes may contribute to the indication for adjuvant chemotherapy among patients with colorectal cancer (CRC); however, the association between diabetes and its implementation is largely unknown.
Methods
We analyzed the hospital-based cancer registry and health claims data of patients with stage III CRC who received curati...
Background
During the long-term economic recession, health inequalities have been concerned in Japan. Among cancer mortality rates, the widest socioeconomic inequalities of municipal mortality was observed in lung cancer. Our aim was to examine the trends in the inequality by sex and age group.
Methods
We used the areal deprivation index (ADI) to...
Background
Shoulder stiffness is a common health issue in Japan. During the COVID-19 pandemic, people were forced to stay home which possibly escalated the development of shoulder stiffness. We aimed to assess associations of lifestyle changes and newly developed neck and shoulder pain (NSP) during the pandemic.
Methods
A cross-sectional study was...
While the age-standardized mortality rate in Japan is decreasing for all cancers as a whole, this is not the case for some major site-specific cancers. We descriptively compared trends in all-cancer and site-specific cancer mortality in Japan and selected countries. Data on age-standardized cancer mortality rates in six countries (Japan, the USA, t...
Background
In response to the Coronavirus-19 (COVID-19) pandemic, the Japanese government declared a state of emergency in Saitama, Chiba, Tokyo, Kanagawa, Osaka, Hyogo and Fukuoka prefectures on April 7, 2020; this was extended to the remaining prefectures on April 16, 2020. The state of emergency was lifted on May 25, 2020. Although it was known...
Tobacco smoking is the number one preventable cause of disease and death in China as it is globally. Indeed, the toll of smoking in China is much greater than its status as the world's most populous country. There is a persistent and continuing need for China to implement the measures specified in the global tobacco control treaty, the World Health...
Background
Despite prophylactic human papillomavirus (HPV) vaccination being a safe, effective and cost-effective public health intervention for the prevention of cervical cancer, the HPV vaccine is not actively recommended or promoted by the Ministry of Health Labour and Welfare in Japan. With already very low levels of cervical screening below 30...
Objectives
Japan is currently the biggest market of heated tobacco products (HTPs) in the world. Little is known about nicotine dependence among HTP users. Thus, the objective was to assess the association of type of tobacco use and time-to-first-use, a marker of nicotine dependence.
Methods
A cross-sectional analysis of the 2019 data from an inte...
Background: Unlike many North American and European countries, Japan has observed a continuous increase in cancer incidence over the last few decades. We examined the most recent trends in population-based cancer incidence and mortality in Japan.
Methods: National cancer mortality data between 1958 and 2018 were obtained from published vital statis...
Background:
A national endoscopic screening program for gastric cancer was rolled out in Japan in 2015. We used a microsimulation model to estimate the cost-effectiveness of current screening guidelines and alternative screening strategies in Japan.
Methods:
We developed a microsimulation model that simulated a virtual population corresponding t...
Previously, the main treatment for multiple myeloma (MM) was cytotoxic chemotherapies, including autologous stem‐cell transplantation (ASCT), but survival benefit in the elderly was limited. More recently, clinical trials and practical experience with novel agents with superior efficacy have shown improved survival, including in the elderly. Howeve...
The main objective of this study was to estimate the cumulative mortality risk for lung cancer according to smoking status and exposure to secondhand smoke (SHS) in Japan. We applied a life-table method to estimate the cumulative risk. Estimated lifetime cumulative risk for 20-year-old non-smokers, former, and current smokers was 3.2%, 7.6%, and 14...
Cancer patients with diabetes experience a poorer prognosis, yet the population burden of this multimorbidity remains unknown. This study aims to estimate the latest incidence and prevalence of cancer with diabetes mellitus in Japan. We used projection of cancer incidence and latest survival data from population‐based cancer registries. Incidence o...
Background:
This study aimed to assess long-term trends in the incidence of prostate cancer by stage at diagnosis before and after the introduction of population-based PSA screening.
Methods:
We used data from three population-based cancer registries in Japan. A total of 29,458 malignant prostate cancer cases diagnosed between 1993 and 2014 were...
Objective This report aimed to present policy recommendations on the regulation of heated tobacco products based on a review of the literature on the use of heated tobacco products, component analysis of harmful chemical substances, and product characteristics as nicotine delivery device, and on an examination of the influence of the product's incr...
The incidence of breast cancer among Japanese women is substantially increasing. This study evaluated the effects of reproductive and lifestyle factors with respect to breast cancer overall and separately among pre- and postmenopausal women using data from the Three-Prefecture Cohort Study of Japan.
A total of 33,410 women aged 40 to 79 years compl...
Objectives
In Japan, prostate cancer constitutes the fourth common cancer and the sixth major cause of cancer death in men. Despite the rising incidence, it remains unclear whether Prostate Specific Antigen (PSA) screening has contributed to early detection and subsequent reduction in late-stage incidence of and mortality from prostate cancer, or i...
Objective
Smoking rate varies across Japanese prefectures. However, it isn’t clear whether there are differences in trends in smoking rate by prefecture. In this study, we estimated the trend in smoking rate by prefecture and categorized by feature.
Methods
Male smoking rates by prefecture from 2001 through 2016 were obtained from dataset which is...
Figure S1 ¦ Direct and mediating effects of bodyweight indices at three different life stages on adult‐onset diabetes, among women with parental history of diabetes.
Table S1 ¦ Age‐adjusted odds ratios for being diagnosed with adult‐onset diabetes according to the combined categories of birthweight and body mass index at two different life stages (entire analytic cohort).
Background: Coffee, which contains various bioactive compounds, is one of the most popular beverages. Further accumulation of evidence is needed, however, to confirm whether coffee consumption would be effective in preventing cardiovascular disease in the general Japanese population.
Methods and Results: We evaluated the association between coffee...
Questions
Questions (2)
I want to conduct path analysis with logistic regression model.
Exposure variables are continuous (body weights at different time points), and mediator variables are also continuous (age etc.).
Outcome is dichotomous variable (existence of a disease).
My interests are the direct and indirect effects of exposure variables on the outcome. So I am trying to do path analysis with logistic regression model.
I use SAS, but I could not find how to apply logistic model with PROC CALIS.
Are there any options to select logistic model? or some other procedures?
This may be done by conducting several regression analyses and re-calculating the output coefficients, but I want to avoid self calculation.
Some websites say it can be done by Mplus. Is it an easier way to use Mplus?
I am looking for a standard way to calculate risk-factor-specific incidence rate from overall population incidence rate. The available data are overall population incidence rate of a disease, prevalence of a risk factor, and relative risk of that disease according to the risk factor. What I want to do is to estimate the incidence rate of people with or without that risk factor. My image is to allocate the overall incidence rate into two groups (risk factor holders and non-holders), keeping consistency with the overall incidence rate. Are there any good references?